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2001_butterfield_THE SUGARCANE GENOME
2001_butterfield_THE SUGARCANE GENOME

... not be serious under tropical growing conditions, loss of desirable S. spontaneum traits for hardiness, tillering and ratooning ability could affect the long-term success of breeding programmes in subtropical areas such as South Africa. Selection may to some extent mitigate the effects of chromosome ...
Alternative Splicing
Alternative Splicing

... Alternative splicing plays an important role in regulating gene expression. In the last decade it has been shown that alternative splicing determines binding properties, intracellular localization, enzymatic activity, protein stability and posttranslational modifications of a large number of protein ...
GATA factor function in heart development
GATA factor function in heart development

... pnr gene affects heart development. (A-D) Expression of pnr results in overexpression of a D-mef2 heart enhancer and cardiac hyperplasia. Stage 11 (A,B) and 16 (C,D) embryos stained for lacZ expression under the control of a D-mef2 cardial cell enhancer are shown. (A,C) WT, wild-type embryos; (B,D) ...
Resistance to cephalosporins and carbapenems in Gram
Resistance to cephalosporins and carbapenems in Gram

... to extended substrate specificity. These mutations affect the recognition of substrates and the rates of formation and hydrolysis of the acyl–enzyme complex. There is sufficient evidence that class A ␤-lactamases perform several conformational changes induced by substrate binding and substrate reactio ...
SNP - Asia University, Taiwan
SNP - Asia University, Taiwan

... synonymous polymorphisms (change the codon but not the amino acid) Nonreplacement polymorphisms include both synonymous and noncoding polymorphisms, but, could still affect gene function by having an effect on transcriptional or translational regulation, splicing, or RNA stability. This type of poly ...
The sequence of a gene encoding convicilin from pea
The sequence of a gene encoding convicilin from pea

... legumin genes, but is not directly homologous with them. Comparison of this sequence with the 'inserted' sequence in soya-bean (Glycine max) conglycinin (a homologous vicilin-type protein) suggests that the two insertions were independent events. The 5' flanking sequence of the gene contains several ...
Construction of nanA mutants
Construction of nanA mutants

... and transformants were selected on blood agar plates containing 200 µg/ml Kan. Selected transformants were screened for SmS. The correct junction fragments were verified by PCR with primers internal to the Janus cassette and the two outer primers outside of the nanA gene. Construction of in-frame, u ...
Construction of a pBAD24 Vector Containing σ32 : Restoration of
Construction of a pBAD24 Vector Containing σ32 : Restoration of

Dynamic Changes in Aromatic Hydrocarbon Associated Catabolic
Dynamic Changes in Aromatic Hydrocarbon Associated Catabolic

... Results from this work also indicate that more bcr copies were detected overall within the benzoate microcosms compared to the toluene microcosms. This could reflect the differences in the types of microorganisms present in the two inocula. For example microorganisms present in the river sediment us ...
Molecular genetics of Rett syndrome and clinical
Molecular genetics of Rett syndrome and clinical

... chromosomal regions is dispensable since, if binding of MeCP2 were indeed essential in every methylated region, the consequence of its loss would be equivalent to loss of methylation. Yet this is not the case: extensive demethylation of the mouse genome by mutation of DNA methyltransferase 1 (Dnmt1) ...
Genetic Testing for Hereditary Breast and/or Ovarian Cancer
Genetic Testing for Hereditary Breast and/or Ovarian Cancer

... Germline mutations in the BRCA1 and BRCA2 genes are responsible for cancer susceptibility in the majority of HBOC families, especially if ovarian cancer or male breast cancer are features. However, in site-specific breast cancer, BRCA mutations are responsible for only a proportion of affected famil ...
Supplementary Data File Supplementary Figures Figure S1
Supplementary Data File Supplementary Figures Figure S1

