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Nedchromosnotes2jan2014NED 20 KB
Nedchromosnotes2jan2014NED 20 KB

... condition refer to what? Important terms you need to and should know but I do not have time to redefine because they should be hardwired by now are haploid, diploid, nucleosome, chromatin, histone, centromere, telomere, homologues, chromatids. Bacterial genomes = 4.6 Mb = 4.6 x 10^6 bp Human genome ...
Exam 2 Student Key
Exam 2 Student Key

... 5. (6 pts) Imagine there are twin sisters, Abby and Babs. They both inherited mutations in their DNA Polymerase III genes that make the enzyme slightly less efficient at proofreading. Abby gets three different cancers before age 60. Babs never gets cancer. Assume both sisters are accumulating mutati ...
CST review test
CST review test

... number is an even number in each of these organisms? A) It is only a coincidence; many other organisms have an odd number of chromosomes. B) The diploid chromosome number is always even so that when mitosis occurs each new cell gets the same number of chromosomes. C) The diploid chromosome number re ...
lecture 9
lecture 9

Prioritizing Regions of Candidate genes for efficient
Prioritizing Regions of Candidate genes for efficient

... Consideration of parameters resulted in significantly higher discoveries per unit of effort Algorithm can be easily modified and expanded Most useful for large number of candidate genes in large number of patients Select best two or four regions in each candidate gene  Screen all as initial screeni ...
Document
Document

... 6. True or false. The 3’ end of the mRNA made from this region would be located in the 2 kb restriction fragment. 7. True or false. These data indicate that there must be an intron interrupting the coding sequence for this gene within the genomic DNA. Questions 8-9 pertain to the following diagram, ...
Document
Document

... E9. One could begin with the assumption that the inactivation of a tumor-suppressor gene would cause cancerous cell growth. If so, one could begin with a normal human line and introduce a transposon. The next step would be to identify cells that have become immortal. This may be possible by identify ...
E1. Due to semiconservative DNA replication, one of the sister
E1. Due to semiconservative DNA replication, one of the sister

... E9. One could begin with the assumption that the inactivation of a tumor-suppressor gene would cause cancerous cell growth. If so, one could begin with a normal human line and introduce a transposon. The next step would be to identify cells that have become immortal. This may be possible by identify ...
Ch 14 Human Heredity
Ch 14 Human Heredity

... in order of decreasing size. ...
14.1_Human_Chromosomes
14.1_Human_Chromosomes

... in order of decreasing size. ...
G. fortis
G. fortis

... Non-lethal mutations are source of new, potentially beneficial proteins that can be selected for ...
Chapter Nineteen: Genomics
Chapter Nineteen: Genomics

... Homology: For protein-coding genes, the DNA sequence is translated conceptually into the amino acid sequence of the protein. The amino acid sequence of the protein then may yield clues to its function if it is similar to another protein of known function. For example, it is quite easy to recognize h ...
Year 10 Term 3: Genetics
Year 10 Term 3: Genetics

... 5LW3b. identify that during reproduction the transmission of heritable characteristics from one generation to the next involves DNA and genes (ACSSU184) First-hand investigation(s): Genetic Variation in a Human Population 10.3.3 Explain why Mendel’s work in genetics is so highly respected Explain t ...
The Central Dogma of Biology states that DNA codes for RNA, and
The Central Dogma of Biology states that DNA codes for RNA, and

... INITIATION Transcription begins when RNA Polymerase attaches to a PROMOTER on the DNA strand ...
Gene Prediction Gene Prediction Genes Prokaryotic
Gene Prediction Gene Prediction Genes Prokaryotic

... Identify genes from genomic (DNA) sequence Elucidate gene structure ‒ exons, introns, promoter Use gene structure to predict transcripts and polypeptide (protein) sequences ...
Chapter 17 Presentation Transcription and Gene Expression
Chapter 17 Presentation Transcription and Gene Expression

... completely separate from histone methylation, but may also be a way in which genes become inactivated. Evidence: Inactivated X chromosomes are heavily methylated. In many cells that have inactivated genes, the genes are more heavily methylated than in cells where the genes are active. ...
document
document

... Epigenetics is the study of other factors besides the DNA sequence that influence whether or not a gene is transcribed into mRNA and then translated (conversion of mRNA sequence into amino acids) into a protein. An individual’s environment, even in the womb, can influence these factors and permanent ...
File
File

... • Takes place in the nucleus. • A specific gene of DNA is transcribed into mRNA by RNA polymerase. • The instructions for making a protein are transferred from the nucleus to the ribosome. ...
12.2 DNA Replication ppt
12.2 DNA Replication ppt

... DNA polymerase  Action: Adds new nucleotides to the exposed bases using the base-pair rule; also proofreads every connection at this time (avg. 1 error per 2 billion nucleotides)  Result: 2 new double DNA strands are created (but still attached) ...
Bioinformatics course 10.09.15
Bioinformatics course 10.09.15

... Central dogma of molecular biology ...
NonMendelian Inheritance Patterns
NonMendelian Inheritance Patterns

... • Eye color is influenced by many genes coding for different kinds of pigment as well as where in the iris those pigments are found (some have been located on chromosomes 15 & 19) • Think of having 3+ colors from a crayon box and how much and in what order you mix them on a white page dictates the f ...
Slide 1
Slide 1

... GENOTYPE (STARTING POINT), BUT GENES DO NOT DETERMINE HOW THE PERSON WILL END UP (PHENOTYPE) ...
Final exam study guide
Final exam study guide

... to DNA) to prevent genes from being transcribed, therefore preventing the expression of this gene. How is the genetic code written in the DNA? ...
DNA, Genes, and Chromosomes
DNA, Genes, and Chromosomes

... and blue appear in the linear order of the thread. This will illustrate to students how genes appear stacked on chromosomes. 4. Review with students what each material was used to represent the DNA, genes, and chromosomes (thread, colored sections of thread, and thread on spool). 5. Take time now to ...
AS 90729 version 2 Describe genetic processes Level 3 Credits 4
AS 90729 version 2 Describe genetic processes Level 3 Credits 4

... mechanisms for ensuring DNA stability o the effect of point mutations on gene expression DNA needs to be accurately replicated, as it codes for all the polypeptides a cell needs to function. It contains genes, which result in a sequence of amino acids and therefore gives the polypeptides their uniqu ...
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Gene



A gene is a locus (or region) of DNA that encodes a functional RNA or protein product, and is the molecular unit of heredity. The transmission of genes to an organism's offspring is the basis of the inheritance of phenotypic traits. Most biological traits are under the influence of polygenes (many different genes) as well as the gene–environment interactions. Some genetic traits are instantly visible, such as eye colour or number of limbs, and some are not, such as blood type, risk for specific diseases, or the thousands of basic biochemical processes that comprise life.Genes can acquire mutations in their sequence, leading to different variants, known as alleles, in the population. These alleles encode slightly different versions of a protein, which cause different phenotype traits. Colloquial usage of the term ""having a gene"" (e.g., ""good genes,"" ""hair colour gene"") typically refers to having a different allele of the gene. Genes evolve due to natural selection or survival of the fittest of the alleles.The concept of a gene continues to be refined as new phenomena are discovered. For example, regulatory regions of a gene can be far removed from its coding regions, and coding regions can be split into several exons. Some viruses store their genome in RNA instead of DNA and some gene products are functional non-coding RNAs. Therefore, a broad, modern working definition of a gene is any discrete locus of heritable, genomic sequence which affect an organism's traits by being expressed as a functional product or by regulation of gene expression.
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