Bioinformatics V - Isfahan University of Medical Sciences
... than align the entire sequence. It’s able to detect relationships among sequences which share only isolated regions of similarity. Currently, it is the most popular and most accepted sequence analysis tool. ...
... than align the entire sequence. It’s able to detect relationships among sequences which share only isolated regions of similarity. Currently, it is the most popular and most accepted sequence analysis tool. ...
Understanding patterns of inheritance
... Patterns of inheritance The objectives of this presentation are to: • Understand how genes are inherited • Understand the differences between the inheritance patterns associated with Autosomal dominant, Autosomal recessive, Xlinked recessive and chromosomal abnormalities • Understand that the envir ...
... Patterns of inheritance The objectives of this presentation are to: • Understand how genes are inherited • Understand the differences between the inheritance patterns associated with Autosomal dominant, Autosomal recessive, Xlinked recessive and chromosomal abnormalities • Understand that the envir ...
Chapter 12 sec. 12.1 Sex Linked Traits
... Blood has both Multiple Alleles and is CoDominant • If you have IAIB as you genes, you have both Type A and Type B blood, also known as Type AB • If you have IAi, i is recessive to IA, so you have type A blood • Q. When would you have Type O blood? • A. When you have ii as your genotype. ...
... Blood has both Multiple Alleles and is CoDominant • If you have IAIB as you genes, you have both Type A and Type B blood, also known as Type AB • If you have IAi, i is recessive to IA, so you have type A blood • Q. When would you have Type O blood? • A. When you have ii as your genotype. ...
The Language of Heredity
... Punnett squares and the ratios they show express probability. Probability is the likelihood, or chance, of a specific outcome in relation to the total number of possible outcomes. The ratios derived from a Punnett square tell you the probability that any one offspring will get certain genes and expr ...
... Punnett squares and the ratios they show express probability. Probability is the likelihood, or chance, of a specific outcome in relation to the total number of possible outcomes. The ratios derived from a Punnett square tell you the probability that any one offspring will get certain genes and expr ...
Ontologies 2 - European Bioinformatics Institute
... Finding annotations in a paper …for B. napus PERK1 protein (Q9ARH1) In this study, we report the isolation and molecular characterization of the B. napus PERK1 cDNA, that is predicted to encode a novel receptor-like kinase. We have shown that like other plant RLKs, the kinase domain of ...
... Finding annotations in a paper …for B. napus PERK1 protein (Q9ARH1) In this study, we report the isolation and molecular characterization of the B. napus PERK1 cDNA, that is predicted to encode a novel receptor-like kinase. We have shown that like other plant RLKs, the kinase domain of ...
RNA-seq
... • SAGE, long-SAGE, MPSS • The recent developments in next-generation sequencing (NGS) have made whole transcriptomic analyses more accessible. • Does it work? • Comparison with microarrays • Advantages and disadvantages • How does it work? • Challenges ...
... • SAGE, long-SAGE, MPSS • The recent developments in next-generation sequencing (NGS) have made whole transcriptomic analyses more accessible. • Does it work? • Comparison with microarrays • Advantages and disadvantages • How does it work? • Challenges ...
Specimens - BioMed Central
... samples showing an alteration at that locus. The extent of the genome assigned to each clone was computed by assigning a genomic distance equal to half the distance to the two neighboring clones or to the end of a chromosome for clones with only one neighbor. The number of copy number transitions wa ...
... samples showing an alteration at that locus. The extent of the genome assigned to each clone was computed by assigning a genomic distance equal to half the distance to the two neighboring clones or to the end of a chromosome for clones with only one neighbor. The number of copy number transitions wa ...
Ch. 9: Presentation Slides
... – The expression in the population is a ‘bell-shaped’ curve: there are many genotypes and there are no clear phenotypic differences among them: If we want to find DNAmarkers that can help us to predict this phenotype, we are searching for several genetic loci simultaneously ...
... – The expression in the population is a ‘bell-shaped’ curve: there are many genotypes and there are no clear phenotypic differences among them: If we want to find DNAmarkers that can help us to predict this phenotype, we are searching for several genetic loci simultaneously ...
Features of Hybrids
... in the hybrid: -One type, affecting only one allele, mostly due to novel cistrans interactions -One type affecting both alleles ...
... in the hybrid: -One type, affecting only one allele, mostly due to novel cistrans interactions -One type affecting both alleles ...
Understanding Contemporary Genomics
... Certainly there is plenty of evidence for some biological claims, but I’m not sure these generally amount to anything that would count as proof. Proof in mathematics is a much more familiar idea, but in so far as it points to a logical relation between axioms and theorems, its application to contemp ...
... Certainly there is plenty of evidence for some biological claims, but I’m not sure these generally amount to anything that would count as proof. Proof in mathematics is a much more familiar idea, but in so far as it points to a logical relation between axioms and theorems, its application to contemp ...
Polyploidy
... Consequences of polyploidy (continued) Transposable elements that had been repressed within each parent lineage may be activated in hybrids, and can facilitate the movement of genes and promote unequal crossing over. Polyploidy is an important factor in speciation. In particular, sexually reproduci ...
... Consequences of polyploidy (continued) Transposable elements that had been repressed within each parent lineage may be activated in hybrids, and can facilitate the movement of genes and promote unequal crossing over. Polyploidy is an important factor in speciation. In particular, sexually reproduci ...
Repressor protein - Edwin C. Foreman High School
... – usually functions in catabolic pathways, • digesting nutrients to simpler molecules ...
... – usually functions in catabolic pathways, • digesting nutrients to simpler molecules ...
