beautiful bicolours - tuxedo and magpie cats
... hypothesis is that the cats have the dominant white gene (the one related to deafness) and that a second gene is causing this to break down so that spotting appears. It is possible to produce coloured cats from mating two all-white cats since each parent needs only one copy of the dominant white gen ...
... hypothesis is that the cats have the dominant white gene (the one related to deafness) and that a second gene is causing this to break down so that spotting appears. It is possible to produce coloured cats from mating two all-white cats since each parent needs only one copy of the dominant white gen ...
long program - Pan
... plants. However, the molecular mechanisms that give rise to leaf developmental variation are incompletely understood. The complexity of Gene Regulatory Networks leading to the formation of a mature leaf has precluded elucidation of the interspecific molecular dynamics in the leaf development. We per ...
... plants. However, the molecular mechanisms that give rise to leaf developmental variation are incompletely understood. The complexity of Gene Regulatory Networks leading to the formation of a mature leaf has precluded elucidation of the interspecific molecular dynamics in the leaf development. We per ...
Genetic Algorithms and the Evolution of Neural Networks for
... of approach, one of the key questions becomes how to best configure NN parameters such as topology, learning rates, training data, and other. How to choose values for these parameters is still an open question, especially since the effect these variables have on each other is not completely understo ...
... of approach, one of the key questions becomes how to best configure NN parameters such as topology, learning rates, training data, and other. How to choose values for these parameters is still an open question, especially since the effect these variables have on each other is not completely understo ...
- Philsci
... represented by the root of the tree and represents the shared ancestor of all other organisms within a particular dendrogram which have branched from that tree, making a new species. The traditional organismal phylogenies fail to preserve this level of detail of genomic phylogenies in two ways. Firs ...
... represented by the root of the tree and represents the shared ancestor of all other organisms within a particular dendrogram which have branched from that tree, making a new species. The traditional organismal phylogenies fail to preserve this level of detail of genomic phylogenies in two ways. Firs ...
AthaMap web tools for database-assisted identification of
... spacer length that is as long as the matrix of one of the two factors. In addition, even known TSSs can be selected to identify TFBSs in close vicinity to the TSSs. Owing to the large number of putative binding sites for some factors, the co-localization analysis had to be limited to 200 000 TFBSs ...
... spacer length that is as long as the matrix of one of the two factors. In addition, even known TSSs can be selected to identify TFBSs in close vicinity to the TSSs. Owing to the large number of putative binding sites for some factors, the co-localization analysis had to be limited to 200 000 TFBSs ...
Rabbit Genetics - Heavenly Hares Rabbitry
... head and around the nose and eyes. But one thing that all solids have in common is that their pattern is not interspersed with white fur (not accounting for Himalayans). Broken patterned Holland Lops can be any color of Holland Lops, except that the colored portions occur in a patched or a blanketed ...
... head and around the nose and eyes. But one thing that all solids have in common is that their pattern is not interspersed with white fur (not accounting for Himalayans). Broken patterned Holland Lops can be any color of Holland Lops, except that the colored portions occur in a patched or a blanketed ...
With the inclusion of incomplete dominance
... gene. We now know that this is an oversimplification. Although individual humans (and alldiploid organisms) can only have two alleles for a given gene, multiple alleles may exist at the population level such that many combinations of two alleles are observed. Note that when many alleles exist for th ...
... gene. We now know that this is an oversimplification. Although individual humans (and alldiploid organisms) can only have two alleles for a given gene, multiple alleles may exist at the population level such that many combinations of two alleles are observed. Note that when many alleles exist for th ...
Genome position and gene amplification | SpringerLink
... may also be distinguished by their propensity to amplify oncogenes, suggesting that the particular types of genomic instability present in a tumor are important determinants of how expression of an oncogene might be altered. Moreover, amplification is often associated with poor prognosis. Amplificat ...
... may also be distinguished by their propensity to amplify oncogenes, suggesting that the particular types of genomic instability present in a tumor are important determinants of how expression of an oncogene might be altered. Moreover, amplification is often associated with poor prognosis. Amplificat ...
PGC-1α: a key regulator of energy metabolism
... a wide variety of biological responses including adaptive thermogenesis, mitochondrial biogenesis, glucose/fatty acid metabolism, fiber type switching in skeletal muscle, and heart development (Table 1). A transcription coactivator is defined as a protein or protein complex that increases the probab ...
