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iron-regulatory protein 1
iron-regulatory protein 1

... been previously described by Moeder et al. [20] and was named KO-661 [20]. Lines homozygous for the disruption were isolated, and used for further studies. When the mutants were grown in a greenhouse, or in hydroponic cultures under controlled conditions, they displayed no macroscopic phenotype. Fur ...
Regulation and Flexibility of Genomic Imprinting
Regulation and Flexibility of Genomic Imprinting

... erased and reset in the germ line for the next generation. Genomic imprinting seems to irreversibly set the epigenetic state of certain parental alleles during gametogenesis in animals. As a result, it prevents normal development of gyno- and androgenotes, which carry two maternal or paternal genome ...
PDF - Journal of Genomics
PDF - Journal of Genomics

... acids and carbohydrates that are abundant in their phloem-based diet or produced by the host. Genomic evidence suggests that several amino acid biosynthetic pathways are shared between aphid and Buchnera, providing the aphid the ability to regulate the endosymbiont’s metabolism (16). No aphid specie ...
Sequence Note Complete 59 Long  Terminal Repeat, nef,
Sequence Note Complete 59 Long Terminal Repeat, nef,

... suggesting relatedness. Most of the significant domains such as those involved in CD4 and MHC-I downregulation as well as altering of cell signaling are found to be well conserved in all sequences and variations correlate with results obtained in previous studies.17,19–22 Furthermore, considering th ...
Different strategies of osmoadaptation in the closely
Different strategies of osmoadaptation in the closely

... have to deal with the problem that water follows the osmotic gradient. Cells unable to cope with osmotic stress will become dehydrated. This will eventually disrupt cellular metabolism, and so is used in food conservation by pickling. One strategy to thrive in such environments involves the producti ...
Can blue-eyed parents produce brown
Can blue-eyed parents produce brown

... determinant of human eye colour The physical basis of eye colour is determined by the distribution and content of the melanocyte cells in the anterior stroma of the eye (Figure 3). In the brown iris there is an abundance of mature melanosomes within the melanocytes of the stroma, whereas the melanoc ...
Profile of Edward M. De Robertis - Howard Hughes Medical Institute
Profile of Edward M. De Robertis - Howard Hughes Medical Institute

... Club modeled around European seminars in Cambridge and Basel. “It is still running and has provided a wonderful forum for discussions,” De Robertis says. In 1988, a book (6) by embryologist Viktor Hamburger, as well as one by embryologist Hans Spemann (7) who taught Hamburger, sparked discussion in ...
View PDF
View PDF

... paper ...
Case Report Clinical Expression of an Inherited Unbalanced
Case Report Clinical Expression of an Inherited Unbalanced

... major clinical problem since childhood. She did not have a single miscarriage so far, and she was able to achieve a pregnancy immediately after marriage with no medical intervention. However, any balanced translocation requires at least one chromosome break on each participating chromosome which mig ...
15q13.3 microdeletion syndrome - Unique The Rare Chromosome
15q13.3 microdeletion syndrome - Unique The Rare Chromosome

... kidneys detected at the 20-week ultrasound scan and thereafter had regular scans for the remainder of the pregnancy. The baby was induced at 36 weeks due to the mother’s pre-eclampsia (a sudden increase in blood pressure and the presence of excess protein in the urine. If left untreated, pre-eclamps ...
Correcting the Bias of WRIGHT`S Estimates of the Number of Genes
Correcting the Bias of WRIGHT`S Estimates of the Number of Genes

... can be calculated for some organisms. Theoretical analysis and an analysis of the Drosophilaon data distributionsof effects of P element insertson bristle numbers indicate that the value of the composite parameter is likely to be about three or larger for many quantitative characters.There are,howev ...
Multilocus genetic models of handedness closely resemble
Multilocus genetic models of handedness closely resemble

... Although our GWAS analysis found no significant associations, a key question is whether those analyses are compelling evidence against a single gene for handedness, or whether perhaps there was simply insufficient power to convincingly be able to come to a negative conclusion. Formal power calculati ...
INVESTIGATING THE IMPORTANCE OF ANATOMICAL
INVESTIGATING THE IMPORTANCE OF ANATOMICAL

... human diseases, transferring knowledge among model organisms, and studying the genetic basis of evolutionary innovations. Two organismal features, whether genes, anatomical parts, or any other inherited feature, are considered to be homologous when they are evolutionarily derived from a single featu ...
The genetic epidemiology of idiopathic scoliosis
The genetic epidemiology of idiopathic scoliosis

... animal research), previous genetic studies showing an association (replication studies), or positional information gained from linkage studies (in combination with hypotheses). Between 1992 and 2006, many candidate gene studies for IS were family-based linkage studies [14–19]. Whereas family-based m ...
View/print full test page
View/print full test page

... o Deletion/duplication analysis is performed using a high resolution, custom microarray platform designed to target the genes of interest at the exon level. Detection rates are limited to the genes specified; this test does not provide whole genome analysis. Gene panels are a more cost-effective app ...
Codon usage bias from tRNA`s point of view
Codon usage bias from tRNA`s point of view

