Intestinal mucosal barrier function in health and disease
... of specific transporters. Accordingly, direct epithelial cell damage, such as that induced by mucosal irritants or cytotoxic agents, including some drugs used for cancer chemotherapy, results in a marked loss of barrier function. However, in the presence of an intact epithelial cell layer, the parac ...
... of specific transporters. Accordingly, direct epithelial cell damage, such as that induced by mucosal irritants or cytotoxic agents, including some drugs used for cancer chemotherapy, results in a marked loss of barrier function. However, in the presence of an intact epithelial cell layer, the parac ...
The relationship of mucosal bacteria to duodenal histopathology
... and those demonstrating an abnormal mucosa-associated flora, considered to interact most closely with the innate immune system, in people with IBD (Kleessen et al., 2002; Swidsinski et al., 2005). Knowledge of genetic susceptibility and the enteric microflora in cats with IBD is limited, with some s ...
... and those demonstrating an abnormal mucosa-associated flora, considered to interact most closely with the innate immune system, in people with IBD (Kleessen et al., 2002; Swidsinski et al., 2005). Knowledge of genetic susceptibility and the enteric microflora in cats with IBD is limited, with some s ...
Patients with oral erosive and cutaneous lichen planus may have
... Objective: The aim of this study is to verify whether stratified epithelium-specific antinuclear antibodies are present in the sera of patients with erosive oral lichen planus and cutaneous lichen planus. Methods: We studied the pre-immune and immune serum of a rabbit immunized with a peptide corres ...
... Objective: The aim of this study is to verify whether stratified epithelium-specific antinuclear antibodies are present in the sera of patients with erosive oral lichen planus and cutaneous lichen planus. Methods: We studied the pre-immune and immune serum of a rabbit immunized with a peptide corres ...
Inflammation - UK - Tree of Light Publishing
... the body’s initial response to irritation, tissue damage or infection ...
... the body’s initial response to irritation, tissue damage or infection ...
Small Bowel Bleeding and Capsule Endoscopy
... accurately describe to the surgeon for removal. Finally the small bowel is more then 17 feet long, which is much longer than any of the instruments currently available. ...
... accurately describe to the surgeon for removal. Finally the small bowel is more then 17 feet long, which is much longer than any of the instruments currently available. ...
SMALL BOWEL BLEEDING AND CAPSULE ENDOSCOPY
... enteroclysis. The small bowel follow-through test is a series of abdominal X-rays that are taken at different times after a patient drinks a white chalky fluid called barium that shows up clearly on X-rays. The test allows the doctor to see the lining of the intestine for any irregularities as the b ...
... enteroclysis. The small bowel follow-through test is a series of abdominal X-rays that are taken at different times after a patient drinks a white chalky fluid called barium that shows up clearly on X-rays. The test allows the doctor to see the lining of the intestine for any irregularities as the b ...
Ginkgo biloba extract EGb 761 has anti
... The standardized, well-characterized G.biloba extract, EGb 761, is a putative anti-inflammatory agent. To test whether EGb 761 abates inflammation in vitro, we examined its ability to attenuate inflammatory players. Figure 1A shows that IFN-c activates iNOS in ANA-1 mouse macrophages and that this i ...
... The standardized, well-characterized G.biloba extract, EGb 761, is a putative anti-inflammatory agent. To test whether EGb 761 abates inflammation in vitro, we examined its ability to attenuate inflammatory players. Figure 1A shows that IFN-c activates iNOS in ANA-1 mouse macrophages and that this i ...
Immunity and Gastrointestinal Disease: A Role for Lymphatic Vessels
... [31]. While much is known about the pathology surrounding IBD, little is known about its precise etiology, which is believed to be multifactorial, involving environment, genetics and immune dysregulation [32]. DCs isolated from the lamina propria of Crohn’s disease patients showed elevated expressio ...
... [31]. While much is known about the pathology surrounding IBD, little is known about its precise etiology, which is believed to be multifactorial, involving environment, genetics and immune dysregulation [32]. DCs isolated from the lamina propria of Crohn’s disease patients showed elevated expressio ...
cholangitis/cholangiohepatitis syndrome
... Antibiotics that kill bacteria (known as “bactericidal antibiotics”)—against intestinal bacterial opportunists (bacteria that usually do not cause disease, but are able to cause disease because the animal’s body and/or immune system has been weakened by some other disease process); amoxicillin-cla ...
... Antibiotics that kill bacteria (known as “bactericidal antibiotics”)—against intestinal bacterial opportunists (bacteria that usually do not cause disease, but are able to cause disease because the animal’s body and/or immune system has been weakened by some other disease process); amoxicillin-cla ...
Cholangitis/ Cholangiohepatitis Syndrome
... Antibiotics that kill bacteria (known as “bactericidal antibiotics”)—against intestinal bacterial opportunists (bacteria that usually do not cause disease, but are able to cause disease because the animal’s body and/or immune system has been weakened by some other disease process); amoxicillin-cla ...
