• Study Resource
  • Explore Categories
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
Serpentine plants survive harsh soils thanks to borrowed
Serpentine plants survive harsh soils thanks to borrowed

... analysed the genomes of plants that grow in harsh, Austria, which is an extreme habitat even for this species," explains Dr Bomblies. "It was still growing serpentine soils to find out how they survive in there when we visited the same site in 2010, so we such conditions. It appears that they have u ...
as a PDF
as a PDF

... dutch haplotype (22-37-13) can best be explained by independent introduction, although there is also a possibility of a mutation in the original haplotype. The ∆F508 mutation is a very old mutation, which has been introduced at least 52,000 years ago in Europe [21]. Much variation is observed in int ...
Genes Code for Proteins
Genes Code for Proteins

... To determine what effect a gene has upon the phenotype, it is essential to characterize a null mutant. Generally, if a null mutant fails to affect a phenotype, we may safely conclude that the gene function is not necessary. Some genes have overlapping functions, though, and removal of one gene is no ...
A Tn 10-lacZ-kanR-URA3 Gene Fusion Transposon for Insertion Mutagenesis and Fusion Analysis of Yeast and Bacterial Genes.
A Tn 10-lacZ-kanR-URA3 Gene Fusion Transposon for Insertion Mutagenesis and Fusion Analysis of Yeast and Bacterial Genes.

... cloned yeast genes; it can equally well be used for analysis of prokaryotic genes. We have applied this element to analysis of the LEU2, RADSO, and CDC48 genes of Saccharomyces cerevisiae. This transposon, nicknamed mini-Tn 10-LUK, contains a lacZ gene without efficient transcription or translation ...
Dynamics of transcription and mRNA export
Dynamics of transcription and mRNA export

... transcription factors could occur in the same phase of the cycle (as was the case for 13/56 genes) or also bind to genes expressed in subsequent phases (24/56 genes), providing a trigger to move to the next phase. The lag between transcription factor binding and gene expression, although highly repr ...
Neurospora genetic nomenclature
Neurospora genetic nomenclature

... 1.5. Genes in ectopic positions. A Neurospora gene that has been integrated ectopically is designated by appending (EC) to the gene symbol, e.g., am(EC). The genotype of a strain with a gene deleted from its normal position and a wild type copy of the same gene inserted elsewhere in the genome would ...
Pierce chapter 9
Pierce chapter 9

... – Nullisomy 2n – 2 – missing both members of a homologous pair – Monosomy 2n – 1 – missing one chromosome – Trisomy 2n + 1 – one extra chromosome – Tetrasomy – 2n + 2 – two extra chromosomes of the same type/homologous ...
Phylogenetic Tree Construction using Pathway Analysis
Phylogenetic Tree Construction using Pathway Analysis

... Pathway takes into account multiple genes ...
Genetic Algorithms
Genetic Algorithms

... produce fit solutions for specific tasks [Fogel, Owens, Walsh 1966]  Genetic Algorithms: Abstraction and formalisation of natural-adaptation mechanisms for general purpose computations [Holand 1962] … as opposed to problem-specific algorithm development  Other independent efforts for evolution-ins ...
Answers to Mastering Concepts Questions
Answers to Mastering Concepts Questions

... the two homozygotes. This goes against the idea that two alleles should produce only two phenotypes, with one allele dominant over the other. Instead of a 3:1 phenotypic ratio, the ratio is 1:2:1. Codominance: The heterozygote fully expresses two different alleles. This goes against the idea that tw ...
Document
Document

... • RSVP Ingrid Regarding Dinner This Week ...
Epigenetic
Epigenetic

... 1942 to describe “the interactions of genes with their environment that bring the phenotype into being”. Waddington’s classical epigenetic landscape: in 1957, Waddington proposed the concept of an epigenetic landscape to represent the process of cellular decision-making during development. At variou ...
CHAPTER 16 Advanced Gene Mapping in Eukaryotes
CHAPTER 16 Advanced Gene Mapping in Eukaryotes

... 2. Centromeres separate just before the second meiotic division, and so spores in the top of the ascus have the centromere from one parent, while those below have the other parent’s centromere. 3. In this example, mating type (A and a) is one locus, and the centromere is another. a. If no crossover ...
Lesson 3
Lesson 3

... Inheriting Traits • No two individuals are exactly alike. Even identical twins have some differences. • Heredity is a significant factor that influences the way an individual develops. • Some traits that you inherit from your parents are your eye and hair color. • Environment can also influence inhe ...
Chapter 19 Lesson 3 heredity and genetics
Chapter 19 Lesson 3 heredity and genetics

