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F2005B02526 F2005B02526
F2005B02526 F2005B02526

... For the purposes of this Statement of Principles: “a dura mater graft” means a surgical procedure where a dura mater graft from a human donor is used; “blood products” means material extracted from human blood; “bovine spongiform encephalopathy infection” also known as “mad cow disease”, means a dis ...
The Avian Immune System - EDIS
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... the T-lymphocytes, begin as the same stem cells as the B-cells. However, the T-lymphocytes are programmed in the thymus rather than the BF. The T-lymphocytes include a more heterogeneous population than the B-cells. Some T-cells act by producing lymphokines (over 90 different ones have been identifi ...
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... dermatomyositis, a skin rash comes before or at the ...
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Transverse Myelopathy - Viktor`s Notes for the Neurosurgery Resident
Transverse Myelopathy - Viktor`s Notes for the Neurosurgery Resident

... most definitive support is for a vascular cause (angiogram may show the absence of radicular artery and no artery of Adamkiewicz).  altered venous return that occurs from lying prone for prolonged periods of time on a surfboard can contribute to vascular insufficiency.  occlusion by embolus or vas ...
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Alzheimer`sDisease_Nguyen

... and an increase in the erythrocyte sedimentation rate (ESR) Variations of the HLA-B gene increase the risk of developing ankylosing spondylitis, although it is not a diagnostic test. Those with the HLA-B27 variant are at a higher risk than the general population of developing the disorder. HLA-B27, ...
EPB PHC 6000 EPIDEMIOLOGY FALL, 1997
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Systemic lupus erythematosus

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... one of the Institute's two large studies of chronic Lyme disease and co-authored the new report. The new technique, developed by Roland Martin, M.D., of the National Institute of Neurological Disorders and Stroke (NINDS), Richard Simon, Ph.D., of the National Cancer Institute (NCI), together with Cl ...
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... SLE and only rarely in other connective tissue disorders. • Hence, it is considered to be relatively specific for SLE and the American Rheumatoid Arthritis Association considers it a criterion in the diagnosis of this disease. • The normal reference range is 0.00-0.05 IU/ml or 70-200 units. • They m ...
Autoimmunity
Autoimmunity

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... Autoimmune disease occurs when an immune response attacks our own tissues. Like all adaptive immune responses, it is focused on specific antigens by T-cell receptors and B cell receptors. In contrast to infection, the antigens that these cells recognise are processed from proteins within the target ...
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... was associated with an evident improvement in the immune status, namely consisting of a decrease in the number of T regulatory lymphocytes, which are the main cells responsible for the suppression of the anticancer immunity. Conclusion: This preliminary study shows that a biological anticancer regim ...
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... • In females, there are highly variable levels of enzyme activity and broader range of clinical symptoms • Most females are affected; in various studies, 12% of Fabry´s patients on dialysis are women ...
Case Study 1- What is the basis of autoimmune diseases (list 4
Case Study 1- What is the basis of autoimmune diseases (list 4

... to mylein basic protein, the inflammation causes damage to the myelin sheath and the axons. When the inflammation response starts to resolve plaques and diffuse lesions are present, resulting in the demyelinating process involving the white matter of the CNS. The demyelination causes conduction bloc ...
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Neuromyelitis optica

Neuromyelitis optica (NMO), also known as Devic's disease or Devic's syndrome, is a heterogeneous condition consisting of the simultaneous inflammation and demyelination of the optic nerve (optic neuritis) and the spinal cord (myelitis). It can be monophasic or recurrent.Currently at least two different causes are proposed based on the presence of autoantibodies against AQP4. AQP4+ NMO is currently considered an autoimmune disease (autoimmune astrocytopathy, or autoimmune astrocytic channelopathy) in which a person's own immune system attacks the astrocytes of the optic nerves and spinal cord. The cause of the AQP4- variants is unknown.Although inflammation may also affect the brain, the lesions are different from those observed in the related condition, multiple sclerosis. Spinal cord lesions lead to varying degrees of weakness or paralysis in the legs or arms, loss of sensation (including blindness), and/or bladder and bowel dysfunction.Devic's disease is now studied along a collection of similar diseases called ""Neuromyelitis optica spectrum diseases"". Some cases of this spectrum resemble multiple sclerosis (MS) in several ways, but require a different course of treatment for optimal results.In 2004, NMO-IgG (currently known as Anti-AQP IgG) was first described leading to the distinction between positive and negative cases.In Anti-AQP positive variants, CNS astrocytes, which are the basis for the glymphatic system are the target of the autoimmune attack. NMO-IgG-negative cases are less understood. It seems currently that astrocytes are spared in these IgG negative cases
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