A method to detect single-nucleotide
... The information on five causal SNPs within the top 5% of SNPs from the ordered LodDiff values are shown. The p-values in the last column are from the familybased association analysis. ...
... The information on five causal SNPs within the top 5% of SNPs from the ordered LodDiff values are shown. The p-values in the last column are from the familybased association analysis. ...
Stanford Encyclopedia of Philosophy
... sociobiology came under critical scrutiny. Both proponents of the hereditary nature of IQ and sociobiologists made a connection between human behavioral traits and genes. Hereditarians in the IQ debates explicitly relied upon heritability analyses such as those introduced above. Critics of sociobiol ...
... sociobiology came under critical scrutiny. Both proponents of the hereditary nature of IQ and sociobiologists made a connection between human behavioral traits and genes. Hereditarians in the IQ debates explicitly relied upon heritability analyses such as those introduced above. Critics of sociobiol ...
The microRNAs of Caenorhabditis elegans
... relative to the independent beat of the larval molts. Although the heterochronic pathway regulates the timing of many events in postembryonic development, it is the seam cell lineage that is most commonly used as a readout for the heterochronic phenotype. Seam cells, named for the way they appear to ...
... relative to the independent beat of the larval molts. Although the heterochronic pathway regulates the timing of many events in postembryonic development, it is the seam cell lineage that is most commonly used as a readout for the heterochronic phenotype. Seam cells, named for the way they appear to ...
Mechanisms and impact of genetic recombination in the evolution of
... distantly related taxa before their divergence into different species are difficult to detect by recombination algorithms because the signals in such loci maybe obscured due to the accumulation of additional point mutations [59]. 5. Contributions of Recombination and Random Mutations Beneficial mutati ...
... distantly related taxa before their divergence into different species are difficult to detect by recombination algorithms because the signals in such loci maybe obscured due to the accumulation of additional point mutations [59]. 5. Contributions of Recombination and Random Mutations Beneficial mutati ...
Proceedings as -file
... Comparison test: Comments from Duty Laboratory South Africa; Comments from Computing Laboratory The Netherlands; Discussion ISAG panels: Do they work well? How many laboratories are using these panels in the routine? Do we need changes? Standard / Reference samples? • Nomenclature: Is there a ne ...
... Comparison test: Comments from Duty Laboratory South Africa; Comments from Computing Laboratory The Netherlands; Discussion ISAG panels: Do they work well? How many laboratories are using these panels in the routine? Do we need changes? Standard / Reference samples? • Nomenclature: Is there a ne ...
Molecular approaches for bacterial azoreductases
... Azo dyes are the dominant types of synthetic dyes, widely used in textiles, foods, leather, printing, tattooing, cosmetics, and pharmaceutical industries. Many microorganisms are able to decolorize azo dyes, and there is increasing interest in biological waste treatment methods. Bacterial azoreducta ...
... Azo dyes are the dominant types of synthetic dyes, widely used in textiles, foods, leather, printing, tattooing, cosmetics, and pharmaceutical industries. Many microorganisms are able to decolorize azo dyes, and there is increasing interest in biological waste treatment methods. Bacterial azoreducta ...
Gene conversion rapidly generates major histocompatibility complex
... evolutionary biology. Genes of the major histocompatibility complex (MHC) are ideal models for studying adaptive genetic variation due to their central role in pathogen recognition. While de novo MHC sequence variation is generated by point mutation, gene conversion can generate new haplotypes by tr ...
... evolutionary biology. Genes of the major histocompatibility complex (MHC) are ideal models for studying adaptive genetic variation due to their central role in pathogen recognition. While de novo MHC sequence variation is generated by point mutation, gene conversion can generate new haplotypes by tr ...
Boundary elements and nuclear organization
... excluded. Thus, positioning an insulator between an enhancer and a promoter results in partitioning of the two into separate functional domains, preventing their proper communication and perhaps causing them to assume incompatible structural traits. Similarly, two insulators can create an independen ...
... excluded. Thus, positioning an insulator between an enhancer and a promoter results in partitioning of the two into separate functional domains, preventing their proper communication and perhaps causing them to assume incompatible structural traits. Similarly, two insulators can create an independen ...
TbMP42 is a structure-sensitive ribonuclease that likely follows a
... Depending on the enrichment protocol, active RNA editing complexes contain as little as 7 (19), 13 (20) or up to 20 polypeptides (21). Protein candidates for every step of the minimal reaction cycle have been identified, thereby confirming the general features of the above-described enzyme-driven reac ...
