New Gene for Bacterial Blight Resistance in Rice Located
... have the LRR motif according to the structures of cloned R genes; this suggests that there is at least one NBS-LRR type multiplegene family in the centromeric region of chromosome 12. Different copies of genes in the multiple-R-gene family or the alleles of R loci are commonly the sources for the di ...
... have the LRR motif according to the structures of cloned R genes; this suggests that there is at least one NBS-LRR type multiplegene family in the centromeric region of chromosome 12. Different copies of genes in the multiple-R-gene family or the alleles of R loci are commonly the sources for the di ...
Prentice Hall Biology - Mid
... -which will separate into different electrophoresis patterns -a DNA fingerprint If there is only a small sample of DNA available- more copies can be made by PCR -polymerase chain reaction (p371) ...
... -which will separate into different electrophoresis patterns -a DNA fingerprint If there is only a small sample of DNA available- more copies can be made by PCR -polymerase chain reaction (p371) ...
Chromosomal G + C Content Evolution in Yeasts
... reduced. We propose that these GC-poor troughs indicate the positions of centromeres because in Y. lipolytica they coincide with the five experimentally identified centromeres. In P. stipitis, the troughs contain clusters of the retrotransposon Tps5. Likewise, in Debaryomyces hansenii, there is one ...
... reduced. We propose that these GC-poor troughs indicate the positions of centromeres because in Y. lipolytica they coincide with the five experimentally identified centromeres. In P. stipitis, the troughs contain clusters of the retrotransposon Tps5. Likewise, in Debaryomyces hansenii, there is one ...
Gene Pool Recombination in Genetic Algorithms
... system by difference or differential equations. Analyzing GAs that use both recombination and selection turns out to be especially difficult. The problem is that the mating of two genotypes creates a complex linkage between genes at different loci. This linkage is very hard to model and represents t ...
... system by difference or differential equations. Analyzing GAs that use both recombination and selection turns out to be especially difficult. The problem is that the mating of two genotypes creates a complex linkage between genes at different loci. This linkage is very hard to model and represents t ...
A catalogue of imprinted genes and parent-of
... from both alleles in the liver and choroid plexus. Similarly, the absence of imprinting in some tissues obviously does not exclude imprinting in other tissues. For example, the Angelman syndrome gene, UBE3A, was thought not to be imprinted until allele-specific transcription was detected in the brai ...
... from both alleles in the liver and choroid plexus. Similarly, the absence of imprinting in some tissues obviously does not exclude imprinting in other tissues. For example, the Angelman syndrome gene, UBE3A, was thought not to be imprinted until allele-specific transcription was detected in the brai ...
Leukaemia Section T-cell prolymphocytic leukemia (T-PLL) Atlas of Genetics and Cytogenetics
... exceeding 100x109/l; T-cell prolymphocytes have the same morphologic features than B-cell prolymphocytes; a small cell variant of T-PLL has been described. Prognosis Evolution: progresses rapidly and is generally more aggressive than B-PLL; prognosis: poor response to chemotherapy is observed; media ...
... exceeding 100x109/l; T-cell prolymphocytes have the same morphologic features than B-cell prolymphocytes; a small cell variant of T-PLL has been described. Prognosis Evolution: progresses rapidly and is generally more aggressive than B-PLL; prognosis: poor response to chemotherapy is observed; media ...
09:45 PATO: An Ontology of Phenotypic Qualities
... Phenotype And Trait Ontology (PATO) • An ontology of phenotypic qualities, which can be shared across different species and domains of knowledge. • Qualities are the basic entities that we can perceive and/or measure: – colors, sizes, masses, lengths etc. • Qualities inhere to entities: every entit ...
... Phenotype And Trait Ontology (PATO) • An ontology of phenotypic qualities, which can be shared across different species and domains of knowledge. • Qualities are the basic entities that we can perceive and/or measure: – colors, sizes, masses, lengths etc. • Qualities inhere to entities: every entit ...
The Complete Mitochondrial DNA (mtDNA) of the Donkey and
... it has been shown previously (Arnason and Johnsson 1992; Cao et al. 1994) that individual mtDNA genes may provide different topologies for ordinal relationships among mammals. In the present paper we address this issue from another angle by comparing the differences between individual peptide-coding ...
... it has been shown previously (Arnason and Johnsson 1992; Cao et al. 1994) that individual mtDNA genes may provide different topologies for ordinal relationships among mammals. In the present paper we address this issue from another angle by comparing the differences between individual peptide-coding ...
