Genomic imprinting and human disease
... Mammalian genomic imprinting is an epigenetic marking phenomenon leading to mono-allelic expression of a subset of genes [1]. Mono-allelic expression depends entirely on the parental origin of the gene. Thus some imprinted genes are expressed only from the maternally inherited allele, whereas others ...
... Mammalian genomic imprinting is an epigenetic marking phenomenon leading to mono-allelic expression of a subset of genes [1]. Mono-allelic expression depends entirely on the parental origin of the gene. Thus some imprinted genes are expressed only from the maternally inherited allele, whereas others ...
Evolution of cis-regulatory elements in duplicated genes of yeast
... suggest that the evolution of functional novelty has a substantial role in yeast duplicate gene evolution. Gene expression changes are recognized to be of great importance in the functional divergence of duplicate genes [1,2]. Using microarray data, a recent study revealed an unexpectedly high rate ...
... suggest that the evolution of functional novelty has a substantial role in yeast duplicate gene evolution. Gene expression changes are recognized to be of great importance in the functional divergence of duplicate genes [1,2]. Using microarray data, a recent study revealed an unexpectedly high rate ...
Analyzing ATP Synthase Gene Activity in Elizabethkingia anophelis
... The ATP synthase delta chain significantly increased under the presence of the Imipenem antibiotic (Table 1). The function of this subunit is to attach the alpha and beta subunits to the peripheral stalk and is crucial to prevent these subunits from rotating5. Thus if gene expression is increased it ...
... The ATP synthase delta chain significantly increased under the presence of the Imipenem antibiotic (Table 1). The function of this subunit is to attach the alpha and beta subunits to the peripheral stalk and is crucial to prevent these subunits from rotating5. Thus if gene expression is increased it ...
EXTENDED CONCEPT OF KNOWLEDGE FOR EVOLUTIONARY
... skepticism — do we have any real knowledge at all? If we do not limit ourselves by the traditional concept of knowledge as belief (or proposition), we can give a certain answer, yes we do! There are many things that we certainly can do (if we just want to) — in many respects we are capable of doing ...
... skepticism — do we have any real knowledge at all? If we do not limit ourselves by the traditional concept of knowledge as belief (or proposition), we can give a certain answer, yes we do! There are many things that we certainly can do (if we just want to) — in many respects we are capable of doing ...
The enduracidin biosynthetic gene cluster from
... with a condensation domain (C domain) similar to those found in other lipopeptide systems for the coupling of an acyl group to the starting amino acid. The sixth module of EndB, corresponding to Thr8, is missing an adenylation domain (A domain) and this module is presumed to be loaded in trans by th ...
... with a condensation domain (C domain) similar to those found in other lipopeptide systems for the coupling of an acyl group to the starting amino acid. The sixth module of EndB, corresponding to Thr8, is missing an adenylation domain (A domain) and this module is presumed to be loaded in trans by th ...
Brevifollis gellanilyticus gen. nov., sp. nov., a gellan-gum
... et al. (1994). Cell morphology was observed by micrographs (Fig. 1) taken by JEOL Datum (Tokyo, Japan) using transmission electron microscopy with negative staining using the model 1010 at an acceleration voltage of 100Kv, with cells grown for 3 days or 1 week at 30 uC, namely at their middle and la ...
... et al. (1994). Cell morphology was observed by micrographs (Fig. 1) taken by JEOL Datum (Tokyo, Japan) using transmission electron microscopy with negative staining using the model 1010 at an acceleration voltage of 100Kv, with cells grown for 3 days or 1 week at 30 uC, namely at their middle and la ...
TaWRKY70 transcription factor in wheat QTL-2DL regulates
... Fusarium head blight (FHB) is one of the major constraints in wheat and barley production. Several methods have been used to manage FHB in wheat, among which the use of FHB resistant cultivars is considered to be the most efficient, economic and environmental friendly method1. More than 200 QTL hav ...
... Fusarium head blight (FHB) is one of the major constraints in wheat and barley production. Several methods have been used to manage FHB in wheat, among which the use of FHB resistant cultivars is considered to be the most efficient, economic and environmental friendly method1. More than 200 QTL hav ...
Promoter identification and analysis of key glycosphingolipid
... transcription initiation region had five alternative splicing sites and two promoters, but other genes in the glycosphingolipid biosynthesis-globo series pathway were not studied (Gan et al., 2016). Moreover, other regions of the two promoters can affect gene expression; thus, further studies are re ...
... transcription initiation region had five alternative splicing sites and two promoters, but other genes in the glycosphingolipid biosynthesis-globo series pathway were not studied (Gan et al., 2016). Moreover, other regions of the two promoters can affect gene expression; thus, further studies are re ...
Cloning in bacteria other than Escherichia coli
... with specialist properties, e.g. regulatable high-level gene expression. However, use of E. coli is not always practicable because it lacks some auxiliary biochemical pathways that are essential for the phenotypic expression of certain functions, e.g. degradation of aromatic compounds, antibiotic sy ...
