Understanding the basis of auriculocondylar syndrome: Insights
... OAVS: oculoauriculovertebral spectrum. Highly heterogeneous disorder, most likely multifactorial and no genetic mechanism has yet been clearly established. b Isolated Pierre Robin sequence (PRS) is likely to be genetically heterogeneous. The etiology of most cases is largely unknown, except for case ...
... OAVS: oculoauriculovertebral spectrum. Highly heterogeneous disorder, most likely multifactorial and no genetic mechanism has yet been clearly established. b Isolated Pierre Robin sequence (PRS) is likely to be genetically heterogeneous. The etiology of most cases is largely unknown, except for case ...
The mitochondrial genome of the soybean cyst nematode
... (55%), Onchocerca volvulus (54%), and R. similis (53%) have comparable levels. By comparison, enoplean nematodes tend to have slightly lower T-contents, with a range of 27% (Trichinella spiralis) to 44% (Agamermis sp.). A comparison with other pseudocoelomates (from the phyla Acanthocephala and Roti ...
... (55%), Onchocerca volvulus (54%), and R. similis (53%) have comparable levels. By comparison, enoplean nematodes tend to have slightly lower T-contents, with a range of 27% (Trichinella spiralis) to 44% (Agamermis sp.). A comparison with other pseudocoelomates (from the phyla Acanthocephala and Roti ...
transposon
... on the phenotype, but could constitute “selfish DNA,” concerned only with their own propagation. ...
... on the phenotype, but could constitute “selfish DNA,” concerned only with their own propagation. ...
6 Gene Interaction
... Answer: You are told that the cross of two erminette fowls results in 22 erminette, 14 black, and 12 pure white. Two facts are important: (1) the parents consist of only one phenotype, yet the offspring have three phenotypes, and (2) the progeny appear in an approximate ratio of 1:2:1. These facts s ...
... Answer: You are told that the cross of two erminette fowls results in 22 erminette, 14 black, and 12 pure white. Two facts are important: (1) the parents consist of only one phenotype, yet the offspring have three phenotypes, and (2) the progeny appear in an approximate ratio of 1:2:1. These facts s ...
Case Report Ain`t No Sunshine When She`s Gone
... with biochemical abnormalities and a normal phenotype, the most likely diagnosis is PHP type 1b, a methylation defect of the maternal GNAS1 gene. This is supported by the fact that a mutation in GNAS1 could not be demonstrated. However, type 2 PHP, where the problem originates from the signaling cas ...
... with biochemical abnormalities and a normal phenotype, the most likely diagnosis is PHP type 1b, a methylation defect of the maternal GNAS1 gene. This is supported by the fact that a mutation in GNAS1 could not be demonstrated. However, type 2 PHP, where the problem originates from the signaling cas ...
The fibrodysplasia ossificans progressiva R206H
... R206H) into alk8–/– zebrafish embryos induced a strongly ventralized phenotype at 1 day after fertilization (Figure 3, D–F), indicating that the FOP ACVR1 mutation induces hyperactivity of BMP signaling in the zebrafish embryo. Compared with the alk8 mutants rescued with wild-type ACVR1, R206H ACVR1 ...
... R206H) into alk8–/– zebrafish embryos induced a strongly ventralized phenotype at 1 day after fertilization (Figure 3, D–F), indicating that the FOP ACVR1 mutation induces hyperactivity of BMP signaling in the zebrafish embryo. Compared with the alk8 mutants rescued with wild-type ACVR1, R206H ACVR1 ...
Replication timing and transcriptional control: beyond
... the late-replicating allele at random. Notably, it is almost always the early-replicating allele that is initially selected to undergo rearrangement, suggesting that replication timing is an early developmental marker for allelic exclusion in the immune system. Inactivation of the X chromosome is cu ...
... the late-replicating allele at random. Notably, it is almost always the early-replicating allele that is initially selected to undergo rearrangement, suggesting that replication timing is an early developmental marker for allelic exclusion in the immune system. Inactivation of the X chromosome is cu ...
Running Head: THE GENDER ASSOCIATION OF DYSLEXIA THE
... the age range of the subjects could also be considered too big. All children develop differently at a different pace depending on a multitude of things. Therefore, the capability of the children to do each task can vary due to this factor versus the fact that some children are dyslexic. This is main ...
