Animal Behaviour SPECIAL ISSUE: KIN SELECTION
... grouped into three major behavioural contexts: foraging, aggression and behavioural maturation. The model results led to a prediction that some transcription factors regulate brain gene expression across the three major behavioural contexts while others regulate gene expression in just one or two be ...
... grouped into three major behavioural contexts: foraging, aggression and behavioural maturation. The model results led to a prediction that some transcription factors regulate brain gene expression across the three major behavioural contexts while others regulate gene expression in just one or two be ...
Oral squamous cell carcinoma (OSCC) – molecular, viral and
... tetrahydrocannabinol is still not clear [15]. Oncogenes and tumour suppressor genes. An oncogene is a kind of abnormal gene that predisposes cells to develop into cancers. Their correct version (proto-oncogenes) are commonly found in human genetic material and perform the functions necessary to main ...
... tetrahydrocannabinol is still not clear [15]. Oncogenes and tumour suppressor genes. An oncogene is a kind of abnormal gene that predisposes cells to develop into cancers. Their correct version (proto-oncogenes) are commonly found in human genetic material and perform the functions necessary to main ...
What is a functional genetic polymorphism?
... or biochemical endophenotypes with genetic polymorphisms or sequence variants (following recommendations of the Human Genome Variation Society, “sequence variant” is a more inclusive term than “polymorphism.” However, a common problem has been a lack of consistent association with a given polymorphi ...
... or biochemical endophenotypes with genetic polymorphisms or sequence variants (following recommendations of the Human Genome Variation Society, “sequence variant” is a more inclusive term than “polymorphism.” However, a common problem has been a lack of consistent association with a given polymorphi ...
Deprivation of protein or amino acid induces C/EBPβ synthesis and
... codons within the sequence, such that three protein isoforms are produced [16]. Human LAP* and LAP (liver-enriched activating protein) are 345 and 322 amino acids in length respectively, whereas LIP (liver-enriched inhibitory protein) represents the Cterminus of LAP*/LAP and is 147 amino acids long. ...
... codons within the sequence, such that three protein isoforms are produced [16]. Human LAP* and LAP (liver-enriched activating protein) are 345 and 322 amino acids in length respectively, whereas LIP (liver-enriched inhibitory protein) represents the Cterminus of LAP*/LAP and is 147 amino acids long. ...
Chronic Myeloid Leukemia
... Corey, S., Cortes, J. (2010). Chronic Myeloid Leukemia: Pathophysiology and Therapeutics. Deniniger, M., Goldman, J., Melo, J. (2000). The Molecular Biology of Chronic Myeloid Leukemia. Blood, 96(10), 3343 - 3356. Druker, B. (2008). Translation of the Philadelphia chromosome into therapy for CML. Bl ...
... Corey, S., Cortes, J. (2010). Chronic Myeloid Leukemia: Pathophysiology and Therapeutics. Deniniger, M., Goldman, J., Melo, J. (2000). The Molecular Biology of Chronic Myeloid Leukemia. Blood, 96(10), 3343 - 3356. Druker, B. (2008). Translation of the Philadelphia chromosome into therapy for CML. Bl ...
Identification of a novel streptococcal gene cassette mediating
... autocatalytic cleavage of the Ala84-Gly85 bond of LexA, which disrupts its ability to dimerize (35, 57). Self-cleavage of LexA inactivates LexA as a repressor, which induces the expression of SOS genes. SOS mutagenesis is mainly mediated by errorprone polymerases and takes place under severe conditi ...
... autocatalytic cleavage of the Ala84-Gly85 bond of LexA, which disrupts its ability to dimerize (35, 57). Self-cleavage of LexA inactivates LexA as a repressor, which induces the expression of SOS genes. SOS mutagenesis is mainly mediated by errorprone polymerases and takes place under severe conditi ...
Reduction in DNA Binding Activity of the Transcription Factor Pax
... Pax-5 transcripts can generate at least three additional splice variants, named Pax-5b, 5d, and 5e (30). In resting, splenic B cells, the protein level of Pax-5b is very low (M. Lowen and P. Zwollo, unpublished observations) and Pax-5e is not present at detectable levels (30). In contrast, isoform P ...
... Pax-5 transcripts can generate at least three additional splice variants, named Pax-5b, 5d, and 5e (30). In resting, splenic B cells, the protein level of Pax-5b is very low (M. Lowen and P. Zwollo, unpublished observations) and Pax-5e is not present at detectable levels (30). In contrast, isoform P ...
Complete genome sequence of Roseophage vB_DshP
... The Roseobacter clade is representative of the most abundant bacteria in the oceans of the world, typically accounting for up to 25% of all marine microbial communities [1–3]. Roseobacters are versatile in their metabolism, employing diverse catalytic processes in a range of environmentally releva ...
