Sequential follow up observations of a patient with rubella
... described previously.2 3 The viral antigens have also been described4 5 and were obtained from Microbiological Associates as the complement fixing antigen, except that up to 1987 the rubella antigen was obtained from Flow Laboratories. In 1989 and 1990, two additional viral antigens were routinely i ...
... described previously.2 3 The viral antigens have also been described4 5 and were obtained from Microbiological Associates as the complement fixing antigen, except that up to 1987 the rubella antigen was obtained from Flow Laboratories. In 1989 and 1990, two additional viral antigens were routinely i ...
2012 Medical Student Scholarship Winner – Christina Sarris
... chronic fatigue, patients have become symptomatic after combating a specific infectious disease. Thus, infectious agents have been suggested in many instances, yet there remains no single pathogen that can be identified in a significant proportion of cases. In 1985, two large studies of patients wit ...
... chronic fatigue, patients have become symptomatic after combating a specific infectious disease. Thus, infectious agents have been suggested in many instances, yet there remains no single pathogen that can be identified in a significant proportion of cases. In 1985, two large studies of patients wit ...
Hepatitis B or Hepatitis C Virus Infection Is a Risk Factor for Severe
... related to the intensity of the immunological response to highly active antiretroviral therapy (HAART). Nevertheless, our study had several limitations. First, a 1-month delay may be too short to assess the immunological response, and markers other than the peripheral CD4+ cell count might be more r ...
... related to the intensity of the immunological response to highly active antiretroviral therapy (HAART). Nevertheless, our study had several limitations. First, a 1-month delay may be too short to assess the immunological response, and markers other than the peripheral CD4+ cell count might be more r ...
1Laboratory of Complement Biology, New York Blood - HAL
... in Caucasians than in individuals of African descent. Not surprisingly, antibodies against these commons antigens are most frequently identified in SCD patients.8 Matching for E, C and K reduced the rate of alloimmunization in chronically transfused SCD patients from 3% to 0.5% per unit19 and is no ...
... in Caucasians than in individuals of African descent. Not surprisingly, antibodies against these commons antigens are most frequently identified in SCD patients.8 Matching for E, C and K reduced the rate of alloimmunization in chronically transfused SCD patients from 3% to 0.5% per unit19 and is no ...
Massive haemoptysis - e-SAFE
... This is a rapidly progressive glomerulonephritis associated with diffuse alveolar haemorrhage and the presence of antibodies directed against the glomerular basement membrane (Anti-GBM antibodies). These can be seen on immunofluorescence of a renal biopsy sample as IgG deposition along glomerular ca ...
... This is a rapidly progressive glomerulonephritis associated with diffuse alveolar haemorrhage and the presence of antibodies directed against the glomerular basement membrane (Anti-GBM antibodies). These can be seen on immunofluorescence of a renal biopsy sample as IgG deposition along glomerular ca ...
Review Article Thyroid dysfunction: an autoimmune aspect
... other cells, like it can alter cell signaling, migration, cytokine production, break peripheral tolerance and implicate autoimmune disease. Not only the pro-inflammatory cytokines provoked AITD or an inflammatory response, they alone can prevent the experimental autoimmune thyroiditis, suggested by ...
... other cells, like it can alter cell signaling, migration, cytokine production, break peripheral tolerance and implicate autoimmune disease. Not only the pro-inflammatory cytokines provoked AITD or an inflammatory response, they alone can prevent the experimental autoimmune thyroiditis, suggested by ...
HELLP syndrome: a complication or a new autoimmune
... Reumatologia, Dipartimento di Medicina Interna e Specialità Mediche, Sapienza Università di Roma, Rome, Italy ...
... Reumatologia, Dipartimento di Medicina Interna e Specialità Mediche, Sapienza Università di Roma, Rome, Italy ...
A biologically important single nucleotide poly
... the patients. Comparison of rare allele carriage between controls and patients revealed no significant difference p = 0.13. This was also the case in shared epitope negative individuals p = 0.92. Conclusion. The TLR-4 +896 poly morphism does not appear to influence susceptibility to rheumatoid arthr ...
... the patients. Comparison of rare allele carriage between controls and patients revealed no significant difference p = 0.13. This was also the case in shared epitope negative individuals p = 0.92. Conclusion. The TLR-4 +896 poly morphism does not appear to influence susceptibility to rheumatoid arthr ...
Clinical Synopsis A 32year old female presented with a four year
... melanoma arising in vitiliginous lesion. The pathologic mechanism of vitiligo is not clearly known. Complex factors involving cellular and humoral immunity, toxic metabolites and genetic factors partly contribute to its pathogenesis. Ciuet al5 demonstrated that antibodies to melanocytes were present ...
