VanBUG_quackenbush
... Unless a reviewer has the courage to give you unqualified praise, I say ignore the bastard. ...
... Unless a reviewer has the courage to give you unqualified praise, I say ignore the bastard. ...
Behavioral Genetics
... the body’s cells divide through a process called mitosis, in which the cell’s chromosomes duplicate themselves so that each new cell contains copies of the twenty-three pairs of chromosomes in the original. A different kind of cell division occurs when a male’s sperm cells and a female’s egg cells ( ...
... the body’s cells divide through a process called mitosis, in which the cell’s chromosomes duplicate themselves so that each new cell contains copies of the twenty-three pairs of chromosomes in the original. A different kind of cell division occurs when a male’s sperm cells and a female’s egg cells ( ...
Access to the Maize Genome: An Integrated Physical and Genetic Map
... score, and database links for more information, e.g. MaizeDB link to map details; CUGI link to BAC contigs; GenBank; and ZmDB (Zea mays database at Iowa State University) links for sequence and clone information. Maps can be viewed at MaizeDB in three ways. For any single map, chromosome-specific vi ...
... score, and database links for more information, e.g. MaizeDB link to map details; CUGI link to BAC contigs; GenBank; and ZmDB (Zea mays database at Iowa State University) links for sequence and clone information. Maps can be viewed at MaizeDB in three ways. For any single map, chromosome-specific vi ...
14 Phylogenomic Approach to the Evolutionary Dynamics of Gene
... 2000). It is currently unknown if the small, streamlined genomes of birds deviate from this pattern, given the lower number of total genes, paucity of transposable elements, and highly recombinant microchromosomes found in chicken. Here we explore the evolution of chicken gene families within the la ...
... 2000). It is currently unknown if the small, streamlined genomes of birds deviate from this pattern, given the lower number of total genes, paucity of transposable elements, and highly recombinant microchromosomes found in chicken. Here we explore the evolution of chicken gene families within the la ...
Sequences of flavivirus-related RNA viruses persist in DNA form
... and Aedes aegypti mosquitoes, demonstrating for the first time an integration into a eukaryotic genome of a multigenic sequence from an RNA virus that replicates without a recognized DNA intermediate. In the Aedes albopictus C6/36 cell line, an open reading frame (ORF) of 1557 aa with protease/helic ...
... and Aedes aegypti mosquitoes, demonstrating for the first time an integration into a eukaryotic genome of a multigenic sequence from an RNA virus that replicates without a recognized DNA intermediate. In the Aedes albopictus C6/36 cell line, an open reading frame (ORF) of 1557 aa with protease/helic ...
Genetic analysis of TTF2 gene in congenital hypothyroid infants with
... gene “TTF2” are rare. This finding is well-suited with results of previous mutational analysis of TTF2 (21-23). Also, in recent years expansion of trinucleotide repeats encoding polyA tracts have been reported to be the cause of some disease through the alanine containing proteins as TTF2.24 It is s ...
... gene “TTF2” are rare. This finding is well-suited with results of previous mutational analysis of TTF2 (21-23). Also, in recent years expansion of trinucleotide repeats encoding polyA tracts have been reported to be the cause of some disease through the alanine containing proteins as TTF2.24 It is s ...
Mitosis in Drosophila development - Journal of Cell Science
... mutations in the cyclin A gene utilise maternally-provided cyclin A to complete up to 15 rounds of division, after which no mitotic figures can be seen (Lehner and O ’Farrell, 1989). We also have cloned the gene for cyclin A together with the cyclin B gene of Drosophila (Whitfield et al. 1989). Both ...
... mutations in the cyclin A gene utilise maternally-provided cyclin A to complete up to 15 rounds of division, after which no mitotic figures can be seen (Lehner and O ’Farrell, 1989). We also have cloned the gene for cyclin A together with the cyclin B gene of Drosophila (Whitfield et al. 1989). Both ...
Genome-wide expression analysis of cultured
... METHODS: To address this issue, four RNA samples from trisomy 21 placentas and four samples from normal first trimester pregnancies were analyzed using Affymetrix U95v2 microarray. Statistical and bioinformatic analyses were employed to compare global gene expression, functional classes, and pathway ...
