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Cell-to-cell junctions
Cell-to-cell junctions

... • Structure: Classical cadherins, bind to microfilaments of cytoskeleton • Function: Connects cells together • Oldest form of cell junction • Found in all multicellular organisms ...
Gap junction diseases of the skin
Gap junction diseases of the skin

... Changes in gap junction communication are associated with hyperproliferative disorders such as psoriasis, SCC and delayed wound healing in diabetic skin. ...
Tight Junctions, Desmosomes, and Gap Junctions in Animal Cells
Tight Junctions, Desmosomes, and Gap Junctions in Animal Cells

... • also called anchoring junctions • fasten cells together into strong Sheets • Intermediate filaments made of sturdy keratin proteins anchor desmosomes in the cytoplasm. • Desmosomes attach muscle cells to each other in a muscle. • Some “muscle tears” involve the rupture of desmosomes. ...
Cell Junctions II
Cell Junctions II

... Fibronectin is an extracellular protein that helps cells attach to the matrix ...
Cell junctions
Cell junctions

... •Gap junctions form channels between cells. • Allow ions and small molecules to pass directly from one cell to another. These channels are formed by membrane proteins called connexin. •Six connexins in the cell membrane form a channel called a connexon ...
Notes: Intercellular Junctions
Notes: Intercellular Junctions

... Main Concept: How cells interact, communicate, and connect with eachother. Plants have plasmodesmata that pass through adjoining cell walls. Animal cells have tight junctions, desmonsomes, and gap junctions. Vocab: Plasmodesmata: channels in which plant cell walls are perforated with Tight Junctions ...
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Gap junction



A gap junction may also be called a nexus or macula communicans. When found in nerves they are also referred to as an electrical synapse. While an ephapse has some similarities to a gap junction, by modern definition these two entities are different. Gap junctions are a specialized intercellular connection between a multitude of animal cell-types. They directly connect the cytoplasm of two cells, which allows various molecules, ions and electrical impulses to directly pass through a regulated gate between cells.One gap junction channel is composed of two connexons(or hemichannels), which connect across the intercellular space. Gap junctions are analogous to the plasmodesmata that join plant cells.Gap junctions are expressed in virtually all tissues of the body, with the exception of adult fully developed skeletal muscle and mobile cell types such as sperm or erythrocytes. Gap Junctions, however, are not found in simpler organisms such as sponges and slime molds.
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