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genome - Microme
genome - Microme

... InterproScan (domains and functional sites), COGnitor (COG protein ...
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The Big Picture: A Review of Biology Chemistry of Life

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... stored in DNA is used to produce a functional gene product. Gene products are either proteins or noncoding RNAs, such as tRNA and rRNA, which play essential roles in protein syn­ thesis, but do not code for proteins. Gene expression is regu­ lated throughout the lifespan of an individual cell to con ...
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... The only limited success stories so far have been associated with the ex vivo procedure, which avoids most of the risks of in vivo procedures. In April 2002, a team in London’s Great Ormond Street Hospital used gene therapy to cure a child with X-linked severe combined immunodeficiency disease. This ...
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... showing the extreme expression of the trait. If 2 genes involved = 1/16 If 3 genes involved = 1/64 So you can develop a formula to determine the number of genes (1/2)2N where N = number of genes So if you solve for N you can determine the number of genes involved. ...
The Big Picture: A Review of Biology
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...  1. Transcription: DNA in the nucleus is used to make messenger RNA (mRNA) o DNA has all the directions the cell needs to live  2. RNA moves out into the cytoplasm o RNA carries the directions to other parts of the cell  3. Translation: The RNA attaches to a ribosome and directs the production of ...
The Big Picture
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...  1. Transcription: DNA in the nucleus is used to make messenger RNA (mRNA) o DNA has all the directions the cell needs to live  2. RNA moves out into the cytoplasm o RNA carries the directions to other parts of the cell  3. Translation: The RNA attaches to a ribosome and directs the production of ...
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... What is Myb ?  Myb is derived from “myeloblastosis”, which is a name for a specific type of leukemia.  This gene was first recognized as the v-Myb oncogene of the avian myeloblastosis virus.  Family of transcription factors containing 2 or 3 repeat sequences in the DNA-binding domain (Myb domain ...
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... • Many definitions – Precision important for specific studies – Working definition: • alcohol craving has become encompassing drive • Individual is losing, or has lost, job, family, health ...
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Epigenetics of human development

Development before birth, including gametogenesis, embryogenesis, and fetal development, is the process of body development from the gametes are formed to eventually combine into a zygote to when the fully developed organism exits the uterus. Epigenetic processes are vital to fetal development due to the need to differentiate from a single cell to a variety of cell types that are arranged in such a way to produce cohesive tissues, organs, and systems.Epigenetic modifications such as methylation of CpGs (a dinucleotide composed of a 2'-deoxycytosine and a 2' deoxyguanosine) and histone tail modifications allow activation or repression of certain genes within a cell, in order to create cell memory either in favor of using a gene or not using a gene. These modifications can either originate from the parental DNA, or can be added to the gene by various proteins and can contribute to differentiation. Processes that alter the epigenetic profile of a gene include production of activating or repressing protein complexes, usage of non-coding RNAs to guide proteins capable of modification, and the proliferation of a signal by having protein complexes attract either another protein complex or more DNA in order to modify other locations in the gene.
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