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What Are Lethal Whites?
What Are Lethal Whites?

... merle gene, and will produce a pup that is mostly white, and usually deaf and/or blind. This is the "Lethal White" Aussie. Lethal Whites can only result from a merle to merle breeding, but not every puppy in the litter is a homozygous (MM) white. Statistics indicate that approximately 25% of the lit ...
Severe congenital neutropenia (SCN) and cyclic neutropenia
Severe congenital neutropenia (SCN) and cyclic neutropenia

... or AML; otherwise, the disorder is clinically indistinguishable from ELA2-related SCN. The HAX1 gene consists of seven exons and encodes a 279 amino acid protein which plays a role in neutrophil-specific apoptosis. WAS: X-linked congenital neutropenia (XLN) is caused by mutations in WAS that result ...
Molecular characterization of dioxygenases from polycyclic aromatic
Molecular characterization of dioxygenases from polycyclic aromatic

... [Fe2 ^S2 ] Rieske center and the mononuclear iron binding domain, which are involved in the consecutive electron transfer to the dioxygen molecule [6]. Both K and L subunits are necessary for function and in determining the substrate speci¢city of the dioxygenase [7]. Most information about metaboli ...
Genetics - Denton ISD
Genetics - Denton ISD

... h. Capital letters are used to show which is the dominant allele (copy of the gene) 1. i.e. T = the tall allele (dominant) ...
Fibrillin microfibrils: Connective tissue pathways that regulate shape
Fibrillin microfibrils: Connective tissue pathways that regulate shape

... Fibrillins are large modular extracellular matrix proteins that form the backbone structure of "microfibrils." Fibrillin microfibrils are ubiquitous in the connective tissue space. The importance of fibrillin microfibrils to specific connective tissues is demonstrated by the phenotypic features of t ...
Life: The Science of Biology, 8e
Life: The Science of Biology, 8e

... genes for unusual metabolic functions such as breaking down hydrocarbons. Fertility factors (F factors) have genes needed for conjugation; F factor can be transferred during conjugation. ...
Uniparental Disomy (UPD)
Uniparental Disomy (UPD)

... of a mutation-carrying gene from a single parent. This has been documented for several genetic conditions.2 The chance that UPD exists when a trisomy, mosaicism (partial trisomy), or balanced translocation are observed in prenatal diagnosis ranges from less than 1% to approximately 66%. Due to the b ...
S010
S010

... microRNA precursor hairpin has the potential to produce two different mature microRNAs. We have investigated the evolutionary and functional relationships between the multiple products of microRNA transcripts. We find the most common mechanism for the formation of multi-product transcripts is de nov ...
A type III-like restriction endonuclease functions as a major barrier to
A type III-like restriction endonuclease functions as a major barrier to

... cleavage occurs on collision of two translocating restriction complexes away from the recognition site (11). The type II restriction system is well known by all scientists who perform molecular biology experiments (12, 13). It consists of a site-specific methylase and a site-specific restriction endon ...
Word - NIEHS SNPs Program - University of Washington
Word - NIEHS SNPs Program - University of Washington

... As a launching point, we will begin our search at the NIEHS SNPs resource. This can be accessed at http://egp.gs.washington.edu/ The NIEHS SNPs Program at the University of Washington is part of the EGP. The EGP is a multi-disciplinary effort focused on exploring the relationships between environmen ...
Supporting Information Notes S4 Molecular constraints of Pi
Supporting Information Notes S4 Molecular constraints of Pi

Is HP1 an RNA detector that functions both in repression and
Is HP1 an RNA detector that functions both in repression and

... RNA double strands specify targeting of a separate class of HP1 repressing complexes to heterochromatic regions? If sense RNA strands are capable of recruiting HP1 to euchromatic sites, why is recruitment largely restricted to sites of intense transcriptional activity? Does HP1 affect different aspe ...
Benjamin Schlegel
Benjamin Schlegel

Evolution of Immunoglobulin Kappa Chain Variable Region
Evolution of Immunoglobulin Kappa Chain Variable Region

