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A Fitness-Independent Evolvability Measure for Evolutionary
A Fitness-Independent Evolvability Measure for Evolutionary

... Empirical studies are performed to check the evolvability of individuals in in silico evolution of oscillatory behavior using the proposed evolvability measure. Our preliminary results suggest that evolvability of the developmental system can evolve without an explicit selection pressure on evolvabi ...
Vibrio vulnificus Oysters: Pearls and Perils
Vibrio vulnificus Oysters: Pearls and Perils

... as Salmonella enterica serotype Typhi and Vibrio species) and viral pathogens (such as hepatitis A virus and caliciviruses), but V. vulnificus is the most lethal infection associated with the consumption of raw oysters. The highest density of V. vulnificus has been reported in oysters from the Gulf ...
The case for transgenerational epigenetic inheritance in humans
The case for transgenerational epigenetic inheritance in humans

... sensitive to environmental influences. Moreover, in some cases the epigenetic state at these alleles can survive across generations, termed transgenerational epigenetic inheritance. Together these findings raise the spectre of Lamarckism and epigenetics is now being touted as an explanation for some ...
Molecular Evolution of the Endosperm Starch Synthesis Pathway
Molecular Evolution of the Endosperm Starch Synthesis Pathway

... and Hofestadt 2002). Specific databases of metabolic pathways have been constructed for different organisms and are available via the Internet (e.g., for rice, www.gramene.org/ pathway). These recent advances have identified genes and their function in specific biochemical pathways and now allow for ...
Genetics and statistical association between lethal alleles and
Genetics and statistical association between lethal alleles and

... Concerning genetic load, Wallace (1970, 1981) has published a complete review on this subject. Crumpacker (1967), Gustafsson (1946), and Burnam (1993), among other authors, have revised the genetic load showing that the number of recessive mutations is quite high in different populations, either wil ...
Association of Interleukin-1 Receptor Antagonist Gene 86bp VNTR
Association of Interleukin-1 Receptor Antagonist Gene 86bp VNTR

... out method [9]. The 86 bp VNTR region of IL-1Ra gene was analyzed by polymerase chain reaction (PCR). Two oligonucleotide primers forward: 5'- CTC AGC AAC ACT CCT AT -3' and reverse: 5-' TTC CAC CAC ATG GAA C -3' based on flanking region of the IL-1Ra gene were used. PCR reaction was performed in a ...
Moving Forward at Annual Liver Life Walks
Moving Forward at Annual Liver Life Walks

... many of the same topics as Liver Matters but in ageappropriate language. Students learn that they cannot be healthy without a functioning liver and learn that liver disease can occur through IV needle usage, misuse of alcohol or other toxins, poor diet and lack of exercise, unsanitary tattooing/body ...
An In Silico Investigation Into the Discovery of Novel Cis
An In Silico Investigation Into the Discovery of Novel Cis

... Abstract: PAX3 and PAX7 are homologous paired box family members expressed during early neural and myogenic development. Assays of mRNA expression have proven conclusively that PAX3 and PAX7 transcripts are present in embryonal and alveolar rhabdomyosarcoma, neuroblastoma, Ewing’s sarcoma, and melan ...
Sphingolipids - Their Metabolic Pathways and - Limes-Institut-Bonn
Sphingolipids - Their Metabolic Pathways and - Limes-Institut-Bonn

... glycolipids, and glycosaminoglycans. Ceramide, the component of most sphingolipids, functions essentially as the anchor of lipid-bound carbohydrates in eukaryotic cells.[8±10] Ceramide itself consists of a long-chain amino alcohol, d-erythrosphingosine, the amino group of which is acylated with a fa ...
Linkage, Recombination, and the Mapping of Genes on Chromosomes
Linkage, Recombination, and the Mapping of Genes on Chromosomes

... meiotic recombination generally reflects the physical distance between them; recombination data thus make it possible to determine the distance between genes along chromosomes. • Mitotic recombination: Rarely, recombination occurs during mitosis. In multicellular organisms, mitotic recombination can ...
When the Chief Complaint Is (or Should Be) Dyspnea in
When the Chief Complaint Is (or Should Be) Dyspnea in

... COPD and its once-a-day dosing schedule. We will also consider a future prescription for pulmonary rehabilitation, because this is one of the most effective interventions for patients with COPD.25 Finally, because the patient’s arterial blood gas was normal (pH 7.45; pCO2, 38; pO2, 83), supplemental ...
DESTINY - UNC-CHAPEL HILL - CB# 7448, Morehead Planetarium
DESTINY - UNC-CHAPEL HILL - CB# 7448, Morehead Planetarium

... Immunocompetent — B cells and T cells that are fully developed and armed to fight infection. These will recirculate from blood to lymph to blood. Immunodeficiency — weakening or defects of the immune response such that an individual is unable to mount an effective immune response; may have a geneti ...
Georgidis Hartebes Genetics
Georgidis Hartebes Genetics

