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BIOL 112 – Principles of Zoology
BIOL 112 – Principles of Zoology

... Developmental pathways consist of sequences of various regulatory steps In development, cells commit to specific fates and differentially express subsets of genes Determination Differentiation ...
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Small changes, big results: evolution of morphological discontinuity

... and identifying candidate genes responsible for morphological discontinuities in mammals and other organisms. Rather than simple mutations within structural genes, many of the mechanisms underlying change represent more subtle and complex changes involving gene regulation. Complex anatomical differe ...
Control of Gene Expression in Prokaryotes
Control of Gene Expression in Prokaryotes

... operon helps the organism produce the amino acid tryptophan from other compounds when tryptophan is not present in the cell’s environment. When tryptophan is present in adequate quantities, the operon is turned “off.” 14. What compound could serve as the corepressor of the trp operon in E. coli bas ...
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The application of Microarray in Medicine

... In this review, we have a bald look at medical applications of Microarrays. ...
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... Beadle and Tatum’s Experiment After the discovery by biologists that one gene is not necessarily responsible for the structure of an entire protein, but for each polypeptide chain making up that protein, the current one gene—one polypeptide hypothesis was adopted. This is the currently accepted the ...
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... Amplified chitinase gene sequence shared 99% homology with Musa acuminata class III acidic chitinase and beta-1,3-glucanase gene sequence was 100% homologous to Musa x paradisiaca beta-1,3-glucanase. Three nucleotide-binding sites and the leucine-rich repeat (NBS-LRR) type of putative RGCs and one s ...
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... genetic cascade specified by seven genes in Drosophila. More recently, a new class of signalling molecules, EGF receptor and Notch appears to be acting upstream of that eye specification network (Kumar and Moses, 2001). Planarians (Platyhelminthes; Turbellaria; Tricladida) belong to the Platyhelmint ...
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Variation of Traits Name: #____ Genetics and Inheritance Date

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Gene expression profiling



In the field of molecular biology, gene expression profiling is the measurement of the activity (the expression) of thousands of genes at once, to create a global picture of cellular function. These profiles can, for example, distinguish between cells that are actively dividing, or show how the cells react to a particular treatment. Many experiments of this sort measure an entire genome simultaneously, that is, every gene present in a particular cell.DNA microarray technology measures the relative activity of previously identified target genes. Sequence based techniques, like serial analysis of gene expression (SAGE, SuperSAGE) are also used for gene expression profiling. SuperSAGE is especially accurate and can measure any active gene, not just a predefined set. The advent of next-generation sequencing has made sequence based expression analysis an increasingly popular, ""digital"" alternative to microarrays called RNA-Seq. However, microarrays are far more common, accounting for 17,000 PubMed articles by 2006.
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