A Rapid Chromosome Mapping Method for Cloned Fragments of Yeast DNA.
... behind the 2p mapping method is similar in some ways to other mitotic mapping methods: loss of information from particular chromosomes is detected by the appearance of recessive phenotypes in heterozygous diploids. However, the method differs from other mitotic methods in the way in which chromosome ...
... behind the 2p mapping method is similar in some ways to other mitotic mapping methods: loss of information from particular chromosomes is detected by the appearance of recessive phenotypes in heterozygous diploids. However, the method differs from other mitotic methods in the way in which chromosome ...
Chapter 10: Meiosis
... I. Sexual vs Asexual Reproduction B. Sexual: Offspring product of two genetic donors. 1. Benefit: Genetic recombination. 2. Product of meiosis. 3. Requires (usually) reduction (diploid to haploid) to produce gametes. ...
... I. Sexual vs Asexual Reproduction B. Sexual: Offspring product of two genetic donors. 1. Benefit: Genetic recombination. 2. Product of meiosis. 3. Requires (usually) reduction (diploid to haploid) to produce gametes. ...
Identifying Genes Required for Cell Division in the Early C. elegans
... The oocyte meiotic spindle and the mitotic spindle are necessary to proper cell division and subsequent development of the zygote. The spindle facilitates chromosome segregation to properly distribute genetic information to newly formed daughter cells. Four C. elegans temperature-sensitive mutants a ...
... The oocyte meiotic spindle and the mitotic spindle are necessary to proper cell division and subsequent development of the zygote. The spindle facilitates chromosome segregation to properly distribute genetic information to newly formed daughter cells. Four C. elegans temperature-sensitive mutants a ...
The p53 Protein: From Cell Regulation to Cancer
... I. The Structure and Functions of the p53 Protein. This section (chapters by Aylon and Oren, Chillemi et al., Joruiz and Bourdon, Raj and Attardi, Pfister and Prives, and Aubrey et al.) elucidates and updates new and fundamental observations made over the past few years. II. The Regulation of Cellul ...
... I. The Structure and Functions of the p53 Protein. This section (chapters by Aylon and Oren, Chillemi et al., Joruiz and Bourdon, Raj and Attardi, Pfister and Prives, and Aubrey et al.) elucidates and updates new and fundamental observations made over the past few years. II. The Regulation of Cellul ...
Erythematosus The Epigenetic Face of Systemic Lupus
... are characteristic of different cell types and, in fact, play a key role in defining the transcriptome, which determines the identity of each cell type (2). Two major groups of changes contribute to defining the epigenome of a cell: DNA methylation and histone modifications. The most common form of ...
... are characteristic of different cell types and, in fact, play a key role in defining the transcriptome, which determines the identity of each cell type (2). Two major groups of changes contribute to defining the epigenome of a cell: DNA methylation and histone modifications. The most common form of ...
TaDAD2, a Negative Regulator of Programmed Cell
... identity) to its orthologues from other monocots (Fig. 1A). TaDAD2 shares its highest homology (96% identity) with barley HvDAD2 (Fig. 1B). It also exhibits 78 and 43% sequence identity to Arabidopsis AtDAD1 and human HsDAD1, respectively. The primary structure of TaDAD2 contains three transmembrane ...
... identity) to its orthologues from other monocots (Fig. 1A). TaDAD2 shares its highest homology (96% identity) with barley HvDAD2 (Fig. 1B). It also exhibits 78 and 43% sequence identity to Arabidopsis AtDAD1 and human HsDAD1, respectively. The primary structure of TaDAD2 contains three transmembrane ...
abstracts
... Our HortResearch fruit EST database contains over 160,000 apple sequences from 62 cDNA libraries representing several cultivars and a range of tissues. Exploitation of this resource is supported by a range of enabling technologies, including bioinformatics, biochemistry, physiology, in vivo function ...
... Our HortResearch fruit EST database contains over 160,000 apple sequences from 62 cDNA libraries representing several cultivars and a range of tissues. Exploitation of this resource is supported by a range of enabling technologies, including bioinformatics, biochemistry, physiology, in vivo function ...
