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Chapter 23: Evolution of Populations - Biology E
Chapter 23: Evolution of Populations - Biology E

... If individuals who are heterozygous at a particular locus have greater fitness than do both kinds of homozygotes, they exhibit heterozygote advantage, wherein natural selection tends to maintain two or more alleles at that locus. Since heterozygote advantage is defined by genotype, not phenotype, wh ...
Multiple Choice - 28 points total In each of the questions
Multiple Choice - 28 points total In each of the questions

... A) Prokaryotes carry out both glycolysis and the Krebs cycle in the cytoplasm. B) Eukaryotic cells use more energy to oxidize electron carriers during respiration. C) Eukaryotic enzymes are more efficient in glycolysis than prokaryotic enzymes. D) Prokaryotic cells always require oxygen, while some ...
Gene medication or genetic modification? The devil is in the details
Gene medication or genetic modification? The devil is in the details

... being developed to reduce the fertility of pest animals like the wild Australian rabbit. Similarly, genetic modification is not limited to the addition of heritable properties. The definition of genetic modification of organisms is based on the technology used and not on the intention. In the EU dir ...
Understanding Human Genetic Variation
Understanding Human Genetic Variation

... spot on the slide, scientists can determine how active various genes are in that cell type. Strong fluorescence indicates that many mRNA molecules hybridized to the gene and, therefore, that the gene is very active in that cell type. Conversely, no fluorescence indicates that none of the cell's mRNA ...
Molecular Biology Databases
Molecular Biology Databases

... Karin Verspoor http://www.ploscompbiol.org/article/slideshow.action?uri=info:doi/10.1371/journal.pcbi.1000361&imageURI=info:doi/10.1371/journal.pcbi.1000361.g003 ...
DNA Testing Info
DNA Testing Info

... First a little background. DNA is the genetic material of all higher organisms. It is the blueprint for making and maintaining the animal and consists of a long string of subunits linked together – imagine beads on a wire. In the case of sheep and humans, there are about 3 billion beads (actually nu ...
Use of methylation profiling to identify genes involved in relapse in
Use of methylation profiling to identify genes involved in relapse in

... It is known that genes important in the development of cancer are switched off due to this process and therefore identifying altered DNA methylation patterns can lead to the identification of genes important in cancer development. This project focussed specifically on genes that might be important i ...
Pdf version - Université de Liège
Pdf version - Université de Liège

... The transcription factors involved in coordinating the transcription of DNA into messenger RNA have been known for some time. Recent studies have shown that their role is not limited to these early stages of gene expression. In a study published in Nature Structural & Molecular Biology, a team of re ...
Kostas Konstantinidis - Metagenomics Resources!
Kostas Konstantinidis - Metagenomics Resources!

... Is shotgun metagenomics really useful? ...
Inheritance: Mitosis and Meiosis
Inheritance: Mitosis and Meiosis

... taught in this activity through lecture, hands-on modeling and experimental observation. This activity teaches how the cell maintains proper chromosome number while it replicates, how parents are able to donate half their chromosomes to their offspring, and the relationship between chromosomes and g ...
PPR (pentatricopeptide repeat) proteins in mammals: important aids
PPR (pentatricopeptide repeat) proteins in mammals: important aids

... mutations in the gene encoding this PPR protein, LRPPRC (leucine-rich pentatricopeptide repeat cassette), were shown to cause a rare form of inherited COX (cytochrome c oxidase) deficiency that was termed ‘Leigh Syndrome French-Canadian type’ (or LSFC), as it was found in the population of the Sague ...
Guide to using the PCR lab File
Guide to using the PCR lab File

... gene copy number, two variants that can have significant affects upon the level of this protein and the ability to metabolise certain prescription drugs. CYP2D6 gene analysis The segments of genetic code for the CYP2D6 protein are found in nine exons and the final spliced version of the RNA is calle ...
Chromosome Chromo
Chromosome Chromo

... cells are arrested in mitosis, and are then “harvested” for chromosome analysis After harvesting, the cell preparations are dropped onto glass slides and stained. For most chromosome analyses, a G-banding technique is utilized for staining. Metaphase spread ...
Supplementary Legends
Supplementary Legends

