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TSINGHUA UNIVERSITY Beijing 100084 CHINA
TSINGHUA UNIVERSITY Beijing 100084 CHINA

... Research Center for Beijing Biochip Technology (NERCBBT) Master’s thesis: Detection mRNA of placental origin in maternal plasma by cDNA microarray Supervisor: Liang Zhang and Yuxiang Zhou Backgroud: Noninvasive prenatal diagnosis is a long-sought goal in human genetics. Recent interest in cell-free ...
Crossing-over and Independent Assortment
Crossing-over and Independent Assortment

Learned versus Inherited
Learned versus Inherited

... These factors play an important role in how we act.  Acquired traits are a result of our environment.  Language is an acquired trait ...
Transcription
Transcription

... • transfer RNA (tRNA). RNA molecules that carry amino acids to the growing polypeptide. • small nuclear RNA (snRNA). DNA transcription of the genes for mRNA, rRNA, and tRNA produces large precursor molecules ("primary transcripts") that must be processed within the nucleus to produce the functional ...
Lecture 1 Introduction to Micorarrays and Concepts of Molecular
Lecture 1 Introduction to Micorarrays and Concepts of Molecular

... strand complementary to the DNA template strand by adding dNTPs that are complementary to the template in 5' to 3' direction, condensing the 5'-phosphate group of the dNTPs with the 3'-hydroxyl group at the end of the nascent (extending) DNA strand. The extension time depends both on the DNA polymer ...
File
File

... Gregor Mendel • Founder of genetics (study of heredity) • Monk who lived in a monastery ...
Learned versus Inherited-0
Learned versus Inherited-0

... These factors play an important role in how we act.  Acquired traits are a result of our environment.  Language is an acquired trait ...
17.3 The Process of Speciation
17.3 The Process of Speciation

Observing Patterns in Inherited Traits
Observing Patterns in Inherited Traits

... • http://wps.prenhall.com/esm_freeman_biosci_1/7/1948/4988 46.cw/index.html • Theory became known as the theory of independent assortment • As meiosis ends, genes on pairs of homologous chromosomes have been sorted out for distribution into one gamete or another, independently of gene pairs of other ...
Media Release
Media Release

... PLOS Genetics (http://www.plosgenetics.org) reflects the full breadth and interdisciplinary nature of genetics and genomics research by publishing outstanding original contributions in all areas of biology. We publish human studies, as well as research on model organisms— from mice and flies, to pla ...
PowerPoint Slides
PowerPoint Slides

... places the insertions in CDR-L1 and CDR-H1 at the structurally correct positions. This means that topologically equivalent residues in these loops do get the same label (unlike the Kabat scheme).  The IMGT unique numbering for all IG and TR V-REGIONs of all species relies on the high conservation o ...
Unit 4 ~ DNA Review
Unit 4 ~ DNA Review

... A mutation occurs in an individual, but the individual’s outward appearance does not change. Which of the following statements describes what most likely occurred to produce this result? A. The mutation deleted a portion of a coding section of the DNA. B. The mutation caused a portion of a coding se ...
KEY TERMS FOR Characteristics of Life
KEY TERMS FOR Characteristics of Life

... 4. Compare and contrast DNA and RNA in terms of long name, type of sugar, number of strands, what part of the cell it is found in (nucleus and / or cytoplasm) and names of bases 5. Explain what is actually happening when the DNA unzips. 6. Explain the basic process of translation (where in the cell ...
7.2 Complex Patterns of Inheritance
7.2 Complex Patterns of Inheritance

... (5) multiple alleles • Traits that are controlled by more than 2 alleles, although only two alleles exist in a diploid cell. • Example- Human Blood Types-each person inherits two alleles, one from each parent, but three exist in the human “gene pool”. 4 blood types 3 alleles • Type-A I AI A, I Ai A ...
Leukaemia Section t(10;11)(p12;q23) KMT2A/NEBL Atlas of Genetics and Cytogenetics in Oncology and Haematology
Leukaemia Section t(10;11)(p12;q23) KMT2A/NEBL Atlas of Genetics and Cytogenetics in Oncology and Haematology

... size marker; lane 1, LDI-PCR analysis of der(11) showing the wild-type (wt) band and the der(11) band (asterisk); lane 2, LDIPCR analysis of der(10) showing the wt band and the der(10) band (asterisk). Right: Genomic breakpoint sequence alignment of both derivatives (MLL/NEBL and NEBL/MLL) with resp ...
I. Comparing genome sequences
I. Comparing genome sequences

