• Study Resource
  • Explore Categories
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
Computer Note
Computer Note

... GGT can also be used for selection. The widely used molecular marker techniques that were developed in the last decade have introduced a new, valuable source of data ( Tanksley 1993). Polymorphisms at the molecular level are widely used to analyze differences between individual plants, populations, ...
CHAPTER 13: Meiosis and Sexual Reproduction
CHAPTER 13: Meiosis and Sexual Reproduction

... 10. Summarize the significant differences between mitosis and meiosis. Mitosis ...
VI. CHROMOSOMAL BASIS OF INHERITANCE, cont
VI. CHROMOSOMAL BASIS OF INHERITANCE, cont

... • The gene for amber body color in Drosophila is sex-linked recessive. The dominant allele produces wild type body color. The gene for black eyes is autosomal recessive; the wild type red eyes are dominant. If males with amber bodies, heterozygous for eye color are crossed with females heterozygous ...
Genetic Disorders
Genetic Disorders

... Background: Sometimes genetic disorders are caused by mutations to normal genes. When the mutation has been in the population for a long enough amount of time, there is a greater chance that someone can be born with the disease. Procedure: (Dominant Genetic Disorder) Huntington’s disease is a geneti ...
Tibetan and Andean Patterns of Adaptation to High
Tibetan and Andean Patterns of Adaptation to High

... ling for environmental influences can reveal the influence of unknown genes. A shortcoming of this approach is the implicit assumption of genetic homogeneity at relevant loci in both samples and the explicit assumption that environmental sources of variation are known and uniform. Actually, many lo ...
Human Pedigrees - Downtown Magnets High School
Human Pedigrees - Downtown Magnets High School

... We now know that individual III:1 is a male. Occasionally, the sex of an individual may not be known. Common reasons for this would be, miscarriages or early death, babies given up for adoption, a child that has not been born yet, or distant family members.  These individuals can be noted by using ...
Variation and its response to selection
Variation and its response to selection

... •CV allows comparison of variability of traits of very different sizes •Organisms showing determinate growth show restricted CV: •Birds have a CV of 2-4% for most traits •Microtus voles have a CV of about 10 % for body weight •CVs may be larger for organisms with indeterminate growth (e.g. fish) ...
Document
Document

... Inbreeding • Inbreeding = mating of related individuals • Often results in a change in the mean of a trait • Inbreeding is intentionally practiced to: – create genetic uniformity of laboratory stocks – produce stocks for crossing (animal and plant breeding) • Inbreeding is unintentionally generated ...
Chapter 2: Introduction to Molecular Genetics
Chapter 2: Introduction to Molecular Genetics

...  For RNA, uracil (U) is substituted for thymine in DNA.  There are about 20,000 genes for humans  Genes vary enormously in length from less than a thousand base (Kb) pairs to over a million base pairs (Mb) ...
Evaluation of current methods performing in Preimplantation Genetic
Evaluation of current methods performing in Preimplantation Genetic

... signals for each chromatid. Adapted from "Aneuploidy study of human oocytes first polar body comparative genomic hybridization and metaphase II fluorescence in situ hybridization analysis." by Gutierrez-Mateo, C., J. Benet, et al., Hum. Reprod. 19(12): 2859-2868. Like SKY and other methods, FISH dep ...
biology i honors capacity matrix unit vii: genetics
biology i honors capacity matrix unit vii: genetics

... expresses a desired trait. Genetic engineering is accomplished by taking specific genes from one organism and placing them into another organism.  Genetic engineering can only occur when scientists know exactly where particular genes for particular traits occur on specific chromosomes. o A gene map ...
An Overview of Evolutionary Computation
An Overview of Evolutionary Computation

... is no a priori reason (other than convenience) to make this assumption. We will discuss the issue of a dynamic population size later in this paper. An evolutionary algorithm typically initializes its population randomly, although domain specific knowledge can also be used to bias the search. Evaluat ...
Identifying and Controlling Defective Genes.
Identifying and Controlling Defective Genes.

... unapparent carrier individuals. For some genetic disorders, biochemical tests can be done to identify carriers of recessive genes. If the gene "codes" for the production of an enzyme or biochemical substance necessary for normal metabolism, carriers (those with only one normal gene) will have approx ...
Review Towards genetic manipulation of wild mosquito populations
Review Towards genetic manipulation of wild mosquito populations

... The fitness cost of refractoriness To maximize the likelihood of successfully introducing refractory genes into a wild mosquito population, transgenes should impose minimal fitness load. We assessed fitness of transgenic An. stephensi expressing the SM1 and the PLA2 transgenes by a variety of criter ...
1.1 Genetic terms you should know and understand Mendelian
1.1 Genetic terms you should know and understand Mendelian

... represent the abnormality if it is dominant or recessive, respectively. Parents connected by horizontal lines. Vertical lines lead to their offspring. Try the possible models one by one. 1. If the abnormality were due to a dominant mutation in a gene on an autosome (autosomal dominant): A - dominan ...
Nonadaptive processes in primate and human evolution
Nonadaptive processes in primate and human evolution