... the age range of the subjects could also be considered too big. All children develop differently at a different pace depending on a multitude of things. Therefore, the capability of the children to do each task can vary due to this factor versus the fact that some children are dyslexic. This is main ...
The relationship between higher‑order chromatin structure and
... So where do open chromatin fibres originate? Support for the idea that regions of ‘open’ chromatin fibres correspond to transcriptionally active genes came from sedimentation analysis of the chicken β‑globin locus. When active, i.e. in erythrocytes, chromatin from this locus sediments more slowly th ...
... So where do open chromatin fibres originate? Support for the idea that regions of ‘open’ chromatin fibres correspond to transcriptionally active genes came from sedimentation analysis of the chicken β‑globin locus. When active, i.e. in erythrocytes, chromatin from this locus sediments more slowly th ...
letters - Centre for Social Evolution
... significantly lower than the former (P 5 0.016, one-tailed Fisher’s exact test) suggesting that stronger positive selection operated during the early formation of the csd gene than during lineage-specific divergence. The fem gene—the progenitor of csd—is under purifying selection, showing an excess ...
... significantly lower than the former (P 5 0.016, one-tailed Fisher’s exact test) suggesting that stronger positive selection operated during the early formation of the csd gene than during lineage-specific divergence. The fem gene—the progenitor of csd—is under purifying selection, showing an excess ...
Role of Genes - Native American Cancer Research
... damage that is passed on from the first body (somatic) cell as it divides into additional cells It gives the cells harboring the mutation an advantage to outgrow other cells For example in lung cancer the carcinogens in cigarette smoke may cause damage in several genes Bemis, UMN-Duluth, Burhansstip ...
... damage that is passed on from the first body (somatic) cell as it divides into additional cells It gives the cells harboring the mutation an advantage to outgrow other cells For example in lung cancer the carcinogens in cigarette smoke may cause damage in several genes Bemis, UMN-Duluth, Burhansstip ...
transposon
... on the phenotype, but could constitute “selfish DNA,” concerned only with their own propagation. ...
... on the phenotype, but could constitute “selfish DNA,” concerned only with their own propagation. ...
Activation of the Interleukin-3 Gene by Chromosome
... IL-3 gene. The two chromosome 5 breakpoints were separated by less than 500 bp. The genomic structure in Cases 1 and 2 suggested that a normal IL-3 gene product was over-expressed as a result of the altered promotor structure. This would predict that the IL-3 gene on the translocated chromosome was ...
... IL-3 gene. The two chromosome 5 breakpoints were separated by less than 500 bp. The genomic structure in Cases 1 and 2 suggested that a normal IL-3 gene product was over-expressed as a result of the altered promotor structure. This would predict that the IL-3 gene on the translocated chromosome was ...
Ubiquitin-Like Protein 5 Positively Regulates Chaperone Gene
... GATC-39) and F46F11.2AS (59-GAAATGAATTCTGATGAAT CATTGG-39) and the C. briggsae cDNA was amplified using the same UBL-5.brig.1S and UBL-5.brig.2AS primers described above. The inserts were ligated into the pPD129.36 plasmid. The screen for genes whose inactivation by RNAi interferes with hsp-60Tgfp e ...
... GATC-39) and F46F11.2AS (59-GAAATGAATTCTGATGAAT CATTGG-39) and the C. briggsae cDNA was amplified using the same UBL-5.brig.1S and UBL-5.brig.2AS primers described above. The inserts were ligated into the pPD129.36 plasmid. The screen for genes whose inactivation by RNAi interferes with hsp-60Tgfp e ...
Achondroplasia: pathogenesis and implications for future treatment
... Research on the mutation in Fibroblast Growth Factor Receptor 3 (FGFR3) that causes achondroplasia suggests that disease results from increased signal transduction from the mutant receptor. Thus, current therapeutic strategies have focused on reducing signals emanating from FGFR3. First-generation t ...
... Research on the mutation in Fibroblast Growth Factor Receptor 3 (FGFR3) that causes achondroplasia suggests that disease results from increased signal transduction from the mutant receptor. Thus, current therapeutic strategies have focused on reducing signals emanating from FGFR3. First-generation t ...
Candidate gene scan for Single Nucleotide Polymorphisms involved
... transcription, translation and other cellular mechanics. To date, both the genetic and even ...
