1200 Paul Winter
... of a family from the Aland islands The index case was a 5-year old girl who he documented as having a series of lifethreatening bleeding episodes. At the age of 14 years, she subsequently bled to ...
... of a family from the Aland islands The index case was a 5-year old girl who he documented as having a series of lifethreatening bleeding episodes. At the age of 14 years, she subsequently bled to ...
Adaptive Speciation: Introduction
... “Adaptive speciation” refers to speciation processes in which the splitting is an adaptive response to disruptive selection caused by frequency-dependent biological interactions. Naturally, the question of how often and under which circumstances frequency-dependent interactions are likely to induce ...
... “Adaptive speciation” refers to speciation processes in which the splitting is an adaptive response to disruptive selection caused by frequency-dependent biological interactions. Naturally, the question of how often and under which circumstances frequency-dependent interactions are likely to induce ...
variations in variation and selection: the ubiquity
... transition probability might be. (The existence of other absorbing conditions, or absorbing regions of the state space, may render the transition probability into a particular absorbing state zero if the system enters one of those other absorbing regions of the space.) Crystal stability. Once a crys ...
... transition probability might be. (The existence of other absorbing conditions, or absorbing regions of the state space, may render the transition probability into a particular absorbing state zero if the system enters one of those other absorbing regions of the space.) Crystal stability. Once a crys ...
Genetic Inversion: Relationships Among Species
... for black fur then it causes the animal to have white fur thus blending better with its environment. Disadvantageous – same as above but either the environment was different so the color change was not preferred or the inactivated gene coded for a protein that is essential for the survival of the or ...
... for black fur then it causes the animal to have white fur thus blending better with its environment. Disadvantageous – same as above but either the environment was different so the color change was not preferred or the inactivated gene coded for a protein that is essential for the survival of the or ...
Progress in the Understanding of the Genetic Etiology of Vertebral
... Congenital vertebral malformations (CVM) in humans represent a significant health problem because they may cause kyphosis and/or scoliosis, resulting in back and neck pain, disability, cosmetic disfigurement, and functional distress. The true incidence of vertebral malformations is unknown, although ...
... Congenital vertebral malformations (CVM) in humans represent a significant health problem because they may cause kyphosis and/or scoliosis, resulting in back and neck pain, disability, cosmetic disfigurement, and functional distress. The true incidence of vertebral malformations is unknown, although ...
video slide
... Concept 14.3: Inheritance patterns are often more complex than predicted by simple Mendelian genetics • The relationship between genotype and phenotype is rarely as simple as in the pea plant characters Mendel studied • Many heritable characters are not determined by only one gene with two alleles ...
... Concept 14.3: Inheritance patterns are often more complex than predicted by simple Mendelian genetics • The relationship between genotype and phenotype is rarely as simple as in the pea plant characters Mendel studied • Many heritable characters are not determined by only one gene with two alleles ...
Table 2
... pathways, can help prioritize candidate genes for further analysis. However, with rare exceptions, mutations in genes ...
... pathways, can help prioritize candidate genes for further analysis. However, with rare exceptions, mutations in genes ...
Probability in Biology: The Case of Fitness Roberta L. Millstein
... premise that I use the term Struggle for Existence in a large and metaphorical sense, including dependence of one being on another, and including (which is more important) not only the life of the individual, but success in leaving progeny” (1859: 62; emphasis added) and “can we doubt (remembering t ...
... premise that I use the term Struggle for Existence in a large and metaphorical sense, including dependence of one being on another, and including (which is more important) not only the life of the individual, but success in leaving progeny” (1859: 62; emphasis added) and “can we doubt (remembering t ...
A quantitative genetic competition model for
... assortative mating based on this character, frequency- and density-dependent competition can subdivide a population with an initially unimodal character distribution. The character distribution becomes bimodal, and the subpopulations corresponding to the two modes are reproductively separated becaus ...
... assortative mating based on this character, frequency- and density-dependent competition can subdivide a population with an initially unimodal character distribution. The character distribution becomes bimodal, and the subpopulations corresponding to the two modes are reproductively separated becaus ...