... Humans and chimpanzees are very similar when protein-coding portions of their genomes are compared. Mikkelsen et al. (2005) found that they are identical at 29% of proteins, and, at the remaining 71%, they differ to a very small degree, at only one or two amino acid sites. Using such observations, i ...
Obstructive sleep apnea syndrome (OSAS) in children with Class III
Obstructive sleep apnea syndrome (OSAS) in children with Class III

... patients (32 %) and never in controls (0 %), leads us to search for an etiologic meaning. Our idea is supported by recent literature. A number of studies over the last years have in fact questioned this assumption, asserting that silent mutations can be implicated in diseases [33–36]. Kimchi-Sarfaty ...
the x chromosome in population genetics
the x chromosome in population genetics

... in which it is being studied (BOX 1; TABLE 1). In this context, what does the mammalian X chromosome look like? In many respects, it looks very similar to an autosome, which is not surprising given its history. The two sex chromosomes, the X and the Y, diverged from a single autosome ~300 million ye ...
6.6 Selection: Winning and Losing
6.6 Selection: Winning and Losing

... if a mutationwith beneficialeffectsfor one trait alsocauses detrimentaleffectson other traits. ...
Novel visual system homeobox 1 gene mutations in Turkish patients
Novel visual system homeobox 1 gene mutations in Turkish patients

... of these results in other KC families and patients (Davidson et al., 2014). Genome-wide association studies (GWAS) are a powerful tool to investigate the genetic factors of complex traits and diseases like KC (Li et al., 2012; Cuellar-Partida et al., 2015). Previous GWAS conducted on both European a ...
Horizontal gene transfer and bacterial diversity
Horizontal gene transfer and bacterial diversity

... In any chromosome, ancestral (vertically transmitted) genes experience a particular set of directional mutation pressures (Sueoka 1988), mediated by the specific features of the replication machinery of the cell, such as the balance of the dNTP pools, mutational biases of the DNA polymerases, effici ...
Genetic recombination and mutations - formatted
Genetic recombination and mutations - formatted

... any changes, the alterations are relative to “wild type (most widely occurring)” nucleotide sequence or chromosomal structure. Mutations usually arise due to the errors that occur during the replication process and are retained or carried forward if not rectified. The chance that a mutation occurs i ...
Motion - TPAYNTER
Motion - TPAYNTER

... Any change in the allelic frequencies in a population that results from chance is called genetic drift. In smaller populations, the effects of genetic drift become more pronounced, and the chance of losing an allele becomes greater. ...
Are you your grandmother`s favorite
Are you your grandmother`s favorite

... male or a female. Thus, the transmission likelihood for any particular X-linked gene is 0.5 inheritance from MGM to mother, and 0.5 from mother to child. Therefore, the likelihood of a grandchild inheriting any particular gene from the MGM is 25 per cent (0.5 ! 0.5 ¼ 0.25). It is worth noting that f ...
A framework for describing genetic diseases
A framework for describing genetic diseases

... new mutations in gametes (usually point mutations, and usually in sperm from fathers age 35 and older). The predominance of spontaneous mutation in achondroplasia stems from the fact that this disease inhibits reproductive success and that the gene involved has a mutation rate higher than the averag ...
< 1 ... 116 117 118 119 120 121 122 123 124 ... 541 >

Human genetic variation



Human genetic variation is the genetic differences both within and among populations. There may be multiple variants of any given gene in the human population (genes), leading to polymorphism. Many genes are not polymorphic, meaning that only a single allele is present in the population: the gene is then said to be fixed. On average, in terms of DNA sequence all humans are 99.9% similar to any other humans.No two humans are genetically identical. Even monozygotic twins, who develop from one zygote, have infrequent genetic differences due to mutations occurring during development and gene copy-number variation. Differences between individuals, even closely related individuals, are the key to techniques such as genetic fingerprinting. Alleles occur at different frequencies in different human populations, with populations that are more geographically and ancestrally remote tending to differ more.Causes of differences between individuals include the exchange of genes during meiosis and various mutational events. There are at least two reasons why genetic variation exists between populations. Natural selection may confer an adaptive advantage to individuals in a specific environment if an allele provides a competitive advantage. Alleles under selection are likely to occur only in those geographic regions where they confer an advantage. The second main cause of genetic variation is due to the high degree of neutrality of most mutations. Most mutations do not appear to have any selective effect one way or the other on the organism. The main cause is genetic drift, this is the effect of random changes in the gene pool. In humans, founder effect and past small population size (increasing the likelihood of genetic drift) may have had an important influence in neutral differences between populations. The theory that humans recently migrated out of Africa supports this.The study of human genetic variation has both evolutionary significance and medical applications. It can help scientists understand ancient human population migrations as well as how different human groups are biologically related to one another. For medicine, study of human genetic variation may be important because some disease-causing alleles occur more often in people from specific geographic regions. New findings show that each human has on average 60 new mutations compared to their parents.Apart from mutations, many genes that may have aided humans in ancient times plague humans today. For example, it is suspected that genes that allow humans to more efficiently process food are those that make people susceptible to obesity and diabetes today.
  • studyres.com © 2026
  • DMCA
  • Privacy
  • Terms
  • Report