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PopGen2: Linkage Disequilibrium
PopGen2: Linkage Disequilibrium

... We have seen that under Hardy-Weinberg conditions the genotypes AA, Aa, and aa will occur in the proportions p2, 2pq, and q2 (where p + q = 1) after just one generation of random mating. This is a random association of alleles within genotypes. Consider a second autosomal locus with alleles B and b, ...
Transcript  - Howard Hughes Medical Institute
Transcript - Howard Hughes Medical Institute

... to try to roughly estimate the number of genetic factors that underlie the major architectural differences between maize and teosinte. 10. How many genes result in maize/teosinte differences? (12:05) In the simplest possible world, if all the differences between maize and teosinte were due to a simp ...
Deer Colors
Deer Colors

... So rare are albino deer that generations of American Indians thought them to be magical. The Indians had no way of knowing that all living things have cells, and within those cells are chromosomes and genes. Genes are what make us unique. Albino deer have recessive genes. Both parents must carry the ...
Specialized adaptation of a lactic acid bacterium to the milk
Specialized adaptation of a lactic acid bacterium to the milk

... absent or truncated in the LMD-9 genome, or are involved in other physiological functions relevant to the adaptation towards dairy environment. In addition, only 17 of the LMD-9 specific ORFs have closest orthologs with the pathogenic streptococci. Most of these genes encode for unknown proteins and ...
A Haploid System of Sex Determination in the Brown Alga - Hal-CEA
A Haploid System of Sex Determination in the Brown Alga - Hal-CEA

... it from the XY and ZW systems described above [10], exhibits specific evolutionary and genetic properties that have no exact equivalent in diploid systems. In UV systems, the female and male SDR haplotypes function in independent, haploid, male and female, individuals and consequently there is no he ...
Meiosis: vive la difference! Peter Shaw* and Graham Moore
Meiosis: vive la difference! Peter Shaw* and Graham Moore

... and yeast [15•], the chromosomes are in a Rabl configuration prior to meiosis, that is, with the centromeres clustered at one pole and telomeres spread around the other pole. This is not absolutely required for meiosis, however, as other species, such as mouse and human, do not display a clear Rabl ...
PDF
PDF

... morphogenetic inactivity of cell nuclei. This would seem paradoxical if the nuclei are supposed to be the sole site for RNA synthesis. This paradox might be resolved, however, if the 'early' RNA synthesis were partly or entirely independent of the cell nuclei. We attempted to clarify this point by m ...
Punnett Squares
Punnett Squares

... Every individual offspring inherits at least two copies of every gene – one from the mother and one from the father. ...
Microbial Gene Transfer: An Ecological
Microbial Gene Transfer: An Ecological

Punnett Squares
Punnett Squares

... Every individual offspring inherits at least two copies of every gene – one from the mother and one from the father. ...
Correlation of length of VNTR alleles at the X
Correlation of length of VNTR alleles at the X

... many males had problems with impulsive, aggressive and hypersexual behaviors due to a hemizygous chain termination mutation in the MAOA gene. This was consistent with the numerous other studies suggesting a correlation between low MAO levels and impulsive, risk-taking, externalizing behaviors. Becau ...
ACEMBL System:
ACEMBL System:

... Protein complexes are the heart and soul of many cellular processes 1 . Some researchers go as far as describing the cell as “a collection of protein machines”2. Whether you think of replication, transcription 3 , translation 4 , DNA repair, the processing, import, trafficking as well as export of p ...
The role of Cdx genes in the mammalian gut
The role of Cdx genes in the mammalian gut

... the newly established intestinal phenotype. Another possibility is that the protein pump promoter used may be active at low levels in cells other than fully differentiated oxyntic cells expressing the proton pump. Clearly, these are speculative suggestions that require rigorous investigation. Subseq ...
Commonly Used STR Markers
Commonly Used STR Markers

... • Ability to resolve all alleles clearly: – Easier to resolve 4 base pair difference – Rather than 3, 3 better than 2, etc ...
Balancer Chromosomes – An Optional Minitutorial What follows is a
Balancer Chromosomes – An Optional Minitutorial What follows is a

