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Genetic recombination in plants
Genetic recombination in plants

... An important cautionary note, however, is that, because most fine-scale studies of recombination have assayed recombination rates only within genes, it is not possible to conclude that all hot spots are genes. One way to settle this question would be to identify a collection of recombination hot spo ...
Synthetic Biology and the CBD
Synthetic Biology and the CBD

... Predicted to be almost a 40 billion dollar (US) market by 2020, industrial activity in synthetic biology is rapidly exploding as new genome editing tools and cheaper synthesis of DNA make it easier and faster to genetically re-design or alter biological organisms. Synthetic biology-derived products ...
2015.04.09.UMinn Resurgence of Ref Quality Genomes
2015.04.09.UMinn Resurgence of Ref Quality Genomes

... •  Less than 1% of exonic bases missing •  Genome-specific genes enriched for disease resistance •  Reflects their geographic and environmental diversity •  Assemblies fragmented at (high copy) repeats •  Difficult to identify full length gene models and regulatory features ...
The Genetics of SMA - Families of SMA Canada
The Genetics of SMA - Families of SMA Canada

... the promoter, then too much or too little RNA will be made. • If a single nucleotide in the DNA is changed, then a different amino acid will be incorporated into the protein. This could alter the folding and the function of the protein itself. These types of single nucleotide changes are called poin ...
A newly discovered human -globin gene
A newly discovered human -globin gene

... To compare the mRNA profiles in the reticulocytes circulating at the time of birth with those in adults, high-throughput arrays were generated from the blood of 28 separate donors (14 cord blood, 14 adult blood). Platelets were removed from the samples by lowspeed centrifugation, and nucleated cells ...
5.1.2 Meiosis and Variation
5.1.2 Meiosis and Variation

... in seahorses is known as disruptive selection. This is where the extreme phenotypes are more likely to survive and reproduce than the intermediate phenotypes. (b) ...
aeiab Meiosis
aeiab Meiosis

... frequency of crossing over, and for demonstrating the random assortment of the chromosomes to the daughter nuclei during meiosis I. In certain fungi such as the pink bread mold, Neurospora crassa, and Sordaria fimicola (the organism you will study during this lab), meiosis occurs within a structure ...
Driscoll Katee Driscoll Dr. Ely Genetics October 20, 2013 Effects of
Driscoll Katee Driscoll Dr. Ely Genetics October 20, 2013 Effects of

... lowest error rates were used to generate the predicted length of the HTT genes. In other words, instead of using multiple probes and averaging the predicted lengths for each set, the single most accurate set of predicted length was used to represent the length. This model predicted CAG repeat length ...
Molecular pathogenesis of feline leukemia virus
Molecular pathogenesis of feline leukemia virus

... efficiently amplified but long enough to efficiently circularize. Although dilution of the template before ligation to circularize is required for the inverse PCR, it can also result in inefficient amplification. Another strategy, linker-mediated PCRs, can avoid the use of diluted and circularized t ...
Module one assignment
Module one assignment

... since I was a child. At age 11 I got my first bay cob called Ches, a quiet horse who taught me to ride. Later came a chestnut Anglo-Arab called Little John. He was anything but quiet, but taught me a great deal about horse behaviour and training. Without any real help I somehow turned him from a rea ...
ppt - Chair of Computational Biology
ppt - Chair of Computational Biology

... For each of three human (a–c) and mouse (d–f) chromosomes, the positions of orthologous landmarks are plotted along the x axis and the corresponding position of the landmark on chromosomes in the other genome is plotted on the y axis. Different chromosomes in the corresponding genome are differentia ...
Commentary: Lamarckian inheritance and
Commentary: Lamarckian inheritance and

... more nor less important than crossing-over of chromosomes, transcription factors, transposable elements or the variety of non-coding RNA species and other regulatory molecules that occur. Long non-coding RNAs can silence genes. The whole of the X chromosome in the female zygote is silenced by an X-i ...
Homologous pigmentation mutations in human, mouse and other
Homologous pigmentation mutations in human, mouse and other

... Mouse coat colour genes were among the first mammalian mutant genes known. For most of this century they have been studied as a model of the way genes interact to regulate the developmental and cellular function of the pigment cell or melanocyte. There are about 80 classical mutations that have an e ...
Imprinted SNRPN within chromosome territories
Imprinted SNRPN within chromosome territories

