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Genetics Problems Part 1 - Lesley Wright - wright
Genetics Problems Part 1 - Lesley Wright - wright

... If I cross my guinea pig with a known heterozygote, then if I get 100% black offspring, I know it was homozygous, and if I get 75% black and 25% white, I know it’s heterozygous. 5. Suppose you were raising what you thought was a purebred line of cats, but found that some of the cats had spots of whi ...
The inversion of the dorsoventral axis in the separation of Bilataria
The inversion of the dorsoventral axis in the separation of Bilataria

... One of the most important discoveries of modern evo-devo research (evolution plus development) is that the embryonic longitudinal axis in animals develops according to the same principle, i.e. controlled by the Hox genes. The Hox genes were initially discovered in Drosophila and have a typical seque ...
Lecture#17 Page 1 BIOLOGY 207 – Dr McDermid Lecture#17
Lecture#17 Page 1 BIOLOGY 207 – Dr McDermid Lecture#17

... 1. Gene loci on the same chromosome may show linkage, not independent assortment. 2. Most linkage between gene loci is not complete because crossing over between loci can occur during meiosis. 3. The extent of linkage between gene loci is expressed as the frequency of recombinant type progeny (vs. p ...
The relation of genetics to physiology and medicine
The relation of genetics to physiology and medicine

... cells. Here we appear to approach a physiological problem, but one that is new and strange to the classical physiology of the schools. We ascribe certain general properties to the genes, in part from genetic evidence and in part from microscopical observations. These properties we may next consider. ...
Bio 4 – Study Guide 3
Bio 4 – Study Guide 3

... karyotype? Compare and contrast mitosis with the first division of meiosis. At what points during meiosis does the potential for genetic variation occur? Chapter 14 & 15 – Mendelian Genetics & Inheritance Who is Mendel? What is a trait? Gene? Know the following terms: dominant, recessive, homozygous ...
CAPT Review Strand V Genetics Evolution Biodiversity revised
CAPT Review Strand V Genetics Evolution Biodiversity revised

...  trace the inheritance of a trait through several generations  is a diagram of family relationships that uses symbols to represent people and lines to represent genetic relationships  may be used to determine the mode of inheritance (dominant, recessive, etc.) of genetic traits ...
The relation of genetics to physiology and medicine
The relation of genetics to physiology and medicine

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MOLECULAR MEDICINE OF THE FUTURE ñ APPLICATIONS AND
MOLECULAR MEDICINE OF THE FUTURE ñ APPLICATIONS AND

... is said to involve around 0.1% of the genomic DNA sequence, which translates into millions of genetic variants among the human population. A significant number of these differences are accounted for by single nucleotide differences (SNPs), otherwise known as single nucleotide polymorphisms, which ar ...
Study of lipid metabolism-related genes as candidate
Study of lipid metabolism-related genes as candidate

... et al., 2012). In addition to the correlation of weight gain with sexual precocity, adipose tissue has been identified as the main site of metabolism of steroid hormones (Siiteri, 1987), a factor related to the onset of reproductive activity. Commercially available high-density DNA microarrays enabl ...
Basic quantitative genetics, the “breeders equation
Basic quantitative genetics, the “breeders equation

... Basic quantitative genetics. The “breeders equation": R =h2S That is: the response to selection (R) is equal to heritability (h2) times the selection differential (S). See Falconer and Mackay p. 160 for why "h2" (it come from Wright, where h was the ratio of standard deviations). The selection diffe ...
Punnett Square Questions
Punnett Square Questions

... You buy a red-bellied newt from a local pet store. You know that red-bellied (R) is dominant to yellow-bellied (r). If you don’t know what the parents of your red-bellied newt look look like, what can you do to determine the genotype of your pet? a) Name the procedure – it is used when trying to det ...
REVIEW WORKSHEET
REVIEW WORKSHEET

... Mom- males get the “y” from their dad so the “X” is always from the mom. What are the chances that their future sons and daughters will get the disease? Show the Punnett Square and give the phenotypic ratios for this cross. ...
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Presentation

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7.013 Problem Set 2 Solutions A C G T
7.013 Problem Set 2 Solutions A C G T

