Krebs, RA and AG Fasolo.
... The recessive X chromosome alleles all produce distinctive phenotypes: white eyes (w, 10.1), miniature wings (m, 36.1), and forked bristles (f, 56.7). T(2;3;)Al-W has multiple inversions superimposed on a translocation between the second and third chromosomes. This translocation is homozygous lethal ...
... The recessive X chromosome alleles all produce distinctive phenotypes: white eyes (w, 10.1), miniature wings (m, 36.1), and forked bristles (f, 56.7). T(2;3;)Al-W has multiple inversions superimposed on a translocation between the second and third chromosomes. This translocation is homozygous lethal ...
pSAT vectors: a modular series of plasmids for autofluorescent
... Assembly of several pSAT expression cassettes into single plasmids For expression of two autofluorescently-tagged proteins from a single plasmid, we first produced pSAT1-ECFP-C1-VIP1 by cloning the VIP1 ORF as a SalI-BamHI fragment from pSAT6EGFP-C1-VIP1 into pSAT1-ECFP-C1. The ECFP-VIP1 expression ...
... Assembly of several pSAT expression cassettes into single plasmids For expression of two autofluorescently-tagged proteins from a single plasmid, we first produced pSAT1-ECFP-C1-VIP1 by cloning the VIP1 ORF as a SalI-BamHI fragment from pSAT6EGFP-C1-VIP1 into pSAT1-ECFP-C1. The ECFP-VIP1 expression ...
J Mol Evol (2007) 65:541–554 - digital
... Table 1 Birds of prey in which MHC class II B genes have been characterised. The number of different exon 2 sequences isolated and the number of individuals analysed per species is also indicated. The codes proposed here will be employed for the naming of the sequences following the nomenclature rec ...
... Table 1 Birds of prey in which MHC class II B genes have been characterised. The number of different exon 2 sequences isolated and the number of individuals analysed per species is also indicated. The codes proposed here will be employed for the naming of the sequences following the nomenclature rec ...
Human cytochromes P450 in health and disease
... Scheme copyrighted by WL Miller. for mammalian P450 enzymes [19]—setting up a case for ‘animal–plant warfare’ being waged, and with P450 genes playing a central role [35]. A form of cytochrome P450 was proposed to be responsible for alveolar hypoxic pulmonary vasoconstriction in dogs [36]. P450-medi ...
... Scheme copyrighted by WL Miller. for mammalian P450 enzymes [19]—setting up a case for ‘animal–plant warfare’ being waged, and with P450 genes playing a central role [35]. A form of cytochrome P450 was proposed to be responsible for alveolar hypoxic pulmonary vasoconstriction in dogs [36]. P450-medi ...
Overview of splicing relevant databases - Stamm
... Alternative splicing concerns more than 90% of human genes [1] and is altered in many diseases [2] see chapter 10, 11 baralle. In order to study gene expression regulation, including splicing regulation, researchers need tools and information to help them guide and interpret their experiments. Alter ...
... Alternative splicing concerns more than 90% of human genes [1] and is altered in many diseases [2] see chapter 10, 11 baralle. In order to study gene expression regulation, including splicing regulation, researchers need tools and information to help them guide and interpret their experiments. Alter ...
Dynamic changes of yak (Bos grunniens) gut microbiota during
... alignment length, and finally we identified a total of 6754 KEGG orthologous groups (KOs). Classifications of ...
... alignment length, and finally we identified a total of 6754 KEGG orthologous groups (KOs). Classifications of ...
Morgan and Linkage
... given that it contains an allele from the original chromosome of interest. The third unit is the centimorgan or cM. One centimorgan is defined as the physical distance corresponding to a value of ✓ equalling 0.01. In other words, it is the distance such that the probability is .01 that a gamete will ...
... given that it contains an allele from the original chromosome of interest. The third unit is the centimorgan or cM. One centimorgan is defined as the physical distance corresponding to a value of ✓ equalling 0.01. In other words, it is the distance such that the probability is .01 that a gamete will ...
Hybrid Sterility and Hybrid Breakdown
... were randomly selected to produce 255 F:I lines (12 F, plants produced <35 seeds and thuswere not used in both genotyping and phenotyping experiments). Seeds ( > X ) from each o f the remaining 255 F-, lines were used to reconstruct the Fy marker genotype and to produce 2418 F., lines (seven to 11 F ...
... were randomly selected to produce 255 F:I lines (12 F, plants produced <35 seeds and thuswere not used in both genotyping and phenotyping experiments). Seeds ( > X ) from each o f the remaining 255 F-, lines were used to reconstruct the Fy marker genotype and to produce 2418 F., lines (seven to 11 F ...
Uria_et_al_2006 _ADH paper
... industries as environmental friendly, economical, and clean catalysts (Wahler and Reymond, 2001). By employing recombinant DNA technology, enzymes can be produced in a relatively short time in quantities that would allow large-scale applications. Using a recently-developed, holistic molecular approa ...
... industries as environmental friendly, economical, and clean catalysts (Wahler and Reymond, 2001). By employing recombinant DNA technology, enzymes can be produced in a relatively short time in quantities that would allow large-scale applications. Using a recently-developed, holistic molecular approa ...