... Human myeloid leukemia HL60 cells were cultured in RPMI1640 containing 10% FBS at 37°C in an atmosphere of 5% CO2. The HL60 cells were fractionated by centrifugal elutriation. Cultured cells (3×108 cells) were loaded onto a Beckman elutriator rotor at 2,000 rpm at 4°C with flow of 0.3% gelatin in PB ...
homolog of the agouti gene
homolog of the agouti gene

... respectively. The glyceraldehyde-3-phosphate dehydrogenase (GAPDH) primers (Clontech) were added to separate PCR reactions as a control for thS same reverse transcriptase product. Amplified PCR products were subjected to electrophoresis on 1% agarose gel. ...
A Serine/Proline-Rich Protein Is Fused To HRX in t(4
A Serine/Proline-Rich Protein Is Fused To HRX in t(4

... cDNA library was constructed from mRNA isolated from t(4;11)-carrying leukemia cells (ALL no. 1, Fig 1A). The library was screened with an HRX cDNA probe that spanned the potential fusion site (probe B6). Four types of clones were obtained (Fig 2B) representing either wild-type HRX cDNAs or three di ...
Chapter 10: Sexual Reproduction and Genetics
Chapter 10: Sexual Reproduction and Genetics

... Each student in your biology class has characteristics passed on to them by their parents. Each characteristic, such as hair color, height, or eye color, is called a trait. The instructions for each trait are located on chromosomes, which are found in the nucleus of cells. The DNA on chromosomes is ...
Microarray Data Analysis for Detection and Classification of Viral
Microarray Data Analysis for Detection and Classification of Viral

... proved in detection of pathogenic viruses [10]. Of other applications of microarray are identification of different bioterrorist threat agents [11] and examining the quality of water and food for the detection of pathogens [12]. However, microarray data analysis in infectious diseases is not easy, b ...
The Nature of Nurture and the Future of Evodevo: Toward a Theory
The Nature of Nurture and the Future of Evodevo: Toward a Theory

... of methylation are heritable across cell divisions, can persist across generations, and may be altered in response to a range of environmental factors (reviewed ...
Living Things
Living Things

... Mutations Mutations can cause a cell to produce an incorrect protein during protein synthesis. As a result, the organism’s trait, or phenotype, may be different from what it normally would have been. ...
Mendel Loved His Peas! - McCarthy`s Cool Science
Mendel Loved His Peas! - McCarthy`s Cool Science

... b. Mating can be easily controlled. (Self-pollinating or cross-pollinating) c. They are small, grow easily, mature quickly and produce many offspring=QUICK RESULTS! d. Don’t talk back to scientists. ...
Evolutionary divergence and functions of the ADAM and ADAMTS
Evolutionary divergence and functions of the ADAM and ADAMTS

... ADAM subfamily B This group contains four genes: ADAM2, ADAM18, ADAM32 and ADAM9 (Figure 2, top). The first three of these genes in this subfamily lack peptidase activity and are associated with sperm development and fertilisation. Adam2 in mice is involved in spermatogenesis and fertility, but the ...
Oral squamous cell carcinoma (OSCC) – molecular, viral and
Oral squamous cell carcinoma (OSCC) – molecular, viral and

... a strong association between the presence of HPV DNA – specifically HPV16 and OSCC. This meta-analysis showed that HPV significantly increases the risk for OSCC, compared with controls (OR 3.98; 95% CI: 2.62–6.02). HPVs specifically target the undifferentiated proliferative basal cells of epithelial ...
Virginia State Science Olympiad Regional Tournament
Virginia State Science Olympiad Regional Tournament

... Virginia State Science Olympiad Regional Tournament 2013 – Division B Heredity ...
Identify differential APA usage from RNA-seq
Identify differential APA usage from RNA-seq

... The gtf file should have an attribute (metadata column for the GRanges object) called “gene id” that ends with “ PRE” or “ POST” to address respectively the short and the long isoforms. An element in the annotation is considered “PRE” (i.e. common to the short and long isoform of the transcript) if ...
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History of genetic engineering

Genetic modification caused by human activity has been occurring since around 12,000 BC, when humans first began to domesticate organisms. Genetic engineering as the direct transfer of DNA from one organism to another was first accomplished by Herbert Boyer and Stanley Cohen in 1973. Advances have allowed scientists to manipulate and add genes to a variety of different organism and induce a range of different effects. Since 1976 the technology has been commercialised, with companies producing and selling genetically modified food and medicine.
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