... It is Year 2030, and the first “personned” expedition to Mars is successful. (With the invention of impulse engines and inertial dampers, this is a trivial accomplishment.) A stunning discovery is made: There is life on Mars! There are round, purring, fuzzy, friendly, furry creatures that come in 3 ...
Staggerer_Autism Cerebellum Gene Expression Problem Space
Staggerer_Autism Cerebellum Gene Expression Problem Space

... - Examine genes that have similar gene ontology-classified functions, and predict their interactions - Examine genes that have similar expression patterns (e.g. genes with peak expressions at P7), compare their spatial expression patterns, and predict their interactions - Examine genes that are expr ...
The State of Lake Huron in 2002 – Genetic diversity
The State of Lake Huron in 2002 – Genetic diversity

... current aquatic fish health research is focused on enhanced diagnostics. However, it is important to understand the responses of pathogen populations to selection processes both imposed by the host’s immune system and the natural environment. Selection for specific genotypes that have exhibited grea ...
Modified Mendelian Ratios I
Modified Mendelian Ratios I

... – If trait is dominant, it will not skip generations nor be passed on to offspring unless parents have it. – If trait is recessive, it will skip generations and will exist in carriers. • Form a hypothesis, e.g. autosomal recessive. • Deduce the genotypes. • Check that genotypes are consistent with p ...
1/2 Y 1/2 y 1/2 Y 1/2 y YY Yy Yy yy 1/4 YY + 1/2Yy + 1/4 yy 1 : 2
1/2 Y 1/2 y 1/2 Y 1/2 y YY Yy Yy yy 1/4 YY + 1/2Yy + 1/4 yy 1 : 2

... parents need to be carriers (heterozygous). Therefore, to calculate the chance that an unknown individual will be affected, calculate the chances that the parents will be heterozygous, then multiply these by the chance that the offspring will get both the the mutant alleles. • For rare traits, make ...
The Chromosome Theory of Inheritance
The Chromosome Theory of Inheritance

... Genes, Alleles, and Genotypes • Hereditary determinants for a trait are now called genes. • Mendel also proposed that each individual has two versions of each gene. Today these different versions of a gene are called alleles. Different alleles are responsible for the variation in the traits that Me ...
Inheritance - West East University
Inheritance - West East University

... • they occupy the same locus ...
File - NCEA Level 2 Biology
File - NCEA Level 2 Biology

... Alleles that were originally inherited maternally or paternally (on different homologues) are now recombined on the same chromosome. Variation occurs within chromosomes i.e. new combinations of linked alleles will be ...
From reads to genes in less than 10 R commands
From reads to genes in less than 10 R commands

... When more than one location receives the highest number of votes, we choose the one which has ...
Chapter 8: Genetics
Chapter 8: Genetics

... recessive with no widow’s peak. Chin cleft and widow’s peak are both dominant traits. What are the parent genotypes? How many kids would have both a chin cleft and a widow’s peak? (Dihybrid cross!) 5. Mom and Dad are both heterozygous for freckles and a widow’s peak (both dominant traits). What will ...
B. Intralocular Interactions
B. Intralocular Interactions

... phenotype is the ADDITIVE sum of these multiple genes. Creates continuously variable traits. So here, both genes A and B produce the same pigment. The double homozygote AABB produces 4 ‘doses’ of pigment and is very dark. It also means that there are more ‘intermediate gradations’ that are possible. ...
LINKAGE - TYPES OF LINKAGE AND ESTIMATION OF LINKAGE
LINKAGE - TYPES OF LINKAGE AND ESTIMATION OF LINKAGE

... to the same gamete and the same offspring. Thus, the parental combination of traits is inherited as such by the young one. Incomplete Linkage The genes distantly located in the chromosome show incomplete linkage because they have a chance of separation by crossing over and of going into different ga ...
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Quantitative trait locus

A quantitative trait locus (QTL) is a section of DNA (the locus) that correlates with variation in a phenotype (the quantitative trait). The QTL typically is linked to, or contains, the genes that control that phenotype. QTLs are mapped by identifying which molecular markers (such as SNPs or AFLPs) correlate with an observed trait. This is often an early step in identifying and sequencing the actual genes that cause the trait variation.Quantitative traits are phenotypes (characteristics) that vary in degree and can be attributed to polygenic effects, i.e., the product of two or more genes, and their environment.
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