Distribution of Furamidine Analogues in Tumor Cells: Targeting of
... important class of antimicrobial and antiparasitic agents. This diphenylfuran derivative has shown potent activities against several pathogen microorganisms such as Cryptosporidium parvum (4), Pneumocystis carinii (5), and Trypanosoma sp (6, 7). An amidoxime prodrug of furamidine (8) is currently un ...
... important class of antimicrobial and antiparasitic agents. This diphenylfuran derivative has shown potent activities against several pathogen microorganisms such as Cryptosporidium parvum (4), Pneumocystis carinii (5), and Trypanosoma sp (6, 7). An amidoxime prodrug of furamidine (8) is currently un ...
Essential embryonic roles of the CKI-1 cyclin
... cycle arrest, morphogenesis and differentiation, and suppression of programmed cell death. The vertebrate Cip/Kip CKIs have been shown to directly inhibit the activity of cyclin/cyclin-dependent kinase (cdk) complexes that control G1/S progression, leading to G1 arrest (Sherr and Roberts, 1995). The ...
... cycle arrest, morphogenesis and differentiation, and suppression of programmed cell death. The vertebrate Cip/Kip CKIs have been shown to directly inhibit the activity of cyclin/cyclin-dependent kinase (cdk) complexes that control G1/S progression, leading to G1 arrest (Sherr and Roberts, 1995). The ...
(From tl~ Laboratories of The Rockefeller Institute far Medical
... system so that this will be discussed first and in more detail. Table I shows that at a mustard concentration of 0.8 X 10-8 ~ the phage formation is still 50 per cent or more of the untreated control but the number of organisms which can multiply in a veal-peptone infusion has decreased from 1 X l0 ...
... system so that this will be discussed first and in more detail. Table I shows that at a mustard concentration of 0.8 X 10-8 ~ the phage formation is still 50 per cent or more of the untreated control but the number of organisms which can multiply in a veal-peptone infusion has decreased from 1 X l0 ...
Studies of vacuolar trafficking pathways regulated by RAB5 and
... daughter cells in mutant roots further divided periclinally (Figure 4). These results indicate that VPS9a is required to repress middle cortex formation at the premature stage in root development. It has been shown that middle cortex formation is under regulation of a plant hormone, gibberellin (Paq ...
... daughter cells in mutant roots further divided periclinally (Figure 4). These results indicate that VPS9a is required to repress middle cortex formation at the premature stage in root development. It has been shown that middle cortex formation is under regulation of a plant hormone, gibberellin (Paq ...
Drosophila immune cell migration and adhesion during embryonic
... over-expressed in areas the plasmatocytes normally cross, it triggers plasmatocyte accumulation, which could be caused by attraction or adhesion [13,16,25]. Pvfs have not been used to redirect plasmatocytes to a new area, as was demonstrated with another migratory cell type, border cells [46]. Expre ...
... over-expressed in areas the plasmatocytes normally cross, it triggers plasmatocyte accumulation, which could be caused by attraction or adhesion [13,16,25]. Pvfs have not been used to redirect plasmatocytes to a new area, as was demonstrated with another migratory cell type, border cells [46]. Expre ...
Ep iclo ne A H G Po ly A H G A nti-Ig G
... antiglobulin tests. The polyspecific Anti-Human Globulin reagent contains antibodies to both immunoglobulins (mainly IgG) and complement components (C3d) and is designed as the primary reagent for antibody detection, compatibility tests and investigation of auto-immune haemolytic anaemias. The first ...
... antiglobulin tests. The polyspecific Anti-Human Globulin reagent contains antibodies to both immunoglobulins (mainly IgG) and complement components (C3d) and is designed as the primary reagent for antibody detection, compatibility tests and investigation of auto-immune haemolytic anaemias. The first ...
Regulation of Proto-Oncogene and Tumor Necrosis
... actin mRNA levels supported a specific decline in c-myc and c-myb expression. However, recent studies have shown that c-myc protein levels are maintained in the presence of declines in c-myc transcripts during differentiation of certain cell lines." These results question the significance of the tra ...
... actin mRNA levels supported a specific decline in c-myc and c-myb expression. However, recent studies have shown that c-myc protein levels are maintained in the presence of declines in c-myc transcripts during differentiation of certain cell lines." These results question the significance of the tra ...
Lineage Commitment During T cell Development
... Notch signaling is critical for the induction of multiple transcription factors Yui and Rothernberg, NRI, 2014 ...
... Notch signaling is critical for the induction of multiple transcription factors Yui and Rothernberg, NRI, 2014 ...
Cells: The Basic Units of Life
... barrier. It separates the cell’s contents from its environment. The cell membrane also controls materials going into and out of the cell. Inside the cell is a fluid. This fluid and almost all of its contents are called the cytoplasm (SIET oh PLAZ uhm). ...