Single-molecule studies of DNA replication Geertsema, Hylkje
... Recently, single-molecule approaches have been developed to study the molecular mechanisms underlying DNA replication, in particular lagging-strand polymerase recycling and loop-release mechanisms. Those experiments have begun to elucidate that the replisome is far more dynamic than we have ever tho ...
... Recently, single-molecule approaches have been developed to study the molecular mechanisms underlying DNA replication, in particular lagging-strand polymerase recycling and loop-release mechanisms. Those experiments have begun to elucidate that the replisome is far more dynamic than we have ever tho ...
View/Open - Cadair - Aberystwyth University
... MYB3R1, MYB3R3, and MYB3R5 act redundantly as transcriptional repressors Phylogenetic analysis showed that there are two evolutionarily conserved groups in plant MYB3R family (Fig 1A). One contains MYB3R1 and MYB3R4 (hereafter MYB3R1/4) from Arabidopsis, which were previously shown to act as transcr ...
... MYB3R1, MYB3R3, and MYB3R5 act redundantly as transcriptional repressors Phylogenetic analysis showed that there are two evolutionarily conserved groups in plant MYB3R family (Fig 1A). One contains MYB3R1 and MYB3R4 (hereafter MYB3R1/4) from Arabidopsis, which were previously shown to act as transcr ...
Living Things
... Mutations Mutations can cause a cell to produce an incorrect protein during protein synthesis. As a result, the organism’s trait, or phenotype, may be different from what it normally would have been. ...
... Mutations Mutations can cause a cell to produce an incorrect protein during protein synthesis. As a result, the organism’s trait, or phenotype, may be different from what it normally would have been. ...
Chapter 8
... Bacterial RNA polymerase has five types of subunits. The σ subunit identifies the correct sites for transcription initiation. ...
... Bacterial RNA polymerase has five types of subunits. The σ subunit identifies the correct sites for transcription initiation. ...
Multiple Sequence Alignment
... Make an optimal alignment between a profile and one or more sequences. ...
... Make an optimal alignment between a profile and one or more sequences. ...
Transcription
... in DNA sequencing. It is used to identify the specific DNA sequences that are bound by a particular protein. ...
... in DNA sequencing. It is used to identify the specific DNA sequences that are bound by a particular protein. ...
genetics - Gene In The Title
... At least in some cases, condition may not be mental or emotional http://www.msnbc.msn.com/id/35336470/ns/healthmore_health_news/ # there have been some ‘stutter’ stories in the past few weeks – here is another . . . from an unexpected source --- ...
... At least in some cases, condition may not be mental or emotional http://www.msnbc.msn.com/id/35336470/ns/healthmore_health_news/ # there have been some ‘stutter’ stories in the past few weeks – here is another . . . from an unexpected source --- ...
Precise Gene Disruption in Saccharomyces cerevisiae by Double Fusion Polymerase Chain Reaction.
... must chose a less than optimal configuration, either leaving some of the reading frame intact or removing flanking sequences that may affect the expression of important neighboring genes. Recently a one-step PCR procedure was described for gene disruption in yeast (Baudin et al., 1993; Wach et a/., ...
... must chose a less than optimal configuration, either leaving some of the reading frame intact or removing flanking sequences that may affect the expression of important neighboring genes. Recently a one-step PCR procedure was described for gene disruption in yeast (Baudin et al., 1993; Wach et a/., ...
File formats for NGS data - Bioinformatics Training Materials
... Why do we need to know about reference genomes? ● Allows for genes and genomic features to be evaluated in their genomic context. ○ Gene A is close to gene B ○ Gene A and gene B are within feature C ● Can be used to align shallow targeted high-throughput sequencing to a pre-built map of an organism ...
... Why do we need to know about reference genomes? ● Allows for genes and genomic features to be evaluated in their genomic context. ○ Gene A is close to gene B ○ Gene A and gene B are within feature C ● Can be used to align shallow targeted high-throughput sequencing to a pre-built map of an organism ...
A Complex Suite of Forces Drives Gene Traffic from Drosophila X
... Because previously published analyses of gene duplication from the X chromosome to the autosomes in Drosophila have been limited to only retroposed genes and to only the D. melanogaster genome (Betrán et al. 2002; Dai et al. 2006; Bai et al. 2007), it is unclear whether these patterns of movement h ...