... Antibiotics that kill bacteria (known as “bactericidal antibiotics”)—against intestinal bacterial opportunists (bacteria that usually do not cause disease, but are able to cause disease because the animal’s body and/or immune system has been weakened by some other disease process); amoxicillin-cla ...
PowerPoint - Non-Regenerative Anemia
... Blood loss anemia is first strongly regenerative, then non-regenerative as IDA develops Anemia varies from mild to severe Poikilocytosis and hypochromasia are typical Hypoproteinemia often present Anemia won’t budge until iron is supplemented, even if chronic blood loss is corrected Rapid improvemen ...
... Blood loss anemia is first strongly regenerative, then non-regenerative as IDA develops Anemia varies from mild to severe Poikilocytosis and hypochromasia are typical Hypoproteinemia often present Anemia won’t budge until iron is supplemented, even if chronic blood loss is corrected Rapid improvemen ...
Folate Deficiency
... Inflammatory and rheumatologic disease. Renal disease. Pathophysiology A mild hemolytic component is often present, red blood cell survival is moderately decreased. Erythropoietin levels are normal or slightly elevated but are inappropriately low for the degree of anemia, erythropoietin leve ...
... Inflammatory and rheumatologic disease. Renal disease. Pathophysiology A mild hemolytic component is often present, red blood cell survival is moderately decreased. Erythropoietin levels are normal or slightly elevated but are inappropriately low for the degree of anemia, erythropoietin leve ...
Search for the laboratory parameters of
... the results of experimental studies and clinical observations provide evidence suggesting the role of low-grade inflammation and immune activation as plausible contributors to IBS manifestations [2,3]. Previous infections and persistent mucosal inflammation are thought to play an important part in t ...
... the results of experimental studies and clinical observations provide evidence suggesting the role of low-grade inflammation and immune activation as plausible contributors to IBS manifestations [2,3]. Previous infections and persistent mucosal inflammation are thought to play an important part in t ...
cholangitis_cholangiohepatitis_syndrome
... • ”Cholangitis” is inflammation of the bile duct or the biliary tree • “Cholangiohepatitis” is inflammation of biliary structures and surrounding liver tissue • Cholangitis/cholangiohepatitis syndrome occurs primarily in cats; it is classified as “suppurative” or “nonsuppurative” (lymphoplasmacytic, ...
... • ”Cholangitis” is inflammation of the bile duct or the biliary tree • “Cholangiohepatitis” is inflammation of biliary structures and surrounding liver tissue • Cholangitis/cholangiohepatitis syndrome occurs primarily in cats; it is classified as “suppurative” or “nonsuppurative” (lymphoplasmacytic, ...
Cholangitis/ Cholangiohepatitis Syndrome
... • ”Cholangitis” is inflammation of the bile duct or the biliary tree • “Cholangiohepatitis” is inflammation of biliary structures and surrounding liver tissue • Cholangitis/cholangiohepatitis syndrome occurs primarily in cats; it is classified as “suppurative” or “nonsuppurative” (lymphoplasmacytic, ...
... • ”Cholangitis” is inflammation of the bile duct or the biliary tree • “Cholangiohepatitis” is inflammation of biliary structures and surrounding liver tissue • Cholangitis/cholangiohepatitis syndrome occurs primarily in cats; it is classified as “suppurative” or “nonsuppurative” (lymphoplasmacytic, ...
Complex Structure Function Claims
... ‘‘carminative (antispasmodic) properties’’ or as a result of its ‘‘anti-inflammatory effect on the gastrointestinal tract.’’ – the term “anti-inflammatory” is strongly associated with treatment of diseases ...
... ‘‘carminative (antispasmodic) properties’’ or as a result of its ‘‘anti-inflammatory effect on the gastrointestinal tract.’’ – the term “anti-inflammatory” is strongly associated with treatment of diseases ...
High prevalence of abnormal gastrointestinal permeability in
... Purpose: Abnormal gastrointestinal permeability (GIP) has been implicated in a number of diseases, including chronic intestinal inflammatory disorders such as Crohn’s as well as non-intestinal immunologic diseases such as diabetes and multiple sclerosis. Although evidence in the literature demonstra ...
... Purpose: Abnormal gastrointestinal permeability (GIP) has been implicated in a number of diseases, including chronic intestinal inflammatory disorders such as Crohn’s as well as non-intestinal immunologic diseases such as diabetes and multiple sclerosis. Although evidence in the literature demonstra ...
INTESTINAL OBSTRUCTION
... the abdominal cavity, thereby leading to peritonitis. 7. Closed-loop obstruction is a condition in which the intestinal segment is occluded at both ends, preventing either the downward passage or the regurgitation of intestinal contents. ...
