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... Now that LacI has been removed for the operator, RNA polymerase can proceed with transcription 8. Label the following diagram. ...
Zinc-Finger Proteins Required for Pairing and Synapsis
Zinc-Finger Proteins Required for Pairing and Synapsis

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USMLE Step 1 Web Prep — Transcription and RNA Processing: Part

... the promoter region . The bacterial promoter contains two “consensus” sequences (sequences of DNA), called the –35 sequence and the TATA box (at –10)- Pribnow box.( use sigma factor to initiate transcription) Transcription begins at the +1 base pair. Transcription terminates once RNA polymerase read ...
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... Many times based on Methylation ( -CH3) of C in DNA Methylation of C in C-p-G Island - often at gene promoters Degree of Chromatin Compaction - modification of DNA Highly compacted - add methyl groups - 'OFF' blocks accessibility for transcription enzymes Loosely compacted - lose methyl groups - 'ON ...
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Answers to Mastering Concepts Questions
Answers to Mastering Concepts Questions

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Epigenetics of human development

Development before birth, including gametogenesis, embryogenesis, and fetal development, is the process of body development from the gametes are formed to eventually combine into a zygote to when the fully developed organism exits the uterus. Epigenetic processes are vital to fetal development due to the need to differentiate from a single cell to a variety of cell types that are arranged in such a way to produce cohesive tissues, organs, and systems.Epigenetic modifications such as methylation of CpGs (a dinucleotide composed of a 2'-deoxycytosine and a 2' deoxyguanosine) and histone tail modifications allow activation or repression of certain genes within a cell, in order to create cell memory either in favor of using a gene or not using a gene. These modifications can either originate from the parental DNA, or can be added to the gene by various proteins and can contribute to differentiation. Processes that alter the epigenetic profile of a gene include production of activating or repressing protein complexes, usage of non-coding RNAs to guide proteins capable of modification, and the proliferation of a signal by having protein complexes attract either another protein complex or more DNA in order to modify other locations in the gene.
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