... melanoma arising in vitiliginous lesion. The pathologic mechanism of vitiligo is not clearly known. Complex factors involving cellular and humoral immunity, toxic metabolites and genetic factors partly contribute to its pathogenesis. Ciuet al5 demonstrated that antibodies to melanocytes were present ...
Infectious Complications With the Use of Biologic Response
... Response Modifiers in Infants and Children. Pediatrics. 2016;138(2):e20161209 ...
... Response Modifiers in Infants and Children. Pediatrics. 2016;138(2):e20161209 ...
Superantigens and Their Role in Autoimmune Disorders
... IL-2 receptor positive T cells with the idea that autoreactive T cells in the joints would be activated spontaneously. Three gene families were found in a majority of the synovial samples analyzed. Given that in many instances the Vβ repertoires were dominates by a single rearrangement and given the ...
... IL-2 receptor positive T cells with the idea that autoreactive T cells in the joints would be activated spontaneously. Three gene families were found in a majority of the synovial samples analyzed. Given that in many instances the Vβ repertoires were dominates by a single rearrangement and given the ...
Abeloff`s Clinical Oncology Update
... Abeloff’s Clinical Oncology https://www.surveymonkey.com/s/Abeloffupdate ...
... Abeloff’s Clinical Oncology https://www.surveymonkey.com/s/Abeloffupdate ...
Human Immunodeficiency Virus (HIV) Tat
... Human Immunodeficiency Virus (HIV) Tat-reactive Antibodies Present in Normal HIV-negative Sera and Depleted in HIV-positive Sera. Identification of the Epitope By Toby C. Rodman,*~Fred H. Pruslin,* Stephen E. To,* and Ronald Winston~ From the "Laboratory of Cell Biology, The Rockefeller University, ...
... Human Immunodeficiency Virus (HIV) Tat-reactive Antibodies Present in Normal HIV-negative Sera and Depleted in HIV-positive Sera. Identification of the Epitope By Toby C. Rodman,*~Fred H. Pruslin,* Stephen E. To,* and Ronald Winston~ From the "Laboratory of Cell Biology, The Rockefeller University, ...
Principles of Transplantation
... antigen-specific damage to the graft directly or via the release of cytotoxic antibodies • May also occur via stimulation of Th2 cells with production of IL-4/IL-5 promoting the production of Bcells and release of graft specific antibodies ...
... antigen-specific damage to the graft directly or via the release of cytotoxic antibodies • May also occur via stimulation of Th2 cells with production of IL-4/IL-5 promoting the production of Bcells and release of graft specific antibodies ...
Management Of Cold Haemolytic Syndrome
... A study of 15 patients with chronic cold agglutinin disease (Ulvestad et al, 1999) showed that all had an IgM j cold agglutinin encoded by IGHV4-34 (the VH4-34 gene). Seven had reduced concentrations of T cells. CD56 and CD19 were increased in seven and three patients respectively and clonal j-posit ...
... A study of 15 patients with chronic cold agglutinin disease (Ulvestad et al, 1999) showed that all had an IgM j cold agglutinin encoded by IGHV4-34 (the VH4-34 gene). Seven had reduced concentrations of T cells. CD56 and CD19 were increased in seven and three patients respectively and clonal j-posit ...
Epstein-Barr Virus (Powerpoint presentation)
... agglutinate antigens on RBCs from different mammalian species IM heterophile Ab (IgM) does not react with EBV- specific antigens characterized by its ability to react with beef, sheep and horse RBCs The antigen that stimulates this heterophile ab is unknown ...
... agglutinate antigens on RBCs from different mammalian species IM heterophile Ab (IgM) does not react with EBV- specific antigens characterized by its ability to react with beef, sheep and horse RBCs The antigen that stimulates this heterophile ab is unknown ...
Autoimmunity and Apoptosis – Therapeutic Implications Iran Rashedi , Soumya Panigrahi
... of T-cells [20, 21] or when they are present in immune privileged sites, physically separated from T-lymphocytes (i.e. lens, some compartments within the testis) [22, 23]. As long as these regulatory mechanisms work efficiently, self-reactive T-cells do not cause any disease. However, this self-tole ...
... of T-cells [20, 21] or when they are present in immune privileged sites, physically separated from T-lymphocytes (i.e. lens, some compartments within the testis) [22, 23]. As long as these regulatory mechanisms work efficiently, self-reactive T-cells do not cause any disease. However, this self-tole ...
report from the Study Group f
... rate of progression of joint destruction and the development of extra-articular manifestations of RA (eg, cardiovascular disease and pulmonary fibrosis) that could be identified in individuals ‘at risk’ of RA. Factors related to remission would also be of interest. The possible influence of the timing ...
