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Exercise 14: Bacterial Endospores
Exercise 14: Bacterial Endospores

... • Endospores are ultimately protection for the bacterial genome • Spores form within the cell and contain a full copy of the bacterium’s genome • Endospores are not a form of reproduction, because only one new cell germinates from each spore • Spores can be variable in size and location within the c ...
Embryonic electronics - The Department of Computer Science
Embryonic electronics - The Department of Computer Science

Beyond ergosterol
Beyond ergosterol

... shows that wild-type C. albicans cells are more capable than a filamentation-defective mutant (efg1Δ/cph1Δ) in blocking phagosomal maturation and acidification.32 Consistent with these findings, we observe that vma7-/- mutants of C. albicans fail to colonize Caco-2 epithelial models in culture and a ...
GYP5 - Genetics
GYP5 - Genetics

... and are dynamic in composition (for review see PRUYNE and BRETSCHER 2000, MUNN 2001). Actin patches are thought to be sites of endocytosis (for review see ENGQVIST-GOLDSTEIN and DRUBIN 2003); however the mechanism of this is only beginning to be understood (KAKSONEN et al. 2003). ...
Dynamics of the Plant Nuclear Envelope and
Dynamics of the Plant Nuclear Envelope and

... Joanna Boruc, Xiao Zhou, and Iris Meier* Department of Molecular Genetics, The Ohio State University, Columbus, Ohio 43210 The nucleus is the most prominent compartment of any eukaryotic cell and home to its genetic information. The nucleoplasm is surrounded by a double membrane system, the nuclear ...
Improving pancreatic cancer drug discovery by leveraging genomics
Improving pancreatic cancer drug discovery by leveraging genomics

... not. Overall, it was observed that cell lines have more CNVs than tumors, representing an important limitation of cell lines as models for tumors. ...
Plant Structure And Growth
Plant Structure And Growth

... Auxin stimulates growth Auxin block on right causes cells to elongate and the plant bends left Auxin block on left causes cells to elongate the the plant bends right ...
Ex Vivo Expansion of Oral Mucosal Epithelial Stem Cells on Freeze
Ex Vivo Expansion of Oral Mucosal Epithelial Stem Cells on Freeze

...  We have cultured oral mucosal epithelial cells (ECs) from biopsy-derived oral mucosal tissues on sterilized FD-AM. The use of the explant culture technique circumvented the dependence on feeder cells, which eliminates the risk of xenogeneic contamination.  We were able to observe nuclear expressi ...
a fresh approach to understanding human development using single
a fresh approach to understanding human development using single

... developmental biology. Over the years, we have learned much with regard to the molecular events that instruct cell lineage, the specific growth factors that are required, and the morphological aspects that drive organ development. Most of this knowledge has been gained from studying non-human verteb ...
Sticking the Landing: Probing the Roles of LORELEI
Sticking the Landing: Probing the Roles of LORELEI

... FERONIA (FER), a receptor-like kinase that it chaperones from the endoplasmic reticulum (Li et al., 2015), although the precise mechanisms are unclear. LRE might also play a separate role at the synergid surface. Through clever structure-function analysis of LRE in Arabidopsis thaliana, Liu et al. ( ...
video slide
video slide

... (b) Dinoflagellates. In unicellular protists called dinoflagellates, the nuclear envelope remains intact during cell division, and the chromosomes attach to the nuclear envelope. Microtubules pass through the nucleus inside cytoplasmic tunnels, reinforcing the spatial orientation of the nucleus, whi ...
Protein transport across the endoplasmic reticulum membrane
Protein transport across the endoplasmic reticulum membrane

... Saccharomyces cerevisiae and E. coli and have only moderate translocation defects [32–34]. However, the crystal structures of these mutants show that new plugs are formed from neighboring polypeptide segments [34]. The new plugs still seal the closed channel, but they have lost many interactions tha ...
Rab3GEP Is the Non-redundant Guanine Nucleotide
Rab3GEP Is the Non-redundant Guanine Nucleotide

Commentary in EMBO Journal
Commentary in EMBO Journal

the proposal
the proposal

... Anna Tramontano. The Ten Most Wanted Solutions in Protein Bioinformatics. Anna ...
The Inhibitory Effect of Compound 48/80 on the Formation of Giant
The Inhibitory Effect of Compound 48/80 on the Formation of Giant

... The degree of activation of the lysosomes was studied 6½ to 7 hr after addition of the respective substances by application of euchrysine (Allison, 1967 ). Only compound 48/8o and heparin were able to block giant cell formation. Both substances also inhibited the penetration of the virus (Table 2). ...
Kidney Handling of Acids/Bases, and Renal Tubular Acidosis
Kidney Handling of Acids/Bases, and Renal Tubular Acidosis