... Inheriting Traits • No two individuals are exactly alike. Even identical twins have some differences. • Heredity is a significant factor that influences the way an individual develops. • Some traits that you inherit from your parents are your eye and hair color. • Environment can also influence inhe ...
Genetics IV: Biochemical Genetics
Genetics IV: Biochemical Genetics

... In order to do this, first test whether the mutations are causing a recessive phenotype. 1) Test of Recessivity: - loss of enzyme function is usually recessive to wild type phenotype - usually 50% of a gene product is enough to show a wt phenotype for an enzymatic defect – usually only 1 wt copy of ...
Case Report
Case Report

... Figure 2. Automated DNA sequencing result of the KCNQ1 gene, A. Normal subject B. Patient. emotional situations, and rarely occur during rest or sleep without any other symptom. In some cases, TdP changes to ventricular fibrillation and causes cardiac arrest or sudden death (6). Approximately 50% of ...
Gene Section TTL (twelve-thirteen translocation leukemia) Atlas of Genetics and Cytogenetics
Gene Section TTL (twelve-thirteen translocation leukemia) Atlas of Genetics and Cytogenetics

Heredity
Heredity

... (The small segments of a DNA molecule that contain specific trait information) ...
Exceptions to Mendel`s Laws
Exceptions to Mendel`s Laws

... Mendel chose traits in peas that showed 2 distinct forms. Not all genes exhibit such simple inheritance. ...
04BIO201 Exam 1 key
04BIO201 Exam 1 key

... gene encoding tyrosinase. However, a study from 1952 reported that two albino parents produced three normally pigmented children. How would you explain this phenomenon at a genetic level. In your answer, make sure you indicate how pigment formation is inherited based on the data from the study cited ...
manual K. lactis Protein Expression Kit E1000S
manual K. lactis Protein Expression Kit E1000S

... and that may have desired post-translational modifications (e.g. glycosylation) that cytosolic proteins do not. Protein secretion using pKLAC2 is achieved by generating a fusion between the protein of interest and the a-MF secretion domain present in the vector. To do this, a gene or open reading fr ...
Chapter 15 Chromosomal Basis of Heredity
Chapter 15 Chromosomal Basis of Heredity

... Relating Mendelian Inheritance to the Behavior of Chromosomes 1. Explain how the observations of cytologists and geneticists provided the basis for the chromosome theory of inheritance. 2. Explain why Drosophila melanogaster is a good experimental organism for genetic studies. 3. Explain why linked ...
Unit 8.2: Human Inheritance
Unit 8.2: Human Inheritance

... human traits are inherited in different ways. Some human traits have simple inheritance patterns like the traits that Gregor Mendel studied in pea plants. Other human traits have more complex inheritance patterns. Mendelian Inheritance in Humans Mendelian inheritance refers to the inheritance of tra ...
Bchem 4200 Part13 - U of L Class Index
Bchem 4200 Part13 - U of L Class Index

... → Leaving the target side might also involve sliding etc. Sliding accelerates target site location: → under optimum conditions it allows for scanning of ~106 bases per binding event. → but it’s a random walk →the effective sliding distance is much shorter ~ 1000 bp → ionic conditions, in particular ...
< 1 ... 522 523 524 525 526 527 528 529 530 ... 1288 >

Site-specific recombinase technology



Nearly every human gene has a counterpart in the mouse (regardless of the fact that a minor set of orthologues had to follow species specific selection routes). This made the mouse the major model for elucidating the ways in which our genetic material encodes information. In the late 1980s gene targeting in murine embryonic stem (ES-)cells enabled the transmission of mutations into the mouse germ line and emerged as a novel option to study the genetic basis of regulatory networks as they exist in the genome. Still, classical gene targeting proved to be limited in several ways as gene functions became irreversibly destroyed by the marker gene that had to be introduced for selecting recombinant ES cells. These early steps led to animals in which the mutation was present in all cells of the body from the beginning leading to complex phenotypes and/or early lethality. There was a clear need for methods to restrict these mutations to specific points in development and specific cell types. This dream became reality when groups in the USA were able to introduce bacteriophage and yeast-derived site-specific recombination (SSR-) systems into mammalian cells as well as into the mouse
  • studyres.com © 2026
  • DMCA
  • Privacy
  • Terms
  • Report