Determination of IL-23 receptor gene polymorphism in Iranian
... the most common genetic factor involved in the initiation and pathology of this disease. It is estimated that up to 90% of patients with AS could be HLA-B27-positive in most ethnic populations throughout the world; however, only 2% of HLA-B27-positive individuals in the general populations could be ...
... the most common genetic factor involved in the initiation and pathology of this disease. It is estimated that up to 90% of patients with AS could be HLA-B27-positive in most ethnic populations throughout the world; however, only 2% of HLA-B27-positive individuals in the general populations could be ...
Category 2000
... Our objective was to develop straightforward methods to examine the two loci in swine breeds from Romania. We used the PCR-RFLP technique to identify two point mutations: one for RYR1 gene (C T) correlated with malignant hyperthermia and another for ESR gene (T G) associated with reproduction traits ...
... Our objective was to develop straightforward methods to examine the two loci in swine breeds from Romania. We used the PCR-RFLP technique to identify two point mutations: one for RYR1 gene (C T) correlated with malignant hyperthermia and another for ESR gene (T G) associated with reproduction traits ...
HLRCC Science
... so that half the DNA goes to each of the two new cells. Later, each cell replicates the DNA it has received. During this process of cell division and DNA replication, mistakes can be made. Mistakes can also occur when DNA is damaged by radiation, sunlight and chemicals. Often the cells can repair da ...
... so that half the DNA goes to each of the two new cells. Later, each cell replicates the DNA it has received. During this process of cell division and DNA replication, mistakes can be made. Mistakes can also occur when DNA is damaged by radiation, sunlight and chemicals. Often the cells can repair da ...
the Liver - Saudi Medical Journal
... of Th1 cytokines to RSA or multiple implantation failures in IVF cycles (19) . We have used these strategies to examine associations between maternal carriage of cytokine polymorphisms and RSA by investigating certain genetic polymorphism in the promoter region of TNF-α, IL-10 and IL-6 gene in Saudi ...
... of Th1 cytokines to RSA or multiple implantation failures in IVF cycles (19) . We have used these strategies to examine associations between maternal carriage of cytokine polymorphisms and RSA by investigating certain genetic polymorphism in the promoter region of TNF-α, IL-10 and IL-6 gene in Saudi ...
P-Element Transformation with period Locus DNA Restores
... and mapped to the 3B1-2 region of the X chromosome (e.g., Smith and Konopka, 1981). We and others have begun molecular analysis of the per region (Reddy et al., 1984; Bargiello and Young, 1984). Some of our previous findings are summarized in Figure IA, including the molecularly mapped sites of cert ...
... and mapped to the 3B1-2 region of the X chromosome (e.g., Smith and Konopka, 1981). We and others have begun molecular analysis of the per region (Reddy et al., 1984; Bargiello and Young, 1984). Some of our previous findings are summarized in Figure IA, including the molecularly mapped sites of cert ...
FRIZZY PANICLE Drives Supernumerary
... electron microscopy analysis; O.D. carried out resequencing; E.S. contributed to the writing of the article; O.D. and J.S. wrote the article with input from all the coauthors; O.D. and J.S. managed the project. www.plantphysiol.org/cgi/doi/10.1104/pp.114.250043 ...
... electron microscopy analysis; O.D. carried out resequencing; E.S. contributed to the writing of the article; O.D. and J.S. wrote the article with input from all the coauthors; O.D. and J.S. managed the project. www.plantphysiol.org/cgi/doi/10.1104/pp.114.250043 ...
Bacterial evolution and the cost of antibiotic resistance
... hosts with both the ancestral and evolved plasmids, giving four genotypes: B0/P0, B0/P500, B500/P0, and B500/P500, where B and P denote the bacteria and plasmid, respectively, and subscripts 0 and 500 indicate the ancestral (naive) and evolved forms, respectively. Each of these genotypes was placed ...
