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Neural/Genetic/hormonal mechanisms in
Neural/Genetic/hormonal mechanisms in

... Genetics (breed) plays only a part in the temperament of an individual dog and scientific studies from around the world show that environment probably has a far greater effect. A large percentage of dog biting incidents are due to the irresponsible actions of owners, who have either not taken the ti ...
Heredity - questions
Heredity - questions

... (f) If Jane had been normal, what are the possible genotypes of the grandparents? (g) Is it possible that the allele for PKU is sex-linked? 13 One form of colour-blindness is a sex-linked inherited condition controlled by a recessive allele. Use the symbols X and Y for the sex chromosomes and N and ...
Chapter 15
Chapter 15

... • Offspring with a phenotype matching one of the parental phenotypes are called parental types • Offspring with nonparental phenotypes (new combinations of traits) are called recombinant types, or recombinants • A 50% frequency of recombination is observed ...
A Dihybrid Cross - HCC Learning Web
A Dihybrid Cross - HCC Learning Web

... Mendel used the scientific approach to identify two laws of inheritance • Mendel discovered the basic principles of heredity by breeding garden peas in carefully planned experiments. • Advantages of pea plants for genetic study: – There are many varieties with distinct heritable features, or charac ...
"Tooth Agenesis". - Thimios Mitsiadis
"Tooth Agenesis". - Thimios Mitsiadis

... cases of tooth agenesis can help to elucidate mechanisms involved in human odontogenesis, when phenotypes are carefully evaluated and correlated with associated genotypes. Phenotypes can be restricted to the dentition or include also defects in other tissues or organs, most frequently clefts of the ...
[Full text/PDF]
[Full text/PDF]

... Conditional analysis methods have been developed to directly obtain the conditional variation of a complex trait by excluding the contribution of a component trait. These methods estimate the extra effects and variance components associated with the complex phenotypic trait that are independent of a ...
Investigating sea turtle migration using DNA markers
Investigating sea turtle migration using DNA markers

... of mtDNA control region sequences in sea turtles, and has been applied in direct sequencing assays(and denaturing gradient gel electrophoresis) to studies of green turtle population structure in the Indo-Pacific region [lo’]. Population-specific mtDNA markers (unique variants or frequency profiles o ...
PDF-729K - ScienceCentral
PDF-729K - ScienceCentral

... and cellular deficits in this disorder. For example, twin studies revealed that concordance rate in monozygotic twins (63%) was higher than that in the dizygotic twins (9%) [9]. Half of the stutterers had a family history, and risk to first degree relative was 15%. Several large families with multip ...
Mendel Powerpoint
Mendel Powerpoint

... Chapter 11 Introduction to Genetics ...
Genetic diversity and connectivity shape herbivore load within an
Genetic diversity and connectivity shape herbivore load within an

... Abstract. Host genetic diversity and genotypic identity have been reported to affect the abundance, species richness and species diversity of associated herbivore communities. Recent work, however, suggests that these effects are highly context-dependent and that the magnitude and direction of the e ...
Genetic Causes of Phenotypic Adaptation to the Second
Genetic Causes of Phenotypic Adaptation to the Second

... DNA libraries were then pooled and sequenced with a MiSeq apparatus using the standard kit v2 (Illumina, California, USA) generating paired end reads of 2x250bp in the Bordeaux University’s genomic facility. All sequencing data (filtering and mapping) was performed using the available tools at the p ...
Alfred Henry Sturtevant - National Academy of Sciences
Alfred Henry Sturtevant - National Academy of Sciences

... age map. He and others had noticed, however, that excessive variation in the amount of crossing-over sometimes occurs. The factors responsible were isolated by Sturtevant and by Muller around 1915 and were shown to act as dominant cross-over suppressors. The first clue to the nature of these factors ...
Genetics of behavioural isolation
Genetics of behavioural isolation

... morphological changes. In the absence of such traits, indirect genetic methods have been widely used which score for the acceptance of mates with various backcrossed genotypes which are then transformed into classical quantitative trait loci (QTLs) studies which indicate the chromosomal regions resp ...
14_DetailLectOut_jkAR
14_DetailLectOut_jkAR

...  A diploid organism inherits one set of chromosomes from each parent.  Each diploid organism has a pair of homologous chromosomes and, therefore, two copies of each gene.  These homologous loci may be identical, as in the true-breeding plants of the P generation.  Alternatively, the two alleles ...
The Population Genetic Theory of Hidden Variation and
The Population Genetic Theory of Hidden Variation and