... a sequence similarity of 95%–100%, and this duplication has not been found in the chimpanzee, gorilla, or orangutan (Ermert et al. 1995). From information on the overall sequence divergence between the two sets of duplicate genes (;1%), Schäble and Zachau (1993) suggested that the duplication occur ...
Ch 8 Workbook Answer Key
Ch 8 Workbook Answer Key

... When the S bacteria were killed, they did not cause the mice to die. However, when killed S bacteria were mixed with live R bacteria, the mice died and Griffith found live S bacteria in their blood. This led Griffith to conclude that there was a transforming principle that could change R bacteria in ...
Sequence analysis of three mitochondrial DNA molecules reveals
Sequence analysis of three mitochondrial DNA molecules reveals

... Saccharomyces castellii and Saccharomyces servazzii, consisting of 25 753 and 30 782 bp, respectively, were analysed and compared to Saccharomyces cerevisiae mtDNA. While some of the traits are very similar among Saccharomyces yeasts, others have highly diverged. The two mtDNAs are much more compact ...
The effect of DNA phase structure on DNA walks
The effect of DNA phase structure on DNA walks

... ratio than the whole genome (see Gardiner [3] for review). For the yeast genome the correlation between “coding density” and (G + C)/(A + T ) ratio has been shown by Sharp and Lloyd [11]). During transcription each strand of a DNA sequence can be read only in one direction in natural systems. The RN ...
Activation of Silent Genes by Transposons Tn5 and TnlO
Activation of Silent Genes by Transposons Tn5 and TnlO

... 4 has a T n IO(HH104) element (increased transposase) on an F' plasmid. The most frequent hisD activation (line 5 ) was seen in a strain carryingthe hyperactive element T n lO(HHlO4) ona highcopy plasmid. A mutant of T n 5 with an amber mutation in its transposase gene was made by D. BIEK(BIEK and R ...
P generation
P generation

... genetic and environmental factors collectively influence phenotype. ...
Marine integrons containing novel integrase genes
Marine integrons containing novel integrase genes

... The ISME Journal (2011) 5, 1162–1177; doi:10.1038/ismej.2010.208; published online 20 January 2011 Subject Category: integrated genomics and post-genomics approaches in microbial ecology Keywords: integrons; gene cassettes; metagenome; polluted marine sediment ...
Study Guide
Study Guide

... Quiz yourself  Cover the words/ definitions with a piece of paper. Focus on starred items! Answer out-loud. When you can confidently answer yourself, ask a friend or home supporter to give you the word and you give the definition in the standard form, and then, explain it in your own words. ...
Three Allele Combinations Associated with
Three Allele Combinations Associated with

... Investigation of polygenic human diseases, which arise from the combined contribution of multiple independently acting and/or interacting polymorphic genes, remains a great challenge [1-3]. A common constituent of the complexity that underlies the susceptibility to polygenic diseases is heterogeneit ...
Ch6Sec3 Reinforce Mendel Hered
Ch6Sec3 Reinforce Mendel Hered

Direct Deletion Analysis in Two Duchenne Muscular Dystrophy
Direct Deletion Analysis in Two Duchenne Muscular Dystrophy

... sequences, which are located in a distal part of the gene (3’ from intron 44) that affects some brain-specific dystrophin isoforms (Dp 140, Dp 71), may be related to the cognitive impairment (Meizard et al., 1998). Since both of our patients showed mental retardation, we sought then to determine whe ...
manual - Cedar Crest College
manual - Cedar Crest College

... 4.  The  treatment  of  nonrandom  mating  has  been  extended.    In  previous  versions,  nonrandom   mating  was  simulated  by  first  randomly  choosing  a  pair  of  individuals  to  mate,  then  determining  if   the  mating  was ...
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Nutriepigenomics

Nutriepigenomics is the study of food nutrients and their effects on human health through epigenetic modifications. There is now considerable evidence that nutritional imbalances during gestation and lactation are linked to non-communicable diseases, such as obesity, cardiovascular disease, diabetes, hypertension, and cancer. If metabolic disturbances occur during critical time windows of development, the resulting epigenetic alterations can lead to permanent changes in tissue and organ structure or function and predispose individuals to disease.
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