... The Roseobacter clade is representative of the most abundant bacteria in the oceans of the world, typically accounting for up to 25% of all marine microbial communities [1–3]. Roseobacters are versatile in their metabolism, employing diverse catalytic processes in a range of environmentally releva ...
Recurrent patterns of DNA copy number alterations in tumors reflect
... of samples, we plot the pan-cancer PC1-3 gene loadings in Fig. 1C and Appendix Fig. S1C. As the reviewer anticipated, the pan-cancer PC1 separates diploid from aneuploid tumors (Appendix Fig. S1B; the PC1 loadings are similar to the tumor type-specific signatures A, as can be seen in the revised Fig ...
... of samples, we plot the pan-cancer PC1-3 gene loadings in Fig. 1C and Appendix Fig. S1C. As the reviewer anticipated, the pan-cancer PC1 separates diploid from aneuploid tumors (Appendix Fig. S1B; the PC1 loadings are similar to the tumor type-specific signatures A, as can be seen in the revised Fig ...
Promega Notes: Technically Speaking: Tips for Working with RNA
... Q: If RNases are not permanently denatured by autoclaving, how do I eliminate them? Glassware and other utensils used in RNA purification must be baked at 180-200°C for at least 4 hours to eliminate active nucleases. Utensils that will not withstand these temperatures must be treated with 1% hydroge ...
... Q: If RNases are not permanently denatured by autoclaving, how do I eliminate them? Glassware and other utensils used in RNA purification must be baked at 180-200°C for at least 4 hours to eliminate active nucleases. Utensils that will not withstand these temperatures must be treated with 1% hydroge ...
Chromosomal Microarray Analysis
... – No gain or loss of chromosomal material was detected in the regions tested – A gain or loss was detected that is known / expected to be benign (i.e. does not cause disease) • Abnormality detected – A gain or loss of chromosomal material known to result in a defined genetic condition has been detec ...
... – No gain or loss of chromosomal material was detected in the regions tested – A gain or loss was detected that is known / expected to be benign (i.e. does not cause disease) • Abnormality detected – A gain or loss of chromosomal material known to result in a defined genetic condition has been detec ...
Abstract
... genomics, the next coming challenge will be directed towards understanding the function of all genes as well as proceeding rice functional genomic analysis. The achievements in rice functional genomics will also provide valuable information to the functional analysis of other cereals. Transcriptomic ...
... genomics, the next coming challenge will be directed towards understanding the function of all genes as well as proceeding rice functional genomic analysis. The achievements in rice functional genomics will also provide valuable information to the functional analysis of other cereals. Transcriptomic ...
AQF 613 - RUFORUM
... The dominant S allele produces the scaled phenotype (SS and Ss genotypes), while the recessive s allele produces the reduced scale phenotype called “mirror” (ss genotype). The N. gene modifies the phenotypes produced by the S gene. There are two alleles at the N locus. The dominant N allele modifies ...
... The dominant S allele produces the scaled phenotype (SS and Ss genotypes), while the recessive s allele produces the reduced scale phenotype called “mirror” (ss genotype). The N. gene modifies the phenotypes produced by the S gene. There are two alleles at the N locus. The dominant N allele modifies ...
Partial Sequence Analysis of the 5S to 18S rRNA Gene Region of
... The organization and structure of the rRNA genes in plant mitochondria are different from those of animals and fungi. In plant mitochondria, rRNA genes are larger and a 5S RNA is found in mitochondrial ribosomes (6, 15). The 5S and 18S rRNA genes in plant mtDNA are closely linked (3, 10, 12), but bo ...
... The organization and structure of the rRNA genes in plant mitochondria are different from those of animals and fungi. In plant mitochondria, rRNA genes are larger and a 5S RNA is found in mitochondrial ribosomes (6, 15). The 5S and 18S rRNA genes in plant mtDNA are closely linked (3, 10, 12), but bo ...
Sexual Reproduction: Meiosis
... • But, new combinations can just as often be bad as good… • May also provide a backup set of information for DNA repair ...
... • But, new combinations can just as often be bad as good… • May also provide a backup set of information for DNA repair ...
Practical exon and gene quantification in R
... Ex 1) For how many regions are described in the GTF file? (the dimensions of a data.frame can be queried with the nrow and ncol functions) The first, third, fourth, fifth, and ninth columns are of particular interest as these contain the chromosome, element type, start, end and name of the various e ...
... Ex 1) For how many regions are described in the GTF file? (the dimensions of a data.frame can be queried with the nrow and ncol functions) The first, third, fourth, fifth, and ninth columns are of particular interest as these contain the chromosome, element type, start, end and name of the various e ...