DNA Profiling
... – 2010 – markers on the Y chromosome of the suspect of a crime’s DNA were consistent with those on the Y chromosome of the Grim Sleeper and provided a lead – Police officer posed as a waiter at a pizza restaurant and obtained DNA evidence from the suspect ...
... – 2010 – markers on the Y chromosome of the suspect of a crime’s DNA were consistent with those on the Y chromosome of the Grim Sleeper and provided a lead – Police officer posed as a waiter at a pizza restaurant and obtained DNA evidence from the suspect ...
"Genetic Redundancy".
... studies implicated the loss of ACTN3 (a-actinin-3) in muscular dystrophy, and other dystrophic, myopathic and neurogenic pathologies. Subsequent testing revealed that normal individuals very often shared the defective genotype, homozygous for a nonsense mutation to ACTN3. The data suggest that ACTN3 ...
... studies implicated the loss of ACTN3 (a-actinin-3) in muscular dystrophy, and other dystrophic, myopathic and neurogenic pathologies. Subsequent testing revealed that normal individuals very often shared the defective genotype, homozygous for a nonsense mutation to ACTN3. The data suggest that ACTN3 ...
Pharmacogenomics Presenter Guide
... drug or medicine. Genomics, which sounds similar to the word genetics, means the study of genes. So, the word pharmacogenomics means personalized medicine that is tailored to you the individual, based on the genes you have. Your genes will determine how you respond to a drug, is the drug toxic, is t ...
... drug or medicine. Genomics, which sounds similar to the word genetics, means the study of genes. So, the word pharmacogenomics means personalized medicine that is tailored to you the individual, based on the genes you have. Your genes will determine how you respond to a drug, is the drug toxic, is t ...
Mutation of the p53 Gene Is Not a Typical Feature of Hodgkin and
... from single cells was performed by seminested PCR. The primers hybridized in the intronic sequences flanking the exons. Three segments of the p53 gene were amplified with different primer pairs, the first (E4) containing the downstream part of exon 4, the second (E5/6) containing exons 5 and 6, and ...
... from single cells was performed by seminested PCR. The primers hybridized in the intronic sequences flanking the exons. Three segments of the p53 gene were amplified with different primer pairs, the first (E4) containing the downstream part of exon 4, the second (E5/6) containing exons 5 and 6, and ...
Optimization of the RT-PCR Method Using the TitanTM One Tube
... β-actin/B7-1 primer 72°C for 1 min (DNA synthesis) 4°C endlessly (termination of the reaction) Repeat these steps 30x. Modification of the standard RT-PCR: the “one-step RT-PCR” In this method both the cDNA synthesis and the amplification are performed with an optimized buffer and the respective enz ...
... β-actin/B7-1 primer 72°C for 1 min (DNA synthesis) 4°C endlessly (termination of the reaction) Repeat these steps 30x. Modification of the standard RT-PCR: the “one-step RT-PCR” In this method both the cDNA synthesis and the amplification are performed with an optimized buffer and the respective enz ...
Biology of Cell Killing by 1-/?-D
... this class we included cells which remained rounded for an abnormally long time (up to several times that of control cell divisions) but which were otherwise normal in appearance, as well as those mitotic cells which, while ultimately producing 2 progeny, underwent violent movements of the cell memb ...
... this class we included cells which remained rounded for an abnormally long time (up to several times that of control cell divisions) but which were otherwise normal in appearance, as well as those mitotic cells which, while ultimately producing 2 progeny, underwent violent movements of the cell memb ...
Bayesian Partition Models for Identifying Expression Quantitative
... epistasis association mapping (BEAM) model to detect epistatic interactions in genome-wide casecontrol studies, where response Y is a binary variable indicating disease status. The BEAM model can be viewed as a generalization of the naïve Bayes (NB) model, which models Pr(X|Y) instead of Pr(Y|X). Mo ...
... epistasis association mapping (BEAM) model to detect epistatic interactions in genome-wide casecontrol studies, where response Y is a binary variable indicating disease status. The BEAM model can be viewed as a generalization of the naïve Bayes (NB) model, which models Pr(X|Y) instead of Pr(Y|X). Mo ...
Digenic inheritance in medical genetics
... though good methods have been developed.4–6 In this context, ‘reduced penetrance’ means that while all or almost all affected pedigree members are modelled as having the mutant genotype at the primary locus, one or more relatives with the primary mutant genotype are unaffected; genetic modelling all ...
