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Chapter 4 Heredity and Evolution
Chapter 4 Heredity and Evolution

... Genetic drift in which allele frequencies are altered in small populations that are taken from, or are remnants of, larger populations. A new population will be established, and as long as mates are chosen only within this population, all the members will be descended from the founders. An allele th ...
Changes in DNA can produce variation
Changes in DNA can produce variation

... Base Pairs ...
Positive assortative mating
Positive assortative mating

... of populations is ignored), like inbreeding. ...
WELCOME BACK! Time to jump start your brain!
WELCOME BACK! Time to jump start your brain!

... • One of the benefits of sexual reproduction (over asexual reproduction) is that it provides for abundant variation. • There can be 8 million different combinations of chromosomes produced through meiosis. • Crossing over occurs when homologous chromosomes exchange segments during meiosis. ...
Zoology/Botany 345 Fall 1995
Zoology/Botany 345 Fall 1995

... 1. What are population bottlenecks? What evolutionary factor(s) (i.e., natural selection, genetic drift, mutation, migration or inbreeding) is important during a bottleneck? 2. What evidence suggests that there were two population bottlenecks in the cheetah? Do the data offer strong support for this ...
Independent Assortment of Chromosomes
Independent Assortment of Chromosomes

... Concept 10.4: Genetic variation produced in sexual life cycles contributes to evolution • Mutations (changes in an organism’s DNA) are the original source of genetic diversity • Mutations are what created different versions of genes called alleles • Reshuffling of alleles during sexual reproduction ...
Summary Gene regulatory factors in the evolutionary history of
Summary Gene regulatory factors in the evolutionary history of

... coagulation (STX1B and VKORC1) in humans. In addition, we also detected genetic changes at GRF sequence level that may have resulted in subtle regulatory changes in metabolic pathways associated with glucose and insulin metabolism at population-specific level. ...
Genetic Variation
Genetic Variation

... Natural Selection Theory Selective Pressure Environmental changes can cause pressure Organisms unable to adapt quickly enough will die Organisms that adapt are able to pass on their successful traits to future generations ...
Evolutionary Genetics Field Trip Survey Introduction Cepaea
Evolutionary Genetics Field Trip Survey Introduction Cepaea

... Since the 1940s, C. nemoralis has been used as a biological model species within the long held debate of selection versus genetic drift. It is an ideal species for this purpose due to its conspicuous polymorphism in both shell colour and number of bands. Individuals can easily be identified on site ...
Day 3 - Scott County Schools
Day 3 - Scott County Schools

... 5. _________ Biotechnology is also referred to as genetic engineering. 6. _________ The only use of biotechnology is curing genetic disorders. 7. _________ Eating GMOs has been shown to cause genetic disorders in people. ...
Genetic Association Studies
Genetic Association Studies

... DNA Variation • >99.9 % of the sequence is identical between any two chromosomes. - Compare maternal and paternal chromosome 1 in single person - Compare Y chromosomes between two unrelated males • Even though most of the sequence is identical between two chromosomes, since the genome sequence is s ...
evolution, heredity, and behavior
evolution, heredity, and behavior

... with new forms originating and others becoming extinct Evolutionary process is gradual and continual. New species arise through slow and steady environmental changes that gradually ‘perfect’ each species to its surroundings. Sudden, dramatic changes in environment challenges species ability to adapt ...
statgen4
statgen4

... combinations with the rest of the gene pool, these provide the raw material on which natural selection can act. ...
Chapter Outline
Chapter Outline

... become more and more different over time. e. The differences in the genetic makeup of two populations who do not migrate can result in reproductive isolation. 3. Small populations are more likely to show the effects of genetic drift. a. Genetic drift refers to changes in allele frequencies of a gene ...
Document
Document

... Genetic screening can detect genetic disorders. • Genetic screening involves the testing of DNA. – determines risk of having DMD or passing on a genetic disorder – used to detect specific genes or proteins – can detect some genes related to an increased risk of cancer – can detect some genes known t ...
9.6 Genetic Screening and Gene Therapy KEY CONCEPT treatments.
9.6 Genetic Screening and Gene Therapy KEY CONCEPT treatments.

