families and function.pptx
... – Create a model of evolu0on of func0on for every gene family • Annota0on of a tree node means “this func0on evolved on the branch prior to this node” • A NOT annota0on of a tree node means ...
... – Create a model of evolu0on of func0on for every gene family • Annota0on of a tree node means “this func0on evolved on the branch prior to this node” • A NOT annota0on of a tree node means ...
GENETICS
... evidence to a suspect or to help identify a body Inheritance Matching: used to determine paternity ...
... evidence to a suspect or to help identify a body Inheritance Matching: used to determine paternity ...
An update on ongoing projects within Biorange SP3.2.2.1
... (only the longest peptide per gene) “A”: All peptide sequences from this orthologous group (all peptides per gene) ...
... (only the longest peptide per gene) “A”: All peptide sequences from this orthologous group (all peptides per gene) ...
GENETICS & HEREDITY
... founded laws of dominant and recessive genes. Inherited traits –passed down Genes occur in pairs One is dominant and one is ...
... founded laws of dominant and recessive genes. Inherited traits –passed down Genes occur in pairs One is dominant and one is ...
Genit 1
... oppose the carrier to certain diseases more. ---- Largest chromosome is the first one (1296 gene) and the smallest is Y (46 gene). ---- Every day we are discovering new genes! ...
... oppose the carrier to certain diseases more. ---- Largest chromosome is the first one (1296 gene) and the smallest is Y (46 gene). ---- Every day we are discovering new genes! ...
Glossary (34,35)
... The existence of two or more variants of a gene, with the less common variant occurring with at least 1% frequency in the population (cf mutation); types include single nucleotide polymorphism (most common type), insertion, deletion, and tandem repeat ...
... The existence of two or more variants of a gene, with the less common variant occurring with at least 1% frequency in the population (cf mutation); types include single nucleotide polymorphism (most common type), insertion, deletion, and tandem repeat ...
Genetic Markers
... the genetic disease using hundreds of genetic markers from all over the genome. • “Brute force" approach is necessary because of the great size of the human genome (3000 megabases or 3x109bp). Using hundreds of markers ensures unknown gene will be close enough to one or two of them to show genetic l ...
... the genetic disease using hundreds of genetic markers from all over the genome. • “Brute force" approach is necessary because of the great size of the human genome (3000 megabases or 3x109bp). Using hundreds of markers ensures unknown gene will be close enough to one or two of them to show genetic l ...
Red line lesson sketch
... Paper exercises or analogies can help draw the student to the idea of just how a gene contains information, and just why we use computers to find that information. You can have students look for stop and start codons on paper, and then take them to subway to see how computational power enhances our ...
... Paper exercises or analogies can help draw the student to the idea of just how a gene contains information, and just why we use computers to find that information. You can have students look for stop and start codons on paper, and then take them to subway to see how computational power enhances our ...
In the 150 years since Darwin wrote On the Origin of Species our
... prejudice. If somebody found out their new partner had high risks of developing a disease such as schizophrenia, this could cause prejudice as to whether their partner is prepared to accept future responsibilities resulting from the surfacing of the disease, as well as consideration of whether the g ...
... prejudice. If somebody found out their new partner had high risks of developing a disease such as schizophrenia, this could cause prejudice as to whether their partner is prepared to accept future responsibilities resulting from the surfacing of the disease, as well as consideration of whether the g ...
INTERPRO An integrated resource of protein families
... They are usually well structured However, they usually have less annotation Examples: GenBank, GO (FatiGO), UniProt, InterPro, KEGG (FatiWISE) ...
... They are usually well structured However, they usually have less annotation Examples: GenBank, GO (FatiGO), UniProt, InterPro, KEGG (FatiWISE) ...
The Major Histocompatability Complex (MHC) is a protein that plays... important role in the immune response to pathogens of all...
... Holstein dairy cattle can have up to six different alleles for the MHC Class I gene per individual, though these alleles are usually not all expressed. The goal of this experiment is to determine whether the same alleles are expressed in different tissues in the Holstein body or if the allelic expre ...
... Holstein dairy cattle can have up to six different alleles for the MHC Class I gene per individual, though these alleles are usually not all expressed. The goal of this experiment is to determine whether the same alleles are expressed in different tissues in the Holstein body or if the allelic expre ...
PDF
... Vertebrate somites form via a sequential process of segmentation, which proceeds from anterior to posterior. In many species, anterior somites form more quickly than posterior ones, but whether this is functionally important, and how the switch in timing might be controlled, is unknown. Now (p. 158) ...
... Vertebrate somites form via a sequential process of segmentation, which proceeds from anterior to posterior. In many species, anterior somites form more quickly than posterior ones, but whether this is functionally important, and how the switch in timing might be controlled, is unknown. Now (p. 158) ...
