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Mechanism of Binding to Ebola Virus
Mechanism of Binding to Ebola Virus

... nonhuman primate models and have been used under emergency compassionate-treatment protocols in human patients. However, the amino acids that form the detailed binding epitopes for the MAbs in the ZMapp, ZMAb, and the related MB-003 cocktails have yet to be identified. Other binding properties that ...
Oh Lord, please don`t let me be misunderstood
Oh Lord, please don`t let me be misunderstood

... He refers to his work on vitamin levels without mentioning his disparaging dismissal of vitamin supplementation or his unsupported conclusion that “many” people with “CFS” are taking vitamin B supplementation with no evidence of benefit (JRSM 1999:92:183-185). Wessely concedes that he has changed hi ...
Headache ‘THE RED FLAGS’
Headache ‘THE RED FLAGS’

... • Common cause of referral to Neurology • Prevalence: Range 30.1 to 53.2% • Recurring headache – 3% for 7 years old – 15% for 15 years old – Before puberty: Boys > Girls – After puberty : Girls > Boys ...
1. Light Chain
1. Light Chain

... specificity of antibodies. That is, they will bind to one epitope. The clone of B-cells that derive from one original B-cell will all make the same specificity. Biologic Activity: the ability to trigger protective physiological activities usually after binding to antigen. This would include:  opson ...
VCG1 : preliminary results
VCG1 : preliminary results

... The use of irradiated ATC vaccines is considered an advantage, given the lack of knowledge regarding the relevant tumor associated antigens (TAAs) in glioma. Furthermore, injection of these irradiated ATC allows an antigenic treatment in vivo without manipulation of dendritic cells ex vivo. To rende ...
related (Pogosta) virus in different parts of Finland
related (Pogosta) virus in different parts of Finland

... the RF by absorption, 15 sera were positive for Pogosta virus antibodies of IgM class. The prevalence of antibodies against Pogosta virus among the 1850 persons who were suspected to have some viral infection was highest in western Finland 15% (51) and lowest in northern Finland 6% (26). In eastern ...
Workshop  on Bronchoalveolar  lavage: in and  clinical  application
Workshop on Bronchoalveolar lavage: in and clinical application

... The repeatability of BAL makes it ideal for monitoring changes in pulmonary inflammatory cells and components during disease progression and therapy. We reported our frndings for 32 CFA patients with a mean follow-up period of 4 yrs [10]. Of 15 patients on highdose prednisolone, those showing mainta ...
Relationship between chronic inflammation and depression.
Relationship between chronic inflammation and depression.

... Different models for Inflammasome activation by DAMPs have been proposed.11 One way is dependent on the stimulation of the purinergic type 2X7 receptors (P2X7*) by ATP*.13,9 This receptors have been found in microglial and blood cells. The mechanisms by which stress produces ATP is not completely un ...
Contaminant Host Cell Derived Protein Assay | Molecular Devices
Contaminant Host Cell Derived Protein Assay | Molecular Devices

... specific cell line and specific purification process used, proprietary polyclonal anti-HCP antibodies are required for sensitive, specific and stoichiometric recognition of the antigen mixture potentially present in the final bulk product. A generic anti-HCP antibody can only be used to support the optim ...
Innate Immune Responses
Innate Immune Responses

... Rapid and systemic innate immune responses to an adenoviral HIV vaccine Erica Andersen-Nissen McElrath Lab Fred Hutchinson Cancer Research Center ...
ABSTRACT - European Medical Journal
ABSTRACT - European Medical Journal

... Liver: The hallmark of the liver manifestation of ACLF is hyperbilirubinaemia and coagulopathy. Hyperbilirubinaemia arises as a result of reduced detoxification function of the liver. In addition, the reduction in the liver’s synthetic function leads to a decrease in the production of coagulation fa ...
Respiratory disorders in common variable immunodeficiency
Respiratory disorders in common variable immunodeficiency

Immunoglobulin Structure
Immunoglobulin Structure

... myeloma). Is the presence of an M-component in serum diagnostic of multiple myeloma? No. M-component appear in the blood as people age. About 10% of healthy individuals in the ninth decade of live have M-component. This is called benign monoclonal gammopathy. Without bone lesions and presence of man ...
Intracranial Cryptococcosis in lmmunocompromised Patients:
Intracranial Cryptococcosis in lmmunocompromised Patients:

