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Hierarchical clustering
Hierarchical clustering

... lower than Brauer et al’s, implies that grouping by time-of-change is at least as effective as hierarchical clustering at identifying relevant genes. • GO annotations are obtained fully automatically using StepMiner – it is not necessary to select interesting clusters manually. • Those clusters whic ...
Reproductive_technol..
Reproductive_technol..

... Q.8 Describe briefly the various procedures of AI. ...
Heredity Cloze - Science
Heredity Cloze - Science

... parent traits. Instead, one trait may dominate the other. In pea plants for example, having purple flowers is a _________________ trait so if a plant receives a purple gene from one parent and a white gene from the other parent, it will only have _________________ flowers. Mendel made another intere ...
Gene Regulation Notes
Gene Regulation Notes

... I. In prokaryotes A. occurs in response to the environment II. In eukaryotes A. occurs in response to the environment and for cell specialization B. when does regulation occur? 1. transcription-which genes get transcribed and when? 2. mRNA processing-addition of a 5’ cap, 3’ poly-A tail and removal ...
Leukaemia Section t(9;11)(p22;p15) Atlas of Genetics and Cytogenetics in Oncology and Haematology
Leukaemia Section t(9;11)(p22;p15) Atlas of Genetics and Cytogenetics in Oncology and Haematology

... Note: The gene contains at least 15 exons and 14 introns. DNA / RNA Two alternative splice variants: p75 and p52. Protein Chromatin-associated protein involved in trascriptional regulation, mRNA splicing and cell survival in vitro. Contains a PWWP domain and AT hook-like motifs. ...
Leukaemia Section t(3;21)(q26;q22) Atlas of Genetics and Cytogenetics in Oncology and Haematology
Leukaemia Section t(3;21)(q26;q22) Atlas of Genetics and Cytogenetics in Oncology and Haematology

... AML1-EVI1: 180 kDa; breakpoint after exon 5 or 6 in AML1, at the very 5' end of EVI1 → translocation protein includes N-term AML1 with the Runt domain and most of the gene EVI1, from the second untranslated exon to C-term, which includes the 2 zinc fingers. ...
Linkage Analysis and Mapping
Linkage Analysis and Mapping

... • Order of genes in correctly predicted by physical maps • Distance between genes is not always similar to physical maps – Double, triple, and more crossovers – Only 50% recombination frequency observable in a cross – Variation across chromosome in rate of recombination ...
Term Definition Heredity Passing of traits from parent to offspring
Term Definition Heredity Passing of traits from parent to offspring

... Characteristics passed on to offspring through genes Organism that always produces offspring with same form of trait as parent Segment of DNA on a chromosome that codes for a specific trait ...
and interferon-inducible bovine Mx1 promoter
and interferon-inducible bovine Mx1 promoter

... a panel of ssRNA viruses. The bovine Mx system may also offer such an innate protection, provided it shares some molecular characteristics with the ‘antiviral’ systems known so far. ...
Chapter 20~ DNA Technology & Genomics
Chapter 20~ DNA Technology & Genomics

... Part 1: Basic Biotechnology ...
D:\My Documents\Teaching\Fall05\Genetics\Test2F05.wpd
D:\My Documents\Teaching\Fall05\Genetics\Test2F05.wpd

... The brown eyes gene (symbol: bw) and the black body gene (symbol: b) are located on Drosophila chromosome 2. True-breeding flies with brown eyes were crossed with true-breeding flies with black bodies. Testcrossing the uniform wildtype F1 generation yielded the following offspring: 90 flies with bro ...
Document
Document

... different Agrobacteria (tra genes) are under the control of quorum sensing. The effect is that if one Agrobacterium strain has successfully transformed a plant, and now lives from the plant produced strange amino acid, other Agrobacteria can receive the Ti plasmid, which contains the T DNA transferr ...
bioinformatics review - e
bioinformatics review - e

