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BioScience®
BioScience®

... more fodder to demolish the anti-intellectual arguments about the complexity of cilia being a hindrance to their evolution by natural selection. There are a wide range of microtubule-containing cell surface extensions found among protists, and they perform multiple functions, such as organelle trans ...
Mitochondrial Transfer Is Transplantation, Not Genetic Engineering
Mitochondrial Transfer Is Transplantation, Not Genetic Engineering

... From an ethical perspective, mitochondrial transfer is most accurately described as a form of transplantation, or "micro-organ" transplantation. The human body is made up of microscopic building blocks called cells. There are around 100 trillion of them in the human body. There are around 200 differ ...
Phosphatidylserine, a death knell
Phosphatidylserine, a death knell

... years, however, a growing body of evidence has suggested that physical and chemical properties of the bilayer itself, such as the thickness of the hydrophobic core1 or local lateral domains of specialized lipid composition2 ± 4 may play significant roles in the assembly and organization of cellular ...
Populus endobetamannanase PtrMAN6 plays a role in coordinating
Populus endobetamannanase PtrMAN6 plays a role in coordinating

... structure and stockpile the majority of photosynthesisfixed carbon and solar energy. CWs can be generally classified into the primary cell wall (PCW) and secondary cell wall (SCW), which are formed through different processes and are regulated via different pathways. The PCW begins to form along wit ...
Endoplasmic Reticulum Export Sites and Golgi Bodies Behave as
Endoplasmic Reticulum Export Sites and Golgi Bodies Behave as

... contrast, Sec12p is uniformly distributed along the ER network and does not accumulate in these structures, consistent with the fact that Sec12p does not become part of a COPII vesicle. We propose that punctate accumulation of Sar1p represents ER export sites (ERES). The sites may represent a combin ...
The Tobacco Homolog of Mammalian Calreticulin
The Tobacco Homolog of Mammalian Calreticulin

... products to their final locations, causes a constant leakage of ER resident proteins to more dista1 compartments of the endomembrane system. The eukaryotic cell has developed efficient means to limit this leakage to a minimum to maintain adequate levels of intrinsic ER components at the site where t ...
Involvement of the Vacuoles of the Endodermis in
Involvement of the Vacuoles of the Endodermis in

... gravity with similar kinetics to wild-type plants, although the parental zig-1 plants showed little response even after 24 hr. In addition, their lateral stems, which in the parental zig-1 mutant curl downward, grew upward (Figure 2B). Interestingly, however, pSCR::ZIG could not complement the morph ...
Skin and bones: the bacterial cytoskeleton, cell wall, and cell
Skin and bones: the bacterial cytoskeleton, cell wall, and cell

... it from the turgor pressure exerted by the cytoplasm. The wall restrains the turgor pressure to avoid swelling and lysis, and the turgor pressure, in turn, is regarded as one of the primary forces that stretches the wall, favoring bond breaking and new PG insertion during cell growth (Koch, 1985; Ha ...
Intercellular adhesion, signalling and the cytoskeleton
Intercellular adhesion, signalling and the cytoskeleton

... in Madin Darby Canine Kidney (MDCK) epithelial cells18. At the initial stages of calcium-induced intercellular adhesion, E-cadherin, βcatenin and α-catenin organize into distinct aggregates, referred to as ‘puncta’18,19. These cadherin–catenin complexes are linked to the cytoskeleton through thin bu ...
Characterization and Expression of Monosaccharide Transporters
Characterization and Expression of Monosaccharide Transporters

... bidopsis (STP1), and humans (GLUT1), with a similar position of twelve hydrophobic transmembrane domains separated by a central long hydrophilic region (Fig. 1). Henderson et al. (1992) and Pao et al. (1998) proposed conserved motifs on sugar transport proteins including those having the transport a ...
Review Handout
Review Handout

... Cells are in close contact with one another; there is little intercellular matrix Cells form: Sheets that line body surfaces (internal and external) Glands derived from the surface sheets Cells are often linked by many types of membrane junctions Functions include: Protect against mechanical abrasio ...
Examples of Ciliophorans
Examples of Ciliophorans

... Significance of Ciliates ...
MS Cell Division, Reproduction, and Protein Synthesis
MS Cell Division, Reproduction, and Protein Synthesis

... Before a eukaryotic cell divides, the nucleus and other organelles must be copied. Only then will each daughter cell have all the needed structures. 1. The first step in eukaryotic cell division, as it is in prokaryotic cell division, is DNA replication. As you can see in Figure 1.5, each chromosome ...
IRIC NEXT GENERATION INTERNSHIP AWARDS
IRIC NEXT GENERATION INTERNSHIP AWARDS

... interphase. Although this series of cell shape transformations were originally described more than 130 years ago, the underlying mechanisms remain poorly understood. We have established that Ezrin, Radixin, Moesin (ERM) proteins, control cell morphogenesis during mitosis. During mitosis Drosophila M ...


