Regulation of the cytoplasmic accumulation of 5
... chilled and the quantity of acid-labile (bound to exposed receptors) and acid-resistant (internal receptors) label was measured (Fig. 1). As the chase was lengthened there was an increase in the amount of 5-methyl[3H]tetrahydrofolic acid that was resistant to acid release and a corresponding decline ...
... chilled and the quantity of acid-labile (bound to exposed receptors) and acid-resistant (internal receptors) label was measured (Fig. 1). As the chase was lengthened there was an increase in the amount of 5-methyl[3H]tetrahydrofolic acid that was resistant to acid release and a corresponding decline ...
Arsenic Trioxide-Dependent Activation of Thousand-and
... two experiments. Right, as on the left, but using TAK1-specific siRNA. B, U937 cells were transfected with control siRNA or TAO2-specific siRNA, and cells were incubated in the absence or presence of As2O3 (2 M) for 30 min. Total cell lysates were resolved by SDS-PAGE and immunoblotted with an anti ...
... two experiments. Right, as on the left, but using TAK1-specific siRNA. B, U937 cells were transfected with control siRNA or TAO2-specific siRNA, and cells were incubated in the absence or presence of As2O3 (2 M) for 30 min. Total cell lysates were resolved by SDS-PAGE and immunoblotted with an anti ...
Passage 36
... Protein synthesis begins when the gene encoding a protein is activated. The gene’s sequence of nucleotides is transcribed into a molecule of messenger RNA (mRNA), which reproduces the information contained in that (5) sequence. Transported outside the nucleus to the cytoplasm, the mRNA is translated ...
... Protein synthesis begins when the gene encoding a protein is activated. The gene’s sequence of nucleotides is transcribed into a molecule of messenger RNA (mRNA), which reproduces the information contained in that (5) sequence. Transported outside the nucleus to the cytoplasm, the mRNA is translated ...
General introduction
... released from the presynaptic cell will elicit a postsynaptic response, which can be measured using electrophysiological techniques (Fatt and Katz, 1952). The binding of quanta of released neurotransmitter molecules to postsynaptic receptors elicits quantal responses in the postsynaptic cell. Change ...
... released from the presynaptic cell will elicit a postsynaptic response, which can be measured using electrophysiological techniques (Fatt and Katz, 1952). The binding of quanta of released neurotransmitter molecules to postsynaptic receptors elicits quantal responses in the postsynaptic cell. Change ...
Extracellular Matrix Molecules and Cell Adhesion Molecules Induce
... HA1004 on CG neurons grown on N-cadherin or L1 substrates. For both CAMs, HA1004 tended to increase the percentage of neurons with neurites, but not to the same extent as H7. These results suggest that inhibition, both of protein kinase C and of cyclic nucleotide-dependent kinases, can augment proce ...
... HA1004 on CG neurons grown on N-cadherin or L1 substrates. For both CAMs, HA1004 tended to increase the percentage of neurons with neurites, but not to the same extent as H7. These results suggest that inhibition, both of protein kinase C and of cyclic nucleotide-dependent kinases, can augment proce ...
Thalassiosira pseudonana The Transcriptome and Proteome of the Diatom Stress Response
... transcript. Coordination was also seen in the combined dataset for the 26 significantly downregulated proteins, with no transcripts showing opposing patterns (Table S5). Some transcripts were not significantly different between treatments, even though the corresponding protein was more or less abund ...
... transcript. Coordination was also seen in the combined dataset for the 26 significantly downregulated proteins, with no transcripts showing opposing patterns (Table S5). Some transcripts were not significantly different between treatments, even though the corresponding protein was more or less abund ...
BCL-6 Expression During B-Cell Activation
... distinct subgroup of DLCL that has a more favorable prognosis after chemotherapy,” although this correlation was not apparent in all studies.’ The BCL-6 protein has six Kriippel-like zinc fingers at its carboxy terminus and thus is presumably involved in transcriptional regulation.*4 In addition, BC ...
... distinct subgroup of DLCL that has a more favorable prognosis after chemotherapy,” although this correlation was not apparent in all studies.’ The BCL-6 protein has six Kriippel-like zinc fingers at its carboxy terminus and thus is presumably involved in transcriptional regulation.*4 In addition, BC ...
If I Were the Most Important Cell Organelle…. For nearly 1.5 billion
... If I Were the Most Important Cell Organelle…. For nearly 1.5 billion years, the nucleus has boasted its ability to direct cell activities. But now, all of the other cell organelles have called for an “organelle election.” The organelles have hired you to organize and run their individual election ca ...