... This cross would yield three possible genotypes, Cy/Cy (all die), Cy/m (live unless m is a dominant lethal; these flies have the curly wings) and m/m (might survive; but won’t have the curly wings). The fact that there are inversions built into the balancer chromosome means that crossover cannot occ ...
Pleurochrysome: A Web Database of
Pleurochrysome: A Web Database of

... selecting multiple species will provide information on all UNIGENEs assigned with at least one orthologous gene in any species selected. For a more rigorous search for orthologous genes, the ‘Advanced Orthologous Gene Search’ is available from a link located at the bottom left of the search and resu ...
Ectocarpus
Ectocarpus

Risks from GMOs due to Horizontal Gene Transfer
Risks from GMOs due to Horizontal Gene Transfer

... recipient cell. (2) MGEs can alter the function of genes in the vicinity of the insertion in the host genome. These alterations can include disruption or inactivation of genes at the site of insertion. Conversely, insertional mutagenesis by an MGE can also result in benefits to the host such as prov ...
Primary ciliary dyskinesia: genes, candidate genes
Primary ciliary dyskinesia: genes, candidate genes

... would be released on the left side of the node, where the flow remains the strongest. Data supporting the ciliary fluid flow hypothesis come from the studies of murine inversus viscerum (iv) mutants, harboring mutations in a ciliary component, the left-right dynein (the protein product of lrd) (Lowe ...
Familial Adenomatous Polyposis (FAP)
Familial Adenomatous Polyposis (FAP)

... letters which have been wrongly copied which causes the gene not to work. The genetics team will try to work this out for each family, and if we find the "spelling" mistake we will offer a test to the rest of the family to find out who has it and who has not. Blood cells contain copies of all your g ...
Classifying Gene Expression Data using an Evolutionary Algorithm
Classifying Gene Expression Data using an Evolutionary Algorithm

... genes that may be used to predict class membership for new samples. First, supervised classification identifies a set of genes that can differentiate different classes of samples by using the training dataset with known classes. Then, the selected set of discriminative genes, or predictive genes, is ...
The Evolution of Vertebrate Sex Chromosomes
The Evolution of Vertebrate Sex Chromosomes

... researchers interpreted them in the context of the theories built on Muller’s ideas. Pairing ...
A deflationary account of information in biology - Philsci
A deflationary account of information in biology - Philsci

... thermodynamic entropy. However, in communication theory it enables engineers to measure the probability that the received signal is equivalent to the transmitted signal. Shannon entropy, also called Shannon-Weaver information, after the text by Claude Shannon and Warren Weaver (Shannon and Weaver 19 ...
Genome-Wide Identification of Allelic Expression in Hypertensive
Genome-Wide Identification of Allelic Expression in Hypertensive

... context12 that can contribute to relatively large within group variances that reduce statistical power and can lead to type II error. In the present studies using radiotelemetry measurements we observed that SHR-A3 have higher blood pressure than the F2 progeny of an SHR-A3⫻SHR-B2 cross (Table 1). H ...
Fact Sheet 52|HAEMOPHILIA WHAT IS HAEMOPHILIA
Fact Sheet 52|HAEMOPHILIA WHAT IS HAEMOPHILIA

... Our body is made up of millions of cells, and in each cell there are instructions, called genes, that make all the necessary structural components and chemicals for the body to function. These genes are packaged onto little long strands known as chromosomes. We all have 46 chromosomes arranged into ...
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Epigenetics of human development

Development before birth, including gametogenesis, embryogenesis, and fetal development, is the process of body development from the gametes are formed to eventually combine into a zygote to when the fully developed organism exits the uterus. Epigenetic processes are vital to fetal development due to the need to differentiate from a single cell to a variety of cell types that are arranged in such a way to produce cohesive tissues, organs, and systems.Epigenetic modifications such as methylation of CpGs (a dinucleotide composed of a 2'-deoxycytosine and a 2' deoxyguanosine) and histone tail modifications allow activation or repression of certain genes within a cell, in order to create cell memory either in favor of using a gene or not using a gene. These modifications can either originate from the parental DNA, or can be added to the gene by various proteins and can contribute to differentiation. Processes that alter the epigenetic profile of a gene include production of activating or repressing protein complexes, usage of non-coding RNAs to guide proteins capable of modification, and the proliferation of a signal by having protein complexes attract either another protein complex or more DNA in order to modify other locations in the gene.
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