... characterized vesicle morphology and protein composition by a combination of techniques including electron microscopy, proteomics, enzymatic activity, and serological reactivity. Secretory vesicles in C. neoformans appear to be correlated with exosome-like compartments derived from multivesicular bo ...
PHOSPHATE TRANSPORTER TRAFFIC FACILITATOR1 Is a Plant
PHOSPHATE TRANSPORTER TRAFFIC FACILITATOR1 Is a Plant

... not mislocalized, and the secretion of Pi starvation–induced RNases was not affected in the mutant. PHF1 encodes a plantspecific protein structurally related to the SEC12 proteins of the early secretory pathway. However, PHF1 lacks most of the conserved residues in SEC12 proteins essential as guanin ...
the fine structure of the mid-body of the rat
the fine structure of the mid-body of the rat

... usually seen running from the bridge into the adjoining cytoplasm of the daughter cells (Figs. 5 to 7). The final process of the rupture of the bridge is not conveniently studied in thin sections because of the difficulty of distinguishing truly parted bridges from those sectioned obliquely. We have ...
Cytoplasmatic Bacterial Membrane Responses to Environmental
Cytoplasmatic Bacterial Membrane Responses to Environmental

... (in DB21MT-2) and 22:6 (in both) polyunsaturated fatty acids. The presence of polyunsaturated fatty acids is uncommon in most bacteria but present in a higher proportion of isolates from low temperature and deep-sea environments [42]. Polyunsaturated fatty acids are probably produced by deep-sea bac ...


... The mechanisms of secretion of macromolecules by fungal cells have not been well elucidated. Fungal cells are encased in a rigid, pore-containing cell wall consisting of polysaccharides, ...
Information, Noise and Communication: Thresholds as Controlling
Information, Noise and Communication: Thresholds as Controlling

... between individual cells from the same culture. Lango and Hasty (2006) list 25 papers that have used this technology. The ultimate has been the imaging of the synthesis of individual protein and mRNA molecules. The most common detection of noise has been to compare copy numbers of both specific mRNA ...
Force development by the contractile vacuole
Force development by the contractile vacuole

... digestive vacuoles and mitochondria were also enclosed in the droplet. This isolated in vitro CV showed rounding-slackening cycles at regular intervals for more than 30 minutes when the preparation was kept at room temperature (24-27°C). Estimation of tension at the surface of an in vitro CV from th ...
Smart thermoresponsive coatings and surfaces for tissue
Smart thermoresponsive coatings and surfaces for tissue

... perspective, the disruption of the newly formed tissue-like structures seems to be a backward step. Thermoresponsive substrates can be created so that cells adhere and proliferate at the culture temperature, and then release the cultured cell sheets on command, by cooling below the LCST. These cell ...
Traffic into silence: endomembranes and
Traffic into silence: endomembranes and

... temporal compartmentalization of macromolecule synthesis, sorting, delivery, and degradation. It consists of a variety of organelles that are connected either directly or through transport vesicles, the formation of which necessitates the selective recruitment of coat proteins (clathrin, COPI, COPII ...
Colorado Agriscience Curriculum
Colorado Agriscience Curriculum

... What is cancer? Certain genes contain the information necessary to make the proteins that regulate cell growth and division. If one of these genes is mutated, the protein may not function, and regulation of cell growth and division can be disrupted. Cancer is the uncontrolled growth of cells. Some m ...
49 Localization of enzymes in certain secretory cells of Helix
49 Localization of enzymes in certain secretory cells of Helix

... phosphatase is present in smooth lamellar aggregates, and the TPPase activity in membrane-bounded, spheroidal lipochondria, similar to the mixed lipid globules of Helix. However, in the spermatid of Helix, alkaline phosphatase and TPPase are localized in the Golgi lamellae; acid phosphatase is not p ...
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Endomembrane system

The endomembrane system is composed of the different membranes that are suspended in the cytoplasm within a eukaryotic cell. These membranes divide the cell into functional and structural compartments, or organelles. In eukaryotes the organelles of the endomembrane system include: the nuclear membrane, the endoplasmic reticulum, the Golgi apparatus, lysosomes, vesicles, endosomes and the cell membrane. The system is defined more accurately as the set of membranes that form a single functional and developmental unit, either being connected directly, or exchanging material through vesicle transport. Importantly, the endomembrane system does not include the membranes of mitochondria or chloroplasts.The nuclear membrane contains two lipid bilayers that encompass the contents of the nucleus. The endoplasmic reticulum (ER) is a synthesis and transport organelle that branches into the cytoplasm in plant and animal cells. The Golgi apparatus is a series of multiple compartments where molecules are packaged for delivery to other cell components or for secretion from the cell. Vacuoles, which are found in both plant and animal cells (though much bigger in plant cells), are responsible for maintaining the shape and structure of the cell as well as storing waste products. A vesicle is a relatively small, membrane-enclosed sac that stores or transports substances. The cell membrane, is a protective barrier that regulates what enters and leaves the cell. There is also an organelle known as the Spitzenkörper that is only found in fungi, and is connected with hyphal tip growth.In prokaryotes endomembranes are rare, although in many photosynthetic bacteria the plasma membrane is highly folded and most of the cell cytoplasm is filled with layers of light-gathering membrane. These light-gathering membranes may even form enclosed structures called chlorosomes in green sulfur bacteria.The organelles of the endomembrane system are related through direct contact or by the transfer of membrane segments as vesicles. Despite these relationships, the various membranes are not identical in structure and function. The thickness, molecular composition, and metabolic behavior of a membrane are not fixed, they may be modified several times during the membrane's life. One unifying characteristic the membranes share is a lipid bilayer, with proteins attached to either side or traversing them.
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