... transcription, translation and other cellular mechanics. To date, both the genetic and even ...
Disruption and aberrant expression of HMGA2 as a
... human mesenchymal tumors, resulting in fusion to diverse partner genes. In lipomas, HMGA2 has been shown to fuse to LPP at 3q27–q28, a gene encoding an LIM domain-containing protein;8,15 to LHFP at 13q12, the function of which is still unknown;16 to the G-protein-coupled receptor RDC1 at 2q35– 3717 ...
... human mesenchymal tumors, resulting in fusion to diverse partner genes. In lipomas, HMGA2 has been shown to fuse to LPP at 3q27–q28, a gene encoding an LIM domain-containing protein;8,15 to LHFP at 13q12, the function of which is still unknown;16 to the G-protein-coupled receptor RDC1 at 2q35– 3717 ...
... BCR/ABL the crucial event lies on der(22), id est 5’ BCR - 3’ ABL hybrid gene is the crucial one, while ABL/BCR may or may not be expressed; breakpoint in ABL is variable over a region of 200 kb, often between the two alternative exons 1b and 1a, sometimes 5’ of 1b or 3’ of 1a, but always 5’ of exon ...
Vitamin D the Sunshine vitamin - Dr
... Sockeye salmon has beneficial amounts of vitamin B complex, vitamin E, magnesium, phosphorus, selenium and zinc. It is also one of the few protein sources with alkaline rather than acidic properties. The good fats in the salmon provide numerous health Sockeye salmon contains two antioxidants: vitami ...
... Sockeye salmon has beneficial amounts of vitamin B complex, vitamin E, magnesium, phosphorus, selenium and zinc. It is also one of the few protein sources with alkaline rather than acidic properties. The good fats in the salmon provide numerous health Sockeye salmon contains two antioxidants: vitami ...
Characterization of lysine decarboxylase
... and the other representative of PT14b strains (E-1217). The LDC phenotype of both strains was restored following transformation with pUC18-cadBA, pUC18-cadC and pUC19-cadC. However, the introduction of pUC19-cadBA did not restore the LDC phenotype (Table 2). These results suggest that (1) the LDC ph ...
... and the other representative of PT14b strains (E-1217). The LDC phenotype of both strains was restored following transformation with pUC18-cadBA, pUC18-cadC and pUC19-cadC. However, the introduction of pUC19-cadBA did not restore the LDC phenotype (Table 2). These results suggest that (1) the LDC ph ...
Cooperative Effects of Bacterial Mutations Affecting A N Gene
... these phages carry mutations which render them either partially or fully N-independent. Thus, Abyp, Anin, and Aimm434byp all plate well on the Supernus strains at 32”. We next will discuss the effect of Supernus on phage growth at 42”. As shown in Table 4, the nusA-1 host significantly reduces A gro ...
... these phages carry mutations which render them either partially or fully N-independent. Thus, Abyp, Anin, and Aimm434byp all plate well on the Supernus strains at 32”. We next will discuss the effect of Supernus on phage growth at 42”. As shown in Table 4, the nusA-1 host significantly reduces A gro ...
The Arabidopsis Protein SHI Represses
... their function as suppressors of GA signaling in these species have been supported by mutant analysis. A barley homolog of the SPY gene, HvSPY, has been cloned recently, and the gene product is shown to be able to specifically inhibit GA-induced expression of barley ␣-amylase (Robertson et al., 1998 ...
... their function as suppressors of GA signaling in these species have been supported by mutant analysis. A barley homolog of the SPY gene, HvSPY, has been cloned recently, and the gene product is shown to be able to specifically inhibit GA-induced expression of barley ␣-amylase (Robertson et al., 1998 ...
Number 48, 2001 35
... Crosses heterozygous for large segmental duplications are characteristically barren, i.e., the perithecia produce very few viable ascospores (Raju and Perkins 1978 Can. J. Genet. Cytol. 20:41-59). In contrast, crosses involving strains containing balanced rearrangements (i.e., without duplications) ...
... Crosses heterozygous for large segmental duplications are characteristically barren, i.e., the perithecia produce very few viable ascospores (Raju and Perkins 1978 Can. J. Genet. Cytol. 20:41-59). In contrast, crosses involving strains containing balanced rearrangements (i.e., without duplications) ...