Sporadic Hypertrophic Cardiomyopathy Due to De Novo Myosin
... restriction enzyme digestion. Paternity was confirmed by demonstration of inheritance of appropriate alleles at eight polymorphic dimeric short tandem repeat sequences (STRs): APOAII, APOCII, ASS, DIS103, DlSl 16, GCG, INT2, and PLA2 (23-29), using PCR conditions as described previously with end-lab ...
... restriction enzyme digestion. Paternity was confirmed by demonstration of inheritance of appropriate alleles at eight polymorphic dimeric short tandem repeat sequences (STRs): APOAII, APOCII, ASS, DIS103, DlSl 16, GCG, INT2, and PLA2 (23-29), using PCR conditions as described previously with end-lab ...
The Perceived Personal Control (PPC) questionnaire: reliability and
... (3.1%). Parallel analysis suggested a two-factor solution. However, the second factor was weak (accounting for only 13.9% of the variance) and following oblique rotation had an eigenvalue of .70, suggesting the factor had less explanatory value than any individual scale item. The weakness of the fac ...
... (3.1%). Parallel analysis suggested a two-factor solution. However, the second factor was weak (accounting for only 13.9% of the variance) and following oblique rotation had an eigenvalue of .70, suggesting the factor had less explanatory value than any individual scale item. The weakness of the fac ...
Parental Age Affects Somatic Mutation Rates in
... different age (Fig. 1, A, B, and E). In contrast, the adaxial epidermal cell number decreased with parental age (Fig. 1F). The progeny of 53-DAS parents had a considerably lower cell number compared with those of 38-DAS selffertilized parents (P , 0.001; Fig. 1F). Reciprocal crosses 38 3 48, 48 3 38 ...
... different age (Fig. 1, A, B, and E). In contrast, the adaxial epidermal cell number decreased with parental age (Fig. 1F). The progeny of 53-DAS parents had a considerably lower cell number compared with those of 38-DAS selffertilized parents (P , 0.001; Fig. 1F). Reciprocal crosses 38 3 48, 48 3 38 ...
Commentary: A century of Mendelism: on Johannsen`s genotype
... genotype’. Johannsen soon realized that Darwinian thinking had put the emphasis on the transmission of properties from ancestors to their descendents rather than on the mechanics behind the transmission of these properties. Such a ‘transmission conception’ of heredity appears to be inevitable for, s ...
... genotype’. Johannsen soon realized that Darwinian thinking had put the emphasis on the transmission of properties from ancestors to their descendents rather than on the mechanics behind the transmission of these properties. Such a ‘transmission conception’ of heredity appears to be inevitable for, s ...
IGA 8/e Chapter 2
... set contains approximately 4 m of DNA. The average size of each chromosome during metaphase of mitosis is 13 m. What is the average packing ratio of DNA at metaphase? (Packing ratio = length of chromosome/length of DNA molecule therein.) How is this packing achieved? Answer: There is a total of 4 m ...
... set contains approximately 4 m of DNA. The average size of each chromosome during metaphase of mitosis is 13 m. What is the average packing ratio of DNA at metaphase? (Packing ratio = length of chromosome/length of DNA molecule therein.) How is this packing achieved? Answer: There is a total of 4 m ...
On Sexual Reproduction as a New Critique of the Theory of Natural
... than others? Almost certainly yes. Some varieties would have been inherently more stable than others. Certain molecules, once formed, would be less likely than others to break up again. �ese types would become relatively numerous in the soup, not only as a direct logical consequence of their ‘longev ...
... than others? Almost certainly yes. Some varieties would have been inherently more stable than others. Certain molecules, once formed, would be less likely than others to break up again. �ese types would become relatively numerous in the soup, not only as a direct logical consequence of their ‘longev ...
Building Risk-Optimal Portfolio Using Evolutionary Strategies
... Piotr Lipinski1 , Katarzyna Winczura2 , and Joanna Wojcik2 ...
... Piotr Lipinski1 , Katarzyna Winczura2 , and Joanna Wojcik2 ...
Complex inheritance of larval adaptation in Plutella
... P-strain (c) or C-strain grandparent (d) in the second row. Because of the expectation that alleles from the P-strain with differential survival would confer an advantage on pea-feeding individuals, we computed the one-tailed probability corresponding to tables with the observed value of a or greate ...
