Significance analysis of microarrays (SAM)
... • SAM gives estimates of the False Discovery Rate (FDR), which is the proportion of genes likely to have been wrongly identified by chance as being significant. • It is a very interactive algorithm – allows users to dynamically change thresholds for significance (through the tuning parameter delta) ...
... • SAM gives estimates of the False Discovery Rate (FDR), which is the proportion of genes likely to have been wrongly identified by chance as being significant. • It is a very interactive algorithm – allows users to dynamically change thresholds for significance (through the tuning parameter delta) ...
Huntington`s disease - patient information
... This leaflet is written for people who have a family history of Huntington disease (HD) and would like to understand more about the condition. HD affects the central nervous system. It is caused by a gene expansion on chromosome four. The protein product of the expanded HD gene damages nerve cells ...
... This leaflet is written for people who have a family history of Huntington disease (HD) and would like to understand more about the condition. HD affects the central nervous system. It is caused by a gene expansion on chromosome four. The protein product of the expanded HD gene damages nerve cells ...
Cell Structure and Function
... mathematically related to the distance between them • The further apart 2 genes are the higher the probability of a crossing over event separating them • Recombination frequencies vary between 0% and 50% • This method is useful for establishing gene maps (location of genes on a chromosome • Example: ...
... mathematically related to the distance between them • The further apart 2 genes are the higher the probability of a crossing over event separating them • Recombination frequencies vary between 0% and 50% • This method is useful for establishing gene maps (location of genes on a chromosome • Example: ...
Genomic conflicts: the concept Genomic conflict: Cytoplasmic male
... A further consequence of genetic recombination is that genes may differ in their mode of inheritance. This creates the potential for genomic (or genetic) conflicts. They occur when genes have only partially overlapping interests. For example, genes in the nucleus and genes in the mitochondria are in ...
... A further consequence of genetic recombination is that genes may differ in their mode of inheritance. This creates the potential for genomic (or genetic) conflicts. They occur when genes have only partially overlapping interests. For example, genes in the nucleus and genes in the mitochondria are in ...
Historical Genetics George Mendel Mendel`s Experiment
... The allele for the phenotype of blue eyes is “b” The allele for the phenotype of brown eyes is “B” A Blue eyed in individual can only be “bb” because blue eyes are recessive. An individual with Brown eyes can Have either “BB” or “Bb” because because brown eyes are dominant ...
... The allele for the phenotype of blue eyes is “b” The allele for the phenotype of brown eyes is “B” A Blue eyed in individual can only be “bb” because blue eyes are recessive. An individual with Brown eyes can Have either “BB” or “Bb” because because brown eyes are dominant ...
REPRODUCTION and GENETICS
... genes from only one parent, they are identical genetically to that parent. • One-celled organisms such as bacteria reproduce asexually by dividing in two. • Hydra reproduce asexually in a process called budding. ...
... genes from only one parent, they are identical genetically to that parent. • One-celled organisms such as bacteria reproduce asexually by dividing in two. • Hydra reproduce asexually in a process called budding. ...
GENE 760 -â Problem Set #3
... ANS: What is the difference between gene level and isoform level expression values? When could gene levels expression values be misleading? Gene-‐level expression values report the expression levels for the ...
... ANS: What is the difference between gene level and isoform level expression values? When could gene levels expression values be misleading? Gene-‐level expression values report the expression levels for the ...
Document
... The genomes of mitochondria 1. Mitochondrial DNA (mtDNA) lies within the matrix, it appears in highly condensed structure called nucleoids. The mtDNA of most cells does not reside in a single location. 2. The number of mitochondria, nucleoids, and mtDNA molecules are variable. The mechanisms are no ...
... The genomes of mitochondria 1. Mitochondrial DNA (mtDNA) lies within the matrix, it appears in highly condensed structure called nucleoids. The mtDNA of most cells does not reside in a single location. 2. The number of mitochondria, nucleoids, and mtDNA molecules are variable. The mechanisms are no ...
w latach 2016-2018 na Wydziale Biologii Uniwersytetu im. Adama
... material known as meiotic recombination or crossover (CO). This process is required for proper chromosome segregation, therefore it is obligatory for each chromosome pair. CO is also the basic source of genetic variation within natural populations as it creates new arrangements of alleles. For this ...
... material known as meiotic recombination or crossover (CO). This process is required for proper chromosome segregation, therefore it is obligatory for each chromosome pair. CO is also the basic source of genetic variation within natural populations as it creates new arrangements of alleles. For this ...
Nucleic Acids: Revisiting the Central Dogma
... The molecular hallmarks of lin-4, the founding member of the microRNA family. Sequence complementarity between lin-4 (red) and the 3'-untranslated region (UTR) of lin-14 mRNA (blue). lin-4 is partially complementary to 7 sites in the lin-14 3' UTR; its binding to these sites of complementarity bring ...
... The molecular hallmarks of lin-4, the founding member of the microRNA family. Sequence complementarity between lin-4 (red) and the 3'-untranslated region (UTR) of lin-14 mRNA (blue). lin-4 is partially complementary to 7 sites in the lin-14 3' UTR; its binding to these sites of complementarity bring ...
Chpt 9: How Genes Work DNA is your genetic material, it makes up
... central dogma: information is transferred from DNA to RNA to protein all info for life is coded for in the DNA, which stays in the nucleus, so it is transferred to RNA, which gets it to the cytoplasm to the cell's machinery, which then makes proteins remember the mouse eye/fly eye transfer experimen ...