... METHODS: To address this issue, four RNA samples from trisomy 21 placentas and four samples from normal first trimester pregnancies were analyzed using Affymetrix U95v2 microarray. Statistical and bioinformatic analyses were employed to compare global gene expression, functional classes, and pathway ...
printer-friendly version of benchmark
... was DNA until the 1950s. Alfred Hershey and Martha Chase proved that DNA, not protein was the genetic material in viruses. This experiment led most scientists to believe DNA was the genetic material for all life. Soon after Hershey and Chase’s discovery, two scientists named James Watson and Francis ...
... was DNA until the 1950s. Alfred Hershey and Martha Chase proved that DNA, not protein was the genetic material in viruses. This experiment led most scientists to believe DNA was the genetic material for all life. Soon after Hershey and Chase’s discovery, two scientists named James Watson and Francis ...
The evolution of sex chromosomes: similarities and differences
... DNA sequences, estimating divergence between homologous X and Y sequences, and assuming a molecular clock – heteromorphism can evolve rapidly, e.g. by chromosome fusions ...
... DNA sequences, estimating divergence between homologous X and Y sequences, and assuming a molecular clock – heteromorphism can evolve rapidly, e.g. by chromosome fusions ...
Correlations Between Gene Expression and Gene Conservation in
... (P < 10ⳮ21). Moreover, pombe-specific genes were underrepresented among genes repressed during sexual differentiation, contributing only 5.9% of those genes (P < 10ⳮ7). We defined “pombe-specific genes” as those not shared with the S. cerevisiae and C. elegans genomes. To confirm these results, we u ...
... (P < 10ⳮ21). Moreover, pombe-specific genes were underrepresented among genes repressed during sexual differentiation, contributing only 5.9% of those genes (P < 10ⳮ7). We defined “pombe-specific genes” as those not shared with the S. cerevisiae and C. elegans genomes. To confirm these results, we u ...
The Polymerase Chain Reaction
... TPA-25 insertion were screened. If the TPA-25 insertion was present than the bands should be a size of 400bp. If the TPA-25 insertion was absent than it should be only 100bp long. This was why the B+H was used, because the B+H produces 493bp and 125bp. If there was only 1 band visible, as with stu ...
... TPA-25 insertion were screened. If the TPA-25 insertion was present than the bands should be a size of 400bp. If the TPA-25 insertion was absent than it should be only 100bp long. This was why the B+H was used, because the B+H produces 493bp and 125bp. If there was only 1 band visible, as with stu ...
... I can evaluate a claim or argument based on its support (e.g. is the evidence necessary; irrelevant). 7. Each sentence provides evidence the Patriots may have deliberately cheated EXCEPT: (A) It found Brady was “likely generally aware” that team workers had conspired to let the air out of the Patrio ...
Supplementary Material
... 99.7% (82694/82922) of the abstracts were affected by an ambiguity between a gene symbol and a general English word, and 99.8% (82736/82922) were affected by an ambiguity between a gene symbol and a UMLS term. For the fly organism, both numbers were also over 99%, while the number was much less for ...
... 99.7% (82694/82922) of the abstracts were affected by an ambiguity between a gene symbol and a general English word, and 99.8% (82736/82922) were affected by an ambiguity between a gene symbol and a UMLS term. For the fly organism, both numbers were also over 99%, while the number was much less for ...
Document
... i. loss of variation per generation is 1-1/(2N). ii. Waiting time for random alleles to find a common ancestor is 2N. Factors that influences Ne: i. Variance in offspring. WF: 1. If variance is higher, then effective population size is smaller. ii. Population size variation - example k cycle: N1, N2 ...
... i. loss of variation per generation is 1-1/(2N). ii. Waiting time for random alleles to find a common ancestor is 2N. Factors that influences Ne: i. Variance in offspring. WF: 1. If variance is higher, then effective population size is smaller. ii. Population size variation - example k cycle: N1, N2 ...