... a wide variety of biological responses including adaptive thermogenesis, mitochondrial biogenesis, glucose/fatty acid metabolism, fiber type switching in skeletal muscle, and heart development (Table 1). A transcription coactivator is defined as a protein or protein complex that increases the probab ...
Specification of floral organs in Arabidopsis
... et al., 2012; O’Maoileidigh et al., 2013b), suggesting a very large number of putative target genes. However, through the use of gene activation and perturbation assays, these studies also demonstrated that only a subset of the genes bound by the floral organ identity factors respond transcription ...
... et al., 2012; O’Maoileidigh et al., 2013b), suggesting a very large number of putative target genes. However, through the use of gene activation and perturbation assays, these studies also demonstrated that only a subset of the genes bound by the floral organ identity factors respond transcription ...
Genome-wide analysis of the distribution of AP2/ERF transcription
... Background: Cabbage (Brassica oleracea) is one of the most important leaf vegetables grown worldwide. The entire cabbage genome sequence and more than fifty thousand proteins have been obtained to date. However a high degree of sequence similarity and conserved genome structure remain between cabbag ...
... Background: Cabbage (Brassica oleracea) is one of the most important leaf vegetables grown worldwide. The entire cabbage genome sequence and more than fifty thousand proteins have been obtained to date. However a high degree of sequence similarity and conserved genome structure remain between cabbag ...
Text S13.
... conducted within each gene to avoid estimating translation initiation rates. The median or mean value among all genes is then reported. We calculated the ratio in average ribosome density between conserved (i.e., the encoded amino acid is invariant across six post-WGD fungal species) and unconserved ...
... conducted within each gene to avoid estimating translation initiation rates. The median or mean value among all genes is then reported. We calculated the ratio in average ribosome density between conserved (i.e., the encoded amino acid is invariant across six post-WGD fungal species) and unconserved ...
Name
... have one copy from your mother and one copy from your father. It is possible that one of these copies is associated with high cholesterol levels, while the other is associated with low cholesterol levels. For convenience, scientists have assigned a number to each pair of homologous chromosomes, orde ...
... have one copy from your mother and one copy from your father. It is possible that one of these copies is associated with high cholesterol levels, while the other is associated with low cholesterol levels. For convenience, scientists have assigned a number to each pair of homologous chromosomes, orde ...
Split hand/foot malformation genetics supports the chromosome 7
... been mutated. Nearly all studies have hypothesized a positioneffect control to explain this paradox such that the genomic rearrangements disrupt the normal expression pattern of the SHFM1 locus DLX5 gene by separating it from the required long-range-acting, cis-regulatory elements, resulting in decr ...
... been mutated. Nearly all studies have hypothesized a positioneffect control to explain this paradox such that the genomic rearrangements disrupt the normal expression pattern of the SHFM1 locus DLX5 gene by separating it from the required long-range-acting, cis-regulatory elements, resulting in decr ...
Nixon Evidence
... hypothesis). The goals here were to complete the molecular characterization of giardial and amebic fermentation enzymes and to determine the origins of the genes encoding them, when possible. A putative giardia [2Fe-2S]ferredoxin which had a hypothetical organelle-targeting sequence at its N terminu ...
... hypothesis). The goals here were to complete the molecular characterization of giardial and amebic fermentation enzymes and to determine the origins of the genes encoding them, when possible. A putative giardia [2Fe-2S]ferredoxin which had a hypothetical organelle-targeting sequence at its N terminu ...
What Size Are Your Genes?
... Size Determination of Dyes (“Genes”) After all the points have been plotted, use a ruler or a straight edge to draw the best straight line possible through the points. The line should have approximately equal numbers of points scattered on each side of the line. It is okay if the line runs through s ...
... Size Determination of Dyes (“Genes”) After all the points have been plotted, use a ruler or a straight edge to draw the best straight line possible through the points. The line should have approximately equal numbers of points scattered on each side of the line. It is okay if the line runs through s ...
Data Supplement
... between human, mouse and frog. Primers used for the Rcan1.4 promoter were: forward 5’TGGGAACTATGCCGCAAGAG-3’ and reverse 5’- GGTGGAAAAGGCGCTAAGGT-3’. Q-PCR was performed using SYBR Green kit (Qiagen) on an i-Cycler (Bio-Rad) and analyzed by the 2-∆∆C(T) method.8 Data were normalized to the input DNA ...
