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High-resolution haplotype structure in the human genome
High-resolution haplotype structure in the human genome

... marker in LD with a true causal SNP located some distance (perhaps several genes) away. Once the haplotype blocks are defined, however, it is straightforward to examine a subset of SNPs that uniquely distinguish the common haplotypes in each block (shown elsewhere in this issue)20. This allows the c ...
PhoB by Phosphate Stress and Controlled by
PhoB by Phosphate Stress and Controlled by

... hybridizing cosmid p7C9 was subcloned in part or in full into pBluescript KS(1) and pCPP30 for sequencing and complementation experiments, respectively. The S. meliloti phoB gene from strain 104A14 was previously cloned on a 2.3-kb HindIII fragment (2), and for experiments in this study this fragmen ...
Daisy quorum drives for the genetic restoration of wild
Daisy quorum drives for the genetic restoration of wild

... choose whether to collaborate or compete intelligently. For example, if any readers are interested in pursuing these ideas, we would be more than happy to advise, collaborate, or desist in our own efforts as appropriate; we have no desire to duplicate the work of others given the many other urgent p ...
Allelic Variation at the Rht8 Locus in a 19th
Allelic Variation at the Rht8 Locus in a 19th

... of our PCR products yielded fragments that were sized a few base pairs larger than WMS261-164 bp or WMS261-174 bp, but in accordance with Schmidt et al. [9] we did not consider them as distinct alleles, but a result of slippage or “stutter”. Our choice of samples is in many ways comparable with thos ...
Specialized Transduction
Specialized Transduction

... the host chromosome (abnormal excision; Fig. 1). Subsequent work has shown that prophage insertion requires a phage-encoded site-specific recombinase, integrase, that promotes recombination between the phage attachment site, attP, and attB (see chapter 125). Integrase also promotes excision by recom ...
The role of Dby mRNA in early development of male mouse zygotes
The role of Dby mRNA in early development of male mouse zygotes

... Ejaculated mammalian spermatozoa contain a complex yet specific population of mRNA. However, the possible roles that mRNA has in early zygotic and embryonic development remain unclear. We found that Dby mRNA is selectively retained in capacitated mouse spermatozoa, and is transferred into the oocyte ...
NIH Public Access
NIH Public Access

... which is the model acetogenic bacterium that has been widely used for elucidating the WoodLjungdahl pathway of CO and CO2 fixation. This pathway, which is also known as the reductive acetyl-CoA pathway, allows acetogenic (often called homoacetogenic) bacteria to convert glucose stoichiometrically in ...
WHITE PANICLE1, a Val-tRNA Synthetase
WHITE PANICLE1, a Val-tRNA Synthetase

... phenotype during early leaf development. Seedlings showing the severe albino phenotype (wp1s) died when they reached the four-leaf stage (Fig. 1A, a–b; Supplemental Figure S1A), while wp1 seedlings showing the weak virescent phenotype (wp1w) could reach the flowering stage when they displayed white p ...
Detection of mutation status of IgVH genes and minimal residual
Detection of mutation status of IgVH genes and minimal residual

... present in the heavy chain locus (adopted from Essential Immunology, Roitt, I.M. et Delves, PJ.) ...
Recombination and clonal groupings within Helicobacter pylori from
Recombination and clonal groupings within Helicobacter pylori from

... bacteria from different continents or that particular alleles are selected for in certain populations. However, a different segment of the vacA gene was found to have recombined freely in bacteria isolated from Canada and South Africa (Suerbaum et al ., 1998). The virulence-associated cagA gene enco ...
PDF - Oxford Academic - Oxford University Press
PDF - Oxford Academic - Oxford University Press

... longevity conducted in the Leiden Longevity Study identified the ApoE E4 isoform as deleterious to longevity that was confirmed in an independent GWAS of long-lived individuals of German descent. Notably, no other genetic loci for longevity have been identified in these GWAS. To examine the conserve ...
Query Results
Query Results

... Query Results: Each tag can have a label (if the user provided it), which is displayed in this field. This could be useful to highlight some specific tags of interest, or for example, to see the cluster group number of each tag. The user can provide any label here. This field is optional and can be ...
SARS Outbreaks in Ontario, Hong Kong and Singapore: the role of
SARS Outbreaks in Ontario, Hong Kong and Singapore: the role of

... • Diploid (2n): An organism or cell having two sets of chromosomes or twice the haploid number • Haploid (n): An organism or cell having only one complete set of chromosomes • Gamete: Reproductive cells involved in fertilization. The ovum is the female gamete; the spermatozoon is the male gamete. • ...
Number 48, 2001 35
Number 48, 2001 35

