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Nucleotide sequence and taxonomic value of the
Nucleotide sequence and taxonomic value of the

... 'distance' between pairs of species from DNA sequences which are then utilized by the distance matrix programs FITCH and KITSCH. Sequences were first aligned with the multiple alignment program CLUSTAL (Higgins & Sharp, 1988) so that they contained the same number of characters including padding cha ...
Wnt Signaling and an APC-Related Gene Specify Endoderm in
Wnt Signaling and an APC-Related Gene Specify Endoderm in

... (Table 1); these embryos have partial body morphogenesis, in contrast to wrm-1(RNAi) embryos that have no body morphogenesis (Figure 3 and data not shown). Laser ablation experiments similar to those described above confirmed that the E blastomere in 2/9 apr1(RNAi) embryos adopts an MS-like fate: E ...
Mineral Catalysis and Prebiotic Synthesis: Montmorillonite
Mineral Catalysis and Prebiotic Synthesis: Montmorillonite

... was based only on RNA rather than the DNA and protein polymers essential for life today. This hypothesis has the advantage of only requiring prebiotic synthesis of one polymer (RNA) rather than two (DNA and protein). While the debate between a metabolism-first and geneticfirst origin of life continu ...
ELEM_CouvC_V1n3 copy
ELEM_CouvC_V1n3 copy

... was based only on RNA rather than the DNA and protein polymers essential for life today. This hypothesis has the advantage of only requiring prebiotic synthesis of one polymer (RNA) rather than two (DNA and protein). While the debate between a metabolism-first and geneticfirst origin of life continu ...
Ribosomal Protein RPL27a Promotes Female Gametophyte
Ribosomal Protein RPL27a Promotes Female Gametophyte

... 2012; McCann and Baserga, 2013; Terzian and Box, 2013). Currently it is not known how ribosomal proteins modulate development. Potentially specific developmental phenotypes in ribosomal protein mutants are an outcome of ribosome haploinsufficiency and reduced global protein synthesis or reduced tran ...
Growth medium composition-determined regulatory mechanisms
Growth medium composition-determined regulatory mechanisms

... Transcriptional activation from the pheBA and catBCA promoters is regulated by CatR and the catechol degradation pathway intermediate cis,cis-muconate. Here it is shown that physiological control mechanisms are superimposed on this regulatory system. Transcriptional activation from the pheBA and cat ...
IGEM_presentation
IGEM_presentation

... ai is rate of production of i in absence of repression, bi is the binding constant of component I to its activator, ei is the inverse rate of breakdown of component i. L relates to LexA, R to RecA, R* to RecA* and S to ssDNA Ki is the binding constant of component i to the LexA gene. Cs is the conce ...
Full-Text PDF
Full-Text PDF

... “coevolutionary” theory in which amino acids and (very small) peptides as well as small RNAs existed together and where their separate abilities not only reinforced each other’s survival, but allowed life to more quickly climb the ladder of complexity. Essential for our approach is the following: St ...
Powerpoint Presentation
Powerpoint Presentation

... •The concentration of X-gal is constant at 0.5M within the cell at all times. •The concentration of X-gal is sufficiently large to have the rate of change of indigo be equal to Vmax. •Vmax is equal to Kcat multiplied by the concentration of β-galactosidase. •The concentration of β-galactosidase is e ...
[Full text/PDF]
[Full text/PDF]

... interpretation methods [14], the use of odds ratios [15], log-linear methods [16], generalized linear models [17], and permutation ...
Darwin`s big problem and Mendelian genetics
Darwin`s big problem and Mendelian genetics

... an individual’s combination of alleles is its genotype − a pea plant’s genotype for seed color might be YY, or Yy, or yy and the observable characteristics that it displays are called its phenotype − such as having yellow seeds or green seeds − in most cases, the phenotype is influenced not only by ...
Phytic Acid and Inorganic Phosphate Composition in Soybean Lines
Phytic Acid and Inorganic Phosphate Composition in Soybean Lines

... inositol polyphosphate kinase, with lower inositol phosphates also capable of being substrates in addition to inositol-pentakisphosphate (Caddick et al., 2008; StevensonPaulik et al., 2005; Sun et al., 2007; Sweetman et al., 2006). Soybean is derived from ancient genome duplication events, and the e ...
A set reduction and pattern matching problem motivated by Allele
A set reduction and pattern matching problem motivated by Allele

... region by a DNA polymerase which extends the primer sequence and creates two copies of the flanked region. This process is repeated many times causing exponential amplification of the sequence and ensuring it is present in detectable levels (Fig. 1). Allelic variants—different sets of alleles in an ...
PHI-Canto video tutorial text - PHI-base
PHI-Canto video tutorial text - PHI-base

... And we move onto Step5c adding an annotation term. # In this case to the curation type ‘PHI phenotype’. # I am looking for ‘unaffected pathogenicity’ in the search box # which is one of 9 upper level PHI phenotype outcome terms used in the preliminary annotation. Subsequent additional PHI phenotype ...
Datasheet - Santa Cruz Biotechnology
Datasheet - Santa Cruz Biotechnology