Gene Section RBM5 (RNA binding motif protein 5) in Oncology and Haematology
... in the control of cell death by apoptosis and cell proliferation. RBM5's involvement in apoptosis and malignancy has been the focus of many recent studies, with all results converging on a role for RBM5/LUCA15 as a Tumor Suppressor Gene (TSG). RBM5 splice variants have been shown to function as regu ...
... in the control of cell death by apoptosis and cell proliferation. RBM5's involvement in apoptosis and malignancy has been the focus of many recent studies, with all results converging on a role for RBM5/LUCA15 as a Tumor Suppressor Gene (TSG). RBM5 splice variants have been shown to function as regu ...
SPoRE - LCQB
... How to format the TF.txt matrix (only necessary for DSB model 7): This matrix contains the transcription factor binding sites for each gene. chr: chromosome number from 1 to N (optional - unused by SPoRE) position: position on the chromosome where the transcription factor binds to regulate the t ...
... How to format the TF.txt matrix (only necessary for DSB model 7): This matrix contains the transcription factor binding sites for each gene. chr: chromosome number from 1 to N (optional - unused by SPoRE) position: position on the chromosome where the transcription factor binds to regulate the t ...
Ask a Geneticist
... in the pair is totally random. When you do the math, this comes out to 10 trillion different possible combinations. If we had only one pair of chromosomes, the number drops to 4. Of course, none of this would matter if the chromosomes were exactly the same between mom and dad. Luckily they’re not. I ...
... in the pair is totally random. When you do the math, this comes out to 10 trillion different possible combinations. If we had only one pair of chromosomes, the number drops to 4. Of course, none of this would matter if the chromosomes were exactly the same between mom and dad. Luckily they’re not. I ...
Document
... B. TRAITS PASSING FROM PARENTS TO OFFSPRING C. PLANTS THAT ARE CROSS-POLLINATED D. THE RATIO OF DOMINANT TO RECESSIVE ...
... B. TRAITS PASSING FROM PARENTS TO OFFSPRING C. PLANTS THAT ARE CROSS-POLLINATED D. THE RATIO OF DOMINANT TO RECESSIVE ...
Determining the Role of Wnt Signaling in Zebrafish
... •All primers were successfully optimized for use in qPCR. •Oocyte collection methods were redefined to include the surrounding ovary tissue and immature oocytes as well as larger oocytes. This was required to get sufficient RNA yields, and is acceptable as the oocytes at this point do not produce th ...
... •All primers were successfully optimized for use in qPCR. •Oocyte collection methods were redefined to include the surrounding ovary tissue and immature oocytes as well as larger oocytes. This was required to get sufficient RNA yields, and is acceptable as the oocytes at this point do not produce th ...
genetic mapping
... • Morgan investigated several traits that followed an X-linked pattern of inheritance – Body color – Eye color – Wing length ...
... • Morgan investigated several traits that followed an X-linked pattern of inheritance – Body color – Eye color – Wing length ...
Gene expression and regulation
... number of subunits, including a sigma factor (transcription factor) that recognises the promoter. In eukaryotes there are three RNA polymerases: I, II and III. The process includes a proofreading mechanism. Termination. In prokaryotes there are two ways in which transcription is terminated. In ?-dep ...
... number of subunits, including a sigma factor (transcription factor) that recognises the promoter. In eukaryotes there are three RNA polymerases: I, II and III. The process includes a proofreading mechanism. Termination. In prokaryotes there are two ways in which transcription is terminated. In ?-dep ...
PowerPoint - Isaac Newton Institute
... where e01 is the probability of a false positive and e10 is the probability of a false negative. ...
... where e01 is the probability of a false positive and e10 is the probability of a false negative. ...
The logic of plant signalling
... Rick Amasino (Madison) Graham King (HRI), Mike Kearsey (Birmingham) ...
... Rick Amasino (Madison) Graham King (HRI), Mike Kearsey (Birmingham) ...
Gene Section MN1 (meningioma 1) Atlas of Genetics and Cytogenetics
... Yet uncertain; median survival 2 yrs. Cytogenetics Additional anomalies: +8. Hybrid/Mutated Gene 5’ MN1 - 3’ ETV6. Abnormal Protein N-term MN1 and most of it, comprising the glutamine/proline rich domain, fused to the DNA binding of ETV6 in C-term; nuclear protein. Oncogenesis May act as an altered ...
... Yet uncertain; median survival 2 yrs. Cytogenetics Additional anomalies: +8. Hybrid/Mutated Gene 5’ MN1 - 3’ ETV6. Abnormal Protein N-term MN1 and most of it, comprising the glutamine/proline rich domain, fused to the DNA binding of ETV6 in C-term; nuclear protein. Oncogenesis May act as an altered ...
Gene expression profiling
In the field of molecular biology, gene expression profiling is the measurement of the activity (the expression) of thousands of genes at once, to create a global picture of cellular function. These profiles can, for example, distinguish between cells that are actively dividing, or show how the cells react to a particular treatment. Many experiments of this sort measure an entire genome simultaneously, that is, every gene present in a particular cell.DNA microarray technology measures the relative activity of previously identified target genes. Sequence based techniques, like serial analysis of gene expression (SAGE, SuperSAGE) are also used for gene expression profiling. SuperSAGE is especially accurate and can measure any active gene, not just a predefined set. The advent of next-generation sequencing has made sequence based expression analysis an increasingly popular, ""digital"" alternative to microarrays called RNA-Seq. However, microarrays are far more common, accounting for 17,000 PubMed articles by 2006.