... barrier. It separates the cell’s contents from its environment. The cell membrane also controls materials going into and out of the cell. Inside the cell is a fluid. This fluid and almost all of its contents are called the cytoplasm (SIET oh PLAZ uhm). ...
Evidence for Gal3p`s Cytoplasmic Location
... added at 2%, and the cells were incubated for two additional hours. Cell fractionation and nuclei enrichment were carried out using two independent protocols, one based on a sucrose gradient method (24, 48) and the other based on a Ficoll gradient method (2, 16). Both procedures gave similar results ...
... added at 2%, and the cells were incubated for two additional hours. Cell fractionation and nuclei enrichment were carried out using two independent protocols, one based on a sucrose gradient method (24, 48) and the other based on a Ficoll gradient method (2, 16). Both procedures gave similar results ...
Lethality of radioisotopes in early mouse embryos
... label. This was achieved by the addition of non-radioactive methionine to the culture medium. Results of such an experiment are shown in Table 1. It is clear that survival can indeed be increased by lowering the specific activity to 002 Ci/mmol. Furthermore, it could be shown, in separate experiment ...
... label. This was achieved by the addition of non-radioactive methionine to the culture medium. Results of such an experiment are shown in Table 1. It is clear that survival can indeed be increased by lowering the specific activity to 002 Ci/mmol. Furthermore, it could be shown, in separate experiment ...
The nuclear membrane in multidrug resistance
... All cell lines were cultured in Dulbecco’s Modified Eagle’s Medium supplemented with 2 mmol/L L-glutamine, 10% fetal calf serum and 100 mg/mL of both penicillin/ streptomycin solution (Sigma Chem Co., Poole, UK). Cells were passaged using trypsinEDTA (Sigma) when 85% confluent. Cultures were maintai ...
... All cell lines were cultured in Dulbecco’s Modified Eagle’s Medium supplemented with 2 mmol/L L-glutamine, 10% fetal calf serum and 100 mg/mL of both penicillin/ streptomycin solution (Sigma Chem Co., Poole, UK). Cells were passaged using trypsinEDTA (Sigma) when 85% confluent. Cultures were maintai ...
Sponges and Cnidarians
... persisted on Earth for more than half a billion years. Lacking a true digestive system, sponges depend on the intracellular digestive processes of their choanocytes for their energy intake. The limit of this type of digestion is that food particles must be smaller than individual cells. Gas exchange ...
... persisted on Earth for more than half a billion years. Lacking a true digestive system, sponges depend on the intracellular digestive processes of their choanocytes for their energy intake. The limit of this type of digestion is that food particles must be smaller than individual cells. Gas exchange ...
Cyclin Dependent Kinases and Cell Cycle Control
... of mitotic onset and proposed that wee1 and cdc2 acted together in a regulatory network controlling the onset of mitosis. Next it was shown that cdc2 had a role controlling the onset of S-phase. This came about as a consequence of a survey of cdc mutants to look for those which blocked in G1 phase p ...
... of mitotic onset and proposed that wee1 and cdc2 acted together in a regulatory network controlling the onset of mitosis. Next it was shown that cdc2 had a role controlling the onset of S-phase. This came about as a consequence of a survey of cdc mutants to look for those which blocked in G1 phase p ...
The Polymeric Immunoglobulin Receptor Accumulates in
... (Mostov et al., 1984) or Asp~4 mutant (Casanova et al., 1990) forms of the rabbit pIgR was subeloned into the cytomegalovirus-based expression vector, pCB6 (Brewer and Roth, 1991). eDNA encoding the human LDL-R (Davis et al., 1986) was subeloned into pCB6 as described (Green et al., 1994). G418-resi ...
... (Mostov et al., 1984) or Asp~4 mutant (Casanova et al., 1990) forms of the rabbit pIgR was subeloned into the cytomegalovirus-based expression vector, pCB6 (Brewer and Roth, 1991). eDNA encoding the human LDL-R (Davis et al., 1986) was subeloned into pCB6 as described (Green et al., 1994). G418-resi ...
End of Year Study Guide
... Explain the meaning of heredity. S5P1: Students will verify that an object is the sum of its parts a. Demonstrate that the mass of an object is equal to the sum of its parts by manipulating and measuring different objects made of various parts. *Understand how to solve problems such as: Carole has t ...
... Explain the meaning of heredity. S5P1: Students will verify that an object is the sum of its parts a. Demonstrate that the mass of an object is equal to the sum of its parts by manipulating and measuring different objects made of various parts. *Understand how to solve problems such as: Carole has t ...
Identification of a Platelet-aggregating Factor of
... thrombin (data not shown). Furthermore, this platelet aggre gation was not induced by ADP-efflux from the tumor cells, since the platelet aggregation was always measured in PRPcontaining apyrase (0.5 units/ml), an ADP degrading enzyme. These data indicate that the platelet aggregation induced by NL- ...