... though good methods have been developed.4–6 In this context, ‘reduced penetrance’ means that while all or almost all affected pedigree members are modelled as having the mutant genotype at the primary locus, one or more relatives with the primary mutant genotype are unaffected; genetic modelling all ...
Detection of 881 A→881 Mutation in Tyrosinase Gene and
... chinchilla , and in the California strain, the coat color of which is characteristic of “eight black” at the extremes. Another mutation of nt 1073 C→T is also present in Chinchilla. After five-years’ breeding, a “black ear” wool rabbit strain was developed by intercrossing wool rabbit with Yipulu st ...
... chinchilla , and in the California strain, the coat color of which is characteristic of “eight black” at the extremes. Another mutation of nt 1073 C→T is also present in Chinchilla. After five-years’ breeding, a “black ear” wool rabbit strain was developed by intercrossing wool rabbit with Yipulu st ...
Pseudogenes as regulators of biological function
... shares a similar pattern of tissue-specific expression to a pseudogene (ABCC6P1). The mRNA levels of the ABCC6 gene are reduced when transcript levels of the ABCC6 pseudogene are specifically reduced [28]. Oct4 is a pluripotency-associated transcription factor that is involved in stem cell identity ...
... shares a similar pattern of tissue-specific expression to a pseudogene (ABCC6P1). The mRNA levels of the ABCC6 gene are reduced when transcript levels of the ABCC6 pseudogene are specifically reduced [28]. Oct4 is a pluripotency-associated transcription factor that is involved in stem cell identity ...
The Functions of Introns: From Junk DNA to Designed DNA
... [GT at the start or donor (3’) end and AG at the other end, called the acceptor (5’) site] which help to identify introns for removal. The term “consensus sequence” is employed because, although the sites may consist of more than just GT donor and AG acceptor bases, so far as is known these sequence ...
... [GT at the start or donor (3’) end and AG at the other end, called the acceptor (5’) site] which help to identify introns for removal. The term “consensus sequence” is employed because, although the sites may consist of more than just GT donor and AG acceptor bases, so far as is known these sequence ...
Chapter 12
... Fig. 8.25. Interpretation of the rll frameshift mutations © 2006 Jones and Bartlett Publishers ...
... Fig. 8.25. Interpretation of the rll frameshift mutations © 2006 Jones and Bartlett Publishers ...
LEDGIN (ALLINI) Disruphon of HIV-‐1 Assembly Does Not Involve
... assembly are normal in PSIP1 -‐/-‐ cells. This is the case whether the enYre gene is deleted or only the IBD-‐encoding gene segment is deleted. We further determined that ALLINI potency for blocking ...
... assembly are normal in PSIP1 -‐/-‐ cells. This is the case whether the enYre gene is deleted or only the IBD-‐encoding gene segment is deleted. We further determined that ALLINI potency for blocking ...
Eugenic Evolution Utilizing a Domain Model / (c)
... policy (shown) generated chromosomes with fitness values approximately 10% better than those under the replace worst fitness policy. This result suggests that lowfitness individuals can contain valuable information, and are not always the best choice for extinction. 3.2.2 Two-Dimensional Rosenbrock ...
... policy (shown) generated chromosomes with fitness values approximately 10% better than those under the replace worst fitness policy. This result suggests that lowfitness individuals can contain valuable information, and are not always the best choice for extinction. 3.2.2 Two-Dimensional Rosenbrock ...
Site-specific recombinase technology
Nearly every human gene has a counterpart in the mouse (regardless of the fact that a minor set of orthologues had to follow species specific selection routes). This made the mouse the major model for elucidating the ways in which our genetic material encodes information. In the late 1980s gene targeting in murine embryonic stem (ES-)cells enabled the transmission of mutations into the mouse germ line and emerged as a novel option to study the genetic basis of regulatory networks as they exist in the genome. Still, classical gene targeting proved to be limited in several ways as gene functions became irreversibly destroyed by the marker gene that had to be introduced for selecting recombinant ES cells. These early steps led to animals in which the mutation was present in all cells of the body from the beginning leading to complex phenotypes and/or early lethality. There was a clear need for methods to restrict these mutations to specific points in development and specific cell types. This dream became reality when groups in the USA were able to introduce bacteriophage and yeast-derived site-specific recombination (SSR-) systems into mammalian cells as well as into the mouse