... of phenotypes underlie all Darwinian evolution, the finding that variability itself depends on the genotype and can evolve could have important implications for tempo and mode of the evolutionary process. In particular, if variability is itself adaptive, evolution actively forms and influences its o ...
DNA Duplication Associated with Charcot-Marie-Tooth Disease Type 1A. Lupski, et al., 1991 Cell, Vol. 66, 219-232, July 26, 1991,
DNA Duplication Associated with Charcot-Marie-Tooth Disease Type 1A. Lupski, et al., 1991 Cell, Vol. 66, 219-232, July 26, 1991,

... locus, by dosage differences at RFLP alleles, and by two-color fluorescence in situ hybridization. Pulsed-field gel electrophoresis of genomic DNA from patients of different ethnic origins showed a novel Sacll fragment of 500 kb associated with CMTlA. A severely affected CMTIA offspring from a matin ...
Complex genetic patterns in human arise from a simple
Complex genetic patterns in human arise from a simple

... geographically uneven sampling scheme used in most, if not all, worldwide studies on human genetics may have generated these clusters, which would merely reflect sampling bias. Rosenberg et al. [3] challenged this view taking advantage of an expanded dataset to argue that, among all other variables ...
meiosis and heredity
meiosis and heredity

... c. genes contained in the gametes that fuse to form a zygote d. recombination between sister chromatids e. physical arrangement of chromosomes along the metaphase plate in preparation for anaphase 9. Which of the following is not one of Mendel's three hypothesis to explain the results of his P, F1 a ...
Town Hall on Genetic Engineering
Town Hall on Genetic Engineering

... “designer babies”. That means they are able to pick and choose which genes they want their children to have: intelligence, athleticism and good looks. There are many pros and cons to this technology. New Orleans is putting genetic engineering up to a vote: should people be allowed to use genetic eng ...
E46
E46

... of upland cotton (Gossypium hirsutum L.). The gossypol content and the number of glands in the seed and plant are largely controlled by alleles at those loci, while genes at other minor loci can modify the phenotypes (Lee 1962; Calhoun 1997). A desired genotype with a high gossypol plant and a low g ...
Exome sequencing as a tool for Mendelian disease gene discovery
Exome sequencing as a tool for Mendelian disease gene discovery

... traits typically requires resequencing instead of genotyping83 and has therefore been challenging. Such studies have largely been limited to assessing rare variants that have been found by the targeted sequencing of candidate genes or of genomic regions identified by linkage or genome-wide associati ...
LIMIX: genetic analysis of multiple traits
LIMIX: genetic analysis of multiple traits

... have been proposed, first in the field of animal breeding [10] and, more recently, also in the context of GWAS [11, 12]. In genetics, the use of general-purpose mixed modeling tools is rare (e.g. ref. [13]), mainly because these lack the computational efficiency that is required to handle larger sam ...
chromosome disorders.
chromosome disorders.

... • Trisomy can exist for any part of the genome, but trisomy for a whole chromosome is rarely compatible with life. • Monosomy for an entire chromosome is almost always lethal; an important exception is monosomy for the X chromosome, as seen in Turner syndrome. ...
Deleterious mutations can reduce differentiation in small, subdivided
Deleterious mutations can reduce differentiation in small, subdivided

... N = 100. The same holds for a subdivided population. The total heterozygosity in a subdivided population with N m = 1 is a little higher but very close to the value in one large population. Restricted migration (Nm = 0.1) reduces the heterozygosity within subpopulations but increases the total heter ...
– findings from cross-species Anxiety genetics genome-wide approaches
– findings from cross-species Anxiety genetics genome-wide approaches

... Anxiety disorders are complex diseases, which often occur in combination with major depression, alcohol use disorder, or general medical conditions. Anxiety disorders were the most common mental disorders within the EU states in 2010 with 14% prevalence. Anxiety disorders are triggered by environmen ...
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Medical genetics

Medical genetics is the specialty of medicine that involves the diagnosis and management of hereditary disorders. Medical genetics differs from human genetics in that human genetics is a field of scientific research that may or may not apply to medicine, but medical genetics refers to the application of genetics to medical care. For example, research on the causes and inheritance of genetic disorders would be considered within both human genetics and medical genetics, while the diagnosis, management, and counseling of individuals with genetic disorders would be considered part of medical genetics.In contrast, the study of typically non-medical phenotypes such as the genetics of eye color would be considered part of human genetics, but not necessarily relevant to medical genetics (except in situations such as albinism). Genetic medicine is a newer term for medical genetics and incorporates areas such as gene therapy, personalized medicine, and the rapidly emerging new medical specialty, predictive medicine.
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