... hosts with both the ancestral and evolved plasmids, giving four genotypes: B0/P0, B0/P500, B500/P0, and B500/P500, where B and P denote the bacteria and plasmid, respectively, and subscripts 0 and 500 indicate the ancestral (naive) and evolved forms, respectively. Each of these genotypes was placed ...
Targeted gene inactivation in Clostridium phytofermentans shows
... phytofermentans. Efficient transfer of DNA into C. phytofermentans is achieved by conjugation with E. coli expressing the broad host range RP4 conjugal apparatus. Conjugation has been used transfer plasmids to several mesophilic clostridia including C. acetobutylicum (Williams et al., 1990), C. perf ...
... phytofermentans. Efficient transfer of DNA into C. phytofermentans is achieved by conjugation with E. coli expressing the broad host range RP4 conjugal apparatus. Conjugation has been used transfer plasmids to several mesophilic clostridia including C. acetobutylicum (Williams et al., 1990), C. perf ...
Becker Muscular Dystrophy (BMD)
... What are genes and chromosomes? Genes are the unique set of instructions inside our bodies which makes each of us individual. There are many thousands of different genes, each carrying a different instruction. As well as determining how we look, our genes control the way each cell or building block ...
... What are genes and chromosomes? Genes are the unique set of instructions inside our bodies which makes each of us individual. There are many thousands of different genes, each carrying a different instruction. As well as determining how we look, our genes control the way each cell or building block ...
- Journal of Clinical Investigation
... He noted that the embryos of the zebrafish are transparent, and that fertilization is external, so that all stages of development are accessible. Development is rapid, with a heart beating by the end of the first day and most organs, or at least their primordia, in place by five days after fertiliza ...
... He noted that the embryos of the zebrafish are transparent, and that fertilization is external, so that all stages of development are accessible. Development is rapid, with a heart beating by the end of the first day and most organs, or at least their primordia, in place by five days after fertiliza ...
Phenotypic and Genotypic Comparisons among Strains of the
... Guanine plus cytosine (G+C) content of DNA was determined by thermal denaturation (15), with 0 . 5 ~standard saline citrate (SSC) ( l x SSC is 0.15 M NaCl plus 0.015 M sodium citrate) as the solvent and DNA at concentrations corresponding to initial A260 of 0.4 to 0.7, representing 20 to 35 pg of DN ...
... Guanine plus cytosine (G+C) content of DNA was determined by thermal denaturation (15), with 0 . 5 ~standard saline citrate (SSC) ( l x SSC is 0.15 M NaCl plus 0.015 M sodium citrate) as the solvent and DNA at concentrations corresponding to initial A260 of 0.4 to 0.7, representing 20 to 35 pg of DN ...
to the complete text - David Moore`s World of Fungi
... thousand, if we want to obtain a believable result. But there is a better way. Much more information is obtained from a cross if three rather than two genetic markers are followed. In three-point crosses, recombination frequencies are obtained in the usual way but they also allow the relative order ...
... thousand, if we want to obtain a believable result. But there is a better way. Much more information is obtained from a cross if three rather than two genetic markers are followed. In three-point crosses, recombination frequencies are obtained in the usual way but they also allow the relative order ...
Genetics of Skin Colour
... While molecular and genetic studies have shown a variety of changes in many genes associated with skin colour variations, it is important to prove that they function to produce that particular variation. Currently, research suggests that functional variants in more than twenty known genes determine ...
... While molecular and genetic studies have shown a variety of changes in many genes associated with skin colour variations, it is important to prove that they function to produce that particular variation. Currently, research suggests that functional variants in more than twenty known genes determine ...
Chapter 1 Introduction to Evolutionary Computation and Genetic
... variety of classical optimization techniques, discovered that altering physical variables in a random manner (ensuring small modifications were more frequent than larger ones) proved to be a very effective technique. This gave rise to a form of evolutionary algorithm that they termed an evolutionary ...