... defective products produced by genes mutated by RIP could be deleterious and inhibit perithecial development. Finally, alterations in the chromatin structure and / or methylation of large stretches of the genome could affect replication. This idea, which suggests RIP as the cause for barrenness in c ...
genotype AND phenotype
genotype AND phenotype

... Ronnie has a deep voice.  Is this genotype or phenotype? Explain how you know. Brandy has one allele for being tall, and one allele for being short.  Is this genotype or phenotype? Explain how you know. ...
Gene Section SIL (SCL/TAL1 interrupting locus) Atlas of Genetics and Cytogenetics
Gene Section SIL (SCL/TAL1 interrupting locus) Atlas of Genetics and Cytogenetics

... Department of Pediatric Hemato-Oncology, Cancer Research Center, Sheba Medical Center, Tel-Hashomer, ...
4b. Pedigree Analysis in Humans
4b. Pedigree Analysis in Humans

... dominating over any affected allele - If it were X-linked dominant, I1 could not have an unaffected daughter (II4) as an affected father will always pass on the disease to his daughter – occurs because she must inherit the only X-chromosome that her father has, which carries the trait (b) Autosomal ...
Extensive tRNA gene changes in synthetic Brassica
Extensive tRNA gene changes in synthetic Brassica

... generation (12.4%). In summary, tRNA-gene-associated sequences varied most from the F1 to F2 generation, and more novel/duplicated sequences than eliminated sequences were observed during the Brassica allopolyploidization process. In addition, bands could be divided into 20 groups according to the ...
Genome partitioning of genetic variation for complex traits using
Genome partitioning of genetic variation for complex traits using

... total genetic variance. An alternative to hypothesis testing is to focus on the estimation of the variance explained by all SNPs together. Recently, we showed how this may be done and estimated that ~45% of phenotypic variation for human height is accounted for by common SNPs from a sample of ~4,000 ...
A, B, a
A, B, a

... Chapter 6 Genetic Recombination in Eukaryotes Linkage and genetic diversity ...
Genetics of Clubroot Resistance inBrassicaSpecies | SpringerLink
Genetics of Clubroot Resistance inBrassicaSpecies | SpringerLink

... genotypes to race 6 of P. brassicae. Crute and others (1980) also demonstrated that three genes controlled resistance in turnip. This suggests that clubroot resistance in B. rapa is controlled by several genes independently. Because clubroot-resistant cultivars of Chinese cabbage were released by in ...
understanding heredity
understanding heredity

... form different groups which can readily be distinguished and which transmit their several distinctive traits to their offspring. Think, for example, of African Negroes, Asiatic Mongolian people, and E~ropean Whites. Their characters, like skin and eye color, though not species characters of man, are ...
PPT File
PPT File

... – At the metaphase plate, there are paired homologous chromosomes (tetrads), instead of individual replicated chromosomes – At anaphase I, it is homologous chromosomes, instead of sister chromatids, that separate ...
PDF
PDF

... heterogeneous surface receptors collectively referred to as PfEMP1. These proteins are encoded by a large, polymorphic gene family called var. The family contains approximately 60 individual genes, which are subject to strict, mutually exclusive expression, with the single expressed var gene determi ...
Genetic and Molecular Diagnostics – Next Generation Sequencing
Genetic and Molecular Diagnostics – Next Generation Sequencing

... Cardiovascular Risk Assessment (L36362) (Applies to the indicated performing laboratory) See the bulleted non-covered list, and the specific bullet for the CardiaRisk™ test found within the LCD. For the gene MMADHC:  Palmetto GBA MolDX Excluded Test List (M00047) Use the provided “.xlsx” ...
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Genomic imprinting

Genomic imprinting is the epigenetic phenomenon by which certain genes are expressed in a parent-of-origin-specific manner. If the allele inherited from the father is imprinted, it is thereby silenced, and only the allele from the mother is expressed. If the allele from the mother is imprinted, then only the allele from the father is expressed. Forms of genomic imprinting have been demonstrated in fungi, plants and animals. Genomic imprinting is a fairly rare phenomenon in mammals; most genes are not imprinted.In insects, imprinting affects entire chromosomes. In some insects the entire paternal genome is silenced in male offspring, and thus is involved in sex determination. The imprinting produces effects similar to the mechanisms in other insects that eliminate paternally inherited chromosomes in male offspring, including arrhenotoky.Genomic imprinting is an inheritance process independent of the classical Mendelian inheritance. It is an epigenetic process that involves DNA methylation and histone methylation without altering the genetic sequence. These epigenetic marks are established (""imprinted"") in the germline (sperm or egg cells) of the parents and are maintained through mitotic cell divisions in the somatic cells of an organism.Appropriate imprinting of certain genes is important for normal development. Human diseases involving genomic imprinting include Angelman syndrome and Prader–Willi syndrome.
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