... Depending on the enrichment protocol, active RNA editing complexes contain as little as 7 (19), 13 (20) or up to 20 polypeptides (21). Protein candidates for every step of the minimal reaction cycle have been identified, thereby confirming the general features of the above-described enzyme-driven reac ...
jsm2003 - University of Wisconsin–Madison
... statistical goal: maximize number of correctly identified QTL ...
... statistical goal: maximize number of correctly identified QTL ...
Male-Biased Mutation Rate and Divergence in Autosomal, Z
... 2000; Bartosch-Härlid et al. 2003); the Z chromosome evolves faster than the W chromosome. There is some variation in the different estimates of avian am (1.7 to 6.5), but the confidence intervals associated with these estimates are large, and so far, all estimates have been based on molecular evol ...
... 2000; Bartosch-Härlid et al. 2003); the Z chromosome evolves faster than the W chromosome. There is some variation in the different estimates of avian am (1.7 to 6.5), but the confidence intervals associated with these estimates are large, and so far, all estimates have been based on molecular evol ...
Traits and Alleles Laboratory
... weather traits controlled by dominant alleles were more common than traits controlled by recessive alleles. The significance behind conducting this lab was to gain a better understanding on why people look the way they do and if there were common trends in which traits were seen more commonly. At th ...
... weather traits controlled by dominant alleles were more common than traits controlled by recessive alleles. The significance behind conducting this lab was to gain a better understanding on why people look the way they do and if there were common trends in which traits were seen more commonly. At th ...
Molecular Evolution, Functional Variation, and Proposed
... Taxonomic Sampling and Collection The representation of taxa in different analyses is summarized in table 2. Our goal was to capture the breadth of diversity within Sicariidae, guided by previous phylogenetic work (Binford et al. 2008, fig. 1). To do this, we include at least one representative of e ...
... Taxonomic Sampling and Collection The representation of taxa in different analyses is summarized in table 2. Our goal was to capture the breadth of diversity within Sicariidae, guided by previous phylogenetic work (Binford et al. 2008, fig. 1). To do this, we include at least one representative of e ...
... into close proximity [11-13]. 3C technology detects interactions between DNA regions by in vivo crosslinking of chromatin and PCR with primers specific for novel junctions created by ligation of sequences that were in close proximity through specific interactions. To determine if the Kcnq1 promoter ...
Agilent Whole Human Genome Oligo Microarray Kit
... Figures A & B depict Agilent’s proven process for ‘superclustering’ and choosing multiple probes within a GeneBin (gene and associated transcripts). In many cases, more than one consensus region will be selected for a given GeneBin. Figure A demonstrates the selection of consensus regions and probes ...
... Figures A & B depict Agilent’s proven process for ‘superclustering’ and choosing multiple probes within a GeneBin (gene and associated transcripts). In many cases, more than one consensus region will be selected for a given GeneBin. Figure A demonstrates the selection of consensus regions and probes ...
PDF
... genetic material (haploid and 'anucleate' embryos obtained by inactivation of one or both of the gametes with X-rays). It was with loach embryos that morphogenetic function of nuclei was studied for the first time using the method of radiation-induced inactivation of nuclei; it was shown that the nu ...
... genetic material (haploid and 'anucleate' embryos obtained by inactivation of one or both of the gametes with X-rays). It was with loach embryos that morphogenetic function of nuclei was studied for the first time using the method of radiation-induced inactivation of nuclei; it was shown that the nu ...
Genetic or epigenetic difference causing discordance between
... For such mechanisms, methylation of the cytosine residue in the DNA molecule, and acetylation, methylation, and other modifications of histones have been well described. These modifications stably affect gene expression through alteration of DNA– protein interaction. These events refer to the inheri ...
... For such mechanisms, methylation of the cytosine residue in the DNA molecule, and acetylation, methylation, and other modifications of histones have been well described. These modifications stably affect gene expression through alteration of DNA– protein interaction. These events refer to the inheri ...
Interval mapping of QTLs controlling yield
... The garden pea (Pisum sativum L.) is one of the most important legume crops in Europe. The majority of agriculturally significant traits in pea, as in other plant species, are inherited quantitatively. The complexity of these phenotypic traits exhibiting continuous variation arises from the segregat ...
... The garden pea (Pisum sativum L.) is one of the most important legume crops in Europe. The majority of agriculturally significant traits in pea, as in other plant species, are inherited quantitatively. The complexity of these phenotypic traits exhibiting continuous variation arises from the segregat ...
