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Molecular role of GATA binding protein 4 (GATA
Molecular role of GATA binding protein 4 (GATA

... proximal GATA-4-binding site in the cardiac TnI gene is necessary for the transcriptional activation of this gene in vitro, while other sites for GATA-4 DNA binding may contribute to the regulation of this gene [14]. Otherwise, it has been documented that MEK1-ERK1/2 signaling regulates the hypertro ...
Cell Structure - The Physics Teacher.ie
Cell Structure - The Physics Teacher.ie

... 2. Identify the parts of an animal cell as seen under light microscope 3. Give the function of each of the following parts: Cell wall, cell membrane, nucleus, cytoplasm, vacuole and chloroplast 4. Identify the ultra structure and give the function of each of the following cell parts: Cell membrane, ...
and y-crystallin X - Prof. N. Srinivasan
and y-crystallin X - Prof. N. Srinivasan

... 21-kDa monomers of around 80% sequence identity (den Dunnen et al., 1986; Hay et al., 1987). 0-Crystallin sequences differ from y-crystallins mainly in having extensions at theN- and C-termini. X-ray analysis of bovine py-crystallins has shown that they are built of 4Greek key motifs organizedas 2 s ...
Potent Neuropeptide Y Y, Receptor Antagonist, 1229U91: Blockade
Potent Neuropeptide Y Y, Receptor Antagonist, 1229U91: Blockade

... that regulate food intake. [‘251]PYY binding as well as [3H]NPY binding (data not shown) to the hypothalamus membranes showed a low affinity for the Y,-selective agonist [Leu3’,Pro34]NPY, indicating that Y, receptors are predominant in this region. This result is consistent with other reports (34-37 ...
Genes encoding putative effector proteins of the type III secretion
Genes encoding putative effector proteins of the type III secretion

... Several Gram-negative bacterial pathogens secrete virulence proteins via specialized type III secretion systems (Mecsas and Strauss, 1996). These secretion systems comprise a large number of proteins required to transfer specific effector proteins into eukaryotic host cells in a contact-dependent ma ...
ppt - Erice Crystallography 2006 IT Support
ppt - Erice Crystallography 2006 IT Support

... The following two computational methods can be used: • Normal Mode Analysis-guided flexible fitting (NMFF): molecule is modeled as an elastic network (“balls connected with springs”); only small amplitudes allowed. • Real-space refinement: provides multi-fragment docking, preserving structural integ ...
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... these hallmark characteristics (Heath, 1998). In addition to its role in developmental processes in plants, cell suicide plays an important role in the interactions of plants with pathogens, including bacteria, fungi, and viruses. One of the best studied of plant responses to pathogens is the hypers ...
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BiochemicalSociety A nnualSymposium No.77

... and ultimately plant morphology, is accomplished by the polarized targeting and localized release of secretorypathway-derived membrane and cell wall material at specific sites on the PM. Directional cell expansion in plants occurs through two distinct mechanisms: diffuse polar and tip growth [12], w ...
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... • IDL - produced in blood (remnant of VLDL) • LDL – produced in blood (remnant of IDL after TG digestion; high concentration of cholesterol; endocytosed by liver, other tissues (LDL receptor) • HDL – produced in liver, intestine; exchanges proteins and lipids with other lipoproteins; returns cholest ...
A1.3 SG - Mrs. Lee`s Science Class
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... • Ability to make food (autotrophs or heterotrophs or both) 2. What are prokaryotes & eukaryotes? • prokaryotes = organisms with NO nucleus in their cells • eukaryotes = organisms with nuclei (singular = nucleus) in their cells 3. What is a nucleus? • Nucleus = a dense area that contains nucleic aci ...
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Membrane nanodomains in plants: capturing form, function, and

... The plasma membrane is the interface between the cell and the external environment. Plasma membrane lipids provide scaffolds for proteins and protein complexes that are involved in cell to cell communication, signal transduction, immune responses, and transport of small molecules. In animals, fungi, ...
Section VI. Lipid metabolism overview:
Section VI. Lipid metabolism overview:

... • VLDL – produced from liver mainly from dietary carbohydrate; carries TG in blood • IDL - produced in blood (remnant of VLDL) • LDL – produced in blood (remnant of IDL after TG digestion; high concentration of cholesterol; endocytosed by liver, other tissues (LDL receptor) • HDL – produced in liver ...
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... Sedimentation is the tendency for molecules in solution to settle out of the fluid. This is due to their motion in response to the forces acting on them: gravity, ...
The Cerebellum, Basal Ganglia and Overall Motor
The Cerebellum, Basal Ganglia and Overall Motor

... cerebellum contributes to the rapid turn-on signals for agonist muscles and turn-off of antagonist muscles at beginning of a motion then it times the opposite sequence at the end of the intended motion direct motor pathway via corticospinal tract is enhanced by cerebellum by additional signals to th ...
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Micrasterias II - PROTISTEN.DE
Micrasterias II - PROTISTEN.DE

... Dictyosomes are usually too small and delicate to be identified by the optical microscope. Not so the species of Micrasterias with large cells (diameter 200 µm and larger). Such large and high-contrasted dictyosomes were already described in the 1960’s. However, the micrographs in the articles cite ...
AS Module 1 - heckgrammar.co.uk
AS Module 1 - heckgrammar.co.uk

... • Cohesion. Water molecules "stick together" due to their hydrogen bonds, so water has high cohesion. This explains why long columns of water can be sucked up tall trees by transpiration without breaking. It also explains surface tension, which allows small animals to walk on water. • Ionisation. Wh ...
TORC2 Signaling is Antagonized by Protein Phosphatase
TORC2 Signaling is Antagonized by Protein Phosphatase

... (Inoki et al. 2005; Wullschleger et al. 2006; Zoncu et al. 2011). The TOR kinase is inhibited by the complex of rapamycin and Fpr1, a peptidyl-prolyl cis-trans isomerase. The TOR kinase is conserved in eukaryotes. Unlike fungal species, which may possess two TOR kinases, higher eukaryotes such as h ...
Investigating the Dual Function of the Chloride Intracellular Ion
Investigating the Dual Function of the Chloride Intracellular Ion

... I certify that the work in this thesis has not previously been submitted for a degree nor has it been submitted as part of requirements for a degree except as fully acknowledged within the text. I also certify that the thesis has been written by me. Any help that I have received in my research work ...
Transport of substances in and out of the cell
Transport of substances in and out of the cell

... It is the dispersion of atoms, ions or molecules by random thermal motion (kinetic energy) until these particles are equally distributed in the available space. For example , if some particles concentrated in the left side of a vessel, they will collide with each others, some may spread to the right ...
Splice variants` role in mediating different disease states in
Splice variants` role in mediating different disease states in

... illumination of single nucleotide polymorphisms (SNP) of the calcium channel transporter, Cav 1.2 gene in the population through gene sequencing followed by bioinformatic analysis for alternative splice sites. This would be followed by a scan for alternative splice variants through colony polymerase ...
Susceptibility of phospholipids of Proteus mirabilis smooth and
Susceptibility of phospholipids of Proteus mirabilis smooth and

... leaflet and the outer leaflet contains protein and lipopolysaccharide molecules, whereas in the deep rough strain 20-40% of the phospholipids are present in the outer leaflet, forming phospholipid bilayer regions. If the phospholipase, like most outer membrane proteins, is located in the outer leafl ...
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Signal transduction



Signal transduction occurs when an extracellular signaling molecule activates a specific receptor located on the cell surface or inside the cell. In turn, this receptor triggers a biochemical chain of events inside the cell, creating a response. Depending on the cell, the response alters the cell's metabolism, shape, gene expression, or ability to divide. The signal can be amplified at any step. Thus, one signaling molecule can cause many responses.
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