... rate of progression of joint destruction and the development of extra-articular manifestations of RA (eg, cardiovascular disease and pulmonary fibrosis) that could be identified in individuals ‘at risk’ of RA. Factors related to remission would also be of interest. The possible influence of the timing ...
Synergistic Effect of Intravenous Immunoglobulins and Iodinated
... Thrombocytopenic Purpura.1 The most common side effect of IVIG includes the early complications such as flushing, headache, nausea, vomiting, myalgia, chest pain, hypertension, fever and chills.2,3 Severe adverse reactions are rare.4 Acute renal failure (ARF) is a rare but significant complication o ...
... Thrombocytopenic Purpura.1 The most common side effect of IVIG includes the early complications such as flushing, headache, nausea, vomiting, myalgia, chest pain, hypertension, fever and chills.2,3 Severe adverse reactions are rare.4 Acute renal failure (ARF) is a rare but significant complication o ...
Growth Hormone Deficiency in Fungal Exposure
... patients with CRS. Other studies have reported that treatment with intranasal antifungal drugs can cause complete or partial remission of symptoms in many rhinosinusitis patients (Ponikau et al., 2002; Ricchetti et al., 2002; Sherris et al., 2005). Fungal antigens activate helper T-lymphocytes in th ...
... patients with CRS. Other studies have reported that treatment with intranasal antifungal drugs can cause complete or partial remission of symptoms in many rhinosinusitis patients (Ponikau et al., 2002; Ricchetti et al., 2002; Sherris et al., 2005). Fungal antigens activate helper T-lymphocytes in th ...
| Specific antigen(s) in sarcoidosis: a link to autoimmunity?
... This work has several implications and raises numerous questions. First of all, the current and the preceding publications of the Karolinska group demonstrate an autoantigenic component in the pathogenesis of sarcoidosis. However, the current report involves only patients with Löfgren syndrome and i ...
... This work has several implications and raises numerous questions. First of all, the current and the preceding publications of the Karolinska group demonstrate an autoantigenic component in the pathogenesis of sarcoidosis. However, the current report involves only patients with Löfgren syndrome and i ...
acute systemic inflammation
... assay [19]. A very sensitive bio-assay for HGF was developed, and this assay did not respond to IL-1, indicating that HGF had to be another cytokine. After cloning of cDNA, HGF was discovered to be identical with a new cytokine named interleukin-6 [20]. In many in vitro and in vivo studies that foll ...
... assay [19]. A very sensitive bio-assay for HGF was developed, and this assay did not respond to IL-1, indicating that HGF had to be another cytokine. After cloning of cDNA, HGF was discovered to be identical with a new cytokine named interleukin-6 [20]. In many in vitro and in vivo studies that foll ...
Variations in Dinitrochlorobenzene Responsivity in Untreated Leprosy
... time of DNCB sensitization; those of Turk and Waters ( 11 ) were treated and had a history of EN L but evidently not active ENL at the time of sensitization. In leprosy the requisite conditions and effector mechanisms responsible for impaired DNCB responsivity are not known. However, in the present ...
... time of DNCB sensitization; those of Turk and Waters ( 11 ) were treated and had a history of EN L but evidently not active ENL at the time of sensitization. In leprosy the requisite conditions and effector mechanisms responsible for impaired DNCB responsivity are not known. However, in the present ...
- Salford Royal NHS Foundation Trust
... cytomegalovirus and dermatomal varicella zoster (VZV). Although the clinical follow-up of ICL patients is dominated by HPV, VZV, and mucosal candidiasis, more serious and potentially lethal subsequent opportunistic infections may occur, such as PCP, progressive multifocal leukoencephalopathy (PML) c ...
... cytomegalovirus and dermatomal varicella zoster (VZV). Although the clinical follow-up of ICL patients is dominated by HPV, VZV, and mucosal candidiasis, more serious and potentially lethal subsequent opportunistic infections may occur, such as PCP, progressive multifocal leukoencephalopathy (PML) c ...
Reproductive Immunology: Biomarkers of
... Blocking or Incomplete Antibodies Blocking and/or incomplete antibodies have long been suspected as being important manifestations of immunity in reproduction and cancer research. Techniques were developed many years ago to identify antibodies that were not serologically detectable by conventional a ...
... Blocking or Incomplete Antibodies Blocking and/or incomplete antibodies have long been suspected as being important manifestations of immunity in reproduction and cancer research. Techniques were developed many years ago to identify antibodies that were not serologically detectable by conventional a ...