... (and generates HCO3- for the ECF) (Image credit: Dr. McLaughlin May 4th 2012 lecture) ...
Functional Roles Of Lipids In membranes - IJS
Functional Roles Of Lipids In membranes - IJS

... Lipids are defined as those biological molecules readily soluble in organic solvents such as chloroform, ether, or toluene. However, some very hydrophobic proteins such as the F0 subunits of ATP synthase are soluble in chloroform, and lipids with large hydrophilic domains such as lipopolysaccharide ...
In Search of Mitochondrial Mechanisms: Interfield
In Search of Mitochondrial Mechanisms: Interfield

... hydroxyl, carboxyl, and amino groups could link to a carbon backbone,5 and had succeeded in localizing respiration as an intracellular process.6 However, there was disagreement about the extent to which such processes could be understood in terms of ordinary chemical reactions stimulated by catalyst ...
Laminin presentation Tuesday
Laminin presentation Tuesday

... Some components can be purified Isolated molecules lack the molecular interactions that constitute basement membranes ...
Proteomics identification and annotation of proteins of a cell line of
Proteomics identification and annotation of proteins of a cell line of

The cytoplasm of living cells: a functional mixture of thousands of
The cytoplasm of living cells: a functional mixture of thousands of

... the millions of interactions that occur in the cytoplasm. In the remainder of this introduction we will consider some of the basic questions we can ask about the cytoplasm. What is in it? A concentrated solution of macromolecules, predominantly protein, but also RNA and in the case of prokaryotes on ...
chl - Govt College Aron
chl - Govt College Aron

... Chromoplasts : (chromo=color) plastids containing pigments other than chlorophyll; responsible for the orange and yellow color of fruits, flowers and autumn leaves. Chloroplasts: (Chloro= green) Chlorophyll-containing plastids which are the sites of photosynthesis •Found in eukaryotic algae, leave ...
The dynamics of plant plasma membrane proteins
The dynamics of plant plasma membrane proteins

... plasma membrane proteins in plants experienced a great leap forward (Krecek et al., 2009; Grunewald and Friml, 2010; Löfke et al., 2013a). Auxin, as one of the ‘classical’ plant hormones, is central to the control of cell proliferation and morphogenesis and its activity has been linked to a wide var ...
Lecture 12 Electromyography
Lecture 12 Electromyography

... 1.) Train of AP sweep into muscle membrane (sarcolemma) 2.) Travel INTO muscle cells through invaginations (T-tubules) 3.) AP trigger release of Ca2+ ions from sarcoplasmic reticulum into muscle cytoplasm 4.) Ca ions start the cascade of filament sliding *this is a EXTREMELY brief synopsis of the ex ...
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Endomembrane system

The endomembrane system is composed of the different membranes that are suspended in the cytoplasm within a eukaryotic cell. These membranes divide the cell into functional and structural compartments, or organelles. In eukaryotes the organelles of the endomembrane system include: the nuclear membrane, the endoplasmic reticulum, the Golgi apparatus, lysosomes, vesicles, endosomes and the cell membrane. The system is defined more accurately as the set of membranes that form a single functional and developmental unit, either being connected directly, or exchanging material through vesicle transport. Importantly, the endomembrane system does not include the membranes of mitochondria or chloroplasts.The nuclear membrane contains two lipid bilayers that encompass the contents of the nucleus. The endoplasmic reticulum (ER) is a synthesis and transport organelle that branches into the cytoplasm in plant and animal cells. The Golgi apparatus is a series of multiple compartments where molecules are packaged for delivery to other cell components or for secretion from the cell. Vacuoles, which are found in both plant and animal cells (though much bigger in plant cells), are responsible for maintaining the shape and structure of the cell as well as storing waste products. A vesicle is a relatively small, membrane-enclosed sac that stores or transports substances. The cell membrane, is a protective barrier that regulates what enters and leaves the cell. There is also an organelle known as the Spitzenkörper that is only found in fungi, and is connected with hyphal tip growth.In prokaryotes endomembranes are rare, although in many photosynthetic bacteria the plasma membrane is highly folded and most of the cell cytoplasm is filled with layers of light-gathering membrane. These light-gathering membranes may even form enclosed structures called chlorosomes in green sulfur bacteria.The organelles of the endomembrane system are related through direct contact or by the transfer of membrane segments as vesicles. Despite these relationships, the various membranes are not identical in structure and function. The thickness, molecular composition, and metabolic behavior of a membrane are not fixed, they may be modified several times during the membrane's life. One unifying characteristic the membranes share is a lipid bilayer, with proteins attached to either side or traversing them.
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