THE EFFECT OF R-FACTOR CARRIAGE ON THE SURVIVAL O F
... pseudomonads has been shown to be mediated by these plasmids. However, the fear that all organisms capable of R-factor transfer might become solidly resistant to all antibiotics has not been realised. Indeed, recent evidence suggests that the incidence of antibiotic-resistant organisms may have leve ...
... pseudomonads has been shown to be mediated by these plasmids. However, the fear that all organisms capable of R-factor transfer might become solidly resistant to all antibiotics has not been realised. Indeed, recent evidence suggests that the incidence of antibiotic-resistant organisms may have leve ...
Touring Ensembl: A practical guide to genome browsing Open Access
... script for IL2, and align with regulatory regions, indicating regions of high sequence conservation and thus, possible function. A third track displays data from 'CisRED'[27] a database of patterns and motifs associated with regulatory regions, 'miRanda'[28] a collection of miRNA targets identified ...
... script for IL2, and align with regulatory regions, indicating regions of high sequence conservation and thus, possible function. A third track displays data from 'CisRED'[27] a database of patterns and motifs associated with regulatory regions, 'miRanda'[28] a collection of miRNA targets identified ...
milova_032405 - Microarray Facility
... Gene Ontology annotation for all GO IDs is kept in three different information fields: biological processes, molecular function and cellular compartment. For each of the fields all available annotation was prefiltered with redundancy check and concatenated. Kate Milova ...
... Gene Ontology annotation for all GO IDs is kept in three different information fields: biological processes, molecular function and cellular compartment. For each of the fields all available annotation was prefiltered with redundancy check and concatenated. Kate Milova ...
Whose Genetic Information Is It Anyway?
... www.health.state.mn.us/htacgt.htm> (June 1998). The genes BRCA1 and BRCA 2 were identified as playing a role in the development of breast cancer in 1994. Id. When these genes are performing regularly in the human body, they help the body to suppress cancer. Id. However, when a mutation in either of ...
... www.health.state.mn.us/htacgt.htm> (June 1998). The genes BRCA1 and BRCA 2 were identified as playing a role in the development of breast cancer in 1994. Id. When these genes are performing regularly in the human body, they help the body to suppress cancer. Id. However, when a mutation in either of ...
Biological interpretation of genome-wide association studies using
... phenotype3). The paradigm for gene set analysis is to search for enrichment of the genes near associated variants in manually curated gene sets or in gene sets derived from molecular evidence4. Although certain pathways have been carefully characterized, and manually curated gene sets and protein– p ...
... phenotype3). The paradigm for gene set analysis is to search for enrichment of the genes near associated variants in manually curated gene sets or in gene sets derived from molecular evidence4. Although certain pathways have been carefully characterized, and manually curated gene sets and protein– p ...
Structural Domains and Matrix Attachment Regions
... a molecular basis for renewing our pursuit of a possible relationship between gene structure and function. Although some limitations of our analysis and screening approach, at that time, have been acknowledged and discussed (Avramova et al., 1995), most of them have now been overcome, as described b ...
... a molecular basis for renewing our pursuit of a possible relationship between gene structure and function. Although some limitations of our analysis and screening approach, at that time, have been acknowledged and discussed (Avramova et al., 1995), most of them have now been overcome, as described b ...
... Database searches revealed that the AN2 protein is similar to a range of so-called MYB domain proteins from animals and plants. Parsimony analysis showed that, in general, AN2 is more related to plant MYB proteins than to the animal c-MYB, the prototype of this superfamily (Figure 3A). The protein w ...
Characterization of the neurohypophysial hormone gene loci in
... Neurohypophysial hormones are an ancient family of structurally and functionally related nonapeptides, with representatives found in deuterostomes as well as in protostomes. Vasopressin and oxytocin are mammalian neurohypophysial hormones with distinct activities: vasopressin has renal urine reabsor ...
... Neurohypophysial hormones are an ancient family of structurally and functionally related nonapeptides, with representatives found in deuterostomes as well as in protostomes. Vasopressin and oxytocin are mammalian neurohypophysial hormones with distinct activities: vasopressin has renal urine reabsor ...
RNA and Protein Synthesis
... that consists of a long chain of nucleotides. In a general way, genes contain coded DNA instructions that tell cells how to build proteins. The first step in decoding these genetic instructions is to copy part of the base sequence from DNA into RNA. RNA then uses these instructions to direct the prod ...
... that consists of a long chain of nucleotides. In a general way, genes contain coded DNA instructions that tell cells how to build proteins. The first step in decoding these genetic instructions is to copy part of the base sequence from DNA into RNA. RNA then uses these instructions to direct the prod ...
A xylem-specific cellulose synthase gene from aspen (Populus
... additional plant CesA genes. Arioli et al. (1998) and Taylor et al. (1999) then mapped and cloned the Arabidopsis CesA homologs RSW1 and IRX3. Complementation of rsw1 and irx3 mutants with wild-type RSW1 and IRX3 genes, respectively, restored the wild-type phenotype, providing genetic proof of the i ...
... additional plant CesA genes. Arioli et al. (1998) and Taylor et al. (1999) then mapped and cloned the Arabidopsis CesA homologs RSW1 and IRX3. Complementation of rsw1 and irx3 mutants with wild-type RSW1 and IRX3 genes, respectively, restored the wild-type phenotype, providing genetic proof of the i ...
Evolution-Based Deliberative Planning for Cooperating UGV`s in a
... domain-specific evaluation component that computes a single term in a fitness function. Each tactical critic evaluates how well a given operation plan satisfies a tactical criterion. For instance, a critic for safety may evaluate a plan to determine how much danger the UGVs are placed in due to trav ...
... domain-specific evaluation component that computes a single term in a fitness function. Each tactical critic evaluates how well a given operation plan satisfies a tactical criterion. For instance, a critic for safety may evaluate a plan to determine how much danger the UGVs are placed in due to trav ...
NIH Public Access
... A recent study demonstrated that DME is necessary for demethylation and transcriptional activation of the maternal MEA in the endosperm [5••]. DME encodes a DNA glycosylase that specifically removes 5-methylcytosine from DNA [5••,18]. DNA glycosylases are repair enzymes that initiate the base excisi ...
... A recent study demonstrated that DME is necessary for demethylation and transcriptional activation of the maternal MEA in the endosperm [5••]. DME encodes a DNA glycosylase that specifically removes 5-methylcytosine from DNA [5••,18]. DNA glycosylases are repair enzymes that initiate the base excisi ...
Research Project Final Report
... optimise the crop. In addition there are the tools and resources available in B. oleracea to exploit genetic variation for important input traits such as nitrogen, phosphorous and water use efficiency as well as pest and disease resistance. It is therefore possible to ‘design’ and breed to an ideoty ...
... optimise the crop. In addition there are the tools and resources available in B. oleracea to exploit genetic variation for important input traits such as nitrogen, phosphorous and water use efficiency as well as pest and disease resistance. It is therefore possible to ‘design’ and breed to an ideoty ...
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... pulmonary obstruction measurement and one of the most significant predictors for chronic obstructive pulmonary disease (COPD), which is a heritable multi-factorial disease. We present genome-wide association study (GWAS) to map the genetic architecture of this trait and investigate the networks betw ...
... pulmonary obstruction measurement and one of the most significant predictors for chronic obstructive pulmonary disease (COPD), which is a heritable multi-factorial disease. We present genome-wide association study (GWAS) to map the genetic architecture of this trait and investigate the networks betw ...
Genetics of Hemophilia
... »» Women who are carriers may experience bleeding symptoms, as they may have factor levels low enough to be in the mild range of deficiency. Females who carry hemophilia should have their factor (VIII or IX) levels checked to ensure they have adequate levels for normal blood clotting. See the “Hemop ...
... »» Women who are carriers may experience bleeding symptoms, as they may have factor levels low enough to be in the mild range of deficiency. Females who carry hemophilia should have their factor (VIII or IX) levels checked to ensure they have adequate levels for normal blood clotting. See the “Hemop ...
array CGH - Unique The Rare Chromosome Disorder Support Group
... (where a section of a chromosome is inverted or reversed), will not be identified using array CGH. This is because balanced chromosome rearrangements do not result in any loss or gain of chromosome material. It will also not detect some types of polyploidy (more than the usual 2 sets of chromosomes) ...
... (where a section of a chromosome is inverted or reversed), will not be identified using array CGH. This is because balanced chromosome rearrangements do not result in any loss or gain of chromosome material. It will also not detect some types of polyploidy (more than the usual 2 sets of chromosomes) ...
Informed Consent for Prenatal Diagnosis by
... the chromosome analysis. Very small differences in the chromosomes may be missed. There is also a small chance that mother’s cells can get into the sample, which may make it difficult to get accurate results. 8) I understand that before and during the amniocentesis, ultrasound will be used to examin ...
... the chromosome analysis. Very small differences in the chromosomes may be missed. There is also a small chance that mother’s cells can get into the sample, which may make it difficult to get accurate results. 8) I understand that before and during the amniocentesis, ultrasound will be used to examin ...
Genetics of allergic disease
... be genetic heterogeneity. This means that in different populations, separate genes act in the regulation of these phenotypes. To date, this cannot be investigated since the exact locations of these genes are still unknown. Using a single locus approach, the best fitting models for high serum IgE lev ...
... be genetic heterogeneity. This means that in different populations, separate genes act in the regulation of these phenotypes. To date, this cannot be investigated since the exact locations of these genes are still unknown. Using a single locus approach, the best fitting models for high serum IgE lev ...
Linkage Mapping 2 3 – point linkage mapping One crossover Two
... • Any number of crossovers greater than zero will produce 50% recombinant gametes on average. • This is why recombination frequency is not a linear function of the average number of crossovers between two loci. • If loci are widely separated on the chromosome, several crossovers may occur between th ...
... • Any number of crossovers greater than zero will produce 50% recombinant gametes on average. • This is why recombination frequency is not a linear function of the average number of crossovers between two loci. • If loci are widely separated on the chromosome, several crossovers may occur between th ...
08_chapter 1
... 1.2.2.2. Inversion and inverted transposition hypothesis There are two independent publIcations suggesting genome wide inversions are responsible for the establishment of parity in chromosomes (Albrecht-Buehler, 2006; Okamura et at., 2007). Albrecht-Buehler (2006) has viewed Chargaffs 2 nd parity as ...
... 1.2.2.2. Inversion and inverted transposition hypothesis There are two independent publIcations suggesting genome wide inversions are responsible for the establishment of parity in chromosomes (Albrecht-Buehler, 2006; Okamura et at., 2007). Albrecht-Buehler (2006) has viewed Chargaffs 2 nd parity as ...
Extrachromosomal DNA Transformationof Caenorhabditis elegans
... Thus, methods for stably introducing DNA into single cells provide a new window into the' molecular mechanisms of cellular behavior. Similarly, techniques for DNA transformation of multicellular organisms facilitate the molecular analysis of developmental processes. DNA transformation of multicellul ...
... Thus, methods for stably introducing DNA into single cells provide a new window into the' molecular mechanisms of cellular behavior. Similarly, techniques for DNA transformation of multicellular organisms facilitate the molecular analysis of developmental processes. DNA transformation of multicellul ...
Analysis of 16S ribosomal RNA gene segments for the diagnosis of
... as an alternative or complement to established phenotypic methods. Typically, genotypic identification of bacteria involves the use of conserved sequences within phylogenetically informative genetic targets, such as the small-subunit 16S-rRNA gene (Wilson et al., 1990; Woese et al., 1990; Kirschner ...
... as an alternative or complement to established phenotypic methods. Typically, genotypic identification of bacteria involves the use of conserved sequences within phylogenetically informative genetic targets, such as the small-subunit 16S-rRNA gene (Wilson et al., 1990; Woese et al., 1990; Kirschner ...
Petunia Ap2-like Genes and Their Role in Flower and
... signal was observed in the procambial cells of the developing stem. In bracts subtending stage 4 to 5 flower buds and in stage 6 sepals, the PhAp2A mRNA was not distributed uniformly but localized to a layer of ground parenchyma cells (Figure 2B). The expression of PhAp2A in sepals and bracts decrea ...
... signal was observed in the procambial cells of the developing stem. In bracts subtending stage 4 to 5 flower buds and in stage 6 sepals, the PhAp2A mRNA was not distributed uniformly but localized to a layer of ground parenchyma cells (Figure 2B). The expression of PhAp2A in sepals and bracts decrea ...
Lyons/Hewitt/Suchocki/Yeh, CONCEPTUAL INTEGRATED SCIENCE
... The Human Genome The human genome consists of 23 pairs of chromosomes. The Human Genome Project sequenced the entire human genome. Over 99.9% of the 3 billion base pairs in the human genome are identical in all humans. Copyright © 2007 Pearson Education, Inc., publishing as Pearson Addison-Wesley ...
... The Human Genome The human genome consists of 23 pairs of chromosomes. The Human Genome Project sequenced the entire human genome. Over 99.9% of the 3 billion base pairs in the human genome are identical in all humans. Copyright © 2007 Pearson Education, Inc., publishing as Pearson Addison-Wesley ...
Genetic engineering
Genetic engineering, also called genetic modification, is the direct manipulation of an organism's genome using biotechnology. It is therefore a set of technologies used to change the genetic makeup of cells, including the transfer of genes within and across species boundaries to produce improved or novel organisms. New DNA may be inserted in the host genome by first isolating and copying the genetic material of interest using molecular cloning methods to generate a DNA sequence, or by synthesizing the DNA, and then inserting this construct into the host organism. Genes may be removed, or ""knocked out"", using a nuclease. Gene targeting is a different technique that uses homologous recombination to change an endogenous gene, and can be used to delete a gene, remove exons, add a gene, or introduce point mutations.An organism that is generated through genetic engineering is considered to be a genetically modified organism (GMO). The first GMOs were bacteria generated in 1973 and GM mice in 1974. Insulin-producing bacteria were commercialized in 1982 and genetically modified food has been sold since 1994. Glofish, the first GMO designed as a pet, was first sold in the United States December in 2003.Genetic engineering techniques have been applied in numerous fields including research, agriculture, industrial biotechnology, and medicine. Enzymes used in laundry detergent and medicines such as insulin and human growth hormone are now manufactured in GM cells, experimental GM cell lines and GM animals such as mice or zebrafish are being used for research purposes, and genetically modified crops have been commercialized.