Chapter 11: Complex Inheritance and Human Heredity
... Huntington’s disease The dominant genetic disorder Huntington’s disease affects the nervous system and occurs in one out of 10,000 people in the U.S. The symptoms of this disorder first appear in affected individuals between the ages of 30 and 50 years old. The symptoms include a gradual loss of bra ...
... Huntington’s disease The dominant genetic disorder Huntington’s disease affects the nervous system and occurs in one out of 10,000 people in the U.S. The symptoms of this disorder first appear in affected individuals between the ages of 30 and 50 years old. The symptoms include a gradual loss of bra ...
Phenotypic data in FlyBase
... function beyond predicted functions, and reveals the involvement of gene products in processes without constraint to lists of `candidate genes' about which something is already known. Different alleles, with distinct molecular lesions in or around the transcription unit, may have different mutant ph ...
... function beyond predicted functions, and reveals the involvement of gene products in processes without constraint to lists of `candidate genes' about which something is already known. Different alleles, with distinct molecular lesions in or around the transcription unit, may have different mutant ph ...
Extrachromosomal DNA Transformationof Caenorhabditis elegans
... with 32P-labeled pBR322 DNA, bacteriophage DNA containing a single-copy gene, and bacteriophage DNA containing a fourfold repetitive actin gene sequence (15) (generous gifts of M. Krause). After washing, the hybridization to individual spots was quantitated by liquid scintillation counting. To contr ...
... with 32P-labeled pBR322 DNA, bacteriophage DNA containing a single-copy gene, and bacteriophage DNA containing a fourfold repetitive actin gene sequence (15) (generous gifts of M. Krause). After washing, the hybridization to individual spots was quantitated by liquid scintillation counting. To contr ...
Gene Section MSH6 (mutS homolog 6 (E. Coli)) in Oncology and Haematology
... factor Sp1 were found in the promoter region. This factor is implicated in positioning the RNA polymerase II complex at the transcriptional start sites of promoters lacking TATA- and CAAT-boxes. The proximal promoter region of MSH6 gene also contains several consensus binding sites of the embryonic ...
... factor Sp1 were found in the promoter region. This factor is implicated in positioning the RNA polymerase II complex at the transcriptional start sites of promoters lacking TATA- and CAAT-boxes. The proximal promoter region of MSH6 gene also contains several consensus binding sites of the embryonic ...
Cloning and functional expression of invertebrate connexins from
... junction genes in Ciona reported evidence for seventeen connexin-like sequences and failed to identify any innexin sequences [8]. However, this cursory analysis did not show any data on sequence alignments, provide any figures of molecular phylogeny, discuss gene structure, or most importantly, demon ...
... junction genes in Ciona reported evidence for seventeen connexin-like sequences and failed to identify any innexin sequences [8]. However, this cursory analysis did not show any data on sequence alignments, provide any figures of molecular phylogeny, discuss gene structure, or most importantly, demon ...
The Philosophy of Molecular and Developmental Biology
... Reduction of Mendelian to Molecular Genetics According to the classical account of theory reduction, one theory reduces to another when the laws and generalizations of the first theory can be deduced from those of the second theory with the help of bridge principles relating the vocabularies of the ...
... Reduction of Mendelian to Molecular Genetics According to the classical account of theory reduction, one theory reduces to another when the laws and generalizations of the first theory can be deduced from those of the second theory with the help of bridge principles relating the vocabularies of the ...
Lysines 72, 80 and 213 and aspartic acid 210 of the
... No crystal structure of the L, lactis LacR repressor or any of the other members of the DeoR family is available yet. Therefore, it is impossible to predict the effects of individual mutations on the overall structure and, hence, biological activity of the LacR repressor. An extensive study has been ...
... No crystal structure of the L, lactis LacR repressor or any of the other members of the DeoR family is available yet. Therefore, it is impossible to predict the effects of individual mutations on the overall structure and, hence, biological activity of the LacR repressor. An extensive study has been ...
NIH Public Access
... compounds) and electron acceptors (CO2, nitrate, nitrite, thiosulfate, dimethylsulfoxide, and aromatic carboxyl groups). The genome consists of a single circular 2628784 bp chromosome encoding 2615 open reading frames, which includes 2523 predicted protein-encoding genes. Of these, 1834 genes (70.13 ...
... compounds) and electron acceptors (CO2, nitrate, nitrite, thiosulfate, dimethylsulfoxide, and aromatic carboxyl groups). The genome consists of a single circular 2628784 bp chromosome encoding 2615 open reading frames, which includes 2523 predicted protein-encoding genes. Of these, 1834 genes (70.13 ...
Dissecting plant meiosis using Arabidopsis thaliana mutants
... cells (a mitosis-like division). Agashe et al. (2002) report that in the dyad mutant GUS (b-glucuronidase) expression is driven from a DMC1 promoter during female meiosis suggesting that this division may be meiotic rather than mitotic in nature. Subsequently, these cells can undergo either a second ...