IJBT 11(2) 220-223
... step PCR or two step nested-PCR under low stringent condition, indicating the presence of at least two DRB genes. Presence of multi DRB genes (3) was also reported by Schwaiger et al9. The existence of several DRB genes in other artiodactyla species reinforces this hypothesis. However, in present st ...
... step PCR or two step nested-PCR under low stringent condition, indicating the presence of at least two DRB genes. Presence of multi DRB genes (3) was also reported by Schwaiger et al9. The existence of several DRB genes in other artiodactyla species reinforces this hypothesis. However, in present st ...
What can whole genome expression data tell us about the ecology
... The fact that gene expression is a phenotype and represents an instantaneous snapshot of the proteins that are being made in that specific tissue at that particular time means that great care must be taken when selecting the time and location of sampling. Studying the molecular basis of behavioural ...
... The fact that gene expression is a phenotype and represents an instantaneous snapshot of the proteins that are being made in that specific tissue at that particular time means that great care must be taken when selecting the time and location of sampling. Studying the molecular basis of behavioural ...
Why Some People Prefer Pickle Juice: The
... pregnancy-induced hypertension (the mechanism of which, ironically, was characterized while studying an adolescent boy who suffered from significantly elevated blood pressure). The last three of these diseases all cause hypertension, and until recently, physicians could do little more than haphazard ...
... pregnancy-induced hypertension (the mechanism of which, ironically, was characterized while studying an adolescent boy who suffered from significantly elevated blood pressure). The last three of these diseases all cause hypertension, and until recently, physicians could do little more than haphazard ...
Extraction of Gene-Disease Relations from Medline Using Domain
... too many relations that are dependent only on the co-occurrence information; so many of their results may be unreliable. They have done only a preliminary analysis on the precision of the outputs. There are some studies that employ various NLP techniques in order to obtain high-precision knowledge f ...
... too many relations that are dependent only on the co-occurrence information; so many of their results may be unreliable. They have done only a preliminary analysis on the precision of the outputs. There are some studies that employ various NLP techniques in order to obtain high-precision knowledge f ...
The nuclear envelope in genome organization, expression and
... INM or lamin protein29. These studies revealed that transcriptionally silent chromosomal domains are more likely to interact with perinuclear landmarks such as lamins in both flies and humans20,21. These domains are poor in active chromatin marks, are flanked by regions enriched in insulator protein ...
... INM or lamin protein29. These studies revealed that transcriptionally silent chromosomal domains are more likely to interact with perinuclear landmarks such as lamins in both flies and humans20,21. These domains are poor in active chromatin marks, are flanked by regions enriched in insulator protein ...
NIH Public Access
... When Ludwig Plate introduced the term pleiotropy in 1910(11,12) molecular biology was completely unknown. Since that time several diverse mechanisms underlying pleiotropy have been described. As these molecular stories unfold, they reveal how tightly interconnected and complex biomolecular networks ...
... When Ludwig Plate introduced the term pleiotropy in 1910(11,12) molecular biology was completely unknown. Since that time several diverse mechanisms underlying pleiotropy have been described. As these molecular stories unfold, they reveal how tightly interconnected and complex biomolecular networks ...
The Arabidopsis RAD51 paralogs RAD51B, RAD51D and XRCC2
... Our results provide strong evidence that Arabidopsis XRCC2, RAD51B and RAD51D have complex functions in somatic DNA repair and gene regulation, arguing for further studies of these ancient genes that have been maintained in both plants and animals during their long evolutionary history. ...
... Our results provide strong evidence that Arabidopsis XRCC2, RAD51B and RAD51D have complex functions in somatic DNA repair and gene regulation, arguing for further studies of these ancient genes that have been maintained in both plants and animals during their long evolutionary history. ...
Chapter 10 Meiosis
... Meiosis I secondary oocyte (n, and large in size) plus polar body (n and small in size) Meiosis II one large ovum (n), plus three polar bodies (n, small) (dissolved back in the body) – The single ovum is the only cell capable of being fertilized by a sperm, the polar bodies wither and die ...
... Meiosis I secondary oocyte (n, and large in size) plus polar body (n and small in size) Meiosis II one large ovum (n), plus three polar bodies (n, small) (dissolved back in the body) – The single ovum is the only cell capable of being fertilized by a sperm, the polar bodies wither and die ...
P D G E
... the data regardless of the exact values. This occurs if there is a pattern of coregulation for a subset of genes and conditions. Expression can occur at different levels, so e.g. if two genes are up-regulated by different degrees, (e.g. due to a specific condition), these are said to experience cohe ...
... the data regardless of the exact values. This occurs if there is a pattern of coregulation for a subset of genes and conditions. Expression can occur at different levels, so e.g. if two genes are up-regulated by different degrees, (e.g. due to a specific condition), these are said to experience cohe ...