... • Constrained elements have lower substitution rates than expected from the neutral ra • Contingent on the effect of the mutation and degree of constraint on the function • Manifests as sequence conservation, even among distant species ...
Molecular Basis of the RhCW (Rh8) and RhCX (Rh9) Blood Group
Molecular Basis of the RhCW (Rh8) and RhCX (Rh9) Blood Group

... specificities should not be considered, stricto sensu, as the products of antithetical allelic forms of the RHCE gene, because the substitutions associated with their expression (AI 22Gand G106A, respectively) are not located at the same nucleotide position. Therefore, it cannot be excluded that a v ...
Document
Document

... CMT can generally be classified to demyelinating (CMT1 and 4) and axonal (CMT2) . HNPP is hereditary liability to multiple compression neuropathies with a demyeinating neuropathy. Demyelinating HN result from a variety of mutations in gene encoding proteins related to myelin structure and function ( ...
Biology Curriculum Pacing Guide and Study Guide
Biology Curriculum Pacing Guide and Study Guide

... Autosomal inheritance patterns and characteristics of sickle cell anemia, cystic fibrosis, and Huntington’s disease Solve and interpret co-dominant crosses involving multiple alleles. A, B, AB and O blood types (alleles: IA, IB, and i). Determine if parentage is possible based on blood types. Some t ...
Genetics - MWMS HW Wiki
Genetics - MWMS HW Wiki

... or F2 Generation had both tall and short members: about 3/4th were tall and 1/4th were short. In other words the “lost” trait reappeared in a quarter of the plants. ...
Codominance/Incomplete Dominance
Codominance/Incomplete Dominance

... polygenic trait may be scattered along the same chromosome or located on different chromosomes. ...
Inheritance Practice Quiz
Inheritance Practice Quiz

... Chromosomes Practice Quiz 1. Two strands of DNA are sister chromatids. This means A. They have the exact same sequence B. They contain different versions of the same genes C. They are both recessive D. They are homologous to each other 2. Half of the sons in a very large family are color blind while ...
Document
Document

... F Steps d and e are repeated over and over until the ribosome encounters a stop codon in the mRNA. The mRNA transcript and the new polypeptide chain are released from the ribosome. The two ribosomal subunits separate from each other. Translation is now complete. Either the chain will join the pool o ...
Cloning Disease Genes in the Human Genome
Cloning Disease Genes in the Human Genome

... Cloning a gene is only the first step in finding therapies for disorders. Once a gene  has been identified and cloned, if the gene does not have a known function then  its function has to be determined before any clinical benefits besides diagnostic  testing can be seen. This will likely take longer ...
Homework 4 BSC 1005 Fall 2011
Homework 4 BSC 1005 Fall 2011

... 17.Which of the following represents the sex chromosomes of a typical human female? a. XY b. XXX c. XO d. XX 18.If a sperm containing an X chromosome fertilizes an egg, the child will normally be a. a girl. b. a boy. c. twins, a boy and a girl. d. twin boys. 19.When a gene has the ability to influen ...
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Gene



A gene is a locus (or region) of DNA that encodes a functional RNA or protein product, and is the molecular unit of heredity. The transmission of genes to an organism's offspring is the basis of the inheritance of phenotypic traits. Most biological traits are under the influence of polygenes (many different genes) as well as the gene–environment interactions. Some genetic traits are instantly visible, such as eye colour or number of limbs, and some are not, such as blood type, risk for specific diseases, or the thousands of basic biochemical processes that comprise life.Genes can acquire mutations in their sequence, leading to different variants, known as alleles, in the population. These alleles encode slightly different versions of a protein, which cause different phenotype traits. Colloquial usage of the term ""having a gene"" (e.g., ""good genes,"" ""hair colour gene"") typically refers to having a different allele of the gene. Genes evolve due to natural selection or survival of the fittest of the alleles.The concept of a gene continues to be refined as new phenomena are discovered. For example, regulatory regions of a gene can be far removed from its coding regions, and coding regions can be split into several exons. Some viruses store their genome in RNA instead of DNA and some gene products are functional non-coding RNAs. Therefore, a broad, modern working definition of a gene is any discrete locus of heritable, genomic sequence which affect an organism's traits by being expressed as a functional product or by regulation of gene expression.
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