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DNA-Based Markers and Their Use in Dairy
DNA-Based Markers and Their Use in Dairy

... The explosion of genetic information and sequence data over the past decade has resulted in the recent availability of some DNA-based tests for production traits such as milk yield. These tests are based on research studies showing that specific DNA variations are associated with a positive effect o ...
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... A. They pass on to their offspring new characteristics they acquired during their lifetimes. B. They are better adapted to exist in their environment than others. C. They do not pass on to their offspring new characteristics they have acquired during their lifetimes. D. They tend to produce fewer of ...
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... • Law of Segregation - The two traits for a characteristic separate during the formation of eggs and sperm. Pg 177 ...
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... What are the possible genotypes and phenotypes of the children of parents that are heterozygous for round eyes with a blue body and purebred for round eyes and hybrid for a yellow body? ...
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... • Although the chromatin modifications just discussed do not alter DNA sequence, they may be passed to future generations of cells. • The inheritance of traits transmitted by mechanisms not directly involving the nucleotide sequence is called epigenetic inheritance. ...
PTK7 domain involvement in planar cell polarity
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... When observing the functional and morphological deficits of PCP core gene mutant vertebrates, you see very similar deficits between different genes. In vangL mutant zebrafish, embryos demonstrated neural tube morphological defects (Hayes et al 2013). PTK7 was found to be a novel regulator in the pla ...
Identifying differentially expressed sets of genes in microarray
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click here
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... Dependence of the X:AA estimates on the RPKM threshold. The tissue-averaged X:AA estimates are shown (black) as a function of the minimal RPKM threshold, from 0 (all genes, including those with undetected expression) to RPKM ≥2. The error bars correspond to the s.e.m. between different tissues. The ...
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... *Note that the DNA segment being tested shows a positive hybridization signal to clones 1, 3, 4, and 7. Each of these clones contains chromosome 9, whereas clones 2, 5, 6, and 8 do not contain this chromosome. This pattern localizes the DNA segment to chromosome 9. ...
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Site-specific recombinase technology



Nearly every human gene has a counterpart in the mouse (regardless of the fact that a minor set of orthologues had to follow species specific selection routes). This made the mouse the major model for elucidating the ways in which our genetic material encodes information. In the late 1980s gene targeting in murine embryonic stem (ES-)cells enabled the transmission of mutations into the mouse germ line and emerged as a novel option to study the genetic basis of regulatory networks as they exist in the genome. Still, classical gene targeting proved to be limited in several ways as gene functions became irreversibly destroyed by the marker gene that had to be introduced for selecting recombinant ES cells. These early steps led to animals in which the mutation was present in all cells of the body from the beginning leading to complex phenotypes and/or early lethality. There was a clear need for methods to restrict these mutations to specific points in development and specific cell types. This dream became reality when groups in the USA were able to introduce bacteriophage and yeast-derived site-specific recombination (SSR-) systems into mammalian cells as well as into the mouse
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