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A1993KF42600001
A1993KF42600001

... This Week’s Citation Classic® ...
Modern Homo sapiens
Modern Homo sapiens

... First, mitochondrial DNA (DNA that is outside of the nucleus and inherited solely through the maternal line—mitochondria on sperm do not get incorporated into the zygote) calculations of difference between living people have been used to estimate how long it took these differences to evolve. Such da ...
Evolutionary Psych: Understanding Nature vs. Nurture
Evolutionary Psych: Understanding Nature vs. Nurture

... • Certain biological and behavioral variations increase an organism’s chance at survival in a certain environment and thus increase their chances for reproduction • Offspring from these organisms have a better chance at survival • Thus, their characteristics begin to become dominant in the overall p ...
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TODAY. . . Selection Directional Stabilizing Disruptive More HW

... • No allele is more fit than any other (no natural selection) – drift is random with respect to fitness • BUT, some alleles clearly “won” the reproduction lottery – They randomly increased their frequency in the population • In finite populations equally fit alleles are at risk of disappearing = los ...
Enduring understanding 1.A: Change in the genetic makeup of a
Enduring understanding 1.A: Change in the genetic makeup of a

... d. Environments can be more or less stable or fluctuating, and this affects evolutionary rate and direction; different genetic variations can be selected in each generation. e. An adaptation is a genetic variation that is favored by selection and is manifested as a trait that provides an advantage t ...
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... The founder effect can result if genes/alleles migrate from one population to another. Genes are lost in the original and added to the new population. If this migration happens multiple times it is called gene flow. If the same changes occur by chance it is called genetic drift. In any of these case ...
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Chapter 16 How Populations Evolve

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bandfeffect

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Chapter 16 Notes

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Genetics Selection and Genetic Drift

... certain trait disappears or appears in a population by chance and becomes common over time. The founder effect occurs when allele frequencies change as a result of the migration of a small subgroup of a population. ...
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... James Gusella and co-workers locate a genetic marker for Huntington’s disease on chromosome 4. This leads to scientists having the ability to screen people for a disease without being able ot cure it. Kary Mullis conceives of the polymerase chain reaction, a chemical DNA replication process that gr ...
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... living in one of the scariest times since life arose at least 3.7 billion years ago. Life on Earth today is being battered by massive habitat disruption, climate change, invasive species, foreign pathogens, pollution, overhunting, species extinctions and the disruption of entire ecological communiti ...
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91157 Demonstrate understanding of genetic variation and

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... identify variants that are found more often in people with a trait or disease than those without. This approach requires powerful analytical and statistical methods, many developed at the Broad Institute and shared openly with researchers around the world. However, correlation — in the form of assoc ...
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... • Genetic drift has been observed in some small human populations that have become isolated due to reasons such as religious practices and belief systems. • Genetic equilibrium is also disrupted by the movement of individuals in and out of a population. ...
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You and your Genes.

... and they find out their child has a genetic disease they could decide not to have the child. ...
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Week 5 - Cloudfront.net

... colonization by a limited number of individuals from a parent population – just by chance some rare alleles may be at high frequency; others may be missing – skew the gene pool of new population • human populations that started from small group of colonists • example: ...
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< 1 ... 503 504 505 506 507 508 509 510 511 ... 541 >

Human genetic variation



Human genetic variation is the genetic differences both within and among populations. There may be multiple variants of any given gene in the human population (genes), leading to polymorphism. Many genes are not polymorphic, meaning that only a single allele is present in the population: the gene is then said to be fixed. On average, in terms of DNA sequence all humans are 99.9% similar to any other humans.No two humans are genetically identical. Even monozygotic twins, who develop from one zygote, have infrequent genetic differences due to mutations occurring during development and gene copy-number variation. Differences between individuals, even closely related individuals, are the key to techniques such as genetic fingerprinting. Alleles occur at different frequencies in different human populations, with populations that are more geographically and ancestrally remote tending to differ more.Causes of differences between individuals include the exchange of genes during meiosis and various mutational events. There are at least two reasons why genetic variation exists between populations. Natural selection may confer an adaptive advantage to individuals in a specific environment if an allele provides a competitive advantage. Alleles under selection are likely to occur only in those geographic regions where they confer an advantage. The second main cause of genetic variation is due to the high degree of neutrality of most mutations. Most mutations do not appear to have any selective effect one way or the other on the organism. The main cause is genetic drift, this is the effect of random changes in the gene pool. In humans, founder effect and past small population size (increasing the likelihood of genetic drift) may have had an important influence in neutral differences between populations. The theory that humans recently migrated out of Africa supports this.The study of human genetic variation has both evolutionary significance and medical applications. It can help scientists understand ancient human population migrations as well as how different human groups are biologically related to one another. For medicine, study of human genetic variation may be important because some disease-causing alleles occur more often in people from specific geographic regions. New findings show that each human has on average 60 new mutations compared to their parents.Apart from mutations, many genes that may have aided humans in ancient times plague humans today. For example, it is suspected that genes that allow humans to more efficiently process food are those that make people susceptible to obesity and diabetes today.
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