... cells (a mitosis-like division). Agashe et al. (2002) report that in the dyad mutant GUS (b-glucuronidase) expression is driven from a DMC1 promoter during female meiosis suggesting that this division may be meiotic rather than mitotic in nature. Subsequently, these cells can undergo either a second ...
A mRNA localized to the vegetal cortex of Xenopus
... and King, 1988). In this paper, we describe a screening procedure that selects for other mRNAs highly enriched in this cytoskeletal fraction. Here we report on the identification and characterization of one such clone called Xcat-2, an acronym for Xenopus cytoskeletal associated transcripts. Xcat-2, ...
... and King, 1988). In this paper, we describe a screening procedure that selects for other mRNAs highly enriched in this cytoskeletal fraction. Here we report on the identification and characterization of one such clone called Xcat-2, an acronym for Xenopus cytoskeletal associated transcripts. Xcat-2, ...
Hox Genes: Let`s Work Together
... means posteriorly expressed Hox genes can still block the activity of anteriorly expressed Hox gene even in the case of forced expression of anterior Hox gene using different promoter and only translated regions of the gene (Gonzalez-Reyes and Morata, 1990). This convincingly suggests that posterior ...
... means posteriorly expressed Hox genes can still block the activity of anteriorly expressed Hox gene even in the case of forced expression of anterior Hox gene using different promoter and only translated regions of the gene (Gonzalez-Reyes and Morata, 1990). This convincingly suggests that posterior ...
Document
... Presence of Lea antigens is dependant on the inheritance of the Le gene. Presence of Leb antigens is dependant on the inheritance of the Le, H and Se genes. All are necessary to produce Leb antigens. ...
... Presence of Lea antigens is dependant on the inheritance of the Le gene. Presence of Leb antigens is dependant on the inheritance of the Le, H and Se genes. All are necessary to produce Leb antigens. ...
MAK, a computational tool kit for automated MITE
... two identical transposons with symmetric terminals will produce all the four possibilities if all of them are in the specified size range. Two of the desired elements can be easily identified through a BLASTN search. Associator. Because of their short size, MITE families are potentially less disrupt ...
... two identical transposons with symmetric terminals will produce all the four possibilities if all of them are in the specified size range. Two of the desired elements can be easily identified through a BLASTN search. Associator. Because of their short size, MITE families are potentially less disrupt ...
Testis-specific TAF homologs collaborate to control a
... Flies null mutant for can are viable and female fertile but male sterile. The requirement for can function is gene selective: only a specific set of genes normally expressed in wild-type primary spermatocytes are affected, while a number of other genes are transcribed normally in spermatocytes from ...
... Flies null mutant for can are viable and female fertile but male sterile. The requirement for can function is gene selective: only a specific set of genes normally expressed in wild-type primary spermatocytes are affected, while a number of other genes are transcribed normally in spermatocytes from ...
P-Element Transformation with period Locus DNA Restores
... about the molecular nature of the “clocks” underlying such rhythms. The isolation of mutations that perturb or abolish rhythms (reviewed by Feldman, 1982) has allowed molecular analyses of these phenomena. The period (per) locus of Drosophila melanogaster, discovered by Konopka and Benzer (1971) is ...
... about the molecular nature of the “clocks” underlying such rhythms. The isolation of mutations that perturb or abolish rhythms (reviewed by Feldman, 1982) has allowed molecular analyses of these phenomena. The period (per) locus of Drosophila melanogaster, discovered by Konopka and Benzer (1971) is ...
Lab 11. (1 a). Chapter 15. Mendelian Geneticcs
... allele. If an individual possesses two identical alleles, they are said to be homozygous. If an individual possesses two different alleles, they are said to be heterozygous. An individual‘s genetic make-up, or genotype, in turn influences one’s physical characteristics, the phenotype. In many cases, ...
... allele. If an individual possesses two identical alleles, they are said to be homozygous. If an individual possesses two different alleles, they are said to be heterozygous. An individual‘s genetic make-up, or genotype, in turn influences one’s physical characteristics, the phenotype. In many cases, ...
Gene
A gene is a locus (or region) of DNA that encodes a functional RNA or protein product, and is the molecular unit of heredity. The transmission of genes to an organism's offspring is the basis of the inheritance of phenotypic traits. Most biological traits are under the influence of polygenes (many different genes) as well as the gene–environment interactions. Some genetic traits are instantly visible, such as eye colour or number of limbs, and some are not, such as blood type, risk for specific diseases, or the thousands of basic biochemical processes that comprise life.Genes can acquire mutations in their sequence, leading to different variants, known as alleles, in the population. These alleles encode slightly different versions of a protein, which cause different phenotype traits. Colloquial usage of the term ""having a gene"" (e.g., ""good genes,"" ""hair colour gene"") typically refers to having a different allele of the gene. Genes evolve due to natural selection or survival of the fittest of the alleles.The concept of a gene continues to be refined as new phenomena are discovered. For example, regulatory regions of a gene can be far removed from its coding regions, and coding regions can be split into several exons. Some viruses store their genome in RNA instead of DNA and some gene products are functional non-coding RNAs. Therefore, a broad, modern working definition of a gene is any discrete locus of heritable, genomic sequence which affect an organism's traits by being expressed as a functional product or by regulation of gene expression.