... If I Were the Most Important Cell Organelle…. For nearly 1.5 billion years, the nucleus has boasted its ability to direct cell activities. But now, all of the other cell organelles have called for an “organelle election.” The organelles have hired you to organize and run their individual election ca ...
Membrane Trafficking During Plant Cytokinesis
... garrote. An alternative but not mutually exclusive idea is that the dynamin rings serve to recruit various binding partners, such as the lipid modification enzyme endophilin and other vesicle budding components that function in concert with dynamin to promote membrane scission (46). In addition to th ...
... garrote. An alternative but not mutually exclusive idea is that the dynamin rings serve to recruit various binding partners, such as the lipid modification enzyme endophilin and other vesicle budding components that function in concert with dynamin to promote membrane scission (46). In addition to th ...
Unit 3 Biology 7
... after you recover from a disease, your body no longer requires all the T and B cells that have been produced. Cells no longer useful to an organism die by apoptosis. Cell membranes have death receptors that receive the messages referred to above. When such a message is received, a cascade of events ...
... after you recover from a disease, your body no longer requires all the T and B cells that have been produced. Cells no longer useful to an organism die by apoptosis. Cell membranes have death receptors that receive the messages referred to above. When such a message is received, a cascade of events ...
Ch. 48 Lecture 48_Nervous_System
... • Graded potentials are changes in polarization where the magnitude of the change varies with the strength of the stimulus • These are not the nerve signals that travel along axons, but they do have an effect on the generation of nerve signals ...
... • Graded potentials are changes in polarization where the magnitude of the change varies with the strength of the stimulus • These are not the nerve signals that travel along axons, but they do have an effect on the generation of nerve signals ...
Isoforms of acetyl-CoA carboxylase
... important inhibitory phosphorylation site at Ser79 in rat ACC-1 is phosphorylated by AMP-activated protein kinase (AMP-PK). Additional sites at Ser-1200 and Ser-1215 may be phosphorylated by either AMP-PK or CAMP-dependent protein kinase (PKA), and although these latter two sites are phosphorylated ...
... important inhibitory phosphorylation site at Ser79 in rat ACC-1 is phosphorylated by AMP-activated protein kinase (AMP-PK). Additional sites at Ser-1200 and Ser-1215 may be phosphorylated by either AMP-PK or CAMP-dependent protein kinase (PKA), and although these latter two sites are phosphorylated ...
Cell Cycle Regulation of the Activity and Subcellular Localization of
... The activity of wild-type polo kinase was measured during the rapid cell cycles of syncytial Drosophila embryos and reported to be maximal during late anaphase and early telophase (Fenton and Glover, 1993). Interestingly, recent studies have revealed that the CDC5 gene of Saccharomyces cerevisiae en ...
... The activity of wild-type polo kinase was measured during the rapid cell cycles of syncytial Drosophila embryos and reported to be maximal during late anaphase and early telophase (Fenton and Glover, 1993). Interestingly, recent studies have revealed that the CDC5 gene of Saccharomyces cerevisiae en ...
Learning Guide: Origins of Life
... 2. In the absence of oxygen, fermentation occurs. Explain the primary purpose of this process. 3. Identify the source of the electrons that travel down the electron transport chain. Explain why oxygen is the final electron acceptor in aerobic cellular respiration. 4. Create a graphic organizer that ...
... 2. In the absence of oxygen, fermentation occurs. Explain the primary purpose of this process. 3. Identify the source of the electrons that travel down the electron transport chain. Explain why oxygen is the final electron acceptor in aerobic cellular respiration. 4. Create a graphic organizer that ...
Understanding the Human Sensory Conduction of Smell
... electrical activity in 1998 [32]. After Buck left Axel’s laboratory, ...
... electrical activity in 1998 [32]. After Buck left Axel’s laboratory, ...
Signaling from synapse to nucleus: the logic behind the mechanisms Karl Deisseroth
... what are the crucial and specific signal initiators? Second, what are the nuclear translocators, and why are they selected for the task? Third and finally, what is the basis for stimulus specificity and reliable information transfer? By focusing on the pathways triggered by an intracellular Ca2þ ris ...
... what are the crucial and specific signal initiators? Second, what are the nuclear translocators, and why are they selected for the task? Third and finally, what is the basis for stimulus specificity and reliable information transfer? By focusing on the pathways triggered by an intracellular Ca2þ ris ...