... between human, mouse and frog. Primers used for the Rcan1.4 promoter were: forward 5’TGGGAACTATGCCGCAAGAG-3’ and reverse 5’- GGTGGAAAAGGCGCTAAGGT-3’. Q-PCR was performed using SYBR Green kit (Qiagen) on an i-Cycler (Bio-Rad) and analyzed by the 2-∆∆C(T) method.8 Data were normalized to the input DNA ...
Identifying 3D expression domains by graph clustering
... we get an idea of the expression level of the genomic location where the insertion took place. These expression levels help identify the state of the chromatin, as ‘closed’ chromatin will result in lower expression levels compared to ‘open’ chromatin. Before the publication of the TRIP method t ...
... we get an idea of the expression level of the genomic location where the insertion took place. These expression levels help identify the state of the chromatin, as ‘closed’ chromatin will result in lower expression levels compared to ‘open’ chromatin. Before the publication of the TRIP method t ...
Murder on the development express: who killed nature/nurture
... With respect to the first point, this question was indeed the only one answerable through the techniques of classical Mendelian genetics, with its conception of genetic factors—phenotypic difference makers—as the units of inheritance. This classical gene was a hypothetical unit of function, inferred ...
... With respect to the first point, this question was indeed the only one answerable through the techniques of classical Mendelian genetics, with its conception of genetic factors—phenotypic difference makers—as the units of inheritance. This classical gene was a hypothetical unit of function, inferred ...
File
... 1. Three examples of sex-linked traits are ____________________, ___________________________, and ________________________. 2. A __________________ is a trait that is produced by genes on the X chromosome. 3. The 23rd pair of chromosomes, called the ________________________ , are different in males ...
... 1. Three examples of sex-linked traits are ____________________, ___________________________, and ________________________. 2. A __________________ is a trait that is produced by genes on the X chromosome. 3. The 23rd pair of chromosomes, called the ________________________ , are different in males ...
Molecular genetics of autosomal dominant retinitis pigmentosa
... Identification of novel polymorphisms We also found novel single nucleotide polymorphisms in some of the genes analysed (RP1, IMPDH1, NRL, and FSCN2) that caused amino acid substitutions (table 2). In particular, the RP1 gene has a significantly high frequency of missense variations with no pathogen ...
... Identification of novel polymorphisms We also found novel single nucleotide polymorphisms in some of the genes analysed (RP1, IMPDH1, NRL, and FSCN2) that caused amino acid substitutions (table 2). In particular, the RP1 gene has a significantly high frequency of missense variations with no pathogen ...
Document
... Eukaryotic Regulation • Controlling the expression of eukaryotic genes requires transcription factors. – general transcription factors are required for transcription initiation • required for proper binding of RNA polymerase to the DNA – specific transcription factors increase transcription in cert ...
... Eukaryotic Regulation • Controlling the expression of eukaryotic genes requires transcription factors. – general transcription factors are required for transcription initiation • required for proper binding of RNA polymerase to the DNA – specific transcription factors increase transcription in cert ...
Data Mining in GEO and Beyond
... Definition - a set of statistically significant differentially expressed genes and their expression directions. ...
... Definition - a set of statistically significant differentially expressed genes and their expression directions. ...
Cloning an iron-regulated metal transporter from rice
... OsIRT1, an IRT1-like metal transport protein from rice is reported. OsIRT1 has features typical of the ZIP metal transporter family, such as eight transmembrane domains and a variable region with a histidine-rich metal binding domain (Guerinot, 2000). So far, several members of this family have been ...
... OsIRT1, an IRT1-like metal transport protein from rice is reported. OsIRT1 has features typical of the ZIP metal transporter family, such as eight transmembrane domains and a variable region with a histidine-rich metal binding domain (Guerinot, 2000). So far, several members of this family have been ...
Gene expression profiling
In the field of molecular biology, gene expression profiling is the measurement of the activity (the expression) of thousands of genes at once, to create a global picture of cellular function. These profiles can, for example, distinguish between cells that are actively dividing, or show how the cells react to a particular treatment. Many experiments of this sort measure an entire genome simultaneously, that is, every gene present in a particular cell.DNA microarray technology measures the relative activity of previously identified target genes. Sequence based techniques, like serial analysis of gene expression (SAGE, SuperSAGE) are also used for gene expression profiling. SuperSAGE is especially accurate and can measure any active gene, not just a predefined set. The advent of next-generation sequencing has made sequence based expression analysis an increasingly popular, ""digital"" alternative to microarrays called RNA-Seq. However, microarrays are far more common, accounting for 17,000 PubMed articles by 2006.