SARS Outbreaks in Ontario, Hong Kong and Singapore: the role of
... • Diploid (2n): An organism or cell having two sets of chromosomes or twice the haploid number • Haploid (n): An organism or cell having only one complete set of chromosomes • Gamete: Reproductive cells involved in fertilization. The ovum is the female gamete; the spermatozoon is the male gamete. • ...
... • Diploid (2n): An organism or cell having two sets of chromosomes or twice the haploid number • Haploid (n): An organism or cell having only one complete set of chromosomes • Gamete: Reproductive cells involved in fertilization. The ovum is the female gamete; the spermatozoon is the male gamete. • ...
Topologically Non-linked Circular Duplex DNA
... Although enzyme systems adequate for this task have long since been found and characterized, there have nevertheless arisen a number of proposals for alternative DNA structures in which the strands are topologically non-linked, so that they might separate during replication without having to be unwo ...
... Although enzyme systems adequate for this task have long since been found and characterized, there have nevertheless arisen a number of proposals for alternative DNA structures in which the strands are topologically non-linked, so that they might separate during replication without having to be unwo ...
GAlibLecture
... // we want to use in the GA. The ga doesn't operate on this genome in the // optimization - it just uses it to clone a population of genomes. //Create the genome object GA1DArrayAlleleGenome genome(leng, range, Objective);
//Set appropriate parameters for the genome
genome.initializer(GA1DArray ...
... // we want to use in the GA. The ga doesn't operate on this genome in the // optimization - it just uses it to clone a population of genomes. //Create the genome object GA1DArrayAlleleGenome
Gene targeting: vector design and construction
... – You may need to replace a resistance gene cassette with another one. They are flanked by BamHI. • Vector linearization site. – A cutting site at the end of the homology arm is probably good. – PvuI in pBS (two sites in the vector) : still OK – Unique site in Amp ; still OK – No linearization resul ...
... – You may need to replace a resistance gene cassette with another one. They are flanked by BamHI. • Vector linearization site. – A cutting site at the end of the homology arm is probably good. – PvuI in pBS (two sites in the vector) : still OK – Unique site in Amp ; still OK – No linearization resul ...
Cartesian Genetic Programming
... way, a picture will be produced. In Fig. 2.4, a genotype is shown with a corresponding schematic of the phenotype. The set of function genes and corresponding node functions are shown in Table 2.1. In a later chapter, ways of developing art using CGP will be considered in detail. The functions in Ta ...
... way, a picture will be produced. In Fig. 2.4, a genotype is shown with a corresponding schematic of the phenotype. The set of function genes and corresponding node functions are shown in Table 2.1. In a later chapter, ways of developing art using CGP will be considered in detail. The functions in Ta ...
Sager JJ, Bai Q, Burton EA
... In their recent report (1), Herrera and Jagadeeswaran offer data supporting the use of killifish (annual fish) species over zebrafish as a genetic model for aging. We write to emphasize that, despite the limitations that killifish may circumvent, the zebrafish holds great promise as a model for agin ...
... In their recent report (1), Herrera and Jagadeeswaran offer data supporting the use of killifish (annual fish) species over zebrafish as a genetic model for aging. We write to emphasize that, despite the limitations that killifish may circumvent, the zebrafish holds great promise as a model for agin ...
Gene
A gene is a locus (or region) of DNA that encodes a functional RNA or protein product, and is the molecular unit of heredity. The transmission of genes to an organism's offspring is the basis of the inheritance of phenotypic traits. Most biological traits are under the influence of polygenes (many different genes) as well as the gene–environment interactions. Some genetic traits are instantly visible, such as eye colour or number of limbs, and some are not, such as blood type, risk for specific diseases, or the thousands of basic biochemical processes that comprise life.Genes can acquire mutations in their sequence, leading to different variants, known as alleles, in the population. These alleles encode slightly different versions of a protein, which cause different phenotype traits. Colloquial usage of the term ""having a gene"" (e.g., ""good genes,"" ""hair colour gene"") typically refers to having a different allele of the gene. Genes evolve due to natural selection or survival of the fittest of the alleles.The concept of a gene continues to be refined as new phenomena are discovered. For example, regulatory regions of a gene can be far removed from its coding regions, and coding regions can be split into several exons. Some viruses store their genome in RNA instead of DNA and some gene products are functional non-coding RNAs. Therefore, a broad, modern working definition of a gene is any discrete locus of heritable, genomic sequence which affect an organism's traits by being expressed as a functional product or by regulation of gene expression.