... the abdominal cavity, thereby leading to peritonitis. 7. Closed-loop obstruction is a condition in which the intestinal segment is occluded at both ends, preventing either the downward passage or the regurgitation of intestinal contents. ...
Treatment of Crohn`s Disease with Cannabis: An
... surgery, and hospitalization before and after cannabis use in 30 patients (26 males) with CD. Disease activity was assessed by the Harvey Bradshaw index for Crohn’s disease. Results: Of the 30 patients 21 improved significantly after treatment with cannabis. The average Harvey Bradshaw index improve ...
... surgery, and hospitalization before and after cannabis use in 30 patients (26 males) with CD. Disease activity was assessed by the Harvey Bradshaw index for Crohn’s disease. Results: Of the 30 patients 21 improved significantly after treatment with cannabis. The average Harvey Bradshaw index improve ...
Possible Applications Basic overview
... known cure, there is a growing and urgent need for more specific and effective therapeutics. Researchers from Trinity College Dublin have discovered a novel method of suppressing the induction of a specific subtype of T cell responses in vivo, which are fundamental players in autoimmune and inflamma ...
... known cure, there is a growing and urgent need for more specific and effective therapeutics. Researchers from Trinity College Dublin have discovered a novel method of suppressing the induction of a specific subtype of T cell responses in vivo, which are fundamental players in autoimmune and inflamma ...
The physiology of colonic hydrotherapy - E
... and a large proportion of this is actually dietary fibre. It is therefore wrong to think that the primary function of the left colon and rectum as the collection of nutrients and fluids from digested material. Nutrients are absorbed mainly by the small intestines and the right colon [8]. About 1.5 l ...
... and a large proportion of this is actually dietary fibre. It is therefore wrong to think that the primary function of the left colon and rectum as the collection of nutrients and fluids from digested material. Nutrients are absorbed mainly by the small intestines and the right colon [8]. About 1.5 l ...
treatment of crohn’s disease with cannabis: an Observational study Original articles
... disease in humans. The results indicate that cannabis may have a positive effect on disease activity, as reflected by reduction in disease activity index and in the need for other drugs and surgery. Prospective placebo-controlled studies are warranted to fully evaluate the efficacy and side effects ...
... disease in humans. The results indicate that cannabis may have a positive effect on disease activity, as reflected by reduction in disease activity index and in the need for other drugs and surgery. Prospective placebo-controlled studies are warranted to fully evaluate the efficacy and side effects ...
Ulcerative colitis
Ulcerative colitis (Colitis ulcerosa, UC) is a form of inflammatory bowel disease (IBD) that causes inflammation and ulcers in the colon. The disease is a type of colitis, which is a group of diseases that cause inflammation of the colon, the largest section of the large intestine, either in segments or completely. The main symptom of active disease is usually constant diarrhea mixed with blood, of gradual onset. IBD (Crohn's disease (CD) and ulcerative colitis (UC)) is often confused with irritable bowel syndrome (IBS).Ulcerative colitis has much in common with Crohn's disease, another form of IBD, but what sets it apart from Crohn's disease is that ulcerative colitis, as its name suggests, only affects the colon and rectum, leaving the rest of the gastrointestinal tract unscathed, while Crohn's disease can affect the whole GI tract from mouth to anus. Also, surgical removal of the colon and rectum cures ulcerative colitis, which actually means the disease does not recur after surgery, unlike Crohn's disease, which has a tendency to recur after surgery to remove the abnormal part of the bowel and connect the healthy ends. Ulcerative colitis is an intermittent disease, with periods of exacerbated symptoms, and periods that are relatively symptom-free. Although the symptoms of ulcerative colitis can sometimes diminish on their own, the disease usually requires treatment to go into remission. Ulcerative colitis has an incidence of 1 to 20 cases per 100,000 individuals per year, and a prevalence of 8 to 246 per 100,000 individuals.The disease is more prevalent in northern countries of the world, as well as in northern areas of individual countries or other regions. Rates tend to be higher in more affluent countries, which may indicate the increased prevalence is due to increased rates of diagnosis. It may also indicate that an industrial or Western diet and lifestyle increases the prevalence of this disease, including symptoms which may or may not be related to ulcerative colitis. Although UC has no known cause, there is a presumed genetic component to susceptibility. The disease may be triggered in a susceptible person by environmental factors. Dietary modification may reduce the discomfort of a person with the disease.Like Crohn's disease, ulcerative colitis is both classed as and managed as an autoimmune disease. Management is with anti-inflammatory drugs, immunosuppression, and biological therapy targeting specific components of the immune response. Colectomy (partial or total removal of the large bowel through surgery) is occasionally necessary if the disease is severe, does not respond to treatment, or if significant complications develop. A total proctocolectomy (removal of the entirety of the large bowel and rectum) can cure ulcerative colitis as the disease only affects the large bowel and rectum and does not recur after removal of the latter. While extra-intestinal symptoms will remain, complications may develop.