... BACKGROUND ...
A Conserved Molecular Framework for Compound Leaf Development
A Conserved Molecular Framework for Compound Leaf Development

... In A. caerula, AcNAM and AcCUC3 are expressed at the boundaries between leaf primordia (lp) and the meristem (m) during the formation of the rosette leaves (A, B) and after bolting (C). In the floral meristem (fm), AcNAM marks the boundary of the numerous stamen primordia (stp, D). In the vegetative ...
(mmg) operon of Bacillus
(mmg) operon of Bacillus

... various industries. Hence this organism is extensively studied. The genome of this bacterium has around 4000 protein coding sequences, which include 87% of the genome sequence. Because of its ability to use different carbohydrates, the glycolytic pathway along with the TCA cycle is utilized in this ...
1 - life.illinois.edu
1 - life.illinois.edu

... are resistant to both K and P1 restriction systems. b. In a second experiment, they labeled lambda DNA of phage growing in E. coli K (P1) with 32P so that the newly synthesized DNA in the phage was radioactive. They then infected E. coli K cells with the radioactive phage in medium containing nonrad ...
Assaying … promoter activity
Assaying … promoter activity

... …the plasmid integrated into the genome by homologous recombination with the nimB and ORF5468 gene. We tested the stability of the integrated plasmid via a true breeding experiment. In this experiment, recombinant cells were grown at the non-permissive temperature in the absence of antibiotic select ...
Selecting an Ontology for Biomedical Text Mining He Tan, Patrick Lambrix Abstract
Selecting an Ontology for Biomedical Text Mining He Tan, Patrick Lambrix Abstract

... access to text, natural language processing, and information integration. Developers of text mining applications often look for appropriate ontologies that can be integrated into their systems, rather than develop new ontologies from scratch. The choice of ontology may, however, have a major impact ...
Genetic Basis for Osmosensitivity and Genetic Instability of the Wine
Genetic Basis for Osmosensitivity and Genetic Instability of the Wine

... using 2 µL cDNA as template for both genes of interest. IPP1 was used as a control gene, as this gene is not affected by osmotic stress (Rep et al. 1999). IPP1 was also expressed at the same levels in ST and VIN7. Samples were cycled 40 times between 95°C for 15 sec and 57°C for 1 min. To cal‑ culat ...
PDF
PDF

... XRnf12C share 89% identity with each other, and contain similar repetitive sequences of heptamer peptide of distinct sizes, the consensus of which is P-E/V-S-V-P/A-E/V. XRnf12B and XRnf12C may either be paralogs or alleles of XRnf12 because they both share 93% identity with XRnf12 outside of the rep ...
Number 48, 2001 35
Number 48, 2001 35

... defective products produced by genes mutated by RIP could be deleterious and inhibit perithecial development. Finally, alterations in the chromatin structure and / or methylation of large stretches of the genome could affect replication. This idea, which suggests RIP as the cause for barrenness in c ...
Early germline development in Caenorhabditis elegans
Early germline development in Caenorhabditis elegans

... compared to somatic cells; later, they are the only cells to undergo meiosis and gametogenesis. Because the germline is the only lineage to contribute its genetic material to the next generation, it is often referred to as an immortal and totipotent lineage, capable of “outliving” its somatic host t ...
Selection against Accumulating Mutations in Niche
Selection against Accumulating Mutations in Niche

... theoretical issue to understand how evolutionary bifurcation can occur when disruptive selection is opposed by inter-breeding in the population. Focusing on the dichotomy between allopatric and sympatric speciation is questionable; rather there is a plea for research on the speciation processes and ...
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Gene



A gene is a locus (or region) of DNA that encodes a functional RNA or protein product, and is the molecular unit of heredity. The transmission of genes to an organism's offspring is the basis of the inheritance of phenotypic traits. Most biological traits are under the influence of polygenes (many different genes) as well as the gene–environment interactions. Some genetic traits are instantly visible, such as eye colour or number of limbs, and some are not, such as blood type, risk for specific diseases, or the thousands of basic biochemical processes that comprise life.Genes can acquire mutations in their sequence, leading to different variants, known as alleles, in the population. These alleles encode slightly different versions of a protein, which cause different phenotype traits. Colloquial usage of the term ""having a gene"" (e.g., ""good genes,"" ""hair colour gene"") typically refers to having a different allele of the gene. Genes evolve due to natural selection or survival of the fittest of the alleles.The concept of a gene continues to be refined as new phenomena are discovered. For example, regulatory regions of a gene can be far removed from its coding regions, and coding regions can be split into several exons. Some viruses store their genome in RNA instead of DNA and some gene products are functional non-coding RNAs. Therefore, a broad, modern working definition of a gene is any discrete locus of heritable, genomic sequence which affect an organism's traits by being expressed as a functional product or by regulation of gene expression.
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