... thrombin (data not shown). Furthermore, this platelet aggre gation was not induced by ADP-efflux from the tumor cells, since the platelet aggregation was always measured in PRPcontaining apyrase (0.5 units/ml), an ADP degrading enzyme. These data indicate that the platelet aggregation induced by NL- ...
Lecture 10: The Extracellular matrix
... 30. Proteoglycans have numerous functions and found in every tissue of the body mainly in ECM or ‘ground substance’ where they are associated with each other and also with the other major structural components of the matrix, collagen and elastin. These interactions are important in determining the s ...
... 30. Proteoglycans have numerous functions and found in every tissue of the body mainly in ECM or ‘ground substance’ where they are associated with each other and also with the other major structural components of the matrix, collagen and elastin. These interactions are important in determining the s ...
Cell distribution and regenerative activity following meniscus
... term, long-term follow-up indicates that meniscal removal provides an increased risk of osteoarthritis [3, 4]. While meniscal repair is growing in popularity, its role is relatively limited given the inherent low vascularity of the inner zones of the meniscus [5, 6]. Furthermore, repair in the outer ...
... term, long-term follow-up indicates that meniscal removal provides an increased risk of osteoarthritis [3, 4]. While meniscal repair is growing in popularity, its role is relatively limited given the inherent low vascularity of the inner zones of the meniscus [5, 6]. Furthermore, repair in the outer ...
7.2 powerpoint
... In many cells, the smooth ER contains collections of enzymes that perform specialized tasks, including the synthesis of membrane lipids and the detoxification of drugs. ...
... In many cells, the smooth ER contains collections of enzymes that perform specialized tasks, including the synthesis of membrane lipids and the detoxification of drugs. ...
Untitled - University of Guelph
... conveys the fact that, during development, one region of a cell grows differently from another, but it raises the question of how preferences for localized growth can be created within a cell. Furthermore, what molecular hierarchy might operate between cellular components for differential growth to ...
... conveys the fact that, during development, one region of a cell grows differently from another, but it raises the question of how preferences for localized growth can be created within a cell. Furthermore, what molecular hierarchy might operate between cellular components for differential growth to ...
Approaches for Monitoring Nuclear Translation
... 3.2.2. A Basic “Translation Mixture” for “Run-On” Translation The translation reaction involves incubating nuclei or permeabilized cells with the appropriate labeled precursor, the other amino acids, ATP, GTP, and an energy-regenerating system. Our basic translation mixture contains PB*BSA (which co ...
... 3.2.2. A Basic “Translation Mixture” for “Run-On” Translation The translation reaction involves incubating nuclei or permeabilized cells with the appropriate labeled precursor, the other amino acids, ATP, GTP, and an energy-regenerating system. Our basic translation mixture contains PB*BSA (which co ...
Bio 226: Cell and Molecular Biology
... Decide which way to divide & which way to elongate • Periclinal = perpendicular to surface: get longer • Anticlinal = parallel to surface: add more layers Now must decide which way to elongate: which walls to stretch ...
... Decide which way to divide & which way to elongate • Periclinal = perpendicular to surface: get longer • Anticlinal = parallel to surface: add more layers Now must decide which way to elongate: which walls to stretch ...
tissues - Linn-Benton Community College
... (plasma). Function: Transport of respiratory gases, nutrients, wastes, and other substances. ...
... (plasma). Function: Transport of respiratory gases, nutrients, wastes, and other substances. ...
Summary/Reflection of Dan Freedman`s article, Science Education
... From here, the muscular left ventricle pumps the blood into the large artery, the aorta, through the aortic semilunar valve, and throughout the body. 1) Similar to the valves on the right side of the heart, the left AV valve prevents movement of blood into the atrium, and the semilunar valve prevent ...
... From here, the muscular left ventricle pumps the blood into the large artery, the aorta, through the aortic semilunar valve, and throughout the body. 1) Similar to the valves on the right side of the heart, the left AV valve prevents movement of blood into the atrium, and the semilunar valve prevent ...
Cell culture
Cell culture is the process by which cells are grown under controlled conditions, generally outside of their natural environment. In practice, the term ""cell culture"" now refers to the culturing of cells derived from multicellular eukaryotes, especially animal cells, in contrast with other types of culture that also grow cells, such as plant tissue culture, fungal culture, and microbiological culture (of microbes). The historical development and methods of cell culture are closely interrelated to those of tissue culture and organ culture. Viral culture is also related, with cells as hosts for the viruses. The laboratory technique of maintaining live cell lines (a population of cells descended from a single cell and containing the same genetic makeup) separated from their original tissue source became more robust in the middle 20th century.