... used, the result of a microarray experiment is, in most cases, a list of differentially expressed genes. An automatic ontological analysis approach has been recently proposed to help with the biological interpretation of such results. Currently, this approach is the de facto standard for the seconda ...
Leukaemia Section t(6;12)(p21;p13) in lymphoid malignancies Atlas of Genetics and Cytogenetics
Leukaemia Section t(6;12)(p21;p13) in lymphoid malignancies Atlas of Genetics and Cytogenetics

The Influence of Competition on Plant Responses to Seasonal Cues
The Influence of Competition on Plant Responses to Seasonal Cues

... assigned a competitive treatment in which a focal seed is placed in the center of the pot while the competitors fill the rest of the grid. Each focal plant will be planted with competitors that are sensitive negative, sensitive positive or insensitive RILs in all possible combinations. Thus, there a ...
RNA-seq data matrix
RNA-seq data matrix

... which are growing exponentially. A striking example is The Cancer Genome Atlas (TCGA), whose aim is to provide a comprehensive archive of biomedical data about tumors. In this work, we integrate RNA-seq and DNA-methylation experiments extracted from TCGA and perform a supervised classification analy ...
Inheritance, Genes, and Chromosomes
Inheritance, Genes, and Chromosomes

... He worked with the garden pea, which has both male and female sex organs and normally self-fertilizes. Mendel could control pollination and fertilization by removing the male organs and manually pollinating the ...
Unit 3 Practice Test
Unit 3 Practice Test

... c. crossing the organism with a homozygous recessive organism. d. observing the genotype of the progeny from any cross. ______30. Classical albinism results from a recessive allele. Which of the following is the expected ratio for the progeny when a normally pigmented male with an albino father has ...
Can Your Genes Make You Do It?
Can Your Genes Make You Do It?

... and that these genes are only part of the story. An estimated 1500 (or more) genes influence addictive behaviors (Li et al., 2008). This complexity means that a prediction about an individual’s risk is impossibly hard to make. But it does not prevent us from trying to identify specific genes associa ...
Chapter 9: Patterns of Inheritance
Chapter 9: Patterns of Inheritance

... F1 generation ...
Albinism Powerpoint
Albinism Powerpoint

...  Too little, or complete lack of, melanin ...
The exploitation of chromosome recombination between Lolium and
The exploitation of chromosome recombination between Lolium and

... medicines. Human proteins can even be made in bacteria, and this process is at present the simplest, cheapest and quickest means of doing so. However, not all proteins can be obtained in this way. This is why higher organisms – fungi, plants and animals – are also used in such processes. In these sy ...
Transcriptional regulatory networks in Saccharomyces cerevisiae
Transcriptional regulatory networks in Saccharomyces cerevisiae

... ● Identified network motifs that provide specific regulatory capacities for yeast ● These motifs can be used as building blocks to construct large network structures through an automated approach that combines genome-wide location and expression data (without prior knowledge) ● Future research will ...
CHAPTER 10
CHAPTER 10

... have been sequenced. • In 2004 the “finished” version of the human genome was reported. – It contains about 20,000 genes. – Alternate splicing of messenger RNA may account for several proteins from one gene. – Post-translational modifications also account for different protein functions. ...
The complete mitochondrial genome of the demosponge
The complete mitochondrial genome of the demosponge

... E-mail address: [email protected] (D. Huchon). These authors contributed equally to this work. ...
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Gene expression profiling



In the field of molecular biology, gene expression profiling is the measurement of the activity (the expression) of thousands of genes at once, to create a global picture of cellular function. These profiles can, for example, distinguish between cells that are actively dividing, or show how the cells react to a particular treatment. Many experiments of this sort measure an entire genome simultaneously, that is, every gene present in a particular cell.DNA microarray technology measures the relative activity of previously identified target genes. Sequence based techniques, like serial analysis of gene expression (SAGE, SuperSAGE) are also used for gene expression profiling. SuperSAGE is especially accurate and can measure any active gene, not just a predefined set. The advent of next-generation sequencing has made sequence based expression analysis an increasingly popular, ""digital"" alternative to microarrays called RNA-Seq. However, microarrays are far more common, accounting for 17,000 PubMed articles by 2006.
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