... Figure S1. Hypothetical example of variability count distributions for a pathway and a reference. A. The reference distribution corresponds to a hypothetical data set with 10,000 genes where 2,500 genes are in the low variability category, 5000 in the medium and 2500 in the high variability category ...
Transgenic Plastids in Basic Research and Plant Biotechnology
Transgenic Plastids in Basic Research and Plant Biotechnology

... to effective inhibition of plastid protein biosynthesis by spectinomycin (an aminoglycoside antibiotic speci®cally blocking translation on prokaryotic-type 70 S ribosomes). A successfully transformed chloroplast expresses the spectinomycin-resistance gene, aadA, thus allowing for continued cell and ...
Genetics PP notes 2015
Genetics PP notes 2015

... T F 1. Certain acquired characteristics, such as mechanical or mathematical skill, may be inherited. T F 2. Identical twins are always of the same sex. T F 3. Fraternal twins are more closely related to each other than to other children in a family. T F 4. The father determines the sex of a child. T ...
MOLECULAR PROFILING OF RICE (Oryza sativa L
MOLECULAR PROFILING OF RICE (Oryza sativa L

Specification of unique neuronal sub-types by integration of positional and temporal cues
Specification of unique neuronal sub-types by integration of positional and temporal cues

Two-Component System of Mycobacterium Tuberculosis
Two-Component System of Mycobacterium Tuberculosis

... Under phosphate-starvation-induction conditions, the Response Regulator (RR) PhoP, and the histidine protein kinase (HK) PhoR, are involved in the induction of Pho-regulon genes including the phoPR operon and genes encoding the major vegetative alkaline phosphatases, phoA and phoB. The PhoP protein ...
X - Bioinformatics.ca
X - Bioinformatics.ca

... A reliable and precise classification of tumors is essential for successful diagnosis and treatment of cancer. Current methods for classifying human malignancies rely on a variety of morphological, clinical, and molecular variables. In spite of recent progress, there are still uncertainties in diagn ...
15_Lecture_Presentation
15_Lecture_Presentation

PDF
PDF

... constituting a new fly model of human neurodegenerative disease. ...
Document
Document

... control of multiple gene pairs • For example: Human Skin Color • Alleles are… Dark and light • At least… three genes control the color of your skin • The phenotype is a result of… the cumulative effects of the dominant genes • Human skin color exists… as a gradient ...
Unit 4 - Purdue Agriculture
Unit 4 - Purdue Agriculture

... inheritance in pea plants. He observed that many traits, from height to flower color, seemed to be controlled by these factors. In 1903, researcher William Sutton made the connection between Mendel’s factors and chromosomes—microscopic structures in the cell nucleus that carry genetic material. The ...
A gene complex controlling segmentation in Drosophila
A gene complex controlling segmentation in Drosophila

... hemizygotes, suggesting that BX-C genes control mesodermal as well as ectodermal tissues. Gonadal examination of Uab 4 genotypes was prompted by the report of gonadal defects in homozygotes for certain Uab-like mutants of the homologous 'E-Iocus' complex of Bombyx (see review by Tazima 12). Segment ...
PDF
PDF

... The expression of snail in the hydroid Podocoryne, and the behaviour of cells containing it, have both interesting similarities and differences when compared to the situation in Acropora. During Podocoryne embryonic development snail mRNA, which is provided maternally, is present in all developmenta ...
Peromyscus polionotus (the monogamous mouse)
Peromyscus polionotus (the monogamous mouse)

... available for research with federal funds • Growth on mouse feeders makes them unsuitable for use as therapeutics • The indications being considered are, among others, cardiovascular and neurological ...
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Nutriepigenomics

Nutriepigenomics is the study of food nutrients and their effects on human health through epigenetic modifications. There is now considerable evidence that nutritional imbalances during gestation and lactation are linked to non-communicable diseases, such as obesity, cardiovascular disease, diabetes, hypertension, and cancer. If metabolic disturbances occur during critical time windows of development, the resulting epigenetic alterations can lead to permanent changes in tissue and organ structure or function and predispose individuals to disease.
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