... Genetic screening can detect genetic disorders. • Genetic screening involves the testing of DNA. – determines risk of having DMD or passing on a genetic disorder – used to detect specific genes or proteins – can detect some genes related to an increased risk of cancer – can detect some genes known t ...
Neanderthals in Tibet
Neanderthals in Tibet

... How would you demonstrate this hypothesis? ...
Epigenetics: Biologic Targets, Biomarkers and Role in Disease
Epigenetics: Biologic Targets, Biomarkers and Role in Disease

... Epigenetics: Biologic targets, Biomarkers and role in disease Epigenetics refers to the heritable changes in gene expression which are not associated with sequence changes. While genetic differences explain variation between species, and to some extent, the variation between individuals of each spec ...
Chapter 27 Bacteria
Chapter 27 Bacteria

... of DNA? (Refer back to Ch. 16) ...
Bacteria - sandsbiochem
Bacteria - sandsbiochem

... of DNA? (Refer back to Ch. 16) ...
Lecture 19 Evolution of Senescence
Lecture 19 Evolution of Senescence

... Association of FOXO3A variation with human longevity confirmed in German centenarians The human forkhead box O3A gene (FOXO3A) encodes an evolutionarily conserved key regulator of the insulin–IGF1 signaling pathway that is known to influence metabolism and lifespan in model organisms. A recent study ...
Genetics in Epidemiology - University of Pittsburgh
Genetics in Epidemiology - University of Pittsburgh

... • Is there evidence of familial aggregation of the disorder (phenotype)? – Is a positive family history an independent risk factor for the disorder? • For many chronic disorders, a positive family history is associated with odds ratios between 2-6 ...
Gene pool
Gene pool

...  Genetic drift can be due to: a. bottleneck effect – dramatic decrease in alleles b/c of major disaster ex. Hunting in 1890’s reduced one elephant seal pop. to ~20 indiv.  very little genetic variation  24 exact same proteins ...
Molecular Genetics
Molecular Genetics

... - Normal errors in DNA replication and repair and external factors, including radiation and reactive chemicals can cause random changes, mutations in the DNA. - Errors in mitosis or meiosis can result in changes in phenotype. - DNA mutations can be positive, negative, or neutral based on the effect ...
Evolution - gomezbiomccaskey
Evolution - gomezbiomccaskey

... species from one common ancestor; formation of a new species  Species- defined as a population or group of populations whose members can interbreed and produce FERTILE offspring ...
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Human genetic variation



Human genetic variation is the genetic differences both within and among populations. There may be multiple variants of any given gene in the human population (genes), leading to polymorphism. Many genes are not polymorphic, meaning that only a single allele is present in the population: the gene is then said to be fixed. On average, in terms of DNA sequence all humans are 99.9% similar to any other humans.No two humans are genetically identical. Even monozygotic twins, who develop from one zygote, have infrequent genetic differences due to mutations occurring during development and gene copy-number variation. Differences between individuals, even closely related individuals, are the key to techniques such as genetic fingerprinting. Alleles occur at different frequencies in different human populations, with populations that are more geographically and ancestrally remote tending to differ more.Causes of differences between individuals include the exchange of genes during meiosis and various mutational events. There are at least two reasons why genetic variation exists between populations. Natural selection may confer an adaptive advantage to individuals in a specific environment if an allele provides a competitive advantage. Alleles under selection are likely to occur only in those geographic regions where they confer an advantage. The second main cause of genetic variation is due to the high degree of neutrality of most mutations. Most mutations do not appear to have any selective effect one way or the other on the organism. The main cause is genetic drift, this is the effect of random changes in the gene pool. In humans, founder effect and past small population size (increasing the likelihood of genetic drift) may have had an important influence in neutral differences between populations. The theory that humans recently migrated out of Africa supports this.The study of human genetic variation has both evolutionary significance and medical applications. It can help scientists understand ancient human population migrations as well as how different human groups are biologically related to one another. For medicine, study of human genetic variation may be important because some disease-causing alleles occur more often in people from specific geographic regions. New findings show that each human has on average 60 new mutations compared to their parents.Apart from mutations, many genes that may have aided humans in ancient times plague humans today. For example, it is suspected that genes that allow humans to more efficiently process food are those that make people susceptible to obesity and diabetes today.
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