... central dogma: information is transferred from DNA to RNA to protein all info for life is coded for in the DNA, which stays in the nucleus, so it is transferred to RNA, which gets it to the cytoplasm to the cell's machinery, which then makes proteins remember the mouse eye/fly eye transfer experimen ...
Mechanisms of Genetic exchange
... 4. The DNA transferred will usually replace homologous genes already present within the recipient cell. Homologous DNA is that coding for the same characteristic in general, but is not identical. For example, different bacteria produce flagellin proteins with different amino acid sequences. The gene ...
... 4. The DNA transferred will usually replace homologous genes already present within the recipient cell. Homologous DNA is that coding for the same characteristic in general, but is not identical. For example, different bacteria produce flagellin proteins with different amino acid sequences. The gene ...
DNA Replication
... • Deletion mutation--piece of chromosome breaks off and is lost; the new DNA strands are also missing a piece • Duplication--piece of chromosome breaks off and is inserted on homologous chromosome • Translocation--piece of chromosome breaks off and attaches to a different, non-homologous chromosome ...
... • Deletion mutation--piece of chromosome breaks off and is lost; the new DNA strands are also missing a piece • Duplication--piece of chromosome breaks off and is inserted on homologous chromosome • Translocation--piece of chromosome breaks off and attaches to a different, non-homologous chromosome ...
Chapter 20 - BEHS Science
... DNA Cloning Gene cloning allows scientists to work with small sections of DNA (single genes) in isolation. – Exactly what does the gene code for? Much of a DNA molecule is noncoding, and scientists are mostly interested in the genes. Cloning makes identical copies of the same gene (or genes) ...
... DNA Cloning Gene cloning allows scientists to work with small sections of DNA (single genes) in isolation. – Exactly what does the gene code for? Much of a DNA molecule is noncoding, and scientists are mostly interested in the genes. Cloning makes identical copies of the same gene (or genes) ...
Genes and training for athletic performance
... ability to respond well to training. Claude Bouchard and coworkers based their early work on analysis of performance within and between families, including twins in some studies. The group is now looking at the association between specific DNA sequences and performance. So far they have found little ...
... ability to respond well to training. Claude Bouchard and coworkers based their early work on analysis of performance within and between families, including twins in some studies. The group is now looking at the association between specific DNA sequences and performance. So far they have found little ...
Blue Box PowerPoint Presentation Template
... • DNA segment with known location on a chromosome whose inheritance can be followed • DNA segments near each other on a chromosome tend to be inherited together ...
... • DNA segment with known location on a chromosome whose inheritance can be followed • DNA segments near each other on a chromosome tend to be inherited together ...
genotype-phenotype mapping
... The left box shows what we know about NewWorms' genes. The right box shows the genetic makeup of two NewWorms. Use this information to solve the problems below. Two NewWorm Genotypes ...
... The left box shows what we know about NewWorms' genes. The right box shows the genetic makeup of two NewWorms. Use this information to solve the problems below. Two NewWorm Genotypes ...
08MicrobialGenetExamIIAnswers
... Incompatible because the plasmids both utilize the same proteins to regulate when its origins of replication fire, one plasmid is likely to be replicated more frequently than the other. This may be because its origin has slightly higher affinity for the initiation proteins, it is smaller and therefo ...
... Incompatible because the plasmids both utilize the same proteins to regulate when its origins of replication fire, one plasmid is likely to be replicated more frequently than the other. This may be because its origin has slightly higher affinity for the initiation proteins, it is smaller and therefo ...
Mechanisms of Evolution (on
... • Examples of Genetic Drift • Genetic drift refers to the change in a type of genes in a population due to a random occurrence. In other words, a random circumstance causes a certain genetic trait to become more common or rarer over time. Occurrences of Genetic Drift: • Genetic drift can be seen in ...
... • Examples of Genetic Drift • Genetic drift refers to the change in a type of genes in a population due to a random occurrence. In other words, a random circumstance causes a certain genetic trait to become more common or rarer over time. Occurrences of Genetic Drift: • Genetic drift can be seen in ...
Presentation
... – phages that carry bacterial genes from 1 host cell to another – generalized~ random transfer of host cell chromosome – specialized~ incorporation of prophage DNA into host chromosome ...
... – phages that carry bacterial genes from 1 host cell to another – generalized~ random transfer of host cell chromosome – specialized~ incorporation of prophage DNA into host chromosome ...
Using Statistical Design and Analysis to Detect
... We are interested in testing H0: v1 = v2, whether a given gene is differentially expressed between M and B cells or not. ...
... We are interested in testing H0: v1 = v2, whether a given gene is differentially expressed between M and B cells or not. ...
Genetics and Heredity
... Individual nests of birds may not turn out exactly like this, but if there are many baby birds, they will work out genetically with the ratios 1:2:1. ...
... Individual nests of birds may not turn out exactly like this, but if there are many baby birds, they will work out genetically with the ratios 1:2:1. ...
Moving on from old dichotomies: beyond nature^nurture towards a
... There are yet other factors that affect diagnosis, though they are less frequently spoken about: economic, social and historical criteria ± or even fashion. Thus Warner has explained the rather broader criteria for the diagnosis of schizophrenia as opposed to manic depression previously employed in ...
... There are yet other factors that affect diagnosis, though they are less frequently spoken about: economic, social and historical criteria ± or even fashion. Thus Warner has explained the rather broader criteria for the diagnosis of schizophrenia as opposed to manic depression previously employed in ...