... Because previously published analyses of gene duplication from the X chromosome to the autosomes in Drosophila have been limited to only retroposed genes and to only the D. melanogaster genome (Betrán et al. 2002; Dai et al. 2006; Bai et al. 2007), it is unclear whether these patterns of movement h ...
S5a. Genetic Linkage-Tutorial Problem Set and
... you could do a dihybrid. TAs: you should check student work and encourage them to consider both options, as they will need to be familiar with a testcross and an F1 self. If you do a dihybrid: then you only need to look at data from homozygotes for wilting resistance to see whether you get a 1:2:1 o ...
... you could do a dihybrid. TAs: you should check student work and encourage them to consider both options, as they will need to be familiar with a testcross and an F1 self. If you do a dihybrid: then you only need to look at data from homozygotes for wilting resistance to see whether you get a 1:2:1 o ...
clustering gene expression patterns of fly embryos
... characterize each image. Assume we have N images of in situ expression patterns I1, I2, …, IN , each having M pixels. What is a good way to describe their features? One possible way as proposed in [5] is to detect prominent traits or Gaussian "blobs" in every image. Since different images can have d ...
... characterize each image. Assume we have N images of in situ expression patterns I1, I2, …, IN , each having M pixels. What is a good way to describe their features? One possible way as proposed in [5] is to detect prominent traits or Gaussian "blobs" in every image. Since different images can have d ...
Genetics Notes
... • A Punnett square analysis of the flower-color example demonstrates Mendel’s model. • One in four F2 offspring will inherit two white-flower alleles and produce white flowers. (pp) • Half of the F2 offspring will inherit one white-flower allele and one purple-flower allele and produce purple flower ...
... • A Punnett square analysis of the flower-color example demonstrates Mendel’s model. • One in four F2 offspring will inherit two white-flower alleles and produce white flowers. (pp) • Half of the F2 offspring will inherit one white-flower allele and one purple-flower allele and produce purple flower ...
The structure of a gene co-expression network reveals biological
... to understand the relation between our set of genes (that are under eQTL control), their functions and this phenotype. First, a Moran’s permutation test was performed to assess the correlation between the network structure and the partial correlation values. This test aims at answering the following ...
... to understand the relation between our set of genes (that are under eQTL control), their functions and this phenotype. First, a Moran’s permutation test was performed to assess the correlation between the network structure and the partial correlation values. This test aims at answering the following ...
the molecules of life - Betavak-NLT
... malfunctioning? Molecular biologists and biochemists study the processes inside living cells on the smallest functional level, that of molecules. Molecule malfunction inside a cell can have an enormous impact on the entire organism. Molecular defects lie at the heart of many ailments and diseases in ...
... malfunctioning? Molecular biologists and biochemists study the processes inside living cells on the smallest functional level, that of molecules. Molecule malfunction inside a cell can have an enormous impact on the entire organism. Molecular defects lie at the heart of many ailments and diseases in ...
Gene
A gene is a locus (or region) of DNA that encodes a functional RNA or protein product, and is the molecular unit of heredity. The transmission of genes to an organism's offspring is the basis of the inheritance of phenotypic traits. Most biological traits are under the influence of polygenes (many different genes) as well as the gene–environment interactions. Some genetic traits are instantly visible, such as eye colour or number of limbs, and some are not, such as blood type, risk for specific diseases, or the thousands of basic biochemical processes that comprise life.Genes can acquire mutations in their sequence, leading to different variants, known as alleles, in the population. These alleles encode slightly different versions of a protein, which cause different phenotype traits. Colloquial usage of the term ""having a gene"" (e.g., ""good genes,"" ""hair colour gene"") typically refers to having a different allele of the gene. Genes evolve due to natural selection or survival of the fittest of the alleles.The concept of a gene continues to be refined as new phenomena are discovered. For example, regulatory regions of a gene can be far removed from its coding regions, and coding regions can be split into several exons. Some viruses store their genome in RNA instead of DNA and some gene products are functional non-coding RNAs. Therefore, a broad, modern working definition of a gene is any discrete locus of heritable, genomic sequence which affect an organism's traits by being expressed as a functional product or by regulation of gene expression.