The Impact of Ecstasy on the Brain
... occur when taking Ecstasy. • Lacing or substitution in pills make it difficult to predict which effects may occur. • Further studies must be conducted to understand the lasting effects the drugs has on the mind and body. ...
... occur when taking Ecstasy. • Lacing or substitution in pills make it difficult to predict which effects may occur. • Further studies must be conducted to understand the lasting effects the drugs has on the mind and body. ...
A1989U815100001
... a number of receptor subtypes. significantly, drugs that act as 5-HT,s a~Onists,such as 8-OH DPAT, augment rood intake.’ This effect is in keeping with the postulated existence of IA type autoreceptors on the cell bodies ofthe raphe nuclei. This argument keeps intact the major principle of the origi ...
... a number of receptor subtypes. significantly, drugs that act as 5-HT,s a~Onists,such as 8-OH DPAT, augment rood intake.’ This effect is in keeping with the postulated existence of IA type autoreceptors on the cell bodies ofthe raphe nuclei. This argument keeps intact the major principle of the origi ...
Serotonin Syndrome
... Serotonin Syndrome (also called serotonin toxicity or serotonin toxidrome) is not an idiosyncratic drug reaction; it is a predictable consequence of an excess of serotonergic activity at both peripheral and central nervous system receptors. This drug utilization review identified Idaho Medicaid part ...
... Serotonin Syndrome (also called serotonin toxicity or serotonin toxidrome) is not an idiosyncratic drug reaction; it is a predictable consequence of an excess of serotonergic activity at both peripheral and central nervous system receptors. This drug utilization review identified Idaho Medicaid part ...
SSRIs (Selective Serotonin Reuptake Inhibitors) and SNRIs
... believed to have a key role in regulating mood, appetite, anxiety, sleep and may have an effect on memory and learning. Norepinephrine (or noradrenaline) is both a hormone and a brain neurotransmitter. Like Serotonin, it is thought to affect mood and anxiety. SSRIs and SNRIs increase concentrations ...
... believed to have a key role in regulating mood, appetite, anxiety, sleep and may have an effect on memory and learning. Norepinephrine (or noradrenaline) is both a hormone and a brain neurotransmitter. Like Serotonin, it is thought to affect mood and anxiety. SSRIs and SNRIs increase concentrations ...
Ecstasy
... Normal Function of the Neurotransmitter Serotonin… 1. Vesicles in the sending neuron are filled with the neurotransmitter called serotonin. Dopamine plays an important role in mood regulation, appetite and your senses. 2. There are 10 serotonin receptors on the receiving neuron that receive the sero ...
... Normal Function of the Neurotransmitter Serotonin… 1. Vesicles in the sending neuron are filled with the neurotransmitter called serotonin. Dopamine plays an important role in mood regulation, appetite and your senses. 2. There are 10 serotonin receptors on the receiving neuron that receive the sero ...
Serotonin
Serotonin /ˌsɛrəˈtoʊnɨn/ or 5-hydroxytryptamine (5-HT) is a monoamine neurotransmitter. Biochemically derived from tryptophan, serotonin is primarily found in the gastrointestinal tract (GI tract), blood platelets, and the central nervous system (CNS) of animals, including humans. It is popularly thought to be a contributor to feelings of well-being and happiness.Approximately 90% of the human body's total serotonin is located in the enterochromaffin cells in the GI tract, where it is used to regulate intestinal movements. The serotonin is secreted luminally and basolaterally which leads to increased serotonin uptake by circulating platelets and activation after stimulation, which gives increased stimulation of myenteric neurons and gut mobility. The remainder is synthesized in serotonergic neurons of the CNS, where it has various functions. These include the regulation of mood, appetite, and sleep. Serotonin also has some cognitive functions, including memory and learning. Modulation of serotonin at synapses is thought to be a major action of several classes of pharmacological antidepressants.Serotonin secreted from the enterochromaffin cells eventually finds its way out of tissues into the blood. There, it is actively taken up by blood platelets, which store it. When the platelets bind to a clot, they release serotonin, where it serves as a vasoconstrictor and helps to regulate hemostasis and blood clotting. Serotonin also is a growth factor for some types of cells, which may give it a role in wound healing. There are various serotonin receptors.Serotonin is metabolized mainly to 5-HIAA, chiefly by the liver. Metabolism involves first oxidation by monoamine oxidase to the corresponding aldehyde. This is followed by oxidation by aldehyde dehydrogenase to 5-HIAA, the indole acetic acid derivative. The latter is then excreted by the kidneys. One type of tumor, called carcinoid, sometimes secretes large amounts of serotonin into the blood, which causes various forms of the carcinoid syndrome of flushing (serotonin itself does not cause flushing. Potential causes of flushing in carcinoid syndrome include bradykinins, prostaglandins, tachykinins, substance P, and/or histamine), diarrhea, and heart problems. Because of serotonin's growth-promoting effect on cardiac myocytes, a serotonin-secreting carcinoid tumour may cause a tricuspid valve disease syndrome, due to the proliferation of myocytes onto the valve.In addition to animals, serotonin is found in fungi and plants. Serotonin's presence in insect venoms and plant spines serves to cause pain, which is a side-effect of serotonin injection. Serotonin is produced by pathogenic amoebae, and its effect on the gut causes diarrhea. Its widespread presence in many seeds and fruits may serve to stimulate the digestive tract into expelling the seeds.