Snork Activity
... sequence of amino acids in proteins. The sequence of DNA is the most important part of determining what proteins are synthesized. During transcription, which takes place in the nucleus of the cell, messenger RNA (mRNA) molecules are built along the DNA sequence into a single RNA strand. mRNA leave ...
... sequence of amino acids in proteins. The sequence of DNA is the most important part of determining what proteins are synthesized. During transcription, which takes place in the nucleus of the cell, messenger RNA (mRNA) molecules are built along the DNA sequence into a single RNA strand. mRNA leave ...
GeneticVariation03
... The five major vertebrate classes exist due to evolutionary change. This change is, in turn, caused by deterministic and stochastic factors according to the process of natural selection. Natural selection can be summarized in 3 basic steps: 1. Variation 2. Selection 3. Reproduction The source of var ...
... The five major vertebrate classes exist due to evolutionary change. This change is, in turn, caused by deterministic and stochastic factors according to the process of natural selection. Natural selection can be summarized in 3 basic steps: 1. Variation 2. Selection 3. Reproduction The source of var ...
Identifying a Novel Isoform of the AZIN1 Gene by Combining High
... reading frame that would change the terminus of the subsequent protein from Ser-Asp-Glu-Asp-stop to PheArg-stop. Follow-up studies could validate this finding on the protein level and then measure gene expression of this new isoform in various tissues, subjects, and time-points. Moreover, the method ...
... reading frame that would change the terminus of the subsequent protein from Ser-Asp-Glu-Asp-stop to PheArg-stop. Follow-up studies could validate this finding on the protein level and then measure gene expression of this new isoform in various tissues, subjects, and time-points. Moreover, the method ...
Searching for fossil genes
... not need a source of vitamin C in their diet. The GULO gene codes for an enzyme, Lgulonolactone oxidase, involved in vitamin C synthesis. The GULO gene is present in mice and most other mammals, but is either missing, or is nonfunctional, in some mammals. These animals cannot make their own vitamin ...
... not need a source of vitamin C in their diet. The GULO gene codes for an enzyme, Lgulonolactone oxidase, involved in vitamin C synthesis. The GULO gene is present in mice and most other mammals, but is either missing, or is nonfunctional, in some mammals. These animals cannot make their own vitamin ...
Mutation, Repair, and Recombination
... Based on the mode of action of aflatoxin (Figure 16-16), propose a scenario that explains its response in the Ames test (Figure 16-18). Answer: Aflatoxin B1 becomes covalently attached to guanine residues in the DNA. The addition of the aflatoxin adduct destabilizes the N-glycosidic bond, leaving an ...
... Based on the mode of action of aflatoxin (Figure 16-16), propose a scenario that explains its response in the Ames test (Figure 16-18). Answer: Aflatoxin B1 becomes covalently attached to guanine residues in the DNA. The addition of the aflatoxin adduct destabilizes the N-glycosidic bond, leaving an ...
Plants in Action
... demonstrate that determination occurs much earlier, at P1–2. Clearly, much remains to be discovered about the timing of these processes and of the nature of communication between cells that allows coordinated formation of organs. ...
... demonstrate that determination occurs much earlier, at P1–2. Clearly, much remains to be discovered about the timing of these processes and of the nature of communication between cells that allows coordinated formation of organs. ...
Site-specific recombinase technology
Nearly every human gene has a counterpart in the mouse (regardless of the fact that a minor set of orthologues had to follow species specific selection routes). This made the mouse the major model for elucidating the ways in which our genetic material encodes information. In the late 1980s gene targeting in murine embryonic stem (ES-)cells enabled the transmission of mutations into the mouse germ line and emerged as a novel option to study the genetic basis of regulatory networks as they exist in the genome. Still, classical gene targeting proved to be limited in several ways as gene functions became irreversibly destroyed by the marker gene that had to be introduced for selecting recombinant ES cells. These early steps led to animals in which the mutation was present in all cells of the body from the beginning leading to complex phenotypes and/or early lethality. There was a clear need for methods to restrict these mutations to specific points in development and specific cell types. This dream became reality when groups in the USA were able to introduce bacteriophage and yeast-derived site-specific recombination (SSR-) systems into mammalian cells as well as into the mouse