... variety of classical optimization techniques, discovered that altering physical variables in a random manner (ensuring small modifications were more frequent than larger ones) proved to be a very effective technique. This gave rise to a form of evolutionary algorithm that they termed an evolutionary ...
F 1 - OpenWetWare
... Concept 8.2 Allleles and Genes Interact To Produce Phenotypes The search for a true-breeding palomino A golden horse with a white mane and tail is known as a palomino. For many years the genetics of this color was a mystery. Suppose you’ve been hired by a horse breeder who wants to produce a line o ...
... Concept 8.2 Allleles and Genes Interact To Produce Phenotypes The search for a true-breeding palomino A golden horse with a white mane and tail is known as a palomino. For many years the genetics of this color was a mystery. Suppose you’ve been hired by a horse breeder who wants to produce a line o ...
Machine Evolution - 서울대 Biointelligence lab
... Genetic and Evolutionary Computation Conference (GECCO) Parallel Problem Solving from Nature (PPSN) Int. Conf. on Artificial Neural Networks and Genetic Algorithms ...
... Genetic and Evolutionary Computation Conference (GECCO) Parallel Problem Solving from Nature (PPSN) Int. Conf. on Artificial Neural Networks and Genetic Algorithms ...
Gene prediction and Genome Annotation
... Gene finding –similarity based• Not much prediction, sensu strictu • Restricted to what can be aligned • Only possible when (closely) related gene and genome sequences exist • or entirely dependent on EST (cDNA) or RNASeq • Will not ‘predict’ fast evolving genes or ‘new’ genes • No need for trainin ...
... Gene finding –similarity based• Not much prediction, sensu strictu • Restricted to what can be aligned • Only possible when (closely) related gene and genome sequences exist • or entirely dependent on EST (cDNA) or RNASeq • Will not ‘predict’ fast evolving genes or ‘new’ genes • No need for trainin ...
Genetic linkage studies in the pseudoautosomal
... The importance of human genetics research is clear in order to understand human nature, diseases and development of effective disease treatment. Human genetics covers a variety of overlapping fields including cytogenetics, molecular genetics, population genetics, human biology, medical genetics and ...
... The importance of human genetics research is clear in order to understand human nature, diseases and development of effective disease treatment. Human genetics covers a variety of overlapping fields including cytogenetics, molecular genetics, population genetics, human biology, medical genetics and ...
Identification, cloning and sequence determination of genes specifying hexokinase A and B from yeast.
... concentration of 70 mM sodium phosphate which had a fructose/glucose activity ratio of 1.1, characteristic of hexokinase B. These experiments sufficed to show that each of the two genes represented by these classes of plasmid clones specifies one of the hexokinase isozymes. Additional evidence for t ...
... concentration of 70 mM sodium phosphate which had a fructose/glucose activity ratio of 1.1, characteristic of hexokinase B. These experiments sufficed to show that each of the two genes represented by these classes of plasmid clones specifies one of the hexokinase isozymes. Additional evidence for t ...
Functional SNPs in the SCGB3A2 promoter are
... is the production of thyroid-stimulating hormone receptor (TSHR)-stimulating antibodies, leading to hyperthyroidism. GD is a complex trait disease and develops in genetically susceptible individuals, which arises through the interactions of susceptibility genes (3) and non-genetic factors, such as i ...
... is the production of thyroid-stimulating hormone receptor (TSHR)-stimulating antibodies, leading to hyperthyroidism. GD is a complex trait disease and develops in genetically susceptible individuals, which arises through the interactions of susceptibility genes (3) and non-genetic factors, such as i ...
Prevention of DNA Rereplication Through a Meiotic Recombination
... of Cdk1 at tyrosine 19 (Leu and Roeder 1999). Early work in mitotic cells indicated that Swe1catalyzed Cdk1 phosphorylation regulates the morphogenesis checkpoint (Lew and Reed 1995). However, it is now known that Swe1 is also a component of one of three Mec1-dependent mechanisms that operate in t ...
