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Adenovirus RIDα regulates endosome maturation by mimicking GTP
Adenovirus RIDα regulates endosome maturation by mimicking GTP

... to Rab7 and is not catalytically active. We show that RIDα compensates for reduced Rab7 or dominant-negative (DN) Rab7(T22N) expression. In vitro, Cu2+ binding to RIDα residues His75 and His76 facilitates the RILP interaction. Site-directed mutagenesis of these His residues results in the loss of RI ...
Do you agree or disagree?
Do you agree or disagree?

... How does cell size affect the transport of materials? The ratio of surface area to volume limits the size of a cell. In a smaller cell, the high surface-area-to-volume ratio allows materials to move easily to all parts of a cell. ...
Interactions between Human Two-pore Channels and Nonaspanin
Interactions between Human Two-pore Channels and Nonaspanin

... Two pore channels, a family consisting of TPC1, TPC2, TPC3, are cation-selective ion channels. Structurally, they contain two six transmembrane domains and form a dimer in the membrane (6). TPCs are found in plants and mammalian cells, and humans express two TPC isoforms TPC1 and TPC2, which locali ...
Human Monocytes Arachidonic Acid Reacylation Reactions in
Human Monocytes Arachidonic Acid Reacylation Reactions in

... AA incorporation was measured in total PLs (A) or PLs classes (B), PI (s, d), PC (4, :), and PE (,, ▼). Data are shown as means 6 SD from three different determinations carried out in duplicate. pp , 0.05, significance of nonstimulated cells versus zymosan-stimulated cells at each condition. ...
pdf article
pdf article

... mutations found in biopsies? He could only think that there must be greater genetic diversity in the tumour than accounted for by linear evolution – that there must nearly always be some cells in the tumour resistant to treatment which would survive and take over. So his team asked what happened if ...
Living Cells
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... like structures. Whenever the cell is about to divide, the chromatin material gets organised into chromosomes. The nucleus plays a central role in cellular reproduction, the process by which a single cell divides and forms two new cells. It also plays a crucial part, along with the environment, in d ...
pGLO LAB EDITED by ME
pGLO LAB EDITED by ME

... calcium chloride in order to make cells that will more readily take up DNA—these are competent cells. The positive charges of the chemical partially neutralizes the negatively charged DNA and plasma membrane of the cell so that they will not repel each other, allowing the DNA to pass through tiny po ...
Ch 4: Tissues
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New astrocyte cell surface markers
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Finals – Study Guide
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Alternative translation initiation gives rise to two isoforms of Orai1
Alternative translation initiation gives rise to two isoforms of Orai1

... isoforms are ubiquitously expressed in human cell lines derived from different tissues and both localize similarly within cells as seen by confocal microscopy. In the sequence upstream of the initiation site of Orai1b, there is a poly-arginine sequence previously suggested to be involved in interact ...
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Adjusted from Momčilović et al., 2012
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... progressive loss of the dopaminergic (DA) neurons of the substantia nigra pars compacta, which project to the striatum and are responsible for movement control (Arenas, 2010; Momčilović et al., 2012), making the disease suitable for cell replacement therapy (Kriks&Studer, 2009). First attempts were ...
MS Word
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Immunoglobulin detection
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... conditions will differ depending on the source and state of the cells. For instance, when using samples from blood or lymphoid tissue, cells may be in an activated form as a consequence of an acute infection or a recent immunization/vaccination or in the form of memory cells. If cells have been acti ...
A. diffuser
A. diffuser

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Ch. 4 Powerpoint Notes - Fulton County Schools
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A Cell Type-specific Constitutive Point Mutant of the
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... mGMRa (335 amino acids) and the cytoplasmic domain of hGMRa (54 amino acids); and (iv) the pRUFNeo/Fmaha2 chimera encoding the extracellular FLAG-tagged N-terminal domain of FmGMRa (111 amino acids) and the extracellular CRM, transmembrane, and cytoplasmic domains of hGMRa (283 amino acids). A full ...
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Export To Word
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... If the teacher decides to create their own version of the Jeopardy game, the process to do so on the website (link provided) is not very time intensive. If the teacher already has the questions picked out that they would like to enter into the game (test review questions, for example) the process wi ...
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Research Article Transcription factor c

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... from carbon sources), and mixotrophic (obtaining energy from light and carbon sources) modes of growth. To decipher the TOR signaling network in Chlamydomonas, the authors screened for mutants that were hypersensitive to the antibiotic rapamycin (RAP), an established inhibitor of TOR in this organis ...
Cilia and Flagella: The Basics
Cilia and Flagella: The Basics

... Basal body (Kinetosome) located at base  9 sets of 3 microtubules in radial ...
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Amitosis

Amitosis (a- + mitosis) is absence of mitosis, the usual form of cell division in the cells of eukaryotes. There are several senses in which eukaryotic cells can be amitotic. One refers to capability for non-mitotic division and the other refers to lack of capability for division. In one sense of the word, which is now mostly obsolete, amitosis is cell division in eukaryotic cells that happens without the usual features of mitosis as seen on microscopy, namely, without nuclear envelope breakdown and without formation of mitotic spindle and condensed chromosomes as far as microscopy can detect. However, most examples of cell division formerly thought to belong to this supposedly ""non-mitotic"" class, such as the division of unicellular eukaryotes, are today recognized as belonging to a class of mitosis called closed mitosis. A spectrum of mitotic activity can be categorized as open, semi-closed, and closed mitosis, depending on the fate of the nuclear envelope. An exception is the division of ciliate macronucleus, which is not mitotic, and the reference to this process as amitosis may be the only legitimate use of the ""non-mitotic division"" sense of the term today. In animals and plants which normally have open mitosis, the microscopic picture described in the 19th century as amitosis most likely corresponded to apoptosis, a process of programmed cell death associated with fragmentation of the nucleus and cytoplasm. Relatedly, even in the late 19th century cytologists mentioned that in larger life forms, amitosis is a ""forerunner of degeneration"".Another sense of amitotic refers to cells of certain tissues that are usually no longer capable of mitosis once the organism has matured into adulthood. In humans this is true of various muscle and nerve tissue types; if the existing ones are damaged, they cannot be replaced with new ones of equal capability. For example, cardiac muscle destroyed by heart attack and nerves destroyed by piercing trauma usually cannot regenerate. In contrast, skin cells are capable of mitosis throughout adulthood; old skin cells that die and slough off are replaced with new ones. Human liver tissue also has a sort of dormant regenerative ability; it is usually not needed or expressed but can be elicited if needed.
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