... with specialist properties, e.g. regulatable high-level gene expression. However, use of E. coli is not always practicable because it lacks some auxiliary biochemical pathways that are essential for the phenotypic expression of certain functions, e.g. degradation of aromatic compounds, antibiotic sy ...
Why does the giraffe have such a long neck? Analysis zeroes in on
... Two scientists, Douglas Cavener and Morris Agaba, conducted the study. Cavener and Agaba compared genomes of giraffes, okapi, and 40 other animals including humans. The scientists wanted to figure out what genes might give giraffes their qualities. The okapi and giraffe genomes are very similar. Ther ...
... Two scientists, Douglas Cavener and Morris Agaba, conducted the study. Cavener and Agaba compared genomes of giraffes, okapi, and 40 other animals including humans. The scientists wanted to figure out what genes might give giraffes their qualities. The okapi and giraffe genomes are very similar. Ther ...
Reproduction
... Reproduction is the process by which living things produce new individuals of the same type. ...
... Reproduction is the process by which living things produce new individuals of the same type. ...
4 - marric.us
... Instruction: Answer each question you may use notes, text book, etc. This will help you prepare you for the unit test, but may be used on the unit test. 1. Why do offspring look like their parents? ...
... Instruction: Answer each question you may use notes, text book, etc. This will help you prepare you for the unit test, but may be used on the unit test. 1. Why do offspring look like their parents? ...
Bioinformatic Resources, Challenges, and
... sets currently include all Arabidopsis proteins, all Arabidopsis DNA sequences, bacterial artificial chromosome end and expressed sequence tag sequences only, and others. In the future, more specific data sets such as genes, markers, transcripts, as well as nonplant sequences, will be available. The ...
... sets currently include all Arabidopsis proteins, all Arabidopsis DNA sequences, bacterial artificial chromosome end and expressed sequence tag sequences only, and others. In the future, more specific data sets such as genes, markers, transcripts, as well as nonplant sequences, will be available. The ...
The Development of a Genetic Marker for Resistance to Fescue
... (Epicentre, Cambridge, UK). A genomic amplification was then performed for the isolated DNA samples using the GenomiPhi DNA amplification kit (GE Healthcare, Piscataway, NJ). The GenomiPhi kit uses the bacteriophage Phi29 DNA polymerase to exponentially amplify linear DNA templates using a strand di ...
... (Epicentre, Cambridge, UK). A genomic amplification was then performed for the isolated DNA samples using the GenomiPhi DNA amplification kit (GE Healthcare, Piscataway, NJ). The GenomiPhi kit uses the bacteriophage Phi29 DNA polymerase to exponentially amplify linear DNA templates using a strand di ...
Meeting of the International Society for Genetic Eye Diseases
... Dr. Weleber is a Clinician‐Scientist in the field of Ocular Genetics, retinal degenerations, visual electrophysiology, visual field methodology, and design and conduct of clinical trials. He founded the first visual electrophysiology service at OHSU in 1974 and was Director of the Visual Functio ...
... Dr. Weleber is a Clinician‐Scientist in the field of Ocular Genetics, retinal degenerations, visual electrophysiology, visual field methodology, and design and conduct of clinical trials. He founded the first visual electrophysiology service at OHSU in 1974 and was Director of the Visual Functio ...
Molecular Genetics
... understanding of the structure of graphite and other carbon compounds even before her appointment to King's College. Unfortunately, her reputation did not precede her. James Watson's unflattering portrayal of Franklin in his account of the discovery of DNA's structure, entitled "The Double Helix," d ...
... understanding of the structure of graphite and other carbon compounds even before her appointment to King's College. Unfortunately, her reputation did not precede her. James Watson's unflattering portrayal of Franklin in his account of the discovery of DNA's structure, entitled "The Double Helix," d ...
The Maintenance and Propagation of Plasmid Genes in Bacterial
... two obvious possibilities present themselves. Either the plasmid could co-segregate with the chromosome (for example, as part of the nucleoid), or it could actively segregate independently via a membrane attachment site. Multicopy plasmids, in principle, can use an alternative strategy since their c ...
... two obvious possibilities present themselves. Either the plasmid could co-segregate with the chromosome (for example, as part of the nucleoid), or it could actively segregate independently via a membrane attachment site. Multicopy plasmids, in principle, can use an alternative strategy since their c ...
PowerPoint - Isaac Newton Institute
... Even if theoretical null N(0,1) is correct for an individual zj of a null gene, the zj’s for the null genes may not behave as N(0,1) variates in the ensemble of z1,…,zN. If they don’t, then the Benjamini-Hochberg procedure will break down using P-values based on theoretical null. ...
... Even if theoretical null N(0,1) is correct for an individual zj of a null gene, the zj’s for the null genes may not behave as N(0,1) variates in the ensemble of z1,…,zN. If they don’t, then the Benjamini-Hochberg procedure will break down using P-values based on theoretical null. ...