... Species’ geographical ranges are today so fragmented, it is often difficult to know whether remnant populations were once connected by dispersal and migration, or isolated by natural barriers. We need to know this information when action must be taken to conserve a species, for example, when individ ...
Slide 1
Slide 1

... Clotting factors: •factor concentrates •cryoprecipitate •plasma •whole blood ...
Diagnosing the severity of dry eye
Diagnosing the severity of dry eye

... specific for DED, and their use may carry a risk of overtreatment. The Ocular Surface Disease Index (OSDI) is one of the most widely used questionnaires. The OSDI and similar tools have been shown to correlate moderately well with disease severity, and to a similar degree as corneal staining (eg, r2= ...
A novel arginine substitution mutation in 1A domain and a novel 27
A novel arginine substitution mutation in 1A domain and a novel 27

... region have been reported.26–29 The proband of family B carries a novel duplication insertion of 27 nucleotides (1222ins27). This type of mutation is unique for a number of different reasons. Firstly, in-frame insertion or deletion mutations are extremely rare in keratin diseases (table 2), and this ...
The zebrafish as a model for muscular dystrophy and congenital
The zebrafish as a model for muscular dystrophy and congenital

... vestigial equivalent in human embryos, which in turn gives rise to the intervertebral discs. The dorsal and ventral halves of each chevron somite are divided by a further sheet of extracellular matrix, the horizontal myoseptum (HM), which also attaches to the notochord medially and provides a guidan ...
Canadian Heart Health Strategy and Action Plan
Canadian Heart Health Strategy and Action Plan

... Heart Healthy Canada, and its companion Action Plan. As the leading cause of death and hospitalizations among Canadians, cardiovascular disease is a huge health burden, and, at an annual cost of more than $22 billion, treating those who suffer from it is a major strain on our economy and governments ...
Complementary and Alternative Medicine Part I
Complementary and Alternative Medicine Part I

... looking for more therapeutic options than are widely available in conventional healthcare  settings. Some traditional physicians are open to using CAM without hard scientific evidence  and support its use without such evidence either as a last resort or because they had  experience with a particular ...
2 et 3 de couverture
2 et 3 de couverture

... (This et al., 2006), and the ease to transfer these data between laboratories, have become promising tools to investigate putative synonyms among grapes from distant regions (Vargas et al., 2008). In this report, we have analysed the genetic profiles of major and minor grape cultivars from Spain and ...
Myoclonic Epilepsy in Lysosomal Storage Disorders
Myoclonic Epilepsy in Lysosomal Storage Disorders

... The disease has been classically classified in three major clinical variants based on the presence and progression of central nervous system involvement. Type 1 GD (MIM# 230800), the most common phenotype, is characterized by enlargement and dysfunction of liver and spleen, displacement of normal bo ...
Oral Candidiasis
Oral Candidiasis

... Though C. albicans is the most common cause of yeast infections, the non-albicans Candida species9 are increasing in prevalence. C. glabrata is the second most common species in candidiasis or candidemia10, and the number one non-albicans Candida spp. in blood stream infections (18). In patients you ...
Tropical Disease Research - World Health Organization
Tropical Disease Research - World Health Organization

... Godal, a key person in the shaping of the new WHO – was asked on ‘day one’ to start organizing a top priority of the new WHO, the Roll Back Malaria Cabinet Project. This left to me the honour of becoming the new Director of TDR and the responsibility of guiding this most successful Special Programme ...
Ingestion of bacterially expressed dsRNAs can produce specific and
Ingestion of bacterially expressed dsRNAs can produce specific and

... LT and AF, unpublished). The dsRNA isolated from HT115(DE3) cells was also biologically active for RNAi; i.e. injection of this dsRNA into N2 worms produced a twitching phenotype (data not shown). ...
Concordance trees, concordance factors, and the exploration of
Concordance trees, concordance factors, and the exploration of

... has a known population history. At best one has molecular data for a number of loci for a set of individuals representative of the taxa under study. If we are prepared to make some assumptions about the nature of populations and genetic processes, these data contain information on the history of the ...
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Public health genomics

Public Health Genomics is the use of genomics information to benefit public health. This is visualized as more effective personalized preventive care and disease treatments with better specificity, targeted to the genetic makeup of each patient. According to the CDC, Public Health genomics is an emerging field of study that assesses the impact of genes and their interaction with behavior, diet and the environment on the population’s health.This field of public health genomics is less than a decade old. A number of think tanks, universities, and governments (including the U.S., UK, and Australia) have started public health genomics projects. Research on the human genome is generating new knowledge that is changing public health programs and policies. Advances in genomic sciences are increasingly being used to improve health, prevent disease, educate and train the public health workforce, other healthcare providers, and citizens.
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