Gene Maps
... • Knowing how often crossing over occurs between genes allows us to map positions of genes on chromosomes • Yes, crossing over is random…BUT the distance between two genes determines how often crossing over occurs • Frequency of crossing over: how often crossing over occurs between 2 genes. – If two ...
... • Knowing how often crossing over occurs between genes allows us to map positions of genes on chromosomes • Yes, crossing over is random…BUT the distance between two genes determines how often crossing over occurs • Frequency of crossing over: how often crossing over occurs between 2 genes. – If two ...
PDF
... Vertebrate somites form via a sequential process of segmentation, which proceeds from anterior to posterior. In many species, anterior somites form more quickly than posterior ones, but whether this is functionally important, and how the switch in timing might be controlled, is unknown. Now (p. 158) ...
... Vertebrate somites form via a sequential process of segmentation, which proceeds from anterior to posterior. In many species, anterior somites form more quickly than posterior ones, but whether this is functionally important, and how the switch in timing might be controlled, is unknown. Now (p. 158) ...
PDF
... Vertebrate somites form via a sequential process of segmentation, which proceeds from anterior to posterior. In many species, anterior somites form more quickly than posterior ones, but whether this is functionally important, and how the switch in timing might be controlled, is unknown. Now (p. 158) ...
... Vertebrate somites form via a sequential process of segmentation, which proceeds from anterior to posterior. In many species, anterior somites form more quickly than posterior ones, but whether this is functionally important, and how the switch in timing might be controlled, is unknown. Now (p. 158) ...
BioMart: The linked dataset
... Data mining in Ensembl with BioMart Worked Example – Demonstrating the Linked Dataset BioMart can federate (join together) databases, in this example we will join two different datasets, Ensembl genes and RGD (the Rat Genome Database) to identify all Ensembl genes involved in carbohydrate metabolism ...
... Data mining in Ensembl with BioMart Worked Example – Demonstrating the Linked Dataset BioMart can federate (join together) databases, in this example we will join two different datasets, Ensembl genes and RGD (the Rat Genome Database) to identify all Ensembl genes involved in carbohydrate metabolism ...
Supplementary Material for: A scaling normalization method for
... Figure S11. M-versus-A plots for the simulation of replicated Poisson distributed samples, relative to the reference. The left panel is the replicate of the reference, the middle and right panels are the two libraries from the other experimental condition compared to the reference. Here, the count ...
... Figure S11. M-versus-A plots for the simulation of replicated Poisson distributed samples, relative to the reference. The left panel is the replicate of the reference, the middle and right panels are the two libraries from the other experimental condition compared to the reference. Here, the count ...
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... each cell; once on the paternal set of chromosomes, and once on the maternal set of chromosomes. Each of these two complementary, but not quite identical genes is called an allele. One allele actively produces protein and is dominant. The other allele is dormant and is recessive. An entire semester ...
... each cell; once on the paternal set of chromosomes, and once on the maternal set of chromosomes. Each of these two complementary, but not quite identical genes is called an allele. One allele actively produces protein and is dominant. The other allele is dormant and is recessive. An entire semester ...
Accommodation in ABO-Incompatible Kidney Allografts: Graft
... • Circulating anti-blood group antibody and target blood group antigen demonstrated in all patients • 13/16 grafts had normal renal function and histology • 3 grafts with prior humoral rejection demonstrated significant glomerulopathy ...
... • Circulating anti-blood group antibody and target blood group antigen demonstrated in all patients • 13/16 grafts had normal renal function and histology • 3 grafts with prior humoral rejection demonstrated significant glomerulopathy ...
Mitochondrial genome
... Y chromosome shows the accumulation of spermatogenesis genes and an overall functional decay typical of male-specific chromosomes. active genes on NRY region classed into 3 types on the basis of tissue expression and homology to the X Class 1: housekeeping genes with ancient homology to X Class 2: ...
... Y chromosome shows the accumulation of spermatogenesis genes and an overall functional decay typical of male-specific chromosomes. active genes on NRY region classed into 3 types on the basis of tissue expression and homology to the X Class 1: housekeeping genes with ancient homology to X Class 2: ...
Gene expression profiling
In the field of molecular biology, gene expression profiling is the measurement of the activity (the expression) of thousands of genes at once, to create a global picture of cellular function. These profiles can, for example, distinguish between cells that are actively dividing, or show how the cells react to a particular treatment. Many experiments of this sort measure an entire genome simultaneously, that is, every gene present in a particular cell.DNA microarray technology measures the relative activity of previously identified target genes. Sequence based techniques, like serial analysis of gene expression (SAGE, SuperSAGE) are also used for gene expression profiling. SuperSAGE is especially accurate and can measure any active gene, not just a predefined set. The advent of next-generation sequencing has made sequence based expression analysis an increasingly popular, ""digital"" alternative to microarrays called RNA-Seq. However, microarrays are far more common, accounting for 17,000 PubMed articles by 2006.