A Novel Algorithm of Gene Expression Programming Based on
... the GEP of China in some period. The second column（K）in table 1 and table 2 describes the sum of net value of fixed assets and the average balance of floating assets in the corresponding year. The third column（L）describes the number of employed person, including all kind of workers and peasants. The ...
... the GEP of China in some period. The second column（K）in table 1 and table 2 describes the sum of net value of fixed assets and the average balance of floating assets in the corresponding year. The third column（L）describes the number of employed person, including all kind of workers and peasants. The ...
Fact Sheet 61|TUBEROUS SCLEROSIS COMPLEX In summary
... For couples where the familial mutation is identified, testing may be available during a pregnancy to determine whether or not the baby has inherited the mutation. It may also be possible to undergo pre-implantation genetic diagnosis (PGD) on an embryo created using in vitro fertilisation (IVF) to e ...
... For couples where the familial mutation is identified, testing may be available during a pregnancy to determine whether or not the baby has inherited the mutation. It may also be possible to undergo pre-implantation genetic diagnosis (PGD) on an embryo created using in vitro fertilisation (IVF) to e ...
Topic 1: Statistical analysis (2 hours)
... totipotent; stem cells are derived from blastocysts / human embryos, left over from IVF / placenta / umbilical cord / some adult tissues; new techniques / technologies rely on replacing diseased / dysfunctional cells with healthy / functioning ones; need to identify desired type of stem cell and gro ...
... totipotent; stem cells are derived from blastocysts / human embryos, left over from IVF / placenta / umbilical cord / some adult tissues; new techniques / technologies rely on replacing diseased / dysfunctional cells with healthy / functioning ones; need to identify desired type of stem cell and gro ...
CHAPTER 8
... due to the accumulation of mutations over many generations. The members of a gene family usually encode proteins with similar but specialized functions. The specialization may occur in different cells or at different stages of development. C5. Answer: You would expect α1 and α2 to be more similar, b ...
... due to the accumulation of mutations over many generations. The members of a gene family usually encode proteins with similar but specialized functions. The specialization may occur in different cells or at different stages of development. C5. Answer: You would expect α1 and α2 to be more similar, b ...
Natural selection and the function of genome imprinting:
... Imprinting and ‘other’ parental origin effects: do they have anything in common? The observation that parental origin effects occur in a wide variety of organisms (Table 1) cannot be used as an argument that parental origin effects, per se, have been selected to serve some purpose because the genera ...
... Imprinting and ‘other’ parental origin effects: do they have anything in common? The observation that parental origin effects occur in a wide variety of organisms (Table 1) cannot be used as an argument that parental origin effects, per se, have been selected to serve some purpose because the genera ...
Globin gene family
... from each other between 2 and 4 billion years ago • Highly conserved genes can be studied in one model organism, and the results applied to other organisms Copyright © 2008 Pearson Education Inc., publishing as Pearson Benjamin Cummings ...
... from each other between 2 and 4 billion years ago • Highly conserved genes can be studied in one model organism, and the results applied to other organisms Copyright © 2008 Pearson Education Inc., publishing as Pearson Benjamin Cummings ...
Allele- and parent-of-origin-specific effects on expression of the
... OTAGO database, which contains data on imprinted genes and their related effects (http://igc. otago.ac.nz/). Currently in this database, only 34 bovine genes have been found to be imprinted or non-imprinted whereas 332 and 228 entries exist for human and mouse, respectively. Since 2011, the number o ...
... OTAGO database, which contains data on imprinted genes and their related effects (http://igc. otago.ac.nz/). Currently in this database, only 34 bovine genes have been found to be imprinted or non-imprinted whereas 332 and 228 entries exist for human and mouse, respectively. Since 2011, the number o ...
Genetic engineering
Genetic engineering, also called genetic modification, is the direct manipulation of an organism's genome using biotechnology. It is therefore a set of technologies used to change the genetic makeup of cells, including the transfer of genes within and across species boundaries to produce improved or novel organisms. New DNA may be inserted in the host genome by first isolating and copying the genetic material of interest using molecular cloning methods to generate a DNA sequence, or by synthesizing the DNA, and then inserting this construct into the host organism. Genes may be removed, or ""knocked out"", using a nuclease. Gene targeting is a different technique that uses homologous recombination to change an endogenous gene, and can be used to delete a gene, remove exons, add a gene, or introduce point mutations.An organism that is generated through genetic engineering is considered to be a genetically modified organism (GMO). The first GMOs were bacteria generated in 1973 and GM mice in 1974. Insulin-producing bacteria were commercialized in 1982 and genetically modified food has been sold since 1994. Glofish, the first GMO designed as a pet, was first sold in the United States December in 2003.Genetic engineering techniques have been applied in numerous fields including research, agriculture, industrial biotechnology, and medicine. Enzymes used in laundry detergent and medicines such as insulin and human growth hormone are now manufactured in GM cells, experimental GM cell lines and GM animals such as mice or zebrafish are being used for research purposes, and genetically modified crops have been commercialized.