1 a dictyostelium mutant with reduced lysozyme levels compensates
... particles. The lysosome is the most potent degradative organelle within the eukaryotic cell. It contains hydrolytic enzymes that fulfill essential functions. In humans, many mutations affecting its constituents lead to the diseased state, often with dramatic consequences. Mutations of this sort fall ...
... particles. The lysosome is the most potent degradative organelle within the eukaryotic cell. It contains hydrolytic enzymes that fulfill essential functions. In humans, many mutations affecting its constituents lead to the diseased state, often with dramatic consequences. Mutations of this sort fall ...
Chapter 7 Membrane Structure and Function
... 19) An animal cell lacking oligosaccharides on the external surface of its plasma membrane would likely be impaired in which function? A) transporting ions against an electrochemical gradient B) cell-cell recognition C) maintaining fluidity of the phospholipid bilayer D) attaching to the cytoskeleto ...
... 19) An animal cell lacking oligosaccharides on the external surface of its plasma membrane would likely be impaired in which function? A) transporting ions against an electrochemical gradient B) cell-cell recognition C) maintaining fluidity of the phospholipid bilayer D) attaching to the cytoskeleto ...
Lecture-Intro to metabolism - Creighton Chemistry Webserver
... Example: rate of glycolysis increases 100-fold in working muscle vs. resting muscle Various pathways must be integrated to work together ...
... Example: rate of glycolysis increases 100-fold in working muscle vs. resting muscle Various pathways must be integrated to work together ...
Amyotrophic Lateral Sclerosis SOD1
... by Rac1 is controlled through a redox-dependent interaction with the ubiquitous enzyme Cu+/Zn+ superoxide dismutase (SOD1), which is found mutated in ALS patients. When SOD1 is bound to Rac1 under reducing conditions, GTP hydrolysis is inhibited; in oxidizing conditions, SOD1 dissociates from Rac1, ...
... by Rac1 is controlled through a redox-dependent interaction with the ubiquitous enzyme Cu+/Zn+ superoxide dismutase (SOD1), which is found mutated in ALS patients. When SOD1 is bound to Rac1 under reducing conditions, GTP hydrolysis is inhibited; in oxidizing conditions, SOD1 dissociates from Rac1, ...
Biology 181: Study Guide
... 4. Organisms live at the expense of free energy 5. ATP powers cellular work: it couples exergonic to endergonic reactions 6. Enzymes are protein catalysts: they speed up metabolic processes a. lower energy barriers b. substrate specific c. active site 7. The chemical and physical environment affect ...
... 4. Organisms live at the expense of free energy 5. ATP powers cellular work: it couples exergonic to endergonic reactions 6. Enzymes are protein catalysts: they speed up metabolic processes a. lower energy barriers b. substrate specific c. active site 7. The chemical and physical environment affect ...
Phosphorylation of initiation factor2 is required for
... of the exchange of eIF2-bound GDP for GTP. As GTP binding to eIF2 is a prerequisite to Met-tRNAi binding, phosphorylation of eIF2a effectively inhibits eIF2 recycling and consequently inhibits additional translation initiation steps (reviewed in [4]). The control mechanisms that govern the rate of g ...
... of the exchange of eIF2-bound GDP for GTP. As GTP binding to eIF2 is a prerequisite to Met-tRNAi binding, phosphorylation of eIF2a effectively inhibits eIF2 recycling and consequently inhibits additional translation initiation steps (reviewed in [4]). The control mechanisms that govern the rate of g ...
Higher Human Biology Resource Guide - Glow Blogs
... code for proteins specific to a particular function. This is also known as selective gene expression. Learners should develop an understanding that stem cells are unspecialised cells that have the potential to reproduce by mitosis while remaining undifferentiated and can differentiate into any speci ...
... code for proteins specific to a particular function. This is also known as selective gene expression. Learners should develop an understanding that stem cells are unspecialised cells that have the potential to reproduce by mitosis while remaining undifferentiated and can differentiate into any speci ...
Signal transduction
Signal transduction occurs when an extracellular signaling molecule activates a specific receptor located on the cell surface or inside the cell. In turn, this receptor triggers a biochemical chain of events inside the cell, creating a response. Depending on the cell, the response alters the cell's metabolism, shape, gene expression, or ability to divide. The signal can be amplified at any step. Thus, one signaling molecule can cause many responses.