... species. Surprisingly, despite the wide G+C variation of bacterial genomes these anticodons are the same in most genomes. This suggests an optimization of the translation machinery to use a small subset of optimal codons and anticodons in fast-growing bacteria and in highly expressed genes. As a res ...
Document
Document

... values with big differences between them. However, out of focus arrays will have some of the big values falling into their small neighbours so that the differences will be smaller. ...
Association of KCNQ1, KCNE1, KCNH2 and SCN5A Polymorphisms
Association of KCNQ1, KCNE1, KCNH2 and SCN5A Polymorphisms

... association between this polymorphism and QTc length in a normal German population of twins and showed that subjects with SCN5A IVS24+116 A/A genotype had longer QTc than subjects with SCN5A IVS24+116 G/G15. Additional studies in large series are needed to elucidate whether or not this polymorphism ...
SEX-DETector: a probabilistic approach to uncover sex
SEX-DETector: a probabilistic approach to uncover sex

... Although this RNA-seq cross-based strategy is very promising for studying sex chromosomes in nonmodel organisms, the existing approaches have a number of limitations due to the fact that inference of sex-linkage was done with empirical filters and without a statistical framework. Once RNA-seq reads ...
Genetic Dissection of a Genomic Region with Pleiotropic Effects on
Genetic Dissection of a Genomic Region with Pleiotropic Effects on

... positions, annotate candidate genes, and characterize important genomic features (Schnable et al. 2009). Previous work in maize and its wild progenitor suggests the genes responsible for phenotypic change are scattered throughout the genome, but with several concentrations of genes (QTL) controlling ...
ECBB 2016 Abstract book.
ECBB 2016 Abstract book.

... From uni- to multimodal signaling: towards an integrative view on anuran communication ...
J Mol Evol (2007) 65:541–554 - digital
J Mol Evol (2007) 65:541–554 - digital

... whereas in the chicken the B-complex codes for only two class I and two class II genes. These findings led to the formulation of the minimal essential MHC hypothesis (Kaufman and Salomonsen 1997), which highlights that the chicken MHC is selected to be as small and compact as possible, containing on ...
Abundant Genetic Overlap between Blood Lipids and Immune
Abundant Genetic Overlap between Blood Lipids and Immune

... blood lipid levels and immune-mediated diseases, including Crohn’s disease (CD), ulcerative colitis (UC), rheumatoid arthritis (RA), type 1 diabetes (T1D), celiac disease (CeD), psoriasis (PSOR) and sarcoidosis (SARC)[1–5]. In addition to diet and other environmental factors, it is possible that the ...
Multilocus genetic models of handedness closely resemble
Multilocus genetic models of handedness closely resemble

... Although our GWAS analysis found no significant associations, a key question is whether those analyses are compelling evidence against a single gene for handedness, or whether perhaps there was simply insufficient power to convincingly be able to come to a negative conclusion. Formal power calculati ...


... of the EGF receptor (Egfr) pathway. Moreover, loss-offunction phenotypes of the Egfr pathway are suppressed by ash2 mutants, while gain-of-function phenotypes are enhanced. Our results also show that ash2 acts as a ...
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Biology and consumer behaviour

Consumer behaviour is the study of the motivations surrounding a purchase of a product or service. It has been linked to the field of psychology, sociology and economics in attempts to analyse when, why, where and how people purchase in the way that they do. However, little literature has considered the link between our consumption behaviour and the basics of our being, our biology. Segmentation by biological driven demographics such as sex and age are already popular and pervasive in marketing. As more knowledge and research is known, targeting based on a consumers biology is of growing interest and use to marketers.As human machines being made up of cells controlled by our brain to influence aspects of our behaviour, there must be some influence of biology on our consumer behaviour and how we purchase as well. The nature versus nurture debate is at the core of how much biology influences these buying decisions, because it argues the extent to which biological factors influence what we do, and how much is reflected through environmental factors. Neuromarketing is of interest to marketers in measuring the reaction of stimulus to marketing. Even though we know there is a reaction, the question of why we consume the way we do still lingers, but it is a step in the right direction. Biology helps to understand consumer behaviour as it influences consumption and aids in the measurement of it.Lawson and Wooliscroft (2004) drew the link between human nature and the marketing concept, not explicitly biology, where they considered the contrasting views of Hobbes and Rousseau on mankind. Hobbes believed man had a self-serving nature whereas Rousseau was more forgiving towards the nature of man, suggesting them to be noble and dignified. Hobbes saw the need for a governing intermediary to control this selfish nature which provided a basis for the exchange theory, and also links to Mcgregor’s Theory of X and Y, relevant to management literature. He also considered cooperation and competition, relevant to game theory as an explanation of man’s motives and can be used for understanding the exercising of power in marketing channels. Pinker outlines why the nature debate has been suppressed by the nurture debate in his book The Blank Slate.
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