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Feature subset selection/ ANOVA
Feature subset selection/ ANOVA

... 25. Click on the Store grouping button and close the Grouping window. 26. Click the Significance Analysis of Microarrays button ( ) on the toolbar or choose Supervised analysis | Significance analysis of microarrays from the Methods menu. 27. Click on the Paired tab and see that the pairs we just de ...
PowerPoint to accompany
PowerPoint to accompany

... Modes of Inheritance Dominant allele masks the phenotype of the recessive allele Recessive allele is expressed only if in a double dose (homozygous) Autosomal conditions are carried on a nonsex chromosome Sex-linked conditions are carried on a sex chromosome X-linked conditions are carried on the X ...
Gene Section PLAGL2 (pleomorphic adenoma gene-like 2) Atlas of Genetics and Cytogenetics
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Gene expression profiling



In the field of molecular biology, gene expression profiling is the measurement of the activity (the expression) of thousands of genes at once, to create a global picture of cellular function. These profiles can, for example, distinguish between cells that are actively dividing, or show how the cells react to a particular treatment. Many experiments of this sort measure an entire genome simultaneously, that is, every gene present in a particular cell.DNA microarray technology measures the relative activity of previously identified target genes. Sequence based techniques, like serial analysis of gene expression (SAGE, SuperSAGE) are also used for gene expression profiling. SuperSAGE is especially accurate and can measure any active gene, not just a predefined set. The advent of next-generation sequencing has made sequence based expression analysis an increasingly popular, ""digital"" alternative to microarrays called RNA-Seq. However, microarrays are far more common, accounting for 17,000 PubMed articles by 2006.
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