... P-strain (c) or C-strain grandparent (d) in the second row. Because of the expectation that alleles from the P-strain with differential survival would confer an advantage on pea-feeding individuals, we computed the one-tailed probability corresponding to tables with the observed value of a or greate ...
Identification of chromosome intervals from 129 and C57BL/6 mouse
... region on distal chromosome 1 and considered as a candidate gene for murine SLE.6 Therefore, backgroundderived genes can significantly contribute to the phenotype observed in knockout strains even when the mice have been extensively backcrossed onto the B6 strain, greatly complicating the interpreta ...
... region on distal chromosome 1 and considered as a candidate gene for murine SLE.6 Therefore, backgroundderived genes can significantly contribute to the phenotype observed in knockout strains even when the mice have been extensively backcrossed onto the B6 strain, greatly complicating the interpreta ...
Käfer, E. and D. Luk
... Non-complementing pairs were further checked for recombination in intercrosses. However, since the latter were often sterile, most mutants were simultaneously crossed to alcoy; csp-2 (FGSC 3434) and mapped further to linked markers (Table 1). They were routinely checked for fertility in homozygous c ...
... Non-complementing pairs were further checked for recombination in intercrosses. However, since the latter were often sterile, most mutants were simultaneously crossed to alcoy; csp-2 (FGSC 3434) and mapped further to linked markers (Table 1). They were routinely checked for fertility in homozygous c ...
Mapping Mendelian Factors Underlying Quantitative ... Using RFLP Linkage Maps Eric
... D2/16u:, provided that the following assumptions hold: (i) the QTLs have effects of equal magnitude, (ii) the QTLs are unlinked, and (iii) the alleles in the high strain all increase the phenotype, while those in the low strain decrease the phenotype. (To see this, recall that the variance explained ...
... D2/16u:, provided that the following assumptions hold: (i) the QTLs have effects of equal magnitude, (ii) the QTLs are unlinked, and (iii) the alleles in the high strain all increase the phenotype, while those in the low strain decrease the phenotype. (To see this, recall that the variance explained ...
Whose Genetic Information Is It Anyway?
... nih.gov/HGP/Reports/genetics-workplace.html> (Jan. 20, 1998) [hereinafter Dept. of Labor]. Scientist have found an estimated 3,000 to 4,000 diseases that are genetically linked, including Huntington's disease, cystic fibrosis and breast cancer. Id. at 2. Errors in an individual's genetic code have a ...
... nih.gov/HGP/Reports/genetics-workplace.html> (Jan. 20, 1998) [hereinafter Dept. of Labor]. Scientist have found an estimated 3,000 to 4,000 diseases that are genetically linked, including Huntington's disease, cystic fibrosis and breast cancer. Id. at 2. Errors in an individual's genetic code have a ...
4. Responding to environment Booklet TN
... 1. 13 bp deletion (has most serious consequences); 2. frameshift/alter reading frame; 3. genetic code is triplet/read in groups of 3 bases; 4. alters all amino acids (coded for) after the mutation; 5. 21 bp deletion causes 7 amino acids to be lost; 6. Substitution changes, one/no, amino acids; CREDI ...
... 1. 13 bp deletion (has most serious consequences); 2. frameshift/alter reading frame; 3. genetic code is triplet/read in groups of 3 bases; 4. alters all amino acids (coded for) after the mutation; 5. 21 bp deletion causes 7 amino acids to be lost; 6. Substitution changes, one/no, amino acids; CREDI ...
Population genetics
Population genetics is the study of the distribution and change in frequency of alleles within populations, and as such it sits firmly within the field of evolutionary biology. The main processes of evolution (natural selection, genetic drift, gene flow, mutation, and genetic recombination) form an integral part of the theory that underpins population genetics. Studies in this branch of biology examine such phenomena as adaptation, speciation, population subdivision, and population structure.Population genetics was a vital ingredient in the emergence of the modern evolutionary synthesis. Its primary founders were Sewall Wright, J. B. S. Haldane and Ronald Fisher, who also laid the foundations for the related discipline of quantitative genetics.Traditionally a highly mathematical discipline, modern population genetics encompasses theoretical, lab and field work. Computational approaches, often utilising coalescent theory, have played a central role since the 1980s.