... context (i.e. AxA, AxC, AxG, AxT, CxA, CxC, CxG… TxT, where x is the mutated base), with the different colors indicating the mutation type (i.e. C>A, C>G, C>T, T>A, T>C and T>G). The height of colored bars represents the fraction of mutations attributed in each of the 96 sub-bins. (b) Genetic altera ...
Sex Determination using Polymerase Chain Reaction
Sex Determination using Polymerase Chain Reaction

... amplification [5]. Co-solvent and other additive like dimethyl sulfoxide and formamide also affect to the polymarase chain reaction [5]. In performing of the PCR, primer designing programs are very important [6]. Because of not proper designed prime cannot get the proper result. The most important a ...
Population Genetics:
Population Genetics:

Section 2 Gene Expression in Development and Cell Division
Section 2 Gene Expression in Development and Cell Division

... – The homeoboxes of many eukaryotic organisms appear to be very similar. ...
Global Transposon Mutagenesis and a Minimal Mycoplasma Genome
Global Transposon Mutagenesis and a Minimal Mycoplasma Genome

... Mycoplasma genitalium with 517 genes has the smallest gene complement of any independently replicating cell so far identified. Global transposon mutagenesis was used to identify nonessential genes in an effort to learn whether the naturally occurring gene complement is a true minimal genome under la ...
Chapter 11: Gene Expression PPT
Chapter 11: Gene Expression PPT

... issues associated with gene technologies: genetic engineering, cloning, transgenic organism production, stem cell research, and DNA fingerprinting. ...
Heredity Questions and Answers
Heredity Questions and Answers

... 6. It  is  the  study  of  heredity  and  variation  in  organisms.   7. A  gene  for  which  the  trait  ALWAYS  appears  when   present.     8. A  gene  for  which  the  trait  usually  only  appears  when   there  isn’t  any  dom ...
Presentation
Presentation

... CP 933R CP 933V CP 933U CP 933O CP 933P CP 933K CP 933M ...
Background concepts for sequence analysis Ana, homo
Background concepts for sequence analysis Ana, homo

... Non-symmetry of the BLAST result !  Can be circumvented by using dynamical programming (Smith-Waterman) Problem 2: unequivocal but fake reciprocal best hit •  Duplication followed by a deletion •  Two paralogs can be BBH, but the true orthologs are not present anymore in the genome (due to duplicati ...
Chapter 5 Powerpoint
Chapter 5 Powerpoint

... This trait is sex-linked because the alleles for this trait are carried on the X-chromosome, one of the sex chromosomes. Color-blindness is caused by a recessive allele and because males get only one X-chromosome, they are more likely to be color-blind than females. ...
Genetic Principles
Genetic Principles

... • Synteny – the conservation of blocks of order within two chromosomes that are being compared, usually between species ...
Epigenetics and Inheritance
Epigenetics and Inheritance

... not) when the DNA is being copied during cell division and adding a methyl group to the newly made side of the DNA. It also regulates reactions involving proteins and lipids and controls the processing of chemicals that relay signals in the nervous system (neurotransmitters). Mouse knockouts of the ...
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Gene



A gene is a locus (or region) of DNA that encodes a functional RNA or protein product, and is the molecular unit of heredity. The transmission of genes to an organism's offspring is the basis of the inheritance of phenotypic traits. Most biological traits are under the influence of polygenes (many different genes) as well as the gene–environment interactions. Some genetic traits are instantly visible, such as eye colour or number of limbs, and some are not, such as blood type, risk for specific diseases, or the thousands of basic biochemical processes that comprise life.Genes can acquire mutations in their sequence, leading to different variants, known as alleles, in the population. These alleles encode slightly different versions of a protein, which cause different phenotype traits. Colloquial usage of the term ""having a gene"" (e.g., ""good genes,"" ""hair colour gene"") typically refers to having a different allele of the gene. Genes evolve due to natural selection or survival of the fittest of the alleles.The concept of a gene continues to be refined as new phenomena are discovered. For example, regulatory regions of a gene can be far removed from its coding regions, and coding regions can be split into several exons. Some viruses store their genome in RNA instead of DNA and some gene products are functional non-coding RNAs. Therefore, a broad, modern working definition of a gene is any discrete locus of heritable, genomic sequence which affect an organism's traits by being expressed as a functional product or by regulation of gene expression.
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