... nonenhancing lesions in three of 29, enhancing lesions in two of 20, and foci of leptomeningeal calcification in two of 29. Ten patients had both CT and MR studies, and four received gadopentetate dimeglumine. Among these 10 patients, five had normal CT studies and one showed moderate central atroph ...
Autoimmune diseases: genes, bugs and failed regulation
Autoimmune diseases: genes, bugs and failed regulation

... potentially dangerous self-reactive cells in check: clonal ignorance, deletion, anergy, immune deviation and suppression13. However, it is still unclear how important any of these mechanisms are in preventing autoimmune disease. Nevertheless, a number of examples from mouse models (and a few from pa ...
Risk groups for clinical complications of norovirus
Risk groups for clinical complications of norovirus

... One patient, suffering from ventricular tachycardias, developed three episodes of ventricular tachycardias and needed a cardioversion. Another patient could not reach the bathroom in time, slipped while vomiting and fell, suffering bruises. In two renal transplant patients, immunosuppressive therapy ...
antigen- antibody reactions - SOUTHERN MEDICAL UNIVERSITY
antigen- antibody reactions - SOUTHERN MEDICAL UNIVERSITY

... serum. The spread pattern in the experimental series indicates positive hemagglutination through tube 3. ...
Oral ulcerations
Oral ulcerations

... causative – Hormonal:  occurs at premenstrual days  improved during pregnancy ...
Vaccination of Patients with Small-Cell Lung Cancer with Synthetic
Vaccination of Patients with Small-Cell Lung Cancer with Synthetic

... carboplatin, with concurrent thoracic radiation added for patients with limited-stage disease. In the majority of cases, patients derive substantial tumor reduction with this treatment, and for about 20 to 25% of patients with limited-stage disease, this can represent curative therapy. However, the ...
Pityriasis Amiantacea:Its Clinical Aspects, Causes and Associations
Pityriasis Amiantacea:Its Clinical Aspects, Causes and Associations

... 50(65.78%) females. Their ages ranged between 3 months to 68 years and the median was 13 years. Full history and detailed clin ical examination was done for each patient. Swab for cu lture and skin scrapping as well as hair p lucking for mycological examination to detect any bacterial and fungal inf ...
Antibody Structure and B Cell Diversity
Antibody Structure and B Cell Diversity

... * Part of antigen to which antibody binds * Antigenic determinant (Epitope) ...
5 May 2015 Myalgic Encephalomyelitis/ Chronic Fatigue Syndrome
5 May 2015 Myalgic Encephalomyelitis/ Chronic Fatigue Syndrome

... Symptoms are adverse experiences or feelings described by a patient. They are therefore subjective and the process of eliciting a pattern of symptoms from a patient is known as “taking a history”. Examples of symptoms would be headache, nausea or breathlessness. Signs (sometimes known as physical si ...
Many Gulf War illnesses may be autoimmune disorders caused
Many Gulf War illnesses may be autoimmune disorders caused

... Overlapping multi-system, multi-organ illnesses that seem diffuse and hard to pin to a single cause, may simply be the response one would expect the immune system to produce when numerous tissues were damaged or affected by a relatively small number of chemicals or other ‘causes’. The process that p ...
Autoimmune Diseases
Autoimmune Diseases

... hemolytic anemia, Type 1 diabetes, glomerulonephritis, SLE ...
Ws_ch20e_Ts
Ws_ch20e_Ts

... STS connection 20.2 Stories of the development of vaccination (Student’s Book 3 p.95; Activity Book 3 p.45) Section concept diagram (Student’s Book 3 p.96) Quick check (Student’s Book 3 p.96) STS connection 20.3 Relation of immunization programmes to the control of infectious diseases (Student’s Boo ...
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Autoimmune encephalitis

Autoimmune encephalitis is a type of encephalitis that can result from a number of autoimmune diseases including: Rasmussen encephalitisSystemic lupus erythematosusBehcet's diseaseHashimoto's encephalopathyand Autoimmune limbic encephalitis↑
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