... of Cdk1 at tyrosine 19 (Leu and Roeder 1999). Early work in mitotic cells indicated that Swe1catalyzed Cdk1 phosphorylation regulates the morphogenesis checkpoint (Lew and Reed 1995). However, it is now known that Swe1 is also a component of one of three Mec1-dependent mechanisms that operate in t ...
Mendel`s Genes: Toward a Full Molecular Characterization
... the mutation would have been much less instructive. It turns out also that Mendel’s LE gene is regulated by auxin (O’Neill et al. 2010; Ross and Reid 2010), another hormone of historical interest, and arguably the most studied of the plant growth substances. Interestingly, even though gibberellins a ...
... the mutation would have been much less instructive. It turns out also that Mendel’s LE gene is regulated by auxin (O’Neill et al. 2010; Ross and Reid 2010), another hormone of historical interest, and arguably the most studied of the plant growth substances. Interestingly, even though gibberellins a ...
The Mobile Genetic Element Alu in the Human Genome
... enetic material has been traditionally envisioned as relatively static with the exception of occasional, often deleterious mutations. The sequence DNA-toRNA-to-protein represented for many years the central dogma relating gene structure and function. Recently, the field of molecular genetics has pro ...
... enetic material has been traditionally envisioned as relatively static with the exception of occasional, often deleterious mutations. The sequence DNA-toRNA-to-protein represented for many years the central dogma relating gene structure and function. Recently, the field of molecular genetics has pro ...
Molecular Evolution of Functional Nucleic Acids
... specific to the keratinocyte growth factor (KGF) from two libraries of modified RNA, which contained either 2'-fluoropyrimidine nucleosides or 2'-aminopyrimidine nucleosides, and compared both the aptamers [59]. In this case, the 2'-fluoro modified RNA aptamer showed excellent binding affinity with ...
... specific to the keratinocyte growth factor (KGF) from two libraries of modified RNA, which contained either 2'-fluoropyrimidine nucleosides or 2'-aminopyrimidine nucleosides, and compared both the aptamers [59]. In this case, the 2'-fluoro modified RNA aptamer showed excellent binding affinity with ...
Standard Seven: Diversity and Continuity of living Things 5/9/05
... sections of DNA that direct syntheses of specific proteins associated with traits in organisms. These consist of various combinations of four different nucleotides that encode this information through their sequences. 2. Known patterns of inheritance can be used to make predictions about genetic var ...
... sections of DNA that direct syntheses of specific proteins associated with traits in organisms. These consist of various combinations of four different nucleotides that encode this information through their sequences. 2. Known patterns of inheritance can be used to make predictions about genetic var ...
Genetic engineering
Genetic engineering, also called genetic modification, is the direct manipulation of an organism's genome using biotechnology. It is therefore a set of technologies used to change the genetic makeup of cells, including the transfer of genes within and across species boundaries to produce improved or novel organisms. New DNA may be inserted in the host genome by first isolating and copying the genetic material of interest using molecular cloning methods to generate a DNA sequence, or by synthesizing the DNA, and then inserting this construct into the host organism. Genes may be removed, or ""knocked out"", using a nuclease. Gene targeting is a different technique that uses homologous recombination to change an endogenous gene, and can be used to delete a gene, remove exons, add a gene, or introduce point mutations.An organism that is generated through genetic engineering is considered to be a genetically modified organism (GMO). The first GMOs were bacteria generated in 1973 and GM mice in 1974. Insulin-producing bacteria were commercialized in 1982 and genetically modified food has been sold since 1994. Glofish, the first GMO designed as a pet, was first sold in the United States December in 2003.Genetic engineering techniques have been applied in numerous fields including research, agriculture, industrial biotechnology, and medicine. Enzymes used in laundry detergent and medicines such as insulin and human growth hormone are now manufactured in GM cells, experimental GM cell lines and GM